Int J Dev Neurosci 2021 Apr 24;81(2):209-219. Epub 2021 Jan 24.
National Health Commission, Key Laboratory of Birth Defect Prevention, Henan Scientific and Technical Institute of Reproductive Health, Zhengzhou, China.
Objectives: In order to understand the relationships between neocortical lamination and cell cycle, various cells, such as neural stem cell, migrating postmitotic neuron, Cajal-Retzius (CR) cell, and mature pyramidal cell in various cell phases were investigated in mouse cortices.
Methods: With mouse neocortex and hippocampus, the immunofluorescent labeling, BrdU assay, and DiI tracing technique were implemented in the study.
Results: (1) During mouse development, the neocortex expressed different proteins, such as FOXP2, CDP, and Nestin, which could be used as the markers for cortical lamination. Read More