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BMC Plant Biol 2021 Mar 24;21(1):150. Epub 2021 Mar 24.

Anhui Province Key Laboratory of Farmland Ecological Conservation and Pollution Prevention, School of Resources and Environment, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, P.R. China.

Background: Rice is particularly effective, compared to other cereals, at accumulating arsenic (As), a nonthreshold, class 1 human carcinogen in shoot and grain. Nano-zinc oxide is gradually used in agricultural production due to its adsorption capacity and as a nutrient element. An experiment was performed to explore the effects of zinc oxide nanoparticles (nZnO) on arsenic (As) toxicity and bioaccumulation in rice. Read More

Biol Trace Elem Res 2021 Feb 12. Epub 2021 Feb 12.

Department of Poultry Science, College of Veterinary Science, P.V. Narsimha Rao Telangana Veterinary University, Rajendranagar, Hyderabad, Telangana, India.

An experiment was conducted to evaluate the effect of supplementation of zinc in the diet in the form of nano zinc oxide (nano ZnO) on the performance of broilers. A total of 240 day-old commercial broiler chicks were distributed in a completely randomized design into 6 treatments with 8 replicates of 5 chicks each. Treatments comprised of T- basal diet (BD) without ZnO supplementation, T- 2. Read More

Int J Prosthodont 2021 Jan-Feb;34(1):54-60

Purpose: To evaluate the physical and mechanical properties of maxillofacial silicone elastomers following the incorporation of a specific particle size and concentration of nano-titanium dioxide (TiO) and nano-zinc oxide (ZnO).

Materials And Methods: Nano-TiO and nano-ZnO of 20-nm and 40-nm particle sizes and in 1% and 2% concentrations were chosen. Silicone elastomer samples were prepared according to the manufacturer's recommendations. Read More

J Dent (Shiraz) 2020 Dec;21(4):307-313

Dept. of Dental Material, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Statement Of The Problem: Some patients may report moderate-to-severe pain and/or swelling following root canal treatment, which is undesirable for both the patient and dentist and may require an unscheduled emergency visit by patients to relieve their symptoms.

Purpose: The aim of this study was to evaluate the post-treatment flare-up incidence following application of nano zinc oxide-eugenol (NZOE) sealer in mandibular first molars with irreversible pulpitis.

Materials And Method: This single-blinded study was performed on 60 patients having mandibular first molars with irreversible pulpitis. Read More

Dent Mater 2021 Mar 17;37(3):e182-e193. Epub 2020 Dec 17.

Ph.D. Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA; Operative Dentistry Division, General Dentistry Department University of Maryland School of Dentistry, Baltimore, MD 21201, USA. Electronic address:

Objective: Various nanoparticles are currently under investigation to impart biointeractivity for dental materials. This study aimed to: (1) formulate an experimental dental adhesive containing ZnO nanoparticles; (2) evaluate its chemical and mechanical properties; and (3) assess the antibacterial response against oral microcosm biofilm.

Methods: Nanosized ZnO was chemically and morphologically evaluated. Read More

Dis Aquat Organ 2020 Dec 17;142:147-160. Epub 2020 Dec 17.

Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Zagazig University, PO Box 44519, Zagazig 4511, Sharkia, Egypt.

Zinc (Zn) is an important trace element in fish diets that is required for growth, immunity and antioxidant defense mechanisms. The current study assessed the effects of both organic and nanoparticle zinc oxide (ZnO and ZnO-NPs, respectively) on growth performance, immune response and the antimicrobial effect against Pseudomonas aeruginosa in African catfish Clarias gariepinus. Fish were fed either a control diet or diets supplemented with organic ZnO at concentrations of 20 and 30 mg kg-1 or ZnO-NPs at concentrations of 20 and 30 mg kg-1. Read More

Int J Mol Sci 2020 Nov 22;21(22). Epub 2020 Nov 22.

Department of Physics, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China.

This article reviews the recent developments in the synthesis, antibacterial activity, and visible-light photocatalytic bacterial inactivation of nano-zinc oxide. Polycrystalline wurtzite ZnO nanostructures with a hexagonal lattice having different shapes can be synthesized by means of vapor-, liquid-, and solid-phase processing techniques. Among these, ZnO hierarchical nanostructures prepared from the liquid phase route are commonly used for antimicrobial activity. Read More

Animals (Basel) 2020 Nov 27;10(12). Epub 2020 Nov 27.

Department of Biology, College of Science, King Khalid University, Abha 61413, Saudi Arabia.

The present study aimed to determine the effects of zinc oxide nanoparticles (ZnO-NPs), thyme oil (THO), or their combination on the nutrient digestibility coefficients, reproductive parameters, and some blood metabolites of male Californian rabbits. One hundred rabbits, 29-weeks of age (initial body weight 3.48 ± 0. Read More

Environ Sci Pollut Res Int 2021 Feb 21;28(5):5158-5167. Epub 2020 Sep 21.

Department of Pathology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62515, Egypt.

Zinc is an essential nutritional trace mineral required for growth and health. The aim of the current work is to compare the effects of bulk zinc oxide and zinc oxide nanoparticles (ZnO-NPs) on the growth performance, feeding behavior, and zinc residues in tissues with the associated histopathological alterations in chicken. Meanwhile, the antibacterial activity against the isolated E. Read More

Eur J Dent 2020 Oct 8;14(4):525-532. Epub 2020 Sep 8.

Department of Prosthetic Dentistry, Faculty of Dentistry, Prince of Songkla University, Songkhla, Thailand.

Objective:  This article aimed to study the effect of different concentrations of nano zinc oxide particles on the color change of MDX4-4210 facial silicone elastomer after artificial aging.

Materials And Methods:  Silicone specimens ( = 150) were fabricated by incorporating intrinsic pigments and divided into three groups-white, yellow, and red, each group consisting of 50 specimens ( = 50). In each color, specimens were subdivided into five subgroups according to the quantity of zinc oxide nanoparticles (0, 0. Read More

Animals (Basel) 2020 Aug 24;10(9). Epub 2020 Aug 24.

School of Animal, Rural and Environmental Sciences, Nottingham Trent University, Nottingham NG25 0QF, UK.

Recently, nanotechnology has been widely adopted in many fields. The goal of this study was to evaluate the potential for amino acid coated nano minerals as a supplement in broiler feed. Zinc was selected as a model mineral for this test and supplementation of nano zinc, both coated and uncoated was compared with organic and inorganic commercial forms of zinc. Read More

J Sci Food Agric 2021 Jan 23;101(2):735-745. Epub 2020 Sep 23.

National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Key Laboratory of Agro-ecological Processes in Subtropical Region, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Breeding of Livestock and Poultry, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China.

Background: Coated nano zinc oxide (Cnz) is a new feed or food additive, which is a potential replacement for a pharmacological dose level of ZnO. This study evaluated the positive effects of different concentrations of Cnz on the intestinal bacterial core, enterobacterial composition and mucosal barrier function in a pig model.

Results: Microbiota sequencing results showed that Cnz could significantly alter the intestinal microbiota composition and metabolism. Read More

J Environ Manage 2020 Oct 12;272:111048. Epub 2020 Jul 12.

Department of Chemistry, University of Arkansas at Little Rock, Little Rock, AR, 72204, USA. Electronic address:

Phosphate is one of the most costly and complex environmental pollutants that leads to eutrophication, which decreases water quality and access to clean water. Among different adsorbents, biochar is one of the promising adsorbents for phosphate removal as well as heavy metal removal from an aqueous solution. In this study, biochar was impregnated with nano zinc oxide in the presence of glycine betaine. Read More

Nanomaterials (Basel) 2020 Jul 5;10(7). Epub 2020 Jul 5.

Department of Chemical Engineering, Granada University, 18071 Granada, Spain.

Zinc Oxide is widely used in many industrial sectors, ranging from photocatalysis, rubber, ceramic, medicine, and pigment, to food and cream additive. The global market is estimated to be USD 3600M yearly, with a global production of 10 Mt. In novel applications, size and shape may sensibly increase the efficiency and a new nano-ZnO market is taking the lead (USD 2000M yearly with a capacity of 1 Mt and an expected Compound Annual Growth Rate of 20%/year). Read More

Int J Biol Macromol 2020 Sep 16;159:793-803. Epub 2020 May 16.

School of Materials Science and Engineering, Zhengzhou University, Zhengzhou, Henan 450001, China. Electronic address:

Nanocomposite films of soluble soybean polysaccharide (SSPS)/nano zinc oxide (nZnO) reinforced with microfibrillated cellulose (MFC) were developed by solvent casting method. The structure, optical, barrier, thermal, surface wettability, mechanical properties and antimicrobial activity of the SSPS/MFC, SSPS/nZnO and SSPS/nZnO/MFC nanocomposite films were evaluated. Attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectra indicated interactions between SSPS and the nano-fillers. Read More

J Pak Med Assoc 2020 May;70(5):830-834

ACRC-Polymer and Plastic Section, PCSIR labs complex, Karachi, Pakistan.

Objective: To investigate the dimensional stability of dental amalgam after the incorporation of zinc oxide nano powder.

Methods: The experimental study was conducted at the Hamdard University Dental Hospital and the Pakistan Council of Scientific and Industrial Research laboratories, Karachi, from January to June, 2018. Direct precipitation method was used in which analytical grade sodium hydroxide and zinc nitrate hex hydrate were used without any further purification. Read More

Polymers (Basel) 2020 May 2;12(5). Epub 2020 May 2.

Institute of Textile Materials and Polymer Composites, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.

Active dressings based on natural polymers are becoming increasingly popular on the market. One of such polymers is alginate, which is characterized by biodegradability, resorbability, has no carcinogenic properties, does not have allergenic or hemostatic properties, and has a confirmed lack of toxicity. However, this polymer does not show biocidal and biostatic properties, therefore the purpose of this research was to select the appropriate conditions for the production of calcium alginate fibers modified with nano titanium dioxide and nano zinc oxide. Read More

Pak J Biol Sci 2020 Mar;23(4):478-490

Background And Objective: Saline soils are restrictive factors to agriculture in arid and semi-arid regions, plant growth and productivity. Thus, it was important to consider how, nano-zinc oxide or bulk zinc oxide alleviates the oxidative salt stress in the presence of Arbuscular mycorrhiza (AM) fungi by two wheat cultivars (Sids 13 and Sakha 94).

Materials And Methods: A field experiment was carried out during two winter successive seasons to study the beneficial role of nano-zinc oxide or bulk zinc oxide with different concentrations (5 and 10 mg L-1) in enhancing growth, some biochemical and physiological of two wheat cultivars under saline soil. Read More

J Dermatolog Treat 2020 Apr 23:1-8. Epub 2020 Apr 23.

Chemical Engineering Department, School of Industrial Engineering - Módulo Tecnológico Industrial (MTI), University of Vigo, Vigo, Spain.

This is a novel work that includes the use of a biosurfactant extract obtained from corn milling industry (named BS-CSW), with antimicrobial activity, as ingredient in formulations to treat acne vulgaris. With this purpose, it was established an incomplete experimental design with 3 independent variables, based on the concentration of non-nano zinc oxide (ZnO) (0-2%), BS-CSW (0-5%) and salicylic acid (0-2%). This design allowed to obtain a theoretical model that calculates the inhibitory effect on (also named ) for any formulation carried with the ingredients appointed before. Read More

Mar Pollut Bull 2020 Apr 20;153:110973. Epub 2020 Feb 20.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China; State Key Laboratory of Marine Pollution (City University of Hong Kong), Tat Chee Avenue, Kowloon, Hong Kong, China. Electronic address:

This study compared in vivo acute toxicities of nine engineered nano metal oxides to the marine diatom Skeletonema costatum and rotifer Brachionus koreanus. The sequence of their toxicities to S. costatum, based on growth inhibition, was: nano zinc oxide (nZnO) > nTiO (rutile) > nMgO > Annealed nMgO > nTiO (anatase) > γ-nAlO > nInO > α-nAlO > nSnO. Read More

Molecules 2020 Mar 13;25(6). Epub 2020 Mar 13.

Institute of Agriculture and Food Engineering, Kunming University of Science and Technology, Kunming 650550, China.

This study aimed to reinforce the barrier performance (i.e., oxygen-gas and water-vapor permeability) of poly(lactic acid) (PLA)-based films. Read More

Front Microbiol 2020 26;11:267. Epub 2020 Feb 26.

Environment and Climate Change Canada, Saskatoon, SK, Canada.

Manufactured Zn oxide nanoparticle (ZnO-NP) are extensively used world-wide in personal care and industrial products and are important contaminants of aquatic environments. To understand the overall impact of ZnO-NP contamination on aquatic ecosystems, investigation of their toxicity on aquatic biofilms is of particular consequence, given biofilms are known sinks for NP contaminants. In order to assess alterations in the functional activity of river microbial biofilm communities as a result of environmentally-relevant ZnO-NP exposure, biofilms were exposed to ionic zinc salt or ZnOPs that were uncoated (hydrophilic), coated with silane (hydrophobic) or stearic acid (lipophilic), at a total concentration of 188 μg l Zn. Read More

Eur J Dent 2020 Feb 13;14(1):45-54. Epub 2020 Mar 13.

Department of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Objectives:  Dentin hypersensitivity (DH) is mainly due to the loss and replenishment of minerals from tooth structure, where the lost minerals can be rehabilitated with a biomimetic approach. The objectives were to determine the relative dentin abrasivity (RDA) of experimental (EXT) dentifrices and to determine the efficacy to occlude dentinal tubules.

Materials And Methods:  Experimental dentifrices contained nano-fluoridated bioactive glass (n-FBG: 1. Read More

Vet World 2020 Jan 16;13(1):121-126. Epub 2020 Jan 16.

Department of Animal Husbandry, School of Agriculture and Animal Sciences, Gandhigram Rural Institute, Dindigul, Tamil Nadu, India.

Aim: This study was aimed to investigate antimicrobial and cytotoxicity effect of nano ZnO in for the application of livestock feed supplement.

Materials And Methods: Nano ZnO was synthesized by wet chemical precipitation method using zinc acetate as a precursor and sodium hydroxide was used for reducing the precursor salt. The properties of synthesized powder were characterized using ultraviolet (UV)-visible spectroscopy, Fourier transform infrared (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD), respectively. Read More

Nanomaterials (Basel) 2020 Feb 2;10(2). Epub 2020 Feb 2.

State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.

ZnO NPs have been assessed to show adverse effects on reproductive organs, but the molecular mechanisms of reproductive toxicity have not been sufficiently studied. In this research, the dosage effects from the oral exposure of ZnO NPs (30 nm) to pregnant mice in gestation day 10.5 to 17. Read More

Int J Nanomedicine 2020 6;15:1-15. Epub 2020 Jan 6.

Department of Plastic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing 400038, People's Republic of China.

Background: Developing an ideal wound dressing that meets the multiple demands of safe and practical, good biocompatibility, superior mechanical property and excellent antibacterial activity is highly desirable for wound healing. Bacterial cellulose (BC) is one of such promising class of biopolymers since it can control wound exudates and can provide moist environment to a wound resulting in better wound healing. However, the lack of antibacterial activity has limited its application. Read More

Eur J Dent 2020 Feb 4;14(1):38-44. Epub 2020 Feb 4.

Department of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Objectives:  The objectives were to measure fluoride release and assess the antimicrobial behavior of fluoride-doped nano bioactive glass (F-nBG) and nano zinc oxide (ZnO)-enriched novel dentifrices.

Materials And Methods:  Experimental dentifrices were synthesized by incorporating ZnO nanoparticles and F-nBG (1.5 wt% and 4 wt%) as active ingredients. Read More

Ecotoxicology 2020 Mar 15;29(2):175-184. Epub 2020 Jan 15.

Evolutionary Stress Ecology and Ecotoxicology, KU Leuven, Leuven, 3000, Belgium.

A key challenge for ecological risk assessment of contaminants under global warming is to predict effects at higher levels of biological organisation. One approach to reach this goal is to study how contaminants and warming cause changes in body stoichiometry as these may potentially cascade through food webs. Furthermore, though contaminants typically interact with warming, how rapid adaptation to higher temperatures affects these interactions is poorly studied. Read More

Int J Nanomedicine 2019 20;14:7729-7741. Epub 2019 Sep 20.

Department of Biochemistry, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

Background: Recently, several studies demonstrate the possible role of zinc oxide (ZnO) in the protection of several skin diseases, but less is known about the role of ZnO nanoparticles in the inflammatory skin disease. So, this study was designed to confirm the pivotal role of the nano zinc oxide cream in the alleviation of lead oxide (PbO) induced-allergic dermatitis in rats.

Materials And Methods: Two concentrations (1% and 6%) of ZnONPs creams were prepared and characterized prior to being used in the study. Read More

Front Dent 2019 Mar-Apr;16(2):105-112. Epub 2019 Apr 30.

Private Practice, Yazd, Iran.

Objectives: The purpose of the present study was to evaluate the antimicrobial effect of various sizes and concentrations of zinc oxide (ZnO) nanoparticles on (), (), (), and ().

Materials And Methods: Solutions at the concentration of 10 μg/ml were prepared using 20-nm, 40-nm, and 140-nm nano ZnO (nZnO) powder. The antimicrobial effect of nZnO was determined using the disk diffusion method. Read More