Ann Biol Clin (Paris) 2018 Jun;76(3):259-269
Université Paris Descartes, Paris, France, Service de néphrologie, Hôpital Européen Georges Pompidou, Paris, Service de biochimie, Hôpital Européen Gorges Pompidou, AP-HP, Paris, France.
The analysis of urinary protein composition is an important step in the evaluation and monitoring of kidney diseases. Among the various approaches, the determination of urinary-specific proteins makes it possible to non-invasively detect a preferentially tubular or glomerular injury, to orientate towards a pathological process, to guide the indication of a kidney biopsy, and to follow the evolution of the disease and the effectiveness of a therapy. No study systematically evaluated the performance of urinary-specific proteins for the diagnosis of a renal disease. Read More