21,091 results match your criteria multiple mononeuropathy


Health economic evaluation of different treatment strategies for peripheral entrapment mononeuropathies: a systematic review.

Expert Rev Pharmacoecon Outcomes Res 2021 May 5:1-10. Epub 2021 May 5.

College of Pharmaceutical Sciences, Soochow University, Suzhou, China.

: In this era of cost-conscious health systems, it is of utmost importance to identify and establish the most cost-effective treatment option. However, in the case of peripheral entrapment mononeuropathies there is alack of data regarding economically effective treatment strategies. Therefore, the objective was to conduct an economic evaluation including both costs and benefits of various treatment strategies applied to peripheral entrapment mononeuropathies to estimate the relative cost-effective treatment regimens. Read More

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Numbness of the lower lip following urological surgery under general anesthesia - A case report.

Anesth Pain Med (Seoul) 2021 Apr 8;16(2):201-204. Epub 2021 Apr 8.

Department of Anesthesiology and Pain Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.

Background: Peripheral nerve injury is a complication that can occur after general anesthesia. It significantly impairs the patient's quality of life and may lead to permanent disability. Nerves in several areas can be damaged during the perioperative period, but it is very rare that numbness of the lower lip is caused after general anesthesia. Read More

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Peripheral nervous system manifestations of rheumatological diseases.

J Neurol Sci 2021 May 27;424:117421. Epub 2021 Mar 27.

University of Virginia, Department of Neurology, Charlottesville, VA, USA.

Rheumatological diseases result in immune-mediated injury to not only connective tissue, but often components of the peripheral nervous system. These overlap conditions can be broadly categorized as peripheral neuropathies and overlap myositis. The peripheral neuropathies are distinctive as many have unusual presentations such as non-length-dependent, small fiber neuropathies and sensory neuronopathies (both due to dorsal root ganglia dysfunction), multiple mononeuropathies (e. Read More

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Aseptic hypertrophic pachymeningitis in a patient with Rheumatoid Arthritis - a case of involvement of the central nervous system by the disease?

Acta Reumatol Port 2021 Jan-Mar;46(1):69-71

Centro Hospitalar de São João.

Hypertrophic pachymeningitis (HP) is a rare clinical entity which uncommonly occurs in rheumatoid arthritis (RA) patients. We describe the case of a rheumatoid factor and anti-citrullinated protein antibody positive RA male that was diagnosed with HP and multiple mononeuropathy. Although histological evaluation was not performed, after excluding infectious and neoplastic causes, it was possible to determine a probable inflammatory etiology. Read More

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[Triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) for trunk-sciatica].

Zhongguo Zhen Jiu 2021 Mar;41(3):275-8

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Objective: To compared the clinical effect between triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) and triple needling combined with electroacupuncture at Huantiao (GB 30) for trunk-sciatica.

Methods: A total of 56 patients with trunk-sciatica were randomized into a triple needling combined with thermo-electroacupuncture group and a triple needling combined with electroacupuncture group, 28 cases in each group. In the triple needling combined with thermo-electroacupuncture group, triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) was applied. Read More

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[Effect of moxibustion on expression of GAP-43 in sciatic nerve trunk and ventral horn of spinal cord of rats with primary sciatica and its nerve repair function].

Zhongguo Zhen Jiu 2021 Feb;41(2):183-8

Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei 230000, China.

Objective: To observe the effect of moxibustion at "Huantiao" (GB 30) on the expression of growth-associated protein-43 (GAP-43) in the sciatic nerve trunk and ventral horn of spinal cord (L-L) in rats with primary sciatica, and to explore the mechanism of moxibustion in improving primary sciatica.

Methods: A total of 48 healthy male SD rats were randomly divided into a normal group, a sham operation group, a model group and a moxibustion group, 12 rats in each group. The rat model of primary sciatic pain was established by chronic constriction injury (CCI) of the sciatic nerve in the model group and the moxibustion group. Read More

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February 2021

The study on the clinical effectiveness and safety of traditional Chinese medicine acupoint catgut embedding guided by musculoskeletal ultrasound in the treatment of nerve root sciatica: A protocol for systematic review and meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2021 Apr;100(13):e25387

Department of Ultrasound.

Background: Nerve root sciatica (NRS) is a common orthopedic disease, which usually occurs between 20 and 40 years of age, and the incidence rate is increasing year by year and is being younger. The disease has no special effect of treatment, clinically generally taking the symptomatic treatment, such as taking short-term glucocorticoids, sedatives, analgesics, and so on. Long-term use of drugs will adversely affect the patient's gastrointestinal tract, liver, and kidney function. Read More

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Marinacci anastomosis (reverse Martin-Gruber anastomosis): A case report.

Medicine (Baltimore) 2021 Apr;100(13):e25073

Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital.

Rationale: The incidence of Martin-Gruber anastomosis ranges from 5% to 34%, which is characterized by crossing over from the median to the ulnar nerve and innervating the first dorsal interosseous, thenar or hypothenar muscles. However, the reverse Martin-Gruber anastomosis, or Marinacci anastomosis, is far less discussed and appears in recent literature.

Patient Concerns: A 56-year-old man presented to the clinic of a university hospital because of left neck soreness with numbness radiating to the left lateral shoulder. Read More

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Minocycline alleviates peripheral nerve adhesion by promoting regulatory macrophage polarization via the TAK1 and its downstream pathway.

Life Sci 2021 Jul 27;276:119422. Epub 2021 Mar 27.

Department of Hand Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun 130033, PR China. Electronic address:

Aims: Inflammation plays a key role in peripheral nerve adhesion and often leads to severe pain and nerve dysfunction. Minocycline was reported to have potent anti-inflammatory effects and might be a promising drug to prevent or attenuate peripheral nerve adhesion. The present study aimed to clarify whether minocycline contributes to nerve adhesion protection and its underlying mechanism. Read More

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An unusual cause of sciatica in an immunocompromised patient.

BMJ 2021 03 24;372:n632. Epub 2021 Mar 24.

Anti-retroviral Therapy Centre, District Hospital Khagaria, Khagaria, India.

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Little needle-scalpel for piriformis syndrome: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Mar;100(12):e25242

Jiangxi University of Traditional Chinese Medicine.

Background: Piriformis syndrome (PS) is a condition in which the sciatic nerve is compressed when passing through the inferior mouth of the piriformis muscle, mainly caused by pain in one hip and leg. In severe cases, patients may experience severe buttock and lower limb pain, discomfort, difficulty walking, and claudication. It is estimated that the annual incidence of low back pain and sciatica is about 40 million cases, and the annual incidence of piriformis syndrome is about 2. Read More

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Ulnar Neuropathy After Intermittent Prone Positioning for COVID-19 Infection: A Preliminary Report of 3 Cases.

JBJS Case Connect 2021 03 19;11(1). Epub 2021 Mar 19.

Department of Orthopaedic Surgery, Long Island Jewish Medical Center, New Hyde Park, New York.

Case: We describe a preliminary report of 3 cases of ulnar neuropathy after coronavirus disease 2019 (COVID-19) infection and treatment with intermittent prone positioning.

Conclusion: Ulnar neuropathy may be associated with recent COVID-19 infection. The natural process of the disease and intermittent prone positioning are likely risk factors contributing to this finding. Read More

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Mononeuropathy multiplex associated with systemic vasculitis: A case report.

World J Clin Cases 2021 Mar;9(7):1741-1747

Department of Rehabilitation Medicine, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul 07061, South Korea.

Background: Vasculitis, a systemic disorder with inflammation of blood vessel walls, can develop broad spectrum of signs and symptoms according to involvement of various organs, and therefore, early diagnosis of vasculitis is challenging. We herein describe a patient who developed a special case of systemic vasculitis with mononeuropathy multiplex, rectal perforation and antiphospholipid syndrome (APS) presented with pulmonary embolism.

Case Summary: A 61-year-old woman visited hospital with complaints of myalgia and occasional fever. Read More

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Thumb radial abduction angle and its association with handgrip strength, dexterity and carpel tunnel syndrome susceptibility among saudi dental students.

Niger J Clin Pract 2021 Mar;24(3):299-307

Department of Pediatric Dentistry and Orthodontics, King Khalid University College of Dentistry, Abha, Kingdom of Saudi Arabia.

Background: Dental professionals are prone to carpal tunnel syndrome (CTS) and other nerve-related disorders as they perform repetitive wrist work with static physical position for long hours.

Objectives: To evaluate the relationship of thumb radial abduction angle with handgrip strength, hand dexterity, and CTS susceptibility among Saudi senior dental students and interns. The study also intends to compare thumb radial abduction angle based on the gender. Read More

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A Screening Method Using Anomaly Detection on a Smartphone for Patients With Carpal Tunnel Syndrome: Diagnostic Case-Control Study.

JMIR Mhealth Uhealth 2021 03 14;9(3):e26320. Epub 2021 Mar 14.

Department of Functional Joint Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Background: Carpal tunnel syndrome (CTS) is a medical condition caused by compression of the median nerve in the carpal tunnel due to aging or overuse of the hand. The symptoms include numbness of the fingers and atrophy of the thenar muscle. Thenar atrophy recovers slowly postoperatively; therefore, early diagnosis and surgery are important. Read More

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Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management.

Brain 2021 Mar 12. Epub 2021 Mar 12.

Department of Neurology, University of Michigan, Ann Arbor, MI, USA.

Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes. Up to half of patients with diabetes develop neuropathy during the course of their disease, which is accompanied by neuropathic pain in to 30-40% of cases. Peripheral nerve injury in diabetes can manifest as progressive distal symmetric polyneuropathy, autonomic neuropathy, radiculo-plexopathies, and mononeuropathies. Read More

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The current burden of diabetic foot disease.

J Clin Orthop Trauma 2021 Jun 8;17:88-93. Epub 2021 Feb 8.

Diabetic Foot Clinic and Diabetic Department, King's College Hospital, London, SE5 9RS, UK.

Neuropathy and ischaemia are two great pathologies of the diabetic foot which lead to the characteristic features of foot ulceration (neuropathic and ischaemic) and Charcot neuroarthropathy. These can be complicated by infection and eventually may result in amputation (minor or major) and increased mortality. All of these features contribute to considerable clinical and economic burden. Read More

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Effectiveness of Conservative Treatment According to Severity and Systemic Disease in Carpal Tunnel Syndrome: A Systematic Review.

Int J Environ Res Public Health 2021 02 28;18(5). Epub 2021 Feb 28.

Physiotherapy Department, Faculty of Health Sciences, Universidad de Zaragoza, 50009 Zaragoza, Spain.

(1) Background: Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy in the upper extremity. Conservative treatment has been effective for mild and moderate idiopathic CTS. However, severe CTS and systemic conditions were an exclusion criterion from the studies. Read More

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February 2021

Carpal Tunnel Syndrome: A National Survey to Monitor Knowledge and Operating Methods.

Int J Environ Res Public Health 2021 02 18;18(4). Epub 2021 Feb 18.

Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, I-00133 Rome, Italy.

The aim of this article was to investigate the knowledge, management, and clinical practice of Italian physiotherapists concerning patients with carpal tunnel syndrome (CTS). A national cross-sectional survey consisted of 24 questions was administered from December 2019 until February 2020. A Chi-squared independence test was run to study any difference between subgroups of the sample and responses to the questionnaire. Read More

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February 2021

Warm acupuncture therapy for Primary sciatica: A protocol of systematic review and meta-analysis.

Medicine (Baltimore) 2021 Feb;100(8):e24551

Jiangxi University of Traditional Chinese Medicine.

Introduction: This meta-analysis aims to assess the effectiveness and safety of warm acupuncture therapy for treating Primary sciatica.

Methods: The following 9 databases will be search from their inception to December 6, 2020: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), the Chinese Biomedical Literature Database (CBM), the Chinese Medical Current Content (CMCC), the Wan-Fang Database and the China National Knowledge Infrastructure (CNKI). Randomized controlled trials (RCTs) of warm acupuncture for treating Primary sciatica, Chinese or Japanese without restriction of publication status will be included. Read More

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February 2021

Superb microvascular imaging for detecting carpal tunnel syndrome compared with power Doppler ultrasonography: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Mar;100(9):e24575

Orthopedics Department, First Affiliated Hospital of Dalian Medical University, Dalian, China.

Background: Sonography enhances diagnostic accuracy by the detection of the epineural or intraneuronal blood flow.[1-4] Power Doppler ultrasonography (PDUS) in carpal tunnel syndrome (CTS) has been previously studied and shown to be valid and reliable for grading the intraneural flow.[3,4] However, superb microvascular imaging (SMI) represents a new era in diagnostic sonography, and this new technology enables accurate visualization of vascular structures with intensive clutter suppression to provide flow signals for large to small vessels, and it presents these data at high frame rates. Read More

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Optimizing Investigations for Evaluation of Enlargements of the Roots, Plexuses and Nerves: A Study of 133 Patients.

Ann Indian Acad Neurol 2020 Sep-Oct;23(5):666-673. Epub 2019 Dec 6.

Department of Pathology, Foundation for Medical Research Lab, Mumbai, Maharashtra, India.

Background And Aims: A wide variety of neurological diseases result in clinical and/or radiological enlargement of nerves, roots and plexuses. With the advancement in techniques and use of magnetic resonance neurography (MRN), aided by electrophysiology, proximal segments of the lower motor neuron (LMN) can be well studied. The relative merits of investigative modalities have not been well defined and comprehensive information on this subject is sparse. Read More

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December 2019

Functional Electrical Stimulation for Foot Drop in Post-Stroke People: Quantitative Effects on Step-to-Step Symmetry of Gait Using a Wearable Inertial Sensor.

Sensors (Basel) 2021 Jan 29;21(3). Epub 2021 Jan 29.

Rehabilitation Sciences Graduate Program, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre 90050-170, Brazil.

The main purpose of the present study was to assess the effects of foot drop stimulators (FDS) in individuals with stroke by means of spatio-temporal and step-to-step symmetry, harmonic ratio (HR), parameters obtained from trunk accelerations acquired using a wearable inertial sensor. Thirty-two patients (age: 56.84 ± 9. Read More

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January 2021

Angiographic Findings of the Median Artery in Two Patients with Carpal Tunnel Syndrome.

J Hand Surg Asian Pac Vol 2021 Mar;26(1):96-99

Department of Orthopaedic Surgery, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.

Carpal tunnel syndrome (CTS) is the most common type of entrapment neuropathy. The majority of CTS cases are idiopathic and affect females between 40 and 60 years old. Conversely, this report describes two female patients in their mid-30's diagnosed with CTS caused by a median artery in the carpal tunnel using ultrasonography. Read More

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Diagnosis and treatment of persons with acute thallium poisoning.

Toxicol Rep 2021 24;8:277-281. Epub 2021 Jan 24.

N.V. Sklifosovsky Research Institute for Emergency Medicine of the Department of Health of Moscow, 3 Bolshaya Sukharevskaya sq., Moscow, 129090, Russian Federation.

Objective: This study aimed to describe organs and systems damages in persons after mass poisoning with thallium and show the results of treatment.

Methods: Forty-four persons (12 males and 32 females) with acute oral thallium poisoning were tested for thallium levels in blood and urine and examined by a toxicologist and a neurologist, and in some -cases, by a gynecologist, an ophthalmologist, and a psychiatrist. Persons were divided into the following three groups depending on the severity of the poisoning: I: This group consisted of 9 persons (blood thallium level 8. Read More

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January 2021

Superficial peroneal nerve neuroma after syndesmotic stabilisation surgery.

BMJ Case Rep 2021 Feb 4;14(2). Epub 2021 Feb 4.

Trauma and Orthopaedics, Galway University Hospitals, Galway, Ireland.

The ankle is a region crowded with multiple neurovascular and musculotendinous structures. We describe a case of a rare neurological complication following ankle surgery. Read More

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February 2021

Ultrasound scanning in the diagnosis of peripheral neuropathies.

Pract Neurol 2021 Feb 4. Epub 2021 Feb 4.

Neurology, Elisabeth-TweeSteden Ziekenhuis, Tilburg, Noord-Brabant, The Netherlands.

Nerve ultrasound scanning has become a valuable diagnostic tool in the routine workup of peripheral nerve disorders, effectively complementing conventional electrodiagnostic studies. The most relevant sonographic features are nerve size and structural integrity. Several peripheral neuropathies show characteristic and distinct patterns of nerve enlargement, allowing their early and accurate identification, and reducing test-burden and diagnostic delay for patients. Read More

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February 2021

Microarray analysis reveals an inflammatory transcriptomic signature in peripheral blood for sciatica.

BMC Neurol 2021 Feb 3;21(1):50. Epub 2021 Feb 3.

Cervicodynia/Omalgia/Lumbago/Sciatica Department 2, Sichuan Provincial Orthopedics Hospital, No. 132 West First Section First Ring Road,Wuhou District, Chengdu, 610041, Sichuan Province, China.

Background: Although the pathology of sciatica has been studied extensively, the transcriptional changes in the peripheral blood caused by sciatica have not been characterized. This study aimed to characterize the peripheral blood transcriptomic signature for sciatica.

Methods: We used a microarray to identify differentially expressed genes in the peripheral blood of patients with sciatica compared with that of healthy controls, performed a functional analysis to reveal the peripheral blood transcriptomic signature for sciatica, and conducted a network analysis to identify key genes that contribute to the observed transcriptional changes. Read More

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February 2021

[Meralgia paresthetica after prolonged prone position at the intensive care unit among COVID-19 patients. A case report].

Lakartidningen 2021 02 3;118. Epub 2021 Feb 3.

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Meralgia paresthetica (MP) is an entrapment syndrome that may cause loss of sensation, numbness, paresthesia and pain within the distribution of the lateral femoral cutaneous nerve. This condition is more common in persons with diabetes mellitus, obesity and in old age. MP has previously been described in patients that have undergone surgery in the prone position (PP) and in a case report of a patient with ARDS (Acute Respiratory Distress Syndrome) who was cared for in the intensive care unit (ICU). Read More

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February 2021