445 results match your criteria nanofibers building

Molecular Cage-Mediated Radial Gradient Porous Sponge Nanofiber for Selective Adsorption of a Mustard Gas Simulant.

ACS Appl Mater Interfaces 2021 Sep 24. Epub 2021 Sep 24.

Innovation Center for Textile Science and Technology, College of Textiles, Donghua University, Shanghai 201620, China.

Poisons and poisonous weapons in armed conflict, especially chemical warfare agents (CWAs), pose serious threats to global security. Porous materials have recently been regarded as promising candidates to defend personnel in a CWA-contaminated environment, but challenges remain for integrating these materials into protective garments without sacrificing the intrinsic flexibility of fibers. Here, we report a rigid-flexible coupling hypercross-linking methodology to create flexible sponge-like nanofibers featuring hierarchical radial gradient porous nanoarchitectures, in which the inner structure is a mesoporous multichambered network, and the outer structure is a dense domain with a microporous network structure. Read More

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September 2021

Preparation of Fucoidan-Based Electrospun Nanofibers and Their Interaction With Endothelial Cells.

Front Bioeng Biotechnol 2021 6;9:739209. Epub 2021 Sep 6.

Department of Stomatology, Institute for Translational Medicine, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.

Sulfated polysaccharide fucoidan (FD) is widely applied in biomedical applications owing to its outstanding bioactivities. In addition to the biochemical features, the architecture of biomaterials plays a critical role in tissue repair and regeneration. Particularly, nanofibers have elicited great interest due to their extracellular matrix-like structure, high specific surface area, and favorable biological properties. Read More

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September 2021

Magneto- and opto-stimuli responsive nanofibers as a controlled drug delivery system.

Nanotechnology 2021 Sep 15. Epub 2021 Sep 15.

Department of Bioengineering, University of California Riverside, 900 University Avenue, 331 Materials Science and Engineering Building, Riverside, California, 92521, UNITED STATES.

The drawbacks of conventional drug administration include repeated administration, non-specific biodistribution in the body's systems, the long-term unsustainability of drug molecules, and high global cytotoxicity, posing a challenge for the efficient treatment of chronic diseases that require varying drug dosages over time for optimal therapeutic efficacy. Most controlled release methods encapsulate drug molecules in biodegradable materials that dissolve over time to release the drug, making it difficult to deliver drugs on a schedule. To address these limitations, we developed a magneto-, opto-stimuli responsive drug delivery system based on functionalized electrospun nanofibers loaded with superparamagnetic iron oxide nanoparticles (SPIONs). Read More

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September 2021

Fabrication and Photocatalytic Properties of Electrospun Fe-Doped TiO Nanofibers Using Polyvinyl Pyrrolidone Precursors.

Polymers (Basel) 2021 Aug 7;13(16). Epub 2021 Aug 7.

Department of Advanced Materials Engineering, Gangneung-Wonju National University, Gangneung 25457, Korea.

For the removal of pollutants, a modified TiO photocatalyst is attracting attention. Fe-doped TiO nanofibers were prepared through a combination of electrospinning and calcination. Morphological characterization of the sample was conducted using field-emission scanning electron and transmission electron microscopy. Read More

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Deconstruction and Reassembly of Renewable Polymers and Biocolloids into Next Generation Structured Materials.

Chem Rev 2021 Aug 20. Epub 2021 Aug 20.

Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, P.O. Box 16300, FI-00076 Aalto, Finland.

This review considers the most recent developments in supramolecular and supraparticle structures obtained from natural, renewable biopolymers as well as their disassembly and reassembly into engineered materials. We introduce the main interactions that control bottom-up synthesis and top-down design at different length scales, highlighting the promise of natural biopolymers and associated building blocks. The latter have become main actors in the recent surge of the scientific and patent literature related to the subject. Read More

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Atomistic insights into the structure of heptapeptide nanofibers.

J Chem Phys 2021 Aug;155(5):055101

Departament de Química, Universitat Autònoma de Barcelona, Bellaterra 08193, Spain.

Artificial amyloid-like nanofibers formed from short peptides are emerging as new supramolecular structures for catalysis and advanced materials. In this work, we analyze, by means of computational approaches, the preferred atomistic fibrillar architectures that result from the self-assembly of polar NY7, NF7, SY7, SF7, and GY7 peptides into steric zippers formed by two β-sheets (describing an individual steric zipper) and by four β-sheets. For all heptapeptides, except GY7, parallel β-sheet organizations with polar residues packed at the steric zipper appear to be the preferred assemblies for the two β-sheets system due to the formation of a strong network of hydrogen bonds. Read More

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Cellulose Nanofibers from Olive Tree Pruning as Food Packaging Additive of a Biodegradable Film.

Foods 2021 Jul 7;10(7). Epub 2021 Jul 7.

BioPrEn Group, Chemical Engineering Department, Marie-Curie Building, Universidad de Córdoba, 14014 Córdoba, Spain.

A biodegradable packaging film containing cellulose nanofibers from olive tree pruning, a by-product of olives production, was obtained using a solvent casting method. Nanocellulose was added to polyvinyl alcohol (PVA) to enhance the technological properties of the composite film as food packaging material. Nanocellulose was obtained from unbleached and bleached pulp through a mechanical and TEMPO pretreatment. Read More

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Spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of biomimetic nanofiber-enabled bone tissue engineering.

Biomaterials 2021 09 26;276:121041. Epub 2021 Jul 26.

Center for Musculoskeletal Research, University of Rochester, School of Medicine and Dentistry, Rochester, NY, 14642, USA. Electronic address:

While extensive research has demonstrated an interdependent role of osteogenesis and angiogenesis in bone tissue engineering, little is known about how functional blood vessel networks are organized to initiate and facilitate bone tissue regeneration. Building upon the success of a biomimetic composite nanofibrous construct capable of supporting donor progenitor cell-dependent regeneration, we examined the angiogenic response and spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of cranial bone defect repair utilizing high resolution multiphoton laser scanning microscopy (MPLSM) in conjunction with intravital imaging. We demonstrate here that the regenerative vasculature can be specified as arterial and venous capillary vessels based upon endothelial surface markers of CD31 and Endomucin (EMCN), with CD31EMCN vessels exhibiting higher flowrate and higher oxygen tension (pO) than CD31EMCN vessels. Read More

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September 2021

Fabrication of Paper Sheets Coatings Based on Chitosan/Bacterial Nanocellulose/ZnO with Enhanced Antibacterial and Mechanical Properties.

Int J Mol Sci 2021 Jul 9;22(14). Epub 2021 Jul 9.

Department of Nanomaterials Physicochemistry, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastow Ave. 49, 71-065 Szczecin, Poland.

Here, we designed paper sheets coated with chitosan, bacterial cellulose (nanofibers), and ZnO with boosted antibacterial and mechanical activity. We investigated the compositions, with ZnO exhibiting two different sizes/shapes: (1) rods and (2) irregular sphere-like particles. The proposed processing of bacterial cellulose resulted in the formation of nanofibers. Read More

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Conductive polypyrrole-encapsulated silk fibroin fibers for cardiac tissue engineering.

Biomaterials 2021 09 7;276:121008. Epub 2021 Jul 7.

National University of Singapore, Department of Biomedical Engineering, 4 ENGINEERING DR 3, #04-08, 117583, Singapore; National University of Singapore, Life Sciences Institute, Tissue Engineering Programme, DSO (Kent Ridge) Building, 27 Medical Drive, #04-01, 117510, Singapore. Electronic address:

Polypyrrole (PPy) has been utilized in smart scaffolds to improve the functionality of the engineered cardiac tissue. Compared to the commonly used aqueous coating, here, PPy was blended into silk fibroin (SF) solution to electrospin conductive PPy-encapsulated SF nanofibers. Combinations of various SF concentrations (5%, 7%, and 12%) and different PPy-to-SF ratios (15:85, 30:70, and 40:60) were compared. Read More

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September 2021

Seaweed-Derived Alginate-Cellulose Nanofiber Aerogel for Insulation Applications.

ACS Appl Mater Interfaces 2021 Jul 13;13(29):34899-34909. Epub 2021 Jul 13.

Division of Materials Science, Luleå University of Technology, SE 971 87 Luleå, Sweden.

The next generation of green insulation materials is being developed to provide safer and more sustainable alternatives to conventional materials. Bio-based cellulose nanofiber (CNF) aerogels offer excellent thermal insulation properties; however, their high flammability restricts their application. In this study, the design concept for the development of a multifunctional and non-toxic insulation material is inspired by the natural composition of seaweed, comprising both alginate and cellulose. Read More

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Functionalized Prion-Inspired Amyloids for Biosensor Applications.

Biomacromolecules 2021 07 1;22(7):2822-2833. Epub 2021 Jul 1.

Institut de Biotecnologia i de Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, 08193 Bellaterra (Barcelona), Spain.

Protein amyloid nanofibers provide a biocompatible platform for the development of functional nanomaterials. However, the functionalities generated up to date are still limited. Typical building blocks correspond to aggregation-prone proteins and peptides, which must be modified by complex and expensive reactions post-assembly. Read More

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Nicotinamide-based supergelator self-assembling via asymmetric hydrogen bonding NH⋯OC and H⋯Br pattern for reusable, moldable and self-healable nontoxic fuel gels.

J Colloid Interface Sci 2021 Dec 15;603:182-190. Epub 2021 Jun 15.

Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, SK-83104 Bratislava, Slovakia. Electronic address:

Hypothesis: Development of highly efficient low-molecular weight gelators (LMWGs) for safe energy storage materials is of great demand. Energy storage materials as fuel gels are often achieved by construction of hybrid organic frameworks capable of multiple noncovalent interactions in self-assembly, which allow tuning required properties at the molecular level by altering individual building blocks of the LMWG. However, LMWGs have limited rechargeable capability due to their chemical instability. Read More

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December 2021

Deciphering the evolution of supramolecular nanofibers in solution and solid-state: a combined microscopic and spectroscopic approach.

Chem Sci 2021 Mar 18;12(16):5874-5882. Epub 2021 Mar 18.

Department of Chemistry, Indian Institute of Science Education and Research Bhopal Bhopal By-Pass Road, Bhauri Bhopal 462066 Madhya Pradesh India

Supramolecular self-assembly of small organic molecules has emerged as a powerful tool to construct well-defined micro- and nanoarchitecture through fine-tuning a range of intermolecular interactions. The size, shape, and optical properties of these nanostructures largely depend on the specific assembly of the molecular building units, temperature and polarity of the medium, and external stimuli. The engineering of supramolecular self-assembled nanostructures with morphology-dependent tunable emission is in high demand due to the promising scope in nanodevices and molecular machines. Read More

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De novo design of a pH-triggered self-assembled β-hairpin nanopeptide with the dual biological functions for antibacterial and entrapment.

J Nanobiotechnology 2021 Jun 14;19(1):183. Epub 2021 Jun 14.

Laboratory of Molecular Nutrition and Immunity, The Institute of Animal Nutrition, Northeast Agricultural University, Harbin, People's Republic of China.

Background: Acid-tolerant enteric pathogens can evade small intestinal acid barriers, colonize and infect the intestinal tract. However, broad-spectrum antibiotics are not the best therapeutic strategy because of the disruption of intestinal flora caused by its indiscriminate antimicrobial activity against beneficial and harmful bacteria. So that is what inspired us to combine pH regulation with nanotechnology to develop a pH-triggered site-targeted antimicrobial peptide with entrapping function. Read More

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Novel photosensitive dual-anisotropic conductive Janus film endued with magnetic-luminescent properties and derivative 3D structures.

J Colloid Interface Sci 2021 Nov 26;601:899-914. Epub 2021 May 26.

Key Laboratory of Applied Chemistry and Nanotechnology at Universities of Jilin Province, Changchun University of Science and Technology, Changchun 130022, China.

A new photosensitive dual-anisotropic conductive Janus film (PDCJF) is proposed for the first time. It is rationally designed and manufactured by facile electrospinning. PDCJF is firstly constructed using 2,7-dibromo-9-fluorenone (DBF) with photoconductive and luminescent properties. Read More

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November 2021

Intravenous Delivery of Lung-Targeted Nanofibers for Pulmonary Hypertension in Mice.

Adv Healthc Mater 2021 07 1;10(13):e2100302. Epub 2021 Jun 1.

Department of Surgery, University of North Carolina, 4041 Burnett Womack, 101 Manning Drive, Chapel Hill, NC, 27599, USA.

Pulmonary hypertension is a highly morbid disease with no cure. Available treatments are limited by systemic adverse effects due to non-specific biodistribution. Self-assembled peptide amphiphile (PA) nanofibers are biocompatible nanomaterials that can be modified to recognize specific biological markers to provide targeted drug delivery and reduce off-target toxicity. Read More

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In vitro and in vivo biological assessment of dual drug-loaded coaxial nanofibers for the treatment of corneal abrasion.

Int J Pharm 2021 Jul 24;604:120732. Epub 2021 May 24.

Medway School of Pharmacy, The Universities of Greenwich and Kent at Medway, Anson Building Central Avenue, Chatham, Kent, ME4 4TB, United Kingdom.

The treatment of corneal abrasion currently involves the topical administration of antibiotics, with moxifloxacin HCl (0.5% w/v) eye drops being one of the most widely used treatments. Our previous work (Tawfik et al. Read More

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Nanofibers Produced by Electrospinning of Ultrarigid Polymer Rods Made from Designed Peptide Bundlemers.

ACS Appl Mater Interfaces 2021 Jun 24;13(22):26339-26351. Epub 2021 May 24.

Department of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.

Mimicking the hierarchical assembly of natural fiber materials is an important design challenge in the manufacturing of nanostructured materials with biomolecules such as peptides. Here, we produce nanofibers with control of structure over multiple length scales, ranging from peptide molecule assembly into supramolecular building blocks called "bundlemers," to rigid-rod formation through a covalent connection of bundlemer building blocks, and, ultimately, to uniaxially oriented fibers made with the rigid-rod polymers. The peptides are designed to physically assemble into coiled-coil bundles, or bundlemers, and to covalently interact in an end-to-end fashion to produce the rigid-rod polymer. Read More

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Core-Shell Structured Antimicrobial Nanofiber Dressings Containing Herbal Extract and Antibiotics Combination for the Prevention of Biofilms and Promotion of Cutaneous Wound Healing.

ACS Appl Mater Interfaces 2021 Jun 23;13(21):24356-24369. Epub 2021 May 23.

Center for Environmental Nuclear Research, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu 603203, India.

Burn wounds are susceptible to microbial invasion from both resident and exogenous bacteria, which becomes a critical public health issue and causes substantial economic burden. There is a perceived demand to produce new antimicrobial wound dressings that hinder bacterial colonization while accelerating the healing process and hence would provide an improved standard of care for patients. Since ancient times, herbal extracts from medicinally important plants have extensively been used for treating burn injuries. Read More

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In situ loading MnO onto 3D Aramid nanofiber aerogel as High-Performance lead adsorbent.

J Colloid Interface Sci 2021 Oct 12;600:403-411. Epub 2021 May 12.

State Key Laboratory of Separation Membranes and Membrane Processes/National Center for International Joint Research on Separation Membranes, Tiangong University, Tianjin 300387, PR China; School of Textile Science and Engineering, Tiangong University, Tianjin 300387, PR China. Electronic address:

Fabricating a high-performance adsorbent as a desirable candidate for removing Pb from aqueous water remains a challenge. Aramid nanofibers (ANFs) are promising building blocks that have realized multifunctional applications due to their intrinsic mechanical and chemical stability. Herein, an in situ loading strategy for preparing nanofiber composite aerogel was proposed by assembling ANFs into a 3D aerogel and applying it as host media for the in situ polymerization of pyrrole followed by facile redox reaction between the polypyrrole (PPy) and MnO to load manganese dioxide (MnO). Read More

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October 2021

International Scientific Collaboration Is Needed to Bridge Science to Society: USERN2020 Consensus Statement.

SN Compr Clin Med 2021 May 11:1-5. Epub 2021 May 11.


Scientific collaboration has been a critical aspect of the development of all fields of science, particularly clinical medicine. It is well understood that myriads of benefits can be yielded by interdisciplinary and international collaboration. For instance, our rapidly growing knowledge on COVID-19 and vaccine development could not be attained without expanded collaborative activities. Read More

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Studies on the electrostatic effects of stretched PVDF films and nanofibers.

Nanoscale Res Lett 2021 May 3;16(1):79. Epub 2021 May 3.

Sino-Danish Center for Education and Research (SDC), Interdisciplinary Nanoscience Center (iNANO), Aarhus University, DK-8000, Aarhus C, Denmark.

The electroactive β-phase in Poly (vinylidene fluoride, PVDF) is the most desirable conformation due to its highest pyro- and piezoelectric properties, which make it feasible to be used as flexible sensors, wearable electronics, and energy harvesters etc. In this study, we successfully developed a method to obtain high-content β-phase PVDF films and nanofiber meshes by mechanical stretching and electric spinning. The phase transition process and pyro- and piezoelectric effects of stretched films and nanofiber meshes were characterized by monitoring the polarized light microscopy (PLM) images, outputting currents and open-circuit voltages respectively, which were proved to be closely related to stretching ratio (λ) and concentrations. Read More

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Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications.

Nanomaterials (Basel) 2021 Apr 6;11(4). Epub 2021 Apr 6.

Department of Mechanical Engineering, Center for Nanofibers and Nanotechnology, National University of Singapore, Singapore 119260, Singapore.

Shape memory polymers (SMPs) as a relatively new class of smart materials have gained increasing attention in academic research and industrial developments (e.g., biomedical engineering, aerospace, robotics, automotive industries, and smart textiles). Read More

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Tuning the Structure of Nylon 6,6 Electrospun Bundles to Mimic the Mechanical Performance of Tendon Fascicles.

Front Bioeng Biotechnol 2021 6;9:626433. Epub 2021 Apr 6.

Department of Industrial Engineering, Alma Mater Studiorum-Università di Bologna, Bologna, Italy.

Tendon and ligament injuries are triggered by mechanical loading, but the specific mechanisms are not yet clearly identified. It is well established however, that the inflection and transition points in tendon stress-strain curves represent thresholds that may signal the onset of irreversible fibrillar sliding. This phenomenon often results in a progressive macroscopic failure of these tissues. Read More

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Novel humidity sensors based on nanomodified Portland cement.

Sci Rep 2021 Apr 14;11(1):8189. Epub 2021 Apr 14.

Building Materials, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 97187, Luleå, Sweden.

Commonly used humidity sensors are based on metal oxides, polymers or carbon. Their sensing accuracy often deteriorates with time, especially when exposed to higher temperatures or very high humidity. An alternative solution based on the utilization of Portland cement-based mortars containing in-situ grown carbon nanofibers (CNFs) was evaluated in this study. Read More

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Fragile-Tough Mechanical Reversion of Silk Materials via Tuning Supramolecular Assembly.

ACS Biomater Sci Eng 2021 06 9;7(6):2337-2345. Epub 2021 Apr 9.

Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United States.

Regenerated silk nanofibers are interesting as protein-based material building blocks due to their unique structure and biological origin. Here, a new strategy based on control of supramolecular assembly was developed to regulate interactions among silk nanofibers by changing the solvent, achieving tough mechanical features for silk films. Formic acid was used to replace water related to charge repulsion of silk nanofibers in solution, inducing interactions among the nanofibers. Read More

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Recycling of High-Value-Added Aramid Nanofibers from Waste Aramid Resources via a Feasible and Cost-Effective Approach.

ACS Nano 2021 Apr 22;15(4):7195-7207. Epub 2021 Mar 22.

College of Bioresources Chemical and Materials Engineering, National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi Province Key Laboratory of papermaking Technology and Specialty paper Development, Shaanxi University of Science & Technology, No. 6, Xuefu Road, Xi'an 710021, China.

High-performance aramid fibers are extensively applied in the civil and military fields. A great deal of waste aramid resources originating from the manufacturing process, spare parts, or end of life cycle are wrongly disposed (, landfill, smash, fibrillation), causing a waste of valuable resources as well as severe environmental pollution. Although aramid nanofibers (ANFs) have recently been recently reported as one of the most promising building blocks due to their excellent properties, they suffer from an extremely high production expenditure, thereby greatly hindering their scale-up application. Read More

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Biopolymer Nanofibers for Nanogenerator Development.

Research (Wash D C) 2021 22;2021:1843061. Epub 2021 Feb 22.

Key Laboratory of Bio-Based Material Science and Technology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.

The development of nanogenerators (NGs) with optimal performances and functionalities requires more novel materials. Over the past decade, biopolymer nanofibers (BPNFs) have become critical sustainable building blocks in energy-related fields because they have distinctive nanostructures and properties and can be obtained from abundant and renewable resources. This review summarizes recent advances in the use of BPNFs for NG development. Read More

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February 2021

Breathable Nanogenerators for an On-Plant Self-Powered Sustainable Agriculture System.

ACS Nano 2021 03 9;15(3):5307-5315. Epub 2021 Mar 9.

School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.

Building an intelligent interface between plants and the environment is of paramount importance for real-time monitoring of the health status of plants, especially promising for high agricultural yield. Although the advancement of various sensors allows automated monitoring, developing a sustainable power supply for these electronic devices remains a formidable challenge. Herein, a waterproof and breathable triboelectric nanogenerator (WB-TENG) is designed based on poly(vinylidene fluoride--hexafluoropropylene) (PVDF-HFP) nanofibers embedded with fluorinated carbon nanotubes (F-CNT) microspheres, which was realized by simultaneous electrospinning and electrospraying, respectively. Read More

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