5,044 results match your criteria mucosa graft

Mucosal resurfacing of the suprastructure maxillectomy cavity using nasal cavity mucosa flaps.

Oral Oncol 2021 Apr 25:105289. Epub 2021 Apr 25.

Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea. Electronic address:

Objective: We analyzed clinical data of patients in which the suprastructure maxillectomy site was covered with nasal cavity mucosa flaps with or without free mucosa graft from the nasal septum, to determine the usefulness of this procedure.

Patients And Methods: A total of four edentulous patients who had the suprastructure maxillectomy site covered using nasal cavity mucosa flaps with or without free mucosa graft from the nasal septum between 2014 and 2020, were analyzed.

Results: All patients underwent suprastructure maxillectomy using the external approach. Read More

View Article and Full-Text PDF

The Impact of Preoperative Oral Health on Buccal Mucosa Graft Histology.

J Urol 2021 Apr 27:101097JU0000000000001829. Epub 2021 Apr 27.

Department of Urology, Columbia University Irving Medical Center, New York, New York.

Purpose: Previous studies have elucidated the unique macroscopic and histologic properties of buccal mucosa that make it a viable and durable graft for urethral augmentation. However, no prior literature has directly investigated the impact of preoperative oral health on these features.

Materials And Methods: We analyzed all consenting patients who underwent buccal mucosal graft (BMG) urethroplasty at our institution from 2018-2020. Read More

View Article and Full-Text PDF

Distal extension of palatal rugae as a limitation for donor soft tissue grafts in a Jordanian population: A cross-sectional study.

BMC Oral Health 2021 04 23;21(1):203. Epub 2021 Apr 23.

College of Dentistry, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, 11426, Saudi Arabia.

Background: The purpose of the cross sectional study was to investigate the distal extension of the rugae area in a Jordanian (Middle Eastern) population, as an anatomical limitation influencing the surgical decision of harvesting a palatal soft tissue graft. Factors that may influence or predict the extension were also assessed.

Methods: Sixty periodontally healthy participants (29 males and 31 females) were included. Read More

View Article and Full-Text PDF

The Palatal Fistula Closure Using Buccal Fat Graft After Palatoplasty for Cleft Palate: Two Case Reports.

Cleft Palate Craniofac J 2021 Apr 22:10556656211007000. Epub 2021 Apr 22.

Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Fistula recurrence is high after secondary follow-up operation to close the fistula after primary palatal surgery. Therefore, preventing fistula recurrence is important. Here, we describe the technique of closing palatal fistula after palatal surgery with a buccal fat graft in 2 cases. Read More

View Article and Full-Text PDF

Buccal Mucosa Graft Harvest in Children and Young Adults: Case Series and Harvest Technique.

Cureus 2021 Mar 14;13(3):e13884. Epub 2021 Mar 14.

Otolaryngology, State University of New York at Buffalo, Buffalo, USA.

Buccal mucosa is a great choice for urethroplasty for urethral stricture repair because of ease of harvesting, pliability of the graft, and minimal donor site morbidity. These procedures are performed at our institution as a combined case with Pediatric Otolaryngology and Urology. Harvesting buccal mucosal grafts in younger patients is more technically challenging due to limited oral cavity access and smaller area available for tissue harvest, but is able to be performed safely and with limited morbidity with the addition of parotid duct cannulation and use of retraction sutures to the graft harvest technique. Read More

View Article and Full-Text PDF

Eye amputation following lifitegrast treatment for ocular graft-versus-host disease: First case report.

J Fr Ophtalmol 2021 Apr 12. Epub 2021 Apr 12.

Ophthalmology department, University Hospital of Nice, 30, voie Romaine, 06000 Nice, France. Electronic address:

Graft-versus-host disease (GVHD) is a common complication in patients undergoing allogeneic stem cell transplantation for acute myeloblastic leukemia that could be very difficult to treat. Lifitegrast 5% (Xiidra@, Novartis), a new immunosuppressive eye drop, was recently approved by the FDA for the treatment of severe dry eye and is currently under review by the European Medicines Agency. In France, lifitegrast has been approved by the French authorities for temporary use in refractory dry eye syndrome resistant to tear substitutes and topical cyclosporine. Read More

View Article and Full-Text PDF

A new double graft technique in urethroplasty for complex urethral stenosis: preliminary findings.

Int Braz J Urol 2021 Jul-Aug;47(4):856-860

Clínica de Distúrbios do Trato Urinário, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brasil.

The management of complex urethral stenosis may involve different surgical techniques. As retraction of the graft may account for surgical failure, this risk increases in patients with more extensive stenosis requiring a graft of greater diameter. Although double grafts have already been used to maximize success in these cases, we propose a modified technique for urethroplasty with longitudinal urethral incision. Read More

View Article and Full-Text PDF

Effect of ridge preservation at molar extraction sites with severe periodontitis on the Schneiderian membrane thickness changes: a pilot study.

BMC Oral Health 2021 04 12;21(1):184. Epub 2021 Apr 12.

Department of Restorative Dentistry, University of Washington, Seattle, WA, USA.

Background: Information regarding the reaction of bone augmentation in terms to sinus mucosa thickness of periodontally compromised molar extraction sites is limited. This retrospective study aimed to analyze the effect of ridge preservation procedures following the extraction of molars with severe periodontitis on the healing pattern of adjacent maxillary sinus mucosal membranes.

Methods: Thirty-one periodontally compromised maxillary molar teeth either receiving ridge preservation (test group, n = 20) or undergoing spontaneous healing (control group, n = 11) were investigated. Read More

View Article and Full-Text PDF

Graft-versus-host disease prophylaxis with posttransplantation bendamustine (PTB) in patients with refractory acute leukemia: a dose-ranging study: Category of manuscript: Regular Manuscript.

Transplant Cell Ther 2021 Apr 9. Epub 2021 Apr 9.

RM Gorbacheva Research Institute, Pavlov University, Saint-Petersburg, Russian Federation. Electronic address:

Background: The prognosis of acute leukemia refractory to induction chemotherapy or immunotherapy is dismal. Salvage allogeneic hematopoietic stem cell transplantation (HSCT) is widely used option for these patients, but only 10-15% of patients are cured by the procedure. Preclinical studies indicate that substitution of posttransplantation cyclophosphomide (PTCY) with bendamustine (PTB) in a prophylaxis regimen may be associated with augmented graft-versus-leukemia (GVL) reaction. Read More

View Article and Full-Text PDF

Lingual mucosa graft ureteroplasty for ureteral stricture: a narrative review of the current literature.

Ann Palliat Med 2021 Mar 23. Epub 2021 Mar 23.

Department of Urology, Peking University First Hospital, Beijing, China; Institute of Urology, Peking University, Beijing, China; National Urological Cancer Center, Beijing, China.

Long proximal or middle ureteral strictures remain challenging conditions. Although ileal replacement of the ureter or renal autotransplantation are possible solutions for these problems, both present complexities and considerable morbidity. In recent years, many urologists have tended to use oral mucosal grafts to repair complex proximal or middle ureteral strictures and thereby avoid ileal replacement and renal autotransplantation. Read More

View Article and Full-Text PDF

[Application of three-staged paramedian forehead flap in reconstruction and repair of full-thickness nasal defect].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;56(4):374-380

Department of Maxillofacial Surgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

To evaluate the application of three-staged paramendian forehead flap technique in reconstruction of severe full-thickness nasal defect. Clinical data of 7 cases with nasal reconstruction by three-staged forehead flap technique in the First Affiliated Hospital of Xinjiang Medical University and HongKong University Shenzhen Hospital between June 2016 and October 2019 was retrospectively reviewed. All were males aged from 10 to 71 years. Read More

View Article and Full-Text PDF

De novo ulcerative colitis after kidney transplantation treated with infliximab.

CEN Case Rep 2021 Apr 7. Epub 2021 Apr 7.

Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-0072, Japan.

Diarrhea is a common complication in kidney transplant recipients. Common causes of diarrhea include infection, side effect from medication, rejection, and malignancy. A less common but important cause of diarrhea is de novo inflammatory bowel disease (IBD). Read More

View Article and Full-Text PDF

Periodontal Plastic Surgery for Reshaping the Mucogingival Junction Following Grafting Procedures: Case Reports.

Int J Periodontics Restorative Dent 2021 Mar-Apr;41(2):207-214

The present clinical and histologic case reports describe the periodontal plastic approaches used for the correction of gingival deformities following free gingival grafting (FGG) procedures. Five patients with poor esthetic and functional outcomes following soft tissue grafting voluntarily requested corrective treatment due to differences in color, texture, thickness, and mucogingival junction (MGJ) alignment between grafted and adjacent tissue, or because of food retention apical to the grafted site. Plastic surgical approaches included eliminating the thick borders the graft, aligning the MGJ, and reducing the excessive apicocoronal dimension of the graft. Read More

View Article and Full-Text PDF

Multi-Analytical Framework to Assess the In Vitro Swallowability of Solid Oral Dosage Forms Targeting Patient Acceptability and Adherence.

Pharmaceutics 2021 Mar 19;13(3). Epub 2021 Mar 19.

Aston Pharmacy School, College of Health and Life Sciences, Aston University, Birmingham B4 7ET, UK.

A lack of effective intervention in addressing patient non-adherence and the acceptability of solid oral dosage forms combined with the clinical consequences of swallowing problems in an ageing world population highlight the need for developing methods to study the swallowability of tablets. Due to the absence of suitable techniques, this study developed various in vitro analytical tools to assess physical properties governing the swallowing process of tablets by mimicking static and dynamic stages of time-independent oral transitioning events. Non-anatomical models with oral mucosa-mimicking surfaces were developed to assess the swallowability of tablets; an SLA 3D printed in vitro oral apparatus derived the coefficient of sliding friction and a friction sledge for a modified tensometer measured the shear adhesion profile. Read More

View Article and Full-Text PDF

Fabrication of Adipose-Derived Stem Cell-Based Self-Assembled Scaffold under Hypoxia and Mechanical Stimulation for Urethral Tissue Engineering.

Int J Mol Sci 2021 Mar 25;22(7). Epub 2021 Mar 25.

Centre for Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia Medical Centre, 12th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.

Long urethral strictures are often treated with autologous genital skin and buccal mucosa grafts; however, risk of hair ingrowth and donor site morbidity, restrict their application. To overcome this, we introduced a tissue-engineered human urethra comprising adipose-derived stem cell (ASC)-based self-assembled scaffold, human urothelial cells (UCs) and smooth muscle cells (SMCs). ASCs were cultured with ascorbic acid to stimulate extracellular matrix (ECM) production. Read More

View Article and Full-Text PDF

Multi-factorial analysis of recurrence and complications of lingual mucosa graft urethroplasty for anterior urethral stricture: Experience from a Chinese referral center.

Urology 2021 Mar 27. Epub 2021 Mar 27.

The Department of Urology, affiliated Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, China, 200233; Shanghai Eastern Institute of Urologic Reconstruction, Shanghai, China, 200233. Electronic address:

Objectives: To evaluate the risk factors that pertain to stricture recurrence and oral complications.

Methods: Patients with long segmented anterior urethral stricture who visited our hospital from 2009 to 2016 were treated with lingual mucosa graft (LMG) urethroplasty. The incidence of complications in all of 128 patients were evaluated. Read More

View Article and Full-Text PDF

Uretroplasty with oral mucosal graft in patients with anterior urethral stenosis. Comparative study with conventional treatment.

Cir Cir 2021 ;89(2):206-211

División de Proyectos Especiales en Salud, IMSS, Ciudad de México. México.

Antecedentes: El manejo con uretroplastía de la estenosis uretral es una opción quirúrgica fundamental, y comparar la uretroplastía con injerto de mucosa oral con la uretroplastía término-terminal tiene trascendencia para conocer la diferencia entre ambas técnicas.

Objetivo: Comparar la uretroplastía con injerto de mucosa oral con la uretroplastía término-terminal en pacientes con estenosis uretral tipo Jordan C, D y E.

MÉtodo: Cuasiexperimento realizado en pacientes con estenosis uretral anterior operados de uretroplastía con anastomosis término-terminal o con injerto de mucosa bucal. Read More

View Article and Full-Text PDF
January 2021

The Endonasal Endoscopic Management of Cerebrospinal Fluid Rhinorrhea.

Cureus 2021 Feb 20;13(2):e13457. Epub 2021 Feb 20.

Otolaryngology - Head and Neck Surgery, King Fahad Specialist Hospital, Dammam, SAU.

Introduction Cerebrospinal fluid (CSF) rhinorrhea is the result of a bony defect at the skull base with disruption of the arachnoid, dura mater, and sinonasal mucosa that leads to an active CSF leak and flow of clear fluid from the nose. The endoscopic repair of CSF leaks and skull defects have been used by an increasing number of surgeons and is the standard of care for repairing CSF leaks. Materials and methods We conducted a retrospective study of all cases of CSF leaks managed via the endonasal endoscopic approach from 2010 to 2020 at a tertiary referral hospital of King Fahad Specialist Hospital, Dammam (KFSH-D). Read More

View Article and Full-Text PDF
February 2021

Gut Microbiota Dysbiosis Associated with Persistent Fatigue in Hematopoietic Cell Transplantation Survivors.

Transplant Cell Ther 2021 Feb 27. Epub 2021 Feb 27.

Institute on Aging, University of Florida, Gainesville, Florida.

Fatigue is one of the most prevalent and distressing complications among hematopoietic stem cell transplantation (HCT) survivors, negatively affecting physical, social, and emotional domains of quality of life. Chronic systemic inflammation has been linked to alterations in nervous system activity and initiation of distressing symptoms, such as fatigue. Damage to gut mucosa due to alteration in gut microbiota (GM) composition and microbial translocation has been shown to increase systemic proinflammatory cytokines. Read More

View Article and Full-Text PDF
February 2021

Novel operative technique of advancement urethral meatoplasty utilizing buccal mucosa for Vulvar Paget's disease with urethral invasion: two case reports.

J Med Case Rep 2021 Mar 28;15(1):136. Epub 2021 Mar 28.

Department of Urology, The Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Background: Vulvar Paget's disease (VPD) is a rare malignant disorder originating in the external genitalia. It occasionally invades into urethral or vaginal mucosa of female, making surgical treatment more complicating. In case of urethral invasion of Paget's cells, systematic mapping biopsy of urethral mucosa is the standard of care to determine the range of surgical resection. Read More

View Article and Full-Text PDF

Lichen sclerosis-induced long segment anterior urethral stricture: The early outcome of one-stage repair using dorsolateral onlay buccal mucosa graft.

Urologia 2021 Mar 25:3915603211003396. Epub 2021 Mar 25.

Department of Urology, Sohag University Hospital, Sohag University, Sohag, Egypt.

Background: Substitution urethroplasty using buccal mucosal grafts can be performed by several approaches including ventral onlay graft, dorsal onlay graft, or ventral urethrotomy with dorsal inlay graft. Our study aims to evaluate the surgical outcome of dorsolateral buccal mucosal graft for long segment anterior urethral stricture >6 cm in patients with Lichen sclerosus (LS).

Methods: A retrospective study included patients who underwent repair for long segment anterior urethral stricture >6 cm due to LS between January 2013 and April 2019. Read More

View Article and Full-Text PDF

Buccal mucosa graft in surgical management of Peyronie's disease: Ultrasound features and clinical outcomes.

Arch Ital Urol Androl 2021 Mar 22;93(1):107-110. Epub 2021 Mar 22.

Urology Unit, Surgical Department, ASUR Marche Area Vasta 3, Macerata.

Introduction: Plaque incision and grafting represent the best surgical approach to the Peyronie's Disease (PD). The grafting procedures must be restricted to patients with normal preoperative status, excessive curvature and/or deformities. However, the ideal graft has not been identified yet. Read More

View Article and Full-Text PDF

Normal gastrointestinal tract inflammatory cells and review of select benign hematolymphoid proliferations.

Semin Diagn Pathol 2021 Feb 26. Epub 2021 Feb 26.

Department of Pathology, University of Virginia, 1215 Lee Street, Box 800214, Charlottesville, VA, United States. Electronic address:

The luminal gastrointestinal tract can be a site of robust immune response in which reactive lymphoproliferative processes can sometimes be difficult to distinguish from lymphoma. In this article, we review gastrointestinal tract normal resident inflammatory cells and common nonneoplastic lymphoproliferative responses with emphasis on their differential and links to lymphoma. Topics that are covered include lymphocytic esophagitis, gastric chronic inflammation, mucosa-associated lymphoid tissue, and ulceration, small intestinal lymphoid hyperplasia, celiac disease, microscopic colitis, inflammatory bowel disease, primary immunodeficiency, graft-versus-host disease, and anti-programmed cell death protein-1 effect. Read More

View Article and Full-Text PDF
February 2021

Perineal urethrostomy with combined buccal mucosal graft and skin flap after complete loss of anterior urethra.

IJU Case Rep 2021 Mar 3;4(2):92-94. Epub 2021 Jan 3.

Department of Urology Hyogo College of Medicine Nishinomiya Hyogo Japan.

Introduction: We report a novel perineal urethrostomy procedure for complete loss of anterior urethral tissue.

Case Presentation: A 74-year-old man had complete necrosis of the corpus spongiosum and corpora cavernosa after repeated transurethral surgical procedures. He had been managed with a suprapubic cystostomy tube for 10 years. Read More

View Article and Full-Text PDF

Free Mucosal Graft for Reconstruction after Nonfunctional Pituitary Adenoma Surgery.

Asian J Neurosurg 2020 Oct-Dec;15(4):946-951. Epub 2020 Oct 19.

Department of Neurosurgery, University Hospital La Paz, Madrid, Spain.

Background: In the search for an effective closure without nasosinusal morbidity, we have studied the efficacy of free mucosal graft as a reconstructive technique of the sellar floor after the resection of nonfunctioning pituitary adenomas (NFPA).

Methods: In 100 endonasal endoscopic surgeries, we analyzed the personal history, radiological and intraoperative aspects that could have an impact on the risk of postoperative cerebrospinal fluid (CSF) leak. They were divided into three groups: no mucosa flap/graft, mucosal free graft, and nasoseptal pedicled flap. Read More

View Article and Full-Text PDF
October 2020

Management of Peri-implant Mucositis of Multiple Osseointegrated Implants Using a Modified Free Gingival Graft "Punch Technique" in the Total Edentulous Area: A Case Report.

J Int Soc Prev Community Dent 2021 Jan-Feb;11(1):109-113. Epub 2021 Jan 30.

Postgraduate Department, Faculty of Dentistry, Universidad Peruana Cayetano Heredia, Lima, Peru.

The purpose of this case report was to describe a technique to modify the free gingival graft by perforations within the graft to guarantee a horizontal increase in the keratinized mucosa in the anteroinferior sector of a total edentulous mandible after osseointegration of previously placed dental implants in a hybrid prosthesis protocol. A 71-year-old male underwent free modified gingival graft surgery with perforations at the level of each implant. At 3 months, the mucosa appeared to be healthy and keratinized, especially at a horizontal level around the implants previously diagnosed with mucositis, providing the patient with satisfactory results. Read More

View Article and Full-Text PDF
January 2021

A Systematic Review of Randomized Controlled Trials Comparing Buccal Mucosal Graft Harvest Site Non-Closure Closure in Patients Undergoing Urethral Reconstruction.

World J Mens Health 2021 Feb 15. Epub 2021 Feb 15.

Department of Urology, University of Minnesota, Minneapolis, MN, USA.

Purpose: To assess the effects of buccal mucosal graft site non-closure versus closure on postoperative oral morbidity for male undergoing augmentation urethroplasty for urethral stricture.

Materials And Methods: We included randomized controlled trials. Inclusion criteria were male over the age of 18 with urethral stricture disease requiring reconstruction with buccal mucosal graft harvest. Read More

View Article and Full-Text PDF
February 2021

Comparison of Medial Underlay and Lateral Underlay Endoscopic Type I Tympanoplasty for Anterior Perforations of the Tympanic Membrane.

Otol Neurotol 2021 Mar 3. Epub 2021 Mar 3.

Department of Otorhinolaryngology and Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.

Objectives: To compare the outcomes of medial and lateral underlay endoscopic type I tympanoplasty for anterior tympanic membrane (TM) perforations.

Study Design: Retrospective chart review.

Setting: Tertiary care academic referral center. Read More

View Article and Full-Text PDF

Cryopreserved skin epithelial cell sheet combined with acellular amniotic membrane as an off-the-shelf scaffold for urethral regeneration.

Mater Sci Eng C Mater Biol Appl 2021 Mar 3;122:111926. Epub 2021 Feb 3.

Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Background: Autologous tissue transplantation for urethral repair is often limited and causes donor site complications. Here, a cryopreserved rabbit skin epithelial cell sheet (SEC) combined with an acellular amniotic membrane (AM) was used to repair rabbit urethral defects.

Methods: Abdominal skin was collected from 4-week-old New Zealand rabbits, and primary epithelial cells were extracted and cultured to form a cell sheet. Read More

View Article and Full-Text PDF