Search Our Scientific Publications & Authors

Cutis 2022 Jun;109(6):310-313

Department of Dermatology, Naval Readiness and Training Command San Diego, California.

It is well established that many common skin diseases may result in mild to severe cosmetic disfigurement. Similarly, patients with these conditions have an increased risk for depression, anxiety, feelings of stigmatization, and self-harm ideation. There also is an increased risk for hospitalizations for mental health in patients with acne, rosacea, and hidradenitis suppurativa (HS). Read More

J Orthop 2022 Sep-Oct;33:105-111. Epub 2022 Jul 31.

The University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH, 43614, USA.

Background: Interprosthetic femur fractures (IFFs) are rare, but the treatment is challenging. Currently, there are many treatment methods used in practice, but an updated systematic review of comparison of common different surgical outcomes has not been thoroughly inspected.

Methods: A systematic review of retrospective studies was conducted. Read More

Evid Based Complement Alternat Med 2022 31;2022:5020960. Epub 2022 Jul 31.

Department of Orthopedics, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, China.

To analyze the treatment of elderly femoral intertrochanteric fracture (EFIF) using InterTan intramedullary nail (InterTanIN) and proximal femoral nail antirotation (PFNA). A total of 75 patients suffering from EFIF receiving intramedullary fixation were retrospectively collected. According to intramedullary fixation methods, the patients were separated into InterTanIN group and PFNA group. Read More

Am J Transl Res 2022 15;14(7):4795-4803. Epub 2022 Jul 15.

Department of Orthopedics, Taizhou Hospital of Traditional Chinese Medicine Taizhou, Zhejiang, China.

Objective: To compare the differences between proximal femoral nail antirotation (PFNA) and dynamic hip screw (DHS) in treatment of femoral trochanteric fracture and analyze the factors influencing recovery after PFNA treatment.

Methods: Eighty-six patients with femoral trochanteric fracture admitted to Taizhou Hospital of Traditional Chinese Medicine between January 2019 and June 2021 were enrolled in the study and assigned into a PFNA group and DHS group (n=43 in each group) before undergoing these treatments. The clinical efficacy, inflammatory factors, and myocardial injury markers were compared between the two groups. Read More

Front Pediatr 2022 26;10:894262. Epub 2022 Jul 26.

Department of Orthopaedic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: The management strategy of subtrochanteric fractures remains controversial, and triple elastic stable intramedullary nail (ESIN) has not been reported for pediatric subtrochanteric fractures. This study aimed to compare the clinical effects of treating school-aged children with subtrochanteric fractures with triple ESINs versus locking plates.

Methods: We conducted a retrospective review of pediatric patients with subtrochanteric femoral fracture receiving either triple ESINs (TE) or locking plates (LPs) between January 2010 and January 2018. Read More

Sudan J Paediatr 2022 ;22(1):119-120

Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, India.

Clin Case Rep 2022 Aug 8;10(8):e6191. Epub 2022 Aug 8.

Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

The lichen planus (LP) is an inflammatory and immune-mediated disorder that can affect the hair, mucous membranes, nails, and skin. Lichen planus rarely affects the lips. In cases of lip involvement, it presents as radiated streaks, lace-like papules, and erosions. Read More

Polymers (Basel) 2022 Jul 31;14(15). Epub 2022 Jul 31.

Department of Wood and Paper Science and Technology, College of Natural Resources, University of Tehran, Karaj 14179-35840, Iran.

Cross-laminated timber (CLT) can be used as an element in various parts of timber structures, such as bridges. Fast-growing hardwood species, like poplar, are useful in regions where there is a lack of wood resources. In this study, the withdrawal resistance of nine types of conventional fasteners (stainless-steel nails, concrete nails and screws, drywall screws, three types of partially and fully threaded wood screws, and two types of lag screws), with three loading directions (parallel to the grain, perpendicular to the surface, and tangential), and two layer arrangements (0-90-0° and 0-45-0°) in 3-ply CLTs made of poplar as a fast-growing species and fir as a common species in manufacturing of CLT was investigated. Read More

J Clin Med 2022 Jul 31;11(15). Epub 2022 Jul 31.

Department of Trauma-, Hand-, and Reconstructive Surgery, Ulm University, Albert-Einstein-Allee 23, 89081 Ulm, Germany.

Background: Forearm fractures are one of the most common fractures in children. Over the last years, a tendency towards surgical treatment was seen, especially closed reduction and internal fixation with elastic stable internal nailing (ESIN). Despite an overall low complication rate being described, a risk of intraoperative complications remains. Read More

Adv Clin Chem 2022 5;109:165-183. Epub 2022 May 5.

Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, United States. Electronic address:

Biotin (vitamin B or vitamin H), a member of vitamin B complex, acts as a cofactor for five biotin-dependent carboxylases, thus playing critical roles in gluconeogenesis, fatty acid synthesis and amino acid catabolism. Although rare inborn errors of metabolism may cause biotin deficiency, these can be successfully treated with biotin supplementation. In general, normal individuals do not get any benefit from taking biotin supplement. Read More

Eur J Med Genet 2022 Aug 8:104580. Epub 2022 Aug 8.

Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan. Electronic address:

Kagami-Ogata syndrome (KOS) is an imprinting disorder characterized by polyhydramnios, bell-shaped thorax with coat-hanger appearance (curved ribs), respiratory distress, abdominal wall defects, and distinct facial features, together with intellectual developmental delay with special needs. Abnormal expression of the imprinted genes on chromosome 14q32.2 causes KOS. Read More

Dermatitis 2022 Aug 12. Epub 2022 Aug 12.

From the Department of Dermatology, National Taiwan University Hospital, Taipei.

Abstract: Friction is unavoidable in activites of daily life and is associated with various dermatological disorders. A comprehensive literature review showed friction can induce epidermal changes, dermatitis, alteration of the dermis, diseases of abnormal deposition, alteration of the hair and follicles, nail diseases, pigmentary disorders, and skin tumors. Cultural, religious, and occupational factors may predispose to the development friction-related skin disorders. Read More

Cureus 2022 Jul 7;14(7):e26652. Epub 2022 Jul 7.

Trauma and Orthopaedics, Queen Elizabeth Hospital Birmingham, Birmingham, GBR.

Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder with a clinical triad of capillary malformations, vascular abnormalities, and bone/soft tissue hypertrophy. This is the first case of closed femoral shaft fracture in a patient with KTS managed by flexible intramedullary nails. A 34-year-old patient sustained a right femoral mid-shaft spiral fracture after slipping on the grass. Read More

Cureus 2022 Jul 27;14(7):e27328. Epub 2022 Jul 27.

Trauma and Orthopaedics, The Western Trust Health and Social Care (Northern Ireland), Londonderry, GBR.

Background Hip fracture is a debilitating injury, especially in older individuals, which is associated with significant morbidity and mortality. In recent decades, there has been a great focus on early rehabilitation and discharge after hip fractures. The aim of such efforts is to minimize the financial and clinical burden of this condition. Read More

Cureus 2022 Aug 7;14(8):e27747. Epub 2022 Aug 7.

Trauma and Orthopaedics, The Western Health and Social Care Trust (HSCNI), Derry/Londonderry, GBR.

Introduction Hip fracture is commonly seen in elderly patients because of low-energy trauma. It carries significant morbidity and mortality. Scoring systems such as the Nottingham hip fracture score (NHFS) have shown a good correlation with increased mortality as the value of these scores increases. Read More

OTA Int 2022 Apr 18;5(2 Suppl):e191. Epub 2022 Apr 18.

Department of Trauma, Universitätsspital Zürich, Zurich, Switzerland.

Objective: To describe the surgical aspects potentially contributing to hardware failure of cephalomedullary nails.

Data Sources: A search of the Embase, PubMed (MEDLINE), Web of Science, and the Cochrane library for reports of hardware failures after intramedullary fixation of proximal femur fractures. Issues of cut out and cut through phenomena related to technique were excluded. Read More

Injury 2022 Aug 4. Epub 2022 Aug 4.

Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA 30912, United States.

Objective: To evaluate the cost-effectiveness of antibiotic cement-coated intramedullary nails (IMN) in the initial management of Gustilo-Anderson type Ⅲ (GAIII) open tibia fractures.

Methods: A break-even equation was used to analyze the costs associated with antibiotic cement-coated IMN and postoperative infection following GAⅢ open tibia fractures. This equation produced a new infection rate, which defines what percentage the antibiotic coated IMN needs to decrease the initial infection rate for its prophylactic use to be cost-effective. Read More

JAMA Dermatol 2022 Aug 10. Epub 2022 Aug 10.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Arch Orthop Trauma Surg 2022 Aug 10. Epub 2022 Aug 10.

Empiric Health (Olive), Asheville, NC, USA.

Introduction: Optimal treatment of high-risk ankle fractures in older, comorbid patients is unknown. Results of open reduction internal fixation (ORIF) versus tibiotalocalcaneal (TTC) fusion nailing for the treatment of high-risk geriatric ankle fractures were investigated.

Materials And Methods: Results of ORIF versus TTC fusion nailing were evaluated via retrospective case-control cohort study of 60 patients over age 50 with an open ankle fracture or one with at least 50% talar subluxation and at least 1 high-risk comorbidity: diabetes mellitus (DM), peripheral vascular disease, immunosuppression, active smoking, or a BMI > 35. Read More

J Drugs Dermatol 2022 Aug;21(8):897-899

Psoriasis, a chronic inflammatory skin condition, affects about 2% of children. A small subset have isolated nail involvement refractory to topical treatment that can be disabling. The development of targeted biologic agents offers safe, effective options for children with moderate-to-severe skin and nail disease. Read More

J Drugs Dermatol 2022 Aug;21(8):914-916

The aim of this retrospective study of patients affected by plaque psoriasis who underwent tildrakizumab therapy was to describe and compare the response of the nail psoriasis and the plaque psoriasis elsewhere in the body. Eight patients treated with tildrakizumab, 4 males and 4 females with a mean age of 61 years affected by psoriasis (mean baseline-PASI:13) with nail involvement (mean baseline mNAPSI: 51.9), were followed for at least 20 weeks. Read More

Orthop Surg 2022 Aug 10. Epub 2022 Aug 10.

Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai Pudong New District Zhoupu Hospital, Shanghai, China.

Objective: To compare the functional and alignment outcomes of intramedullary nail fixation using suprapatellar and infrapatellar approaches in treating distal tibial fractures.

Methods: In this retrospective study, 132 patients with distal tibial fractures (87 men, 45 women) ranging in age from 20 to 66 years were treated with intramedullary nails using the suprapatellar (69 patients) or infrapatellar (63 patients) approach. The radiographic alignment outcomes and ankle function were compared between the two groups. Read More

Orthop Traumatol Surg Res 2022 Aug 6:103390. Epub 2022 Aug 6.

Faculté de Médecine de Tours, 37032 Tours cedex 1, France; Service de Chirurgie Orthopédique et Traumatologique, CHRU Tours, 37044 Tours cedex 9, France. Electronic address:

Introduction: The severity of a foot or ankle deformity is a major prognostic factor for the success of ankle replacement. Varus deformity is at once the most arthrogenic and the most frequent.

Hypothesis: The severity of preoperative varus is a negative factor for ankle replacement survival. Read More

Eur J Orthop Surg Traumatol 2022 Aug 9. Epub 2022 Aug 9.

Limb Reconstruction and Bone Infection Service, The Royal London Hospital, Barts Health NHS Trust, Whitechapel Road, London, E1 1FR, UK.

Purpose: Fracture-related infections (FRI) following intramedullary nailing for tibial shaft fractures remain challenging to treat with associated high patient morbidity and health care costs. Recently, antibiotic-coated nails have been introduced as a strategy to reduce implant related infection rates in high-risk patients. We present the largest single-centre case series on ETN PROtect® outcomes reporting on fracture union, infection rates and treatment complications. Read More

Unfallchirurgie (Heidelb) 2022 Aug 9. Epub 2022 Aug 9.

Unfallchirurgie, Orthopädie und Sporttraumatologie, BG Klinikum Hamburg, Hamburg, Deutschland.

To remove a bent femoral nail is always a challenging task for a surgeon. In the last 20 years several case reports and descriptions of techniques are to be found in literature, the goal being to weaken the nail at the apex and then straightening it in situ in most cases. Those reports all have one parameter in common: the necessity to remove the nail relates to a refracture of the femur. Read More

Bone Joint Res 2022 Aug;11(8):585-593

Department of Orthopaedic and Trauma Surgery, Royal Infirmary of Edinburgh, The University of Edinburgh, Edinburgh, UK.

Aims: A number of anti-retroviral therapies (ART) have been implicated in potentially contributing to HIV-associated bone disease. The aim of this study was to evaluate the effect of combination ART on the fracture healing process.

Methods: A total of 16 adult male Wistar rats were randomly divided into two groups (n = eight each): Group 1 was given a combination of Tenfovir 30 mg, Lamivudine 30 mg, and Efavirenz 60 mg per day orally, whereas Group 2 was used as a control. Read More

J Clin Orthop Trauma 2022 Sep 19;32:101941. Epub 2022 Jul 19.

Department of Orthopaedic Surgery, Box Hill Hospital, Melbourne, Victoria, Australia.

Introduction: Tibial fractures are common long bone injuries, often surgically fixed with intramedullary nails. Modern intramedullary tibial nails allow for two different fixation modes, namely static and dynamic modes. While studies have demonstrated benefits of using either fixation modes, there has been no consensus as to which fixation mode would produce better outcomes and less complications. Read More

Work 2022 Aug 2. Epub 2022 Aug 2.

Non-Communicable Disease Research Center, Department of Occupational Health Engineering, School of Public Health, Sabzevar University of Medical Sciences, Sabzevar, Iran.

Background: The nail job is a new occupation in which the number of people who choose this job is rising. Therefore, the harmful hazards affecting the health of the practitioners should be taken into account.

Objective: The purpose of this study is to evaluate the ergonomics and occupational health hazards among nail technicians in Iranian society. Read More

J Obstet Gynaecol 2022 Aug 8:1-6. Epub 2022 Aug 8.

School of Medicine Valhalla, New York Medical College, Valhalla, NY, USA.

Current surgical scrub guidelines suggest that fingernail polish should not be worn by healthcare providers despite collective evidence not demonstrating a relationship between fingernail polish and surgical-site infection (SSI). The purpose of this study was to determine the effect of surgical staff wearing nail polish on the incidence of SSI after caesarean delivery. In this calendar block-randomised clinical trial, surgical staff were assigned to wear nail polish or to have unpainted nails for alternating two-week periods. Read More