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Foods 2022 Aug 4;11(15). Epub 2022 Aug 4.

Institute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.

The influence of semi-hard (C1), hard (C2), and soft whey cheese (C3) immersed in extra virgin olive oil (EVOO) on its oxidative and hydrolytic parameters, fatty acids, and phenolic composition during two months of simultaneous storage was investigated. Accelerated hydrolytic and oxidative degradation was noted in EVOO stored with the immersed cheese compared to control oil. Oxidation indicator (K), myristic (C 14:0), and -oleic fatty acid (C18:1t) exceeded the prescribed limit for the EVOO category in oils stored with immersed C1 and C2, which indicated that standard analytical parameters are ineffective as tools to examine the declared quality and authenticity of such topping oils. Read More

ACS Omega 2022 Jun 8;7(24):20619-20633. Epub 2022 Jun 8.

Department of Chemical Engineering, College of Biological and Chemical Engineering, Addis Ababa Science and Technology University, Addis Ababa 16417, Ethiopia.

Utilization of agricultural waste such as nonedible seed oil for the synthesis of biodiesel via catalytic transesterification is one of the effective ways for the partial replacement of petroleum-based fuels in the area of renewable energy development and is beneficial to CO, CO, and unburned hydrocarbon (HC) emission reduction to the environment. In this regard, the current study investigates the synthesis of fatty acid methyl esters (FAMEs) from kernel oil by considering parameter interaction and optimization to maximize the yield of fatty acid methyl esters (FAMEs). The response surface methodology-central composite design (RSM-CCD) was applied to optimize the fatty acid methyl ester (CMKO-FAME) synthesis process by varying the process parameters such as reaction time (1-2 h), molar ratio (6:1-12:1), and catalyst loading (1-2 wt %). Read More

Life (Basel) 2022 Jul 21;12(7). Epub 2022 Jul 21.

International Research and Innovation in Medicine Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Gestation and the neonatal period are crucial periods in infant development. Many components of breast milk, including fatty acids, play an important role in strengthening the immune system. The aim of our research was to evaluate the fatty acid profiles of milk from 69 mothers, including subjects having a normal weight, obesity, or gestational diabetes. Read More

Biosensors (Basel) 2022 Jul 6;12(7). Epub 2022 Jul 6.

Department of Physical and Analytical Chemistry, Institute of Biotechnology of Asturias, University of Oviedo, c/Julián Clavería 8, 33006 Oviedo, Spain.

Extracellular vesicles (EVs) are biological nanoparticles of great interest as novel sources of biomarkers and as drug delivery systems for personalized therapies. The research in the field and clinical applications require rapid quantification. In this study, we have developed a novel lateral flow immunoassay (LFIA) system based on FeO nanozymes for extracellular vesicle (EV) detection. Read More

Biomolecules 2022 06 29;12(7). Epub 2022 Jun 29.

State Key Laboratory of Conservation and Utilization of Subtropical Agro-Bioresources, College of Agriculture, Guangxi University, Nanning 530005, China.

Rice grain yield is a complex and highly variable quantitative trait consisting of several key components, including the grain weight, the effective panicles per unit area, and the grain number per panicle (GNPP). The GNPP is a significant contributor to grain yield controlled by multiple genes (QTL) and is crucial for improvement. Attempts have been made to find genes for this trait, which has always been a challenging and arduous task through conventional methods. Read More

Arch Anim Nutr 2022 Apr 22;76(2):145-158. Epub 2022 Jul 22.

Department of Animal Science, Faculty of Agriculture, Atatürk University, Erzurum, Turkey.

This study investigated the effect of feeding different levels of protected fat (calcium soaps of tallow) on fattening performance, carcass characteristics, meat quality, fatty acid composition of (LT) muscle and economic evaluation of 45 fat-tailed Morkaraman male lambs. The lambs were randomly divided into three groups including a control diet without protected fat (CON), supplemented with 2% protected fat (group PF2), and supplemented with 4% protected fat (group PF4) during the fattening period. Eight lambs randomly selected from each group were slaughtered to determine carcass characteristics and meat quality. Read More

FEBS Open Bio 2022 Jul 20. Epub 2022 Jul 20.

Department of Chemistry, Graduate School of Science, Chiba University, Japan.

Effective amelioration of type II diabetes requires therapies that increase both glucose uptake activity per cell and skeletal muscle mass. Myristic acid (14:0) increases diacylglycerol kinase (DGK) δ protein levels and enhances glucose uptake in myotubes in a DGKδ-dependent manner. However, it is still unclear whether myristic acid treatment affects skeletal muscle mass. Read More

Int J Cancer 2022 Jul 18. Epub 2022 Jul 18.

Trans Divisional Research Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

Prospective studies that objectively measure circulating levels of fatty acids are needed to clarify their role in the aetiology of breast cancer. Thirty-eight phospholipid fatty acids were measured using gas chromatograph in the plasma fraction of blood samples collected prospectively from 2,718 postmenopausal women (905 breast cancer cases) enrolled in the Cancer Prevention Study II Nutrition Cohort. Associations of 28 fatty acids that passed quality control metrics (modelled as per 1-standard deviation increase) with breast cancer risk were assessed using multiple variable conditional logistic regression models to compute odds ratios (OR) and 95% confidence intervals (CI). Read More

Molecules 2022 Jun 29;27(13). Epub 2022 Jun 29.

Graduate Program in Food Science, Department of Food Science and Technology, Federal University of Santa Catarina (UFSC), Florianopolis 88034-001, Brazil.

Arecaceae palm tree fruits (APTFs) with pulp or kernel rich in oil are widely distributed in six Brazilian biomes. APTFs represent a great potential for the sustainable exploitation of products with high added value, but few literature studies have reported their properties and industrial applications. The lack of information leads to underutilization, low consumption, commercialization, and processing of these fruit species. Read More

Saudi J Biol Sci 2022 Aug 20;29(8):103352. Epub 2022 Jun 20.

Department of Medical Laboratory Science, College of Applied Medical Science, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.

Some types of actinomycetes produce many different secondary metabolites of fatty acids, hydrocarbons, or other compounds. Many of these products play an important role in various medical fields. This study aims to extract natural compounds from actinomycetes after their isolation from the soil and their identification as antimicrobials. Read More

Int J Phytoremediation 2022 Jul 5:1-17. Epub 2022 Jul 5.

Department of Microbiology, School of Allied Health Sciences, Vinayaka Missions Research Foundation (DU), Salem, India.

A pilot-scale treatment method was used in the present study to test the biosorption of textile dye from textile effluent and carbon dioxide using RDS03. The textile dye effluent treatment achieved that textile dye biosorption capacity (q) rate of 98.84% on 15 days of treatment using RDS03. Read More

Pharmaceutics 2022 May 30;14(6). Epub 2022 May 30.

Department of Applied Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznan, Poland.

Lipid nanocarriers smaller than 200 nm may be used as pharmaceutical/cosmetic raw materials as they are able to penetrate the skin. The nanostructured lipid carriers (NLCs) based on microalgae oil () and lipids extracted from diatoms ( cf. (strain SZCZM1454A)) were produced by the HSH (high shear homogenization) method. Read More

Biomolecules 2022 05 24;12(6). Epub 2022 May 24.

Division of Diabetes, Endocrinology, and Metabolism, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Saturated fatty acids (SFAs) are considered to be detrimental to human health. One of the SFAs, myristic acid (MA), is known to exert a hypercholesterolemic effect in mice as well as humans. However, its effects on altering adipose tissue (AT) inflammation and systemic insulin resistance (IR) in obesity are still unclear. Read More

Biochem Pharmacol 2022 08 18;202:115150. Epub 2022 Jun 18.

Research Group of Molecular and Biochemical Pharmacology, Department of Biotechnology and Bioengineering, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address:

The expression of free fatty acid 1 receptors (FFA1R), activated by long chain fatty acids in human pancreatic β-cells and enhancing glucose-stimulated insulin secretion are an attractive target to treat type 2 diabetes. Yet several clinical studies with synthetic FFA1R agonists had to be discontinued due to cytotoxicity and/or so-called "liver concerns". It is not clear whether these obstructions are FFA1R dependent. Read More

Front Nutr 2022 2;9:913297. Epub 2022 Jun 2.

State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Food Nutrition and Safety, Ministry of Education of China, Tianjin University of Science and Technology, Tianjin, China.

Thermal treatment of lipids rich in fatty acids contributes to the formation of lipid oxidation products (LOPs), which have potentially harmful effects on human health. This study included soybean oil (SO), palm oil (PO), olive oil (OO), and lard oil (LO) as the research objects, with an aim to investigate the impact of heating temperature and fatty acid type on the generation of LOPs (α-dicarbonyl compounds, malondialdehyde (MDA), α,β-unsaturated aldehydes, and 16 volatile aldehydes). Results showed that LOPs increased significantly ( < 0. Read More

Biochim Biophys Acta Mol Cell Biol Lipids 2022 09 16;1867(9):159195. Epub 2022 Jun 16.

Rutgers Center for Lipid Research, New Jersey Institute for Food, Nutrition, and Health, Rutgers University, United States of America; Department of Nutritional Sciences, Rutgers University, United States of America. Electronic address:

Stearoyl-CoA desaturase-1 is an endoplasmic reticulum (ER)-membrane resident protein that inserts a double bond into saturated fatty acids, converting them into their monounsaturated counterparts. Previous studies have demonstrated an important role for SCD1 in modulating tissue and systemic health. Specifically, lack of hepatic or cutaneous SCD1 results in significant reductions in tissue esterified lipids. Read More

Res Vet Sci 2022 Dec 12;149:21-35. Epub 2022 Jun 12.

Department of Animal Science, Federal University of Espírito Santo, Alegre, ES, Brazil.

This study evaluated, through meta-analysis, the effect of distillers' grains (DG) supplementation to beef cattle on their performance, carcass parameters, and meat fatty acid profile. Eighty-one peer-reviewed publications with 439 treatments means were included in the data set. The effects of DG supplementation to beef cattle were evaluated using weighted mean differences (WMD) between the control group (diets with no DG) and DG group (diets with DG). Read More

Carbohydr Polym 2022 Sep 4;291:119566. Epub 2022 May 4.

Henan Province Engineering Research Center for Forest Biomass Value-added Products, School of Forestry, Henan Agricultural University, Zhengzhou 450002, China; Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries (AKUATROP), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia. Electronic address:

The effect of fatty acid type bonded to chitosan on the emulsifying properties of chitosan-based particles was investigated. Capric acid, myristic acid, and stearic acid were attached to chitosan chains. Longer fatty acids in the structure of chitosan lead to the better and more uniform formation of chitosan nanogels. Read More

Molecules 2022 May 25;27(11). Epub 2022 May 25.

Faculty of Food Science and Nutrition, Poznań University of Life Sciences, 60-637 Poznań, Poland.

New carriers of phytosterols; acylglycerols containing natural myristic acid at -1 and -3 positions and stigmasterol residue linked to -2 position by carbonate and succinate linker have been designed and synthesized in three-step synthesis from dihydroxyacetone (DHA). The synthetic pathway involved Steglich esterification of DHA with myristic acid; reduction of carbonyl group of 1,3-dimyristoylpropanone and esterification of 1,3-dimyristoylglicerol with stigmasterol chloroformate or stigmasterol hemisuccinate. The structure of the obtained hybrids was established by the spectroscopic methods (NMR; IR; HRMS). Read More

Foods 2022 Jun 4;11(11). Epub 2022 Jun 4.

Institute of Living Systems, Immanuel Kant Baltic Federal University, A. Nevskogo Street 14, Kaliningrad 236016, Russia.

Methods for purifying, detecting, and characterizing protein concentrate, carbohydrates, lipids, and neutral fats from the microalgae were developed as a result of research. Microalgae were collected from natural sources (water, sand, soil of the Kaliningrad region, Russia). Microalgae were identified based on morphology and polymerase chain reaction as Beijer, Gomont, (Nordst. Read More

Biotechnol Bioeng 2022 Jun 9. Epub 2022 Jun 9.

Microalgae Biotechnology Group, Key Laboratory of Biofuels, Key Laboratory of Shandong Province, Qingdao New Energy Shandong Laboratory, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.

High value unsaturated fatty acids can be produced by de novo synthesis in microalgal cells, especially via heterotrophic cultivation. Unfortunately, the lipid accumulation of heterotrophic microalgae cannot be improved efficiently in conventional ways. Here we reported heterotrophic Tribonema minus, a promising resource for the production of palmitoleic acid which has increasing demands in health service for patients with metabolic syndrome, as whole-cell biocatalyst to develop a novel way of shifting low value exogenous saturated fatty acids to high value ones. Read More

J Mol Biol 2022 06 26;434(11):167605. Epub 2022 Apr 26.

Biocomputing Group, Dept. of Pharmacy and Biotechnology, University of Bologna, Italy.

Myristoylation (MYR) is a protein modification where a myristoyl group is covalently attached to an exposed (N-terminal) glycine residue. Glycine myristoylation occurs during protein translation (co-translation) or after (post-translation). Myristoylated proteins have a role in signal transduction, apoptosis, and pathogen-mediated processes and their prediction can help in functionally annotating the fraction of proteins undergoing MYR in different proteomes. Read More

Int J Nanomedicine 2022 26;17:2413-2434. Epub 2022 May 26.

Riphah Institute of Pharmaceutical Sciences, Riphah International University Lahore Campus, Lahore, 54000, Pakistan.

Background: Most of the traditional nanocarriers of cancer therapeutic moieties present dose-related toxicities due to the uptake of chemotherapeutic agents in normal body cells. The severe life-threatening effects of systemic chemotherapy are well documented. Doxorubicin, DOX is the most effective antineoplastic agent but with the least specific action that is responsible for severe cardiotoxicity and myelosuppression that necessitates careful monitoring while administering. Read More

Front Vet Sci 2022 16;9:870901. Epub 2022 May 16.

Department of Animal Sciences, Food and Nutrition (DIANA), Facoltà di Scienze Agrarie, Alimentari e Ambientali, Università Cattolica del Sacro Cuore, Piacenza, Italy.

A group of 10 multiparous Italian Holstein cows were housed in individual tied stalls and infused with 150 ml of saline (CTR; 5 cows), or of 10% solution rich in long-chained omega-3 fatty acids (n3FA; 5 cows) at 12, 24, and 48 h after calving. From -7 to 21 days from calving (DFC), the body condition score, body weight, dry matter intake (DMI), and milk yield were measured, blood samples were collected to assess the plasma fatty acids (FA) and metabolic profiles, and milk samples were collected to assess the milk composition. Data underwent a mixed model for repeated measurements, including the treatment and time and their interactions as fixed effects. Read More

Food Res Int 2022 Jun 27;156:111304. Epub 2022 Apr 27.

Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province 650500, China. Electronic address:

Flavor is an important factor affecting the sensory of pomegranate and its products, which easily lose its freshness during processing and storage, but the biosynthesis of flavor-associated compounds is poorly understood until now. In this study, combining metabolome and transcriptome, flavor-associated attributes and volatile compounds of Tunisian pomegranate arils from 7 Chinese regions were studied. Depending on the different planting areas, there were significant differences in the content of sugars, organic acids and vitamin C. Read More

Food Res Int 2022 Jun 14;156:111365. Epub 2022 May 14.

Key Laboratory of Meat Processing and Quality Control, Ministry of Education, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

Leuconostoc mesenteroides are generally recognized as a group of specific spoilage organisms in meat and poultry products, which cause acidification and blown pack spoilage of meat. In this study, a total of 6 representative strains selected from 55 L. mesenteroides isolated from spoiled meat were tested to evaluate the spoilage ability by metabonomics and in-situ analysis. Read More

Wiad Lek 2022 ;75(4 pt 1):848-852

BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.

Objective: The aim: Evaluation of the influence of plant protection chemicals on the fatty acid composition of sunflower seeds.

Patients And Methods: Materials and methods: Study of the effects of pesticides, study of the effects of pesticides on the fatty acid composition (lipid) of sunflower seed by gas-liquid chromatography was studied.

Results: Results: It was found that the content of oleic and linoleic unsaturated fatty acids did not differ significantly from the control. Read More

Biomolecules 2022 05 22;12(5). Epub 2022 May 22.

Center for Food Analysis (NAL), Technological Development Support Laboratory (LADETEC), Federal University of Rio de Janeiro (UFRJ), Cidade Universitária, Rio de Janeiro 21941-598, Brazil.

Goat milk (GM) is an excellent alternative to cow milk and has recently been used in commercial infant formula preparation due to its superior fat composition. Here, the fatty acid (FA) composition, triacylglycerol (TAG) molecular species, thermal behavior and infrared spectra of extracted milk fat from the milk of the two main breeds of dairy goat bred in China (Guanzhong GM (GZG) and Xinong Saanen GM (XSG)) are investigated. Gas chromatography, Fourier-transform infrared spectroscopy, differential scanning calorimetry and ultra-performance convergence chromatography with quadrupole time-of-flight mass spectrometry are applied. Read More

Toxins (Basel) 2022 05 4;14(5). Epub 2022 May 4.

Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.

were evaluated in order to investigate the insecticidal activity towards adults. The LC values were promising and reflected the bio-efficacy of the tested extracts (39 and 42 mg/L), respectively, and reduced the fecundity markedly. Using GC/MS analysis, the major components were n-hexadecanoic, linolenic, hexadecenoic, myristic, stearic acids, linolelaidic acid, methyl ester and some terpenoids, alkaloids, and hydrocarbons. Read More

PLoS One 2022 26;17(5):e0258629. Epub 2022 May 26.

Department of Animal Science, School of Animal Science and Food Engineering, University of São Paulo, Rua Duque de Caxias Norte, Pirassununga, SP, Brazil.

The concern with human health has increased the interest in producing foods enriched with polyunsaturated fatty acids (PUFA), directly or naturally, by inclusion in the animals' diet. The positive effects such as antithrombotic, anti-inflammatory, and hypolipidemic have been observed in pigs and rats, used as human models for study. The present study evaluated the effect of cow's milk with different lipid profiles on performance, serum fatty acid profile, biochemical analysis, and a complete blood count of gilts used as a human model. Read More