85,834 results match your criteria muscle mass


Midfoot and Ankle Mechanics in Block and Incline Heel Raise Exercises.

J Strength Cond Res 2021 Sep 23. Epub 2021 Sep 23.

Neuromusculoskeletal Mechanics Research Program, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.

Abstract: Chiu, LZF and Dæhlin, TE. Midfoot and ankle mechanics in block and incline heel raise exercises. J Strength Cond Res XX(X): 000-000, 2021-Although the heel raise exercise is performed to strengthen the calf muscles, the combination of calf muscle and ground reaction forces elicits moments that may deform the foot's longitudinal arch. Read More

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September 2021

The Effect of Immunomodulatory Treatments on Anti-Dystrophin Immune Response After AAV Gene Therapy in Dystrophin Deficient mdx Mice.

J Neuromuscul Dis 2021 Sep 23. Epub 2021 Sep 23.

School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA.

Background: AAV-based gene therapy is an attractive approach to treat Duchenne muscular dystrophy (DMD) patients. Although the long-term consequences of a gene therapy approach for DMD are unknown, there is evidence in both DMD patients and animal models that dystrophin replacement by gene therapy leads to an anti-dystrophin immune response that is likely to limit the long-term use of these therapeutic strategies.

Objective: Our objective is to test whether the anti-dystrophin immune response is affected by immunomodulatory drugs in mdx mice after rAAV gene therapy. Read More

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September 2021

Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy.

J Neuromuscul Dis 2021 Sep 23. Epub 2021 Sep 23.

School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY USA.

Recently, the Food and Drug Administration granted accelerated approvals for four exon skipping therapies -Eteplirsen, Golodirsen, Viltolarsen, and Casimersen -for Duchenne Muscular Dystrophy (DMD). However, these treatments have only demonstrated variable and largely sub-therapeutic levels of restored dystrophin protein in DMD patients, limiting their clinical impact. To better understand variable protein expression and the behavior of truncated dystrophin protein in vivo, we assessed turnover dynamics of restored dystrophin and dystroglycan complex (DGC) proteins in mdx mice after exon skipping therapy, compared to those dynamics in wild type mice, using a targeted, highly-reproducible and sensitive, in vivo stable isotope labeling mass spectrometry approach in multiple muscle tissues. Read More

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September 2021

Defecation Function After Laparo-Assisted Restorative Proctocolectomy with Ileal Pouch Anal Anastomosis for Ulcerative Colitis.

J Laparoendosc Adv Surg Tech A 2021 Sep 27. Epub 2021 Sep 27.

Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.

Defecation status is an important determinant of quality of life. Previous studies showed that postoperative defecation disorders occurred after open surgery for ulcerative colitis (UC), but few have investigated defecation status after laparo-assisted surgery. The added precision and magnification provided with laparo-assisted surgery should lead to less damage to the anal sphincter muscle. Read More

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September 2021

Comment on "Association between habitual coffee consumption and skeletal muscle mass in middle-aged and older Japanese people".

Geriatr Gerontol Int 2021 Sep 27. Epub 2021 Sep 27.

Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.

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September 2021

Accelerated Aging as a Paradigm to Understand the Late Effects of Cancer Therapies.

Front Horm Res 2021 Sep 24;54:1-9. Epub 2021 Sep 24.

Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

Long-term childhood adolescent and young adult (CAYA) cancer survivors may develop health conditions that often coexist at young adulthood or middle age and that normally occur in persons aged 65 years and older, including cardiovascular and musculoskeletal diseases, metabolic syndrome, and secondary malignancies, suggesting that a process of accelerated aging occurs. This chapter summarizes epidemiological evidence and physiological mechanisms of accelerated aging, and possible preventive measures to delay the process of accelerated aging in CAYA cancer survivors. Evidence is mounting that in addition to a high prevalence of specific and multiple aging-related chronic diseases (multimorbidity), CAYA cancer survivors seem to also have a higher risk of other aging phenotypes, including frailty, poor physical performance, and changes in body composition (low muscle and high fat mass). Read More

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September 2021

Effects of resistance training on muscle strength, body composition and immune-inflammatory markers in people living with HIV: a systematic review and Meta-analysis of randomized controlled trials.

HIV Res Clin Pract 2021 Sep 25:1-9. Epub 2021 Sep 25.

Postgraduate Program in Physical Education, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.

The purpose of this review is to evaluate the effect of resistance training (RT) as a unique intervention on muscle strength, body composition, and immune-inflammatory markers in people living with HIV (PLHIV). The searches were conducted in seven databases and included published randomized clinical trials that assessed the effect of RT vs. no exercise on muscle strength, body composition, and immune-inflammatory markers in PLHIV until June 2021. Read More

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September 2021

Effects of exercise training on bone mineral density in adults living with HIV: a retrospective study.

HIV Res Clin Pract 2021 Sep 25:1-10. Epub 2021 Sep 25.

Laboratory of Physical Activity and Health Promotion, Institute of Physical Education and Sports, University of Rio de Janeiro State, Rio de Janeiro, RJ, Brazil.

Evidence on the effects of exercise training on the bone health of men and women living with HIV (MLHIV and WLHIV) is limited. To investigate the effects of a long-term multimodal exercise program on the bone mineral density (BMD) of MLHIV and WLHIV. A retrospective cohort of 39 patients (13 women; 48. Read More

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September 2021

Childhood Bradycardia Associates With Atrioventricular Conduction Defects in Older Age: A Longitudinal Birth Cohort Study.

J Am Heart Assoc 2021 Sep 25:e021877. Epub 2021 Sep 25.

University College London (UCL) Medical Research Council (MRC) Unit for Lifelong Health and AgeingUniversity College London London United Kingdom.

Background This study explored the association between childhood bradycardia and later-life cardiac phenotype using longitudinal data from the 1946 National Survey of Health and Development (NSHD) birth cohort. Methods and Results Resting heart rate was recorded at 6 and 7 years of age to provide the bradycardia exposure defined as a childhood resting heart rate <75 bpm. Three outcomes were studied: (1) echocardiographic data at 60 to 64 years of age, consisting of ejection fraction, left ventricular mass index, myocardial contraction fraction index, and E/e'; (2) electrocardiographic evidence of atrioventricular or ventricular conduction defects by 60 to 64 years of age; and (3) all-cause and cardiovascular mortality. Read More

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September 2021

The estrous cycle and skeletal muscle atrophy: Investigations in rodent models of muscle loss.

Exp Physiol 2021 Sep 26. Epub 2021 Sep 26.

Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, United States.

New Findings: What is the central question of this study? Is the estrous cycle affected during disuse atrophies and if so, how do estrous cycle changes relate to musculoskeletal outcomes? What is the main finding and its importance? Rodent estrous cycles are altered during disuse atrophy, which corresponds to musculoskeletal outcomes. However, the estrous cycle does not appear changed in Lewis Lung Carcinoma, which corresponded to no differences in muscle size compared to healthy controls. These findings suggest a relationship between estrous cycle and muscle size during atrophic pathologies. Read More

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September 2021

Profoundly lower muscle mass and rate of contractile protein synthesis in boys with Duchenne muscular dystrophy.

J Physiol 2021 Sep 26. Epub 2021 Sep 26.

Department of Nutritional Sciences and Toxicology, University of California, Berkeley.

Duchenne muscular dystrophy results in a progressive loss of functional skeletal muscle but total body functional muscle mass or rates of muscle protein synthesis have not previously been assessed in these patients. D creatine dilution was used to measure total functional muscle mass and oral H O was used to examine the rates of muscle protein synthesis non-invasively in boys with DMD and healthy controls using urine samples. Muscle mass was profoundly lower in DMD compared to control subjects, particularly in older, non-ambulant patients. Read More

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September 2021

Relationship of Biological Maturation with Muscle Power in Young Female Athletes.

Int J Exerc Sci 2021 1;14(6):696-706. Epub 2021 Aug 1.

Health Sciences Center, Department of Physical Education - Federal University of Rio Grande do Norte, UFRN, Natal, RN, BRAZIL.

There is still no consensus on how biological maturation (BM) affects the muscle power of upper and lower limbs in young people. The objective was to verify associations between BM and muscle power, as well as to compare the muscle power of upper (ULP) and lower limbs (LLP) among young athletes in different stages of BM. The sample consisted of 79 female athletes (10. Read More

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Order of Resistance Training Cycles to Develop Strength and Muscle Thickness in Resistance-Trained Men: A Pilot Study.

Int J Exerc Sci 2021 1;14(4):644-656. Epub 2021 Aug 1.

Human Performance Research Laboratory, Methodist University of Piracicaba, Piracicaba, São Paulo, BRAZIL.

The aim of the present study was to assess the chronic effects of different order of resistance training cycles on strength and muscle thickness of recreationally resistance-trained men. The study sample was composed of 16 healthy men (age: 25.0 ± 3. Read More

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Acute Effect of Different Duration of Foam Rolling Protocols on Muscle Thickness, Pain Pressure Threshold, and Volume Load on Multiple Sets of Knee Extension.

Int J Exerc Sci 2021 1;14(3):742-755. Epub 2021 Aug 1.

Human Performance Research Laboratory, Human Movement Sciences Postgraduate Program, Methodist University of Piracicaba, Piracicaba, BRAZIL.

Previous studies investigated the effects of foam rolling (FR) on measurements of strength and power. However, the acute effect of FR on muscle thickness (MT) and pressure pain threshold (PPT) after multiple sets of resistance exercise remains to be elucidated. The aim of the present study was to examine the effect of one and three minutes of quadriceps FR on muscle thickness (vastus lateralis [VL] and rectus femoris [RF]), pain threshold (VL and RF), and total load lifted (TLL) on multiple sets of knee extension. Read More

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Beta-alanine Supplementation for Four Weeks Increases Volume Index and Reduces Perceived Effort of Resistance-trained Men: A Pilot Study.

Int J Exerc Sci 2021 1;14(2):994-1003. Epub 2021 Aug 1.

Human Performance Research Laboratory, Methodist University of Piracicaba, Piracicaba, São Paulo, BRAZIL.

The aim of the present study was to assess the short-term effects of four weeks of beta-alanine supplementation (BA) (6.4 g/day) on the total volume performed and perceived effort of resistance-trained individuals. Sixteen trained men (age: 27. Read More

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The Influence of a Total Body Resistance Training Program on Autonomic Modulation and Strength Variables in Young Adults.

Int J Exerc Sci 2021 1;14(2):802-814. Epub 2021 Aug 1.

Integrative Exercise Physiology Laboratory, School of Kinesiology, Ball State University, Muncie, IN, USA.

The purpose of this study was to examine autonomic modulation using multiple quantitative measures before and after a resistance training (RT) intervention. Seventeen young adults (age 18-35 years) were tested for body composition, muscular strength, and autonomic activity. The RT protocol targeted total-body large muscle groups, which were performed three days a week for eight-weeks. Read More

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GH Overexpression Alters Spermatic Cells MicroRNAome Profile in Transgenic Zebrafish.

Front Genet 2021 8;12:704778. Epub 2021 Sep 8.

Laboratório de Genômica Estrutural, Programa de Pós-Graduação em Biotecnologia, Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, Brazil.

Overexpression of growth hormone (GH) in -transgenic zebrafish of a highly studied lineage F0104 has earlier been reported to cause increased muscle growth. In addition to this, GH affects a broad range of cellular processes in transgenic fish, such as morphology, physiology, and behavior. Reports show changes such as decreased sperm quality and reduced reproductive performance in transgenic males. Read More

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September 2021

Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes.

Front Immunol 2021 8;12:689966. Epub 2021 Sep 8.

Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Background: Most of the explanatory and prognostic models of COVID-19 lack of a comprehensive assessment of the wide COVID-19 spectrum of abnormalities. The aim of this study was to unveil novel biological features to explain COVID-19 severity and prognosis (death and disease progression).

Methods: A predictive model for COVID-19 severity in 121 patients was constructed by ordinal logistic regression calculating odds ratio (OR) with 95% confidence intervals (95% CI) for a set of clinical, immunological, metabolomic, and other biological traits. Read More

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September 2021

Effect of Seat Backrest Inclination on the Muscular Pattern and Biomechanical Parameters of the Sit-to-Stand.

Front Hum Neurosci 2021 9;15:678302. Epub 2021 Sep 9.

Laboratoire CIAMS, Université Paris-Saclay, Saint Aubin, France.

The sit-to-stand (STS) transfer mobilizes an extended part of the kinematic chain throughout a postural phase characterized by a flexion of the trunk and a focal phase consisting of a whole-body extension. The aim of this study was to analyze the variations of the global muscular pattern and the biomechanical parameters in both phases, in relation with seat backrest inclination. Fifteen participants were asked to stand up from a seat with 5 backrest inclination settings and at 2 execution speeds. Read More

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September 2021

Collision Tumor of the Kidney: Renal Cell Carcinoma Hidden in a Giant Angiomyolipoma in a Patient With Tuberous Sclerosis Complex.

Ochsner J 2021 ;21(3):287-290

Department of Urology, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

A renal angiomyolipoma is a mixed mesenchymal benign tumor composed of smooth muscle, adipose tissue, and blood vessels. Malignant transformation of angiomyolipomas is anecdotal. To our knowledge, only 6 cases have been reported, and 4 of the patients had tuberous sclerosis complex diagnosed. Read More

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January 2021

The Association of Systemic Interleukin 6 and Interleukin 10 Levels with Sarcopenia in Elderly Patients with Chronic Obstructive Pulmonary Disease.

Int J Gen Med 2021 18;14:5893-5902. Epub 2021 Sep 18.

Department of Orthopedics, The Sixth Hospital of Shanxi Medical University, Taiyuan, 030000, People's Republic of China.

Objective: Chronic obstructive pulmonary disease (COPD) is often associated with sarcopenia, and systemic inflammation is an underlying pathogenesis of COPD. In this study, the effects of interleukin (IL)- 6 and IL-10 levels on sarcopenia in patients with COPD were investigated.

Methods: Seventy-three patients (59 males and 14 females), aged 60-93 years old, who had stable COPD (not including patients with advanced lung decline) were enrolled in this study. Read More

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September 2021

Dietary patterns and sarcopenia in elderly adults: the TCLSIH study.

Br J Nutr 2021 Sep 27:1-26. Epub 2021 Sep 27.

Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.

Sarcopenia is a core contributor to several health consequences, including falls, fractures, physical limitations, and disability. The pathophysiological processes of sarcopenia may be counteracted with the proper diet, delaying sarcopenia onset. Dietary pattern analysis is a whole diet approach used to investigate the relationship between diet and sarcopenia. Read More

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September 2021

A renal angiomyolipoma with a challenging presentation: a case report.

J Med Case Rep 2021 Sep 27;15(1):477. Epub 2021 Sep 27.

University of Tunis ElManar, Tunis, Tunisia.

Introduction: Renal angiomyolipoma is considered a benign mesenchymal tumor composed of fat, smooth muscle, and blood vessels. It represents 1-3% of solid renal tumors. Despite this tumor's benignity, it can be aggressive with a locoregional extension. Read More

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September 2021

Prescription and Effects of Strength Training in Individuals with Intellectual Disability-A Systematic Review.

Sports (Basel) 2021 Sep 4;9(9). Epub 2021 Sep 4.

Faculty of Sport Sciences and Physical Education, University of Coimbra, 3040-248 Coimbra, Portugal.

The practice of physical exercise (PE), especially strength training (ST), has health benefits in the healthy population; however, the literature is scarce in the recommendations related to the population with intellectual disability (ID). This study represents the first analysis on the topic and aims to examine the structure and efficacy of ST experimental intervention programs in individuals with ID. This systematic review was carried out between January and April 2021, using the PubMed, Web of Science, Scopus, and SPORTDiscus databases, according to the PRISMA guidelines. Read More

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September 2021

Regeneration in Reptiles Generally and the New Zealand Tuatara in Particular as a Model to Analyse Organ Regrowth in Amniotes: A Review.

J Dev Biol 2021 Aug 30;9(3). Epub 2021 Aug 30.

Agricultural Science and Technology Research Institute, Andong National University, Andong 36729, Korea.

The ability to repair injuries among reptiles, i.e., ectothermic amniotes, is similar to that of mammals with some noteworthy exceptions. Read More

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Dietary intake and nutritional status in adolescents and young adults with anorexia nervosa: A 3-year follow-up study.

Clin Nutr 2021 Aug 24;40(10):5391-5398. Epub 2021 Aug 24.

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Background & Aims: Patients with anorexia nervosa (AN) restrict their dietary intake leading to malnutrition. Information is scarce on nutrition status during recovery. The aim of the study was to investigate dietary intake, body composition, biochemistry, and status in young women three years after hospital treatment due to severe restrictive AN. Read More

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Insulin resistance and insulin sensitizing agents.

Metabolism 2021 Sep 23:154892. Epub 2021 Sep 23.

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine University Düsseldorf, Düsseldorf, Germany; German Center for Diabetes Research, Partner Düsseldorf, München-Neuherberg, Germany; Department of Endocrinology and Diabetology, Medical Faculty and University Hospital, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany. Electronic address:

Insulin resistance is a common feature of obesity and type 2 diabetes, but novel approaches of diabetes subtyping (clustering) revealed variable degrees of insulin resistance in people with diabetes. Specifically, the severe insulin resistant diabetes (SIRD) subtype not only exhibits metabolic abnormalities, but also bears a higher risk for cardiovascular, renal and hepatic comorbidities. In humans, insulin resistance comprises dysfunctional adipose tissue, lipotoxic insulin signaling followed by glucotoxicity, oxidative stress and low-grade inflammation. Read More

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September 2021

A rare association in a patient with non-muscle invasive bladder cancer: ureteral fibroepithelial polyp and ipsilateral renal cell carcinoma: a case report.

J Med Case Rep 2021 Sep 26;15(1):475. Epub 2021 Sep 26.

Department of Urology, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Tr- 34668, Istanbul, Turkey.

Background: Fibroepithelial polyps located in the ureter constitute 2-6% of all benign tumors in the urinary system. Distinguishing these lesions from transitional cell carcinoma is essential to avoid unnecessary nephroureterectomy.

Case Presentation: A 59-year-old asymptomatic caucasian male patient was enrolled in follow-up for Ta low-grade transitional cell bladder cancer 4 years ago in our clinic. Read More

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September 2021

Desmoid fibromatosis of the breast; a rare case report.

Int J Surg Case Rep 2021 Sep 6;87:106363. Epub 2021 Sep 6.

Smart Health Tower, Madam Mitterrand Str, Sulaimani, Kurdistan, Iraq.

Introduction: Desmoid tumor is an uncommon tumor with variable spectrum ranged from being a locally lesion to an aggressive and destructive one. The current case aims to report a rare condition of desmoid type fibromatosis of the breast.

Presentation Of Case: A 59-year-old female presented with a right breast mass for 9-months. Read More

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September 2021

Simulated microgravity accelerates aging of human skeletal muscle myoblasts at the single cell level.

Biochem Biophys Res Commun 2021 Sep 20;578:115-121. Epub 2021 Sep 20.

Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Earth's gravity is essential for maintaining skeletal muscle mass and function in the body. The role of gravity in the myogenic mechanism has been studied with animal experiments in the International Space Station. Recently, gravity-control devices allow to study the effects of gravity on cultured cells on the ground. Read More

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September 2021