198 results match your criteria movement cpc

Cognitive deficit is correlated with sleep stability in insomnia: A cardiopulmonary coupling study.

Brain Behav 2021 May 7:e02068. Epub 2021 May 7.

Department of Neurology, Tianjin Medical University General Hospital Airport Site, Tianjin, China.

Objectives: To assess the correlation of cognitive function with sleep stability and depressive-anxious symptoms in insomnia patients.

Methods: Twenty-two insomnia patients with cognitive impairment (insomnia-CI), 21 insomnia patients with normal cognition (insomnia-CN), and 15 matched healthy control subjects (HCs) were enrolled and completed neuropsychological tests, the Hamilton Depression and Anxiety Scales (HAMD and HAMA), the Epworth Sleepiness Scale, the Pittsburgh Sleep Quality Index (PSQI),the Insomnia Severity Index (ISI), and the cardiopulmonary coupling (CPC) examination. Ratios of high-frequency coupling (HFC), low-frequency coupling (LFC), and very low-frequency coupling (VLFC) measured by CPC analysis represent stable sleep, unstable sleep, and wake/rapid eye movement (REM) sleep, respectively. Read More

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COVID-19 and heat waves: New challenges for healthcare systems.

Environ Res 2021 07 20;198:111153. Epub 2021 Apr 20.

Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Ziemssenstr. 1, 80336, Munich, Germany; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany.

Heat waves and Covid-19 overlap, as this pandemic continues into summer 2021. Using a narrative review, we identified overlapping risk groups and propose coping strategies. The high-risk groups for heat-related health problems as well as for high-risk COVID-19 groups overlap considerably (elderly with pre-existing health conditions). Read More

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Borealin directs recruitment of the CPC to oocyte chromosomes and movement to the microtubules.

J Cell Biol 2021 Jun;220(6)

Waksman Institute and Department of Genetics, Rutgers, the State University of New Jersey, Piscataway, NJ.

The chromosomes in the oocytes of many animals appear to promote bipolar spindle assembly. In Drosophila oocytes, spindle assembly requires the chromosome passenger complex (CPC), which consists of INCENP, Borealin, Survivin, and Aurora B. To determine what recruits the CPC to the chromosomes and its role in spindle assembly, we developed a strategy to manipulate the function and localization of INCENP, which is critical for recruiting the Aurora B kinase. Read More

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Toward Biofabrication of Resorbable Implants Consisting of a Calcium Phosphate Cement and Fibrin-A Characterization In Vitro and In Vivo.

Int J Mol Sci 2021 Jan 26;22(3). Epub 2021 Jan 26.

Department of Oral and Maxillofacial Surgery Charité, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Augustenburger Platz 1, 13353 Berlin, Germany.

Cleft alveolar bone defects can be treated potentially with tissue engineered bone grafts. Herein, we developed novel biphasic bone constructs consisting of two clinically certified materials, a calcium phosphate cement (CPC) and a fibrin gel that were biofabricated using 3D plotting. The fibrin gel was loaded with mesenchymal stromal cells (MSC) derived from bone marrow. Read More

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January 2021

Multicomponent Analysis of Sleep Using Electrocortical, Respiratory, Autonomic and Hemodynamic Signals Reveals Distinct Features of Stable and Unstable NREM and REM Sleep.

Front Physiol 2020 3;11:592978. Epub 2020 Dec 3.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States.

A new concept of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep is proposed, that of multi-component integrative states that define stable and unstable sleep, respectively, NREM, NREM REM, and REM. Three complementary data sets are used: obstructive sleep apnea (20), healthy subjects (11), and high loop gain sleep apnea (50). We use polysomnography (PSG) with beat-to-beat blood pressure monitoring, and electrocardiogram (ECG)-derived cardiopulmonary coupling (CPC) analysis to demonstrate a bimodal, rather than graded, characteristic of NREM sleep. Read More

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December 2020

[The epidemic, prophylaxis and treatment of cholera in Su-Wan Liberated Area in 1946].

C Y Xu H J Tao W Peng

Zhonghua Yi Shi Za Zhi 2020 Sep;50(5):302-306

Fusion Media Center of Rugao in Jiangsu, Rugao 226500; China.

Rugao and Haian belonging to First Branch of Su-Wan Liberated Area found fulminant cholera in 1946. The fulminant cholera spread throughout the Su-Wan Liberated Area in a short period of time. Thus, local mass and military led by CPC actively launched the Movement of Epidemic Prevention. Read More

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September 2020

Cortical Projection From the Premotor or Primary Motor Cortex to the Subthalamic Nucleus in Intact and Parkinsonian Adult Macaque Monkeys: A Pilot Tracing Study.

Front Neural Circuits 2020 26;14:528993. Epub 2020 Oct 26.

Department of Neurosciences and Movement Sciences, Faculty of Science and Medicine, Section of Medicine, Fribourg Cognition Center, Platform of Translational Neurosciences (PTN), Swiss Primate Competence Center for Research (SPCCR), University of Fribourg, Fribourg, Switzerland.

Besides the main cortical inputs to the basal ganglia, the corticostriatal projection, there is another input the corticosubthalamic projection (CSTP), terminating in the subthalamic nucleus (STN). The present study investigated and compared the CSTPs originating from the premotor cortex (PM) or the primary motor cortex (M1) in two groups of adult macaque monkeys. The first group includes six intact monkeys, whereas the second group was made up of four monkeys subjected to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication producing Parkinson's disease (PD)-like symptoms and subsequently treated with an autologous neural cell ecosystem (ANCE) therapy. Read More

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October 2020

Advanced in Vitro Experimental Models for Tissue Engineering-based Reconstruction of a 3D Dentin/pulp Complex: a Literature Review.

Stem Cell Rev Rep 2021 Jun 3;17(3):785-802. Epub 2020 Nov 3.

Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki (A.U.Th), GR-54124, Thessaloniki, Greece.

Objective: Experimental procedures have been used to monitor cellular responses at the dentin/pulp interface. Aiming to divert from in vivo studies and oversimplified two-dimensional assays, three-dimensional (3D) models have been developed. This review provides an overview of existing literature, regarding 3D in vitro dentin/pulp reconstruction. Read More

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A Computational Framework to Study the Effect of Acupuncture on Obesity by Integrating Multiple Levels of Data.

Biomed Res Int 2020 16;2020:8513860. Epub 2020 Oct 16.

Chifeng Municipal Hospital, Chifeng, China.

In this study, we evaluated the efficacy of acupuncture in the treatment of obesity by a computational framework integrating randomized controlled trials published in China and abroad. Specifically, clinical trial documents published on CNKI, VIP, Wanfang, PubMed, Embase, and the Cochrane Library from 2007-2017 were downloaded and analyzed using Stata 15.1 system. Read More

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Validation of a finite element model with six-year-old child anatomical characteristics as specified in Euro NCAP Pedestrian Human Model Certification (TB024).

Comput Methods Biomech Biomed Engin 2021 Jan 2;24(1):76-90. Epub 2020 Sep 2.

Medical Imaging Department, Tianjin Children's Hospital, Tianjin, China.

Accident statistics show that more than 80% of car-to-pedestrian collisions (CPC) occur when pedestrians cross the road. It is very important to establish a finite element model with natural walking posture to study the kinematics and injury mechanism of pedestrians. In this study, a finite element model of six-year-old child pedestrian is developed with detailed anatomical characteristics and posture parameters as specified in Euro NCAP Pedestrian Human Model Certification (TB024). Read More

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January 2021

Localization of tomato () R3 MYB protein encoded by in roots.

Plant Signal Behav 2020 10 2;15(10):1800198. Epub 2020 Aug 2.

Graduate School of Integrated Sciences for Life, Hiroshima University , Higashi-Hiroshima, Japan.

CAPRICE (CPC), an R3-type MYB transcription factor, is known to promote root hair differentiation in the root epidermis of . CPC moves from non-hair cells to adjacent hair-forming cells. In contrast, we have previously shown that there is no movement of the CPC homologs, ENHANCER OF TRY AND CPC 1, 2, and 3 (ETC1, 2, and 3), and TRYPTICHON (TRY) between root epidermal cells. Read More

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October 2020

c-Phycocyanin primed silver nano conjugates: Studies on red blood cell stress resilience mechanism.

Colloids Surf B Biointerfaces 2020 Oct 25;194:111211. Epub 2020 Jun 25.

Department of Applied Physiology, School of Medicine, University of Miyazaki, Miyazaki, 889 1692, Japan.

Green synthesis of metal-encased nutraceutical nano-hybrids has been a target for research over the last few years. In the present investigation, we have reported temperature dependent facile synthesis of silver nanoparticles using FDA approved c phycocyanin (cPC). The cPC conjugated silver nanoparticles (AgcPCNPs) were characterized by TEM, Zeta Potential, UV-vis, XPS, FTIR, and CD Spectroscopy. Read More

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October 2020

Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival.

J Mol Histol 2020 Aug 22;51(4):385-400. Epub 2020 Jun 22.

Department of Anatomy-Histology-Embryology, Medical School, University of Patras, 26500, Patras, Greece.

Integrin-linked kinase (ILK) forms a heterotrimeric protein complex with PINCH and PARVIN (IPP) in Focal Adhesions (FAs) that acts as a signaling platform between the cell and its microenvironment regulating important cancer-related functions. We aimed to elucidate the role of ILK in lung adenocarcinoma (LUADC) focusing on a possible link with KRAS oncogene. We used immunohistochemistry on human tissue samples and KRAS-driven LUADC in mice, analysis of large scale publicly available RNA sequencing data, ILK overexpression and pharmacological inhibition as well as knockdown of KRAS in lung cancer cells. Read More

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A System for the Detection of Persons in Intelligent Buildings Using Camera Systems-A Comparative Study.

Sensors (Basel) 2020 Jun 23;20(12). Epub 2020 Jun 23.

Department of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, VSB-Technical University of Ostrava, 17. listopadu 15, 708 33 Ostrava, Czech Republic.

This article deals with the design and implementation of a prototype of an efficient Low-Cost, Low-Power, Low Complexity-hereinafter (L-CPC) an image recognition system for person detection. The developed and presented methods for processing, analyzing and recognition are designed exactly for inbuilt devices (e.g. Read More

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Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.

J Cell Biol 2020 07;219(7)

Department of Biochemistry, University of Oxford, Oxford, UK.

The Aurora B chromosomal passenger complex (CPC) is a conserved regulator of mitosis. Its functions require localization first to the chromosome arms and then centromeres in mitosis and subsequently the central spindle in anaphase. Here, we analyze the requirements for core CPC subunits, survivin and INCENP, and the mitotic kinesin-like protein 2 (MKLP2) in targeting to these distinct localizations. Read More

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Plantar Flexion-Induced Entrapment of the Dorsalis Pedis Artery in a Teenaged Cross-Country Runner.

Ann Vasc Surg 2021 Jan 22;70:213-218. Epub 2020 Apr 22.

Department of Vascular Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO. Electronic address:

Background: Symptomatic peripheral artery disease of the lower extremity rarely affects young adults and, when present, typically has a nonatherosclerotic etiology. Anatomical variants have manifested as symptomatic foot ischemia in four cases in the literature. We describe the case of a 17-year-old girl presenting with foot pain upon plantar flexion due to dynamic dorsalis pedis (DP) artery entrapment by fibrous bands and the extensor hallucis brevis (EHB) tendon. Read More

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January 2021

The biomechanical impact of hip movement on iliofemoral venous anatomy and stenting for deep venous thrombosis.

J Vasc Surg Venous Lymphat Disord 2020 11 19;8(6):953-960. Epub 2020 Apr 19.

Department of Vascular Surgery, Guy's and St Thomas' NHS Trust, King's College London, London, United Kingdom.

Background: Stenting of the iliofemoral vein may be an effective treatment to improve post-thrombotic symptoms. Iliofemoral vein stents have requirements different from those of lower extremity artery stents, and there is a paucity of literature regarding the biomechanical motion of the iliofemoral vein.

Methods: In a novel cadaveric model, stents were bilaterally inserted into the veins in the iliofemoral region. Read More

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November 2020

Down-regulation of FTO promotes proliferation and migration, and protects bladder cancer cells from cisplatin-induced cytotoxicity.

BMC Urol 2020 Apr 16;20(1):39. Epub 2020 Apr 16.

Department of Urology, The Second Hospital of Dalian Medical University, 467 Zhongshan Road, Shahekou, Dalian, 116023, China.

Background: FTO is known to be associated with body mass and obesity in humans and its over-expression affects the energy metabolism of cancer cells. The aim of the present study is to investigate the biological role of FTO in human bladder urothelial carcinoma.

Methods: PCR and western blotting are used to measure the levels of FTO in both tissues and cell lines (5637, T24, TCCSUP) of human bladder urothelial carcinoma. Read More

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Does disability level impact the relationship of muscle strength to walking performance in people with multiple sclerosis? a cross-sectional analysis.

Mult Scler Relat Disord 2020 Jul 13;42:102052. Epub 2020 Mar 13.

Physical Therapy Program, Department of Physical Medicine and Rehabilitation, School of Medicine, University of Colorado Denver, Aurora, CO.

Background And Purpose: Strength training can improve muscle weakness in people with multiple sclerosis (MS), but does not consistently improve walking. Disability level may impact the relationship of muscle weakness and walking performance in people with MS, but few studies have investigated the impact of disability on the relationship of strength and walking. The purpose of this study was to compare the relationships of strength in lower body and trunk muscles to walking performance between mild and moderate disability groups in people with MS. Read More

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[Cardiopulmonary coupling analysis in diagnosis of sleep disorders].

Zhonghua Yi Xue Za Zhi 2020 Mar;100(11):817-822

Department of Neurology (Sleep Disorders), the Affiliated Chaohu Hospital of Anhui Medical University, the Sleep Medicine Institute, Anhui Medical University, Hefei 238000, China.

To compare diagnostic consistency for chronic insomnia (CI) and obstructive sleep apnea (OSA) between cardiopulmonary coupling (CPC) and polysomnographm (PSG). Two hundred and twenty-one patients were enrolled from the Department of Sleep Disorders, Chaohu Hospital affiliated to Anhui Medical University from July 2018 to December 2019, and monitored with overnight CPC and PSG simultaneously. According to clinical representations and PSG results, there were 88 males and 80 females with CI and OSA, including chronic insomnia (CI group, 93 cases), OSA (OSA group, 36 cases) and comorbid OSA with CI (COI group, 39 cases). Read More

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Biallelic variants in encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility.

J Med Genet 2020 10 11;57(10):708-716. Epub 2020 Mar 11.

Univ. Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Team Genetics Epigenetics and Therapies of Infertility, Grenoble, France

Background: Multiple morphological abnormalities of the flagella (MMAF) consistently lead to male infertility due to a reduced or absent sperm motility defined as asthenozoospermia. Despite numerous genes recently described to be recurrently associated with MMAF, more than half of the cases analysed remain unresolved, suggesting that many yet uncharacterised gene defects account for this phenotype METHODS: Exome sequencing was performed on 167 infertile men with an MMAF phenotype. Immunostaining and transmission electron microscopy (TEM) in sperm cells from affected individuals were performed to characterise the ultrastructural sperm defects. Read More

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October 2020

Acute Exercise in Hypobaric Hypoxia Attenuates Endothelial Shedding in Subjects Unacclimatized to High Altitudes.

Front Physiol 2019 4;10:1632. Epub 2020 Feb 4.

Exercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zürich, Zurich, Switzerland.

Travel of unacclimatized subjects to a high altitude has been growing in popularity. Changes in endothelial shedding [circulating endothelial cells (ECs)] and hematopoietic stem and progenitor cells (CPCs) during physical exercise in hypobaric hypoxia, however, are not well understood. We investigated the change in ECs and CPCs when exposed to high altitude, after acute exercise therein, and after an overnight stay in hypobaric hypoxia in 11 healthy unacclimatized subjects. Read More

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February 2020

Pseudoatrial Flutter: When the Problem Lies Outside the Heart.

Clin Pract Cases Emerg Med 2020 Feb 23;4(1):109-110. Epub 2020 Jan 23.

Clinica Luganese, Via Moncucco, Department of Emergency Medicine, Lugano, Switzerland.

Electrocardiogram (ECG) artifacts are a common problem in emergency medicine. Generally these artifacts are induced by movement disorders, which generate electrical interference with the ECG recording. If these disorders are not promptly recognized, consequences can lead to hospitalization and execution of unnecessary diagnostic tests, thereby increasing the costs and clinical risks such as nosocomial infections and thromboembolism. Read More

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February 2020

Increased Gene Expression of RUNX2 and SOX9 in Mesenchymal Circulating Progenitors Is Associated with Autophagy during Physical Activity.

Oxid Med Cell Longev 2019 15;2019:8426259. Epub 2019 Oct 15.

Department of Medicine, University of Verona, Italy.

Lack of physical exercise is considered an important risk factor for chronic diseases. On the contrary, physical exercise reduces the morbidity rates of obesity, diabetes, bone disease, and hypertension. In order to gain novel molecular and cellular clues, we analyzed the effects of physical exercise on differentiation of mesenchymal circulating progenitor cells (M-CPCs) obtained from runners. Read More

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Circulating adult stem and progenitor cell numbers-can results be trusted?

Stem Cell Res Ther 2019 10 17;10(1):305. Epub 2019 Oct 17.

Exercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.

Background: Within the last years, the interest in physical exercise as non-invasive stimulus influencing circulating hematopoietic stem and progenitor cell (CPC) concentrations has constantly grown. Cell estimates are often derived by determining the subgroup of CPC as percent lymphocytes (LYM) or mononuclear cells (MNC) via flow cytometry and back calculation over whole blood (WB) cell counts. However, results might depend on the used cell isolation technique and/or gating strategy. Read More

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October 2019

Point-of-Care Ultrasound-Directed Evaluation of Elbow Effusion.

Clin Pract Cases Emerg Med 2019 Aug 22;3(3):286-288. Epub 2019 Jul 22.

Geisinger Medical Center, Department of Emergency Medicine, Danville, Pennsylvania.

A 53-year-old male presented with pain in the right elbow that was sudden in onset and progressively worsening over approximately eight hours. The pain was exacerbated with any movement of the elbow. Of note, he had been recently admitted for robotic prostatectomy and had a prolonged hospital stay requiring a course of antibiotics. Read More

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Dietary saturated fat and low-grade inflammation modified by accelerometer-measured physical activity in adolescence: results from the GINIplus and LISA birth cohorts.

BMC Public Health 2019 Jun 25;19(1):818. Epub 2019 Jun 25.

Institute of Epidemiology, Helmholtz Zentrum München, Institute of Epidemiology - German Research Centre for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

Background: Saturated fatty acids (SFA) have been reported to promote inflammation. Nevertheless, evidence linking dietary SFA and low-grade inflammation in adolescents is scarce and inconsistent. The modulatory role of physical activity (PA) on fat metabolism and inflammation may provide a potential explanation. Read More

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Corticotectal Projections From the Premotor or Primary Motor Cortex After Cortical Lesion or Parkinsonian Symptoms in Adult Macaque Monkeys: A Pilot Tracing Study.

Front Neuroanat 2019 22;13:50. Epub 2019 May 22.

Section of Medicine, Department of Neurosciences and Movement Sciences, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.

The corticotectal projections, together with the corticobulbar (corticoreticular) projections, work in parallel with the corticospinal tract (CST) to influence motoneurons in the spinal cord both directly and indirectly the brainstem descending pathways. The tectospinal tract (TST) originates in the deep layers of the superior colliculus. In the present study, we analyzed the corticotectal projections from two motor cortical areas, namely the premotor cortex (PM) and the primary motor cortex (M1) in eight macaque monkeys subjected to either a cortical lesion of the hand area in M1 ( = 4) or Parkinson's disease-like symptoms PD ( = 4). Read More

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Fluorine-free Superhydrophobic and Conductive Rubber Composite with Outstanding Deicing Performance for Highly Sensitive and Stretchable Strain Sensors.

ACS Appl Mater Interfaces 2019 May 1;11(19):17774-17783. Epub 2019 May 1.

School of Chemistry and Chemical Engineering , Yangzhou University , Yangzhou , Jiangsu 225002 , China.

Conductive polymer composite (CPC) based strain sensor due to its lightweight, tunable electrical conductivity, and easy processing has promising application in wearable electronics. However, it is still challenging to develop the CPC strain sensors with excellent stretchability, sensitivity, durability, anticorrosion, and deicing performance. Herein, a facile method is proposed to prepare fluorine-free superhydrophobic and highly conductive rubber composite. Read More

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