480 results match your criteria moulds tested

Introducing 3D printed models of the upper urinary tract for high-fidelity simulation of retrograde intrarenal surgery.

3D Print Med 2021 Jun 7;7(1):15. Epub 2021 Jun 7.

Urology Unit, Policlinico Tor Vergata Foundation, Viale Oxford 81, 00133, Rome, Italy.

Purpose: Training in retrograde intrarenal surgery for the treatment of renal stone disease is a challenging task due to the unique complexity of the procedure. This study introduces a series of 3D printed models of upper urinary tract and stones designed to improve the training process.

Methods: Six different models of upper urinary tract were algorithmically isolated, digitally optimized and 3D printed from real-life cases. Read More

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Antimicrobial Activity of First-in-Class Antifungal, Manogepix, and Comparator Agents Testing against Contemporary Invasive Fungal Isolates from an International Surveillance Program (2018-2019): In Vitro Activity of Manogepix against Fungal Isolates.

J Glob Antimicrob Resist 2021 May 26. Epub 2021 May 26.

JMI Laboratories, North Liberty, IA, USA.

Objectives: Manogepix, the active moiety of the prodrug fosmanogepix, is a novel antifungal with activity against major fungal pathogens including Candida (except C. krusei), Aspergillus, and difficult-to-treat/rare moulds. We tested manogepix and comparators against 2,669 contemporary (2018-2019) fungal isolates collected from 82 medical centers located in North America (42. Read More

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Diversity of yeasts and moulds in dairy products from Umbria, central Italy.

J Dairy Res 2021 May 14;88(2):217-220. Epub 2021 May 14.

Medicina Veterinaria, Laboratorio di Ispezione degli Alimenti di Origine Animale, Università degli Studi di Perugia, 06126, Perugia, Italy.

In this research communication we report on the diversity of yeast and mould species in 69 samples of milk and different dairy products from three plants located in Umbria, central Italy. Isolates were characterised both macroscopically and microscopically and then identified by PCR and genome sequencing of the ITS region and the D1-D2 domain of the large-subunit rRNA gene for filamentous fungi and yeasts, respectively. Out of the 69 samples analysed, 51 (73. Read More

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Microbiological Safety and Sensory Quality of Cultivated Mushrooms (, and ) at Retail Level and Post-Retail Storage.

Foods 2021 Apr 9;10(4). Epub 2021 Apr 9.

Unit of Food Microbiology, Institute of Food Safety, Food Technology and Veterinary Public Health, University of Veterinary Medicine, 1210 Vienna, Austria.

In this study, the microbiological and sensory quality of cultivated mushrooms ( and and ) available at the Austrian retail level were determined. Aerobic mesophilic bacteria (AMC), (EB), (PS), lactic acid bacteria (LAB), yeast, moulds and presumptive were enumerated at the day of purchase and after storage at 4 °C for 7 or 12 days. Additionally, the presence of spp. Read More

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Phosphonates enantiomers receiving with fungal enzymatic systems.

Microb Cell Fact 2021 Apr 7;20(1):81. Epub 2021 Apr 7.

Department of Biochemistry, Molecular Biology and Biotechnology, Laboratory of Biotechnology, Wrocław University of Science and Technology, Wrocław, Poland.

Background: Phosphonates derivatives are in the area of interests because of their unique chemical-physical features. These compounds manifest variety of biological interactions within the sensitive living cells, including impact on particular enzymes activities. Biological "cause and effect" interactions are based upon the specific matching between the structures and/or compounds and this is usually the result of proper optical configurations of particular chiral moieties. Read More

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Essential oils and their components in combating fungal pathogens of animal and human skin.

J Mycol Med 2021 Jun 30;31(2):101118. Epub 2021 Jan 30.

The Łukasiewicz Research Network - Institute of Industrial Organic Chemistry, Department of Chemical Technology and Biotechnology, Annopol 6, 03-236 Warsaw, Poland.

Objective: The most common problems of modern medicine include fungal infections of the skin and its appendages caused by dermatomycetes, yeast-like fungi and moulds. Due to toxicity of pharmacological fungicides and promotion of ecology, natural substances with high antifungal properties are sought. Essential oils and their components show potential in this regard. Read More

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Antifungal susceptibility of clinical mould isolates in New Zealand, 2001-2019.

Pathology 2021 Jan 28. Epub 2021 Jan 28.

New Zealand Mycology Reference Laboratory, LabPlus, Auckland City Hospital, Auckland, New Zealand.

The objective of this study was to review the antifungal susceptibility of clinical mould isolates performed by the New Zealand Mycology Reference Laboratory. Isolates were either local or referred for testing from other New Zealand laboratories. All isolates were tested by the broth colorimetric microdilution method, Sensititre YeastOne (SYO). Read More

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January 2021

Ecophysiology of Penicillium expansum and patulin production in synthetic and olive-based media.

Fungal Biol 2021 Feb 21;125(2):95-102. Epub 2019 Aug 21.

Centro de Investigação de Montanha (CIMO), ESA, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal. Electronic address:

Olives and their derivatives, in particular olive oil, represent one of the most significant agricultural products in the Mediterranean basin. Storage under inadequate conditions poses serious problems concerning fungal contamination, with consequent defects and potential mycotoxin production in olives and olive oils. Penicillium expansum represents one of the most significant postharvest pathogens in several fruits, including olives. Read More

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February 2021

Antimicrobial Activity of Lipopeptide Biosurfactants Against Foodborne Pathogen and Food Spoilage Microorganisms and Their Cytotoxicity.

Front Microbiol 2020 11;11:561060. Epub 2021 Jan 11.

Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading, United Kingdom.

Lipopeptide biosurfactants produced by sp. were assessed regarding their antimicrobial activity against foodborne pathogenic and food spoilage microorganisms. Both Gram-positive and Gram-negative bacteria were found not to be susceptible to these lipopeptides. Read More

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January 2021

Optimizing the structure of (salicylideneamino)benzoic acids: Towards selective antifungal and anti-staphylococcal agents.

Eur J Pharm Sci 2021 Apr 22;159:105732. Epub 2021 Jan 22.

Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

An increasing resistance of human pathogenic bacteria and fungi has become a global health problem. Based on previous reports of 4-(salicylideneamino)benzoic acids, we designed, synthesised and evaluated their me-too analogues as potential antimicrobial agents. Forty imines derived from substituted salicylaldehydes and aminobenzoic acids, 4-aminobenzoic acid esters and 4-amino-N-phenylbenzamide were designed using molecular hybridization and prodrug strategies. Read More

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Development and Evaluation of a 3D-Printed Adult Proximal Tibia Model for Simulation Training in Intraosseous Access.

Cureus 2020 Dec 20;12(12):e12180. Epub 2020 Dec 20.

Emergency Medicine, Carbonear General Hospital, Carbonear, CAN.

Intraosseous infusion remains an underutilized technique for obtaining vascular access in adults, despite its potentially life-saving benefits in trauma patients and those presenting to the emergency department. There is a scarcity of cost-effective, anatomically correct trainers to improve physician confidence and competency in this skill. The purpose of this report is to describe the development and evaluation of a three-dimensional (3D) printed Adult Proximal Intraosseous (IO) Tibia task trainer for simulation-based medical education. Read More

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December 2020

Silver-109/Silver/Gold Nanoparticle-Enhanced Target Surface-Assisted Laser Desorption/Ionisation Mass Spectrometry-The New Methods for an Assessment of Mycotoxin Concentration on Building Materials.

Toxins (Basel) 2021 Jan 9;13(1). Epub 2021 Jan 9.

Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańców Warszawy Ave., 35-959 Rzeszów, Poland.

This study aimed to detect and quantify mycotoxins on building materials using innovative laser mass spectroscopy methods-silver-109/silver/gold nanoparticle-enhanced target surface-assisted laser desorption/ionisation mass spectrometry (AgNPs, AgNPs and AuNPs SALDI). Results from SALDI-type methods were also compared with commonly used matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. Standards of seven moulds mycotoxin in a final concentration of 100 µg/mL for patulin, citrinin, 3-nitropropionic acid, alternariol and 20 µg/mL for sterigmatocystin, cyclopiazonic acid, roquefortine C in the mixture were tested in pure solutions and after extraction from the plasterboards. Read More

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January 2021

In vitro activity of the novel antifungal olorofim against dermatophytes and opportunistic moulds including Penicillium and Talaromyces species.

J Antimicrob Chemother 2021 Apr;76(5):1229-1233

Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.

Objectives: Olorofim is a novel antifungal agent with in vitro activity against Aspergillus and other opportunistic moulds. We investigated the in vitro activity of olorofim against a range of filamentous fungi comprising isolates of Aspergillus species, Scedosporium species, Alternaria alternata, dermatophytes, including terbinafine- and multidrug-resistant Trichophyton species, and Penicillium/Talaromyces species originating from patients in North India.

Methods: Antifungal susceptibility of olorofim was tested against 241 mould isolates of Penicillium/Talaromyces species, Trichophyton species, A. Read More

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Efficient Reduction of Food Related Mould Spores on Surfaces by Hydrogen Peroxide Mist.

Foods 2020 Dec 28;10(1). Epub 2020 Dec 28.

Nofima-Norwegian Institute of Food, Fisheries and Aquaculture Research, P.O. Box 210, N-1431 Aas, Norway.

The aim of the study was to evaluate the fungicidal effect of a HO mist generating system for disinfection of spores of six food-related moulds (, , , , , and ) dried on stainless steel. Exposure to HO mist for 2 or 4 h lead to >3 log reduction in mould spores in the majority of the tests. The presence of the soils 2% skim milk or 3% BSA did not significantly alter the fungicidal effect, while the presence of raw meat juice had an adverse fungicidal effect against and in two out of three tests. Read More

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December 2020

Oral cysteamine as an adjunct treatment in cystic fibrosis pulmonary exacerbations: An exploratory randomized clinical trial.

PLoS One 2020 28;15(12):e0242945. Epub 2020 Dec 28.

NovaBiotics Ltd, Aberdeen, United Kingdom.

Background: Emerging data suggests a possible role for cysteamine as an adjunct treatment for pulmonary exacerbations of cystic fibrosis (CF) that continue to be a major clinical challenge. There are no studies investigating the use of cysteamine in pulmonary exacerbations of CF. This exploratory randomized clinical trial was conducted to answer the question: In future pivotal trials of cysteamine as an adjunct treatment in pulmonary exacerbations of CF, which candidate cysteamine dosing regimens should be tested and which are the most appropriate, clinically meaningful outcome measures to employ as endpoints?

Methods And Findings: Multicentre double-blind randomized clinical trial. Read More

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January 2021

Antifungal Activity of Polyoxometalate-Ionic Liquids on Historical Brick.

Molecules 2020 Dec 1;25(23). Epub 2020 Dec 1.

Instituto de Nanociencia y Materiales de Aragón (INMA), Consejo Superior de Investigaciones Científicas-Universidad de Zaragoza, 50009 Zaragoza, Spain.

Moulds inhabiting mineral-based materials may cause their biodeterioration, contributing to inestimable losses, especially in the case of cultural heritage objects and architectures. Fungi in mouldy buildings may also pose a threat to human health and constitute the main etiological factor in building related illnesses. In this context, research into novel compounds with antifungal activity is of high importance. Read More

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December 2020

Allergenicity at component level of sub-pollen particles from different sources obtained by osmolar shock: A molecular approach to thunderstorm-related asthma outbreaks.

Clin Exp Allergy 2021 Feb 26;51(2):253-261. Epub 2021 Jan 26.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano, Italy.

Background: The so-called "thunderstorm asthma" (TA) is an uncommon but dramatic outbreak of asthma attacks occurring during a thunderstorm in the pollen and moulds season. Mechanisms which make the pollen able to enter the deeper airways and provoke severe asthma symptoms are still unclear.

Objective: To test the hypothesis that sub-pollen particles (SPPs) originated from the rupture by an osmotic shock of pollen associated with TA contain allergens. Read More

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February 2021

Plant-based proteinaceous snacks: Effect of fermentation and ultrasonication on end-product characteristics.

Food Sci Nutr 2020 Sep 3;8(9):4746-4756. Epub 2020 Aug 3.

Lithuanian University of Health Sciences Kaunas Lithuania.

The study aimed at the development of a sufficient technology to improve sensory, textural, physical, and microbiological properties of peas snacks (Ps) using solid-state fermentation (SSF) and submerged fermentation (SMF) with two different lactic acid bacteria (LAB) strains ( LUHS210 and LUHS245) for 24 hr and ultrasonication (10, 20, and 30 min). To ensure safety of the used technologies, microbiological characteristics and biogenic amines (BAs) content in treated Ps were analyzed. Additionally, a different salt content (3. Read More

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September 2020

Antifungal activity of Euphorbia species against moulds responsible of cereal ear rots.

J Appl Microbiol 2021 Apr 6;130(4):1285-1293. Epub 2020 Oct 6.

LABIFITO, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, San Miguel de Tucumán, Argentina.

Aims: This work aimed to identify secondary metabolites from aerial parts of Euphorbia species functional for control of toxigenic Fusarium species responsible of cereal grain rots.

Methods And Results: Aerial parts of Euphorbia serpens, Euphorbia schickendantzii and Euphorbia collina were sequentially extracted with hexane, ethyl acetate and methanol. The extracts were tested against strains of Fusarium verticillioides and Fusarium graminearum by microdilution tests. Read More

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Determination of Fungi and Multi-Class Mycotoxins in and Herbal Teas and Dietary Exposure Assessment.

Toxins (Basel) 2020 08 29;12(9). Epub 2020 Aug 29.

Institute of Food Safety, Animal Health and Environment "BIOR", Riga LV-1076, Latvia.

In this paper, a study of fungal and multi-mycotoxin contamination in 140 and 26 herbal teas marketed in Latvia is discussed. The analysis was performed using two-dimensional liquid chromatography with time-of-flight mass spectrometry (2D-LC-TOF-MS) and MALDI-TOF-MS. In total, 87% of the tea samples tested positive for 32 fungal species belonging to 17 genera, with the total enumeration of moulds ranging between 1. Read More

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Introduction of a bead beating step improves fungal DNA extraction from selected patient specimens.

Int J Med Microbiol 2020 Sep 5;310(6):151443. Epub 2020 Aug 5.

Department of Haematology, Oncology and Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany.

In immunocompromised patients a colonisation with fungi carries the risk to develop serious invasive fungal infection. An early detection is therefore important, but not optimal hitherto. Fortunately, molecular genetic methods have increased the sensitivity of fungal detection and limited the time, until results are available. Read More

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September 2020

Modeling the inactivation of Aspergillus fischeri and Paecilomyces niveus ascospores in apple juice by different ultraviolet light irradiances.

Int J Food Microbiol 2020 Nov 25;333:108773. Epub 2020 Jun 25.

Federal University of Santa Catarina, Department of Chemical Engineering and Food Engineering, Center of Technology, Florianopolis, SC 88040-901, Brazil. Electronic address:

The present work aimed to evaluate and to model the influence of UV-C light treatments with different irradiances (6.5, 13, 21, and 36 W/m) on Aspergillus fischeri and Paecilomyces niveus ascospores inactivation in clarified apple juice. Approximately 5. Read More

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November 2020

Cryopreservation of three Saprolegnia species (Oomycota): Preliminary evidence for the long-term archiving of water mould species.

Fungal Biol 2020 07 11;124(7):682-687. Epub 2020 May 11.

Institute for Veterinary Medical Research, Centre for Agricultural Research, 21Hungária krt, Budapest, H-1143, Hungary.

Saprolegnia spp. water moulds are opportunistic pathogens that can cause economic losses to aquaculture. The diseases caused by them are difficult to control since use of the effective drug, malachite green oxalate, is no longer permitted in several regions (including the European Union and USA). Read More

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Assessment of preservative potential of Bunium persicum (Boiss) essential oil against fungal and aflatoxin contamination of stored masticatories and improvement in efficacy through encapsulation into chitosan nanomatrix.

Environ Sci Pollut Res Int 2020 Aug 11;27(22):27635-27650. Epub 2020 May 11.

Laboratory of Herbal Pesticides, Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi, U.P., 221005, India.

The study reports the preservative efficacy of Bunium persicum (Boiss) essential oil (BPEO) against fungal and aflatoxin B (AFB) contamination of stored masticatories and boosting of its efficacy through encapsulation into chitosan. BPEO was chemically characterized through GC-MS analysis, which revealed γ-terpinene as the major compound. The BPEO at 1. Read More

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The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum.

J Appl Microbiol 2020 Aug 16;129(2):278-286. Epub 2020 Mar 16.

Department of Food Science, Faculty of Science, University of Copenhagen, Frederiksberg C, Denmark.

Aims: The aim of the study was to investigate the antifungal effects of a quorum sensing-molecule, 2-phenylethanol, against the food spoilage moulds Penicillium expansum and Penicillium nordicum.

Methods And Results: Conidial germination of the tested Penicillium spp. (three strains in total) were inhibited by treatments with 2-phenylethanol in a concentration-dependent manner. Read More

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Rapid PCR Method for the Selection of 1,3-Pentadiene Non-Producing Yeast Strains.

Foods 2020 Feb 7;9(2). Epub 2020 Feb 7.

Department of Genetics, Physiology and Microbiology. Biological Sciences Faculty. Complutense University of Madrid. José Antonio Nováis, 12. 28040 Madrid, Spain.

To prevent microbial growth and its consequences, preservatives such as sorbic acid or its salts, commonly known as sorbates, are added to foods. However, some moulds and yeasts are capable of decarboxylating sorbates and producing 1,3-pentadiene. This is a volatile compound with an unpleasant "petroleum-like "odour, which causes consumer rejection of the contaminated products. Read More

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February 2020

Application of (super)cavitation for the recycling of process waters in paper producing industry.

Ultrason Sonochem 2020 Jun 4;64:105002. Epub 2020 Feb 4.

Faculty of Mechanical Engineering, University of Ljubljana, Slovenia.

In paper production industry, microbial contaminations of process waters are common and can cause damage to paper products and equipment as well as the occurrence of pathogens in the end products. Chlorine omission has led to the usage of costly reagents and products of lower mechanical quality. In this study, we have tested a rotation generator equipped with two sets of rotor and stator assemblies to generate developed cavitation (unsteady cloud shedding with pressure pulsations) or supercavitation (a steady cavity in chocked cavitation conditions) for the destruction of a persistent bacteria Bacillus subtilis. Read More

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Identification of repositionable drugs with novel antimycotic activity by screening the Prestwick Chemical Library against emerging invasive moulds.

J Glob Antimicrob Resist 2020 06 28;21:314-317. Epub 2020 Jan 28.

Aix-Marseille Université, IRD, APHM, MEPHI, Marseille, France; IHU-Méditerranée Infection, Marseille, France. Electronic address:

Objectives: The incidence of severe filamentous fungal infections has increased over the past decade. Some of these filamentous fungi are resistant to available antifungals; it is thus urgent to find new compounds that are active against such life-threatening pathogens.

Methods: In this study, 1280 drugs (Prestwick Chemical Library) were tested against six multidrug-resistant (MDR) filamentous fungi, includingAspergillus, Fusarium, Scedosporium/Lomentospora, Rhizopus and Lichtheimia species. Read More

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New protocol for successful isolation and amplification of DNA from exiguous fractions of specimens: a tool to overcome the basic obstacle in molecular analyses of myxomycetes.

PeerJ 2020 24;8:e8406. Epub 2020 Jan 24.

W. Szafer Institute of Botany, Polish Academy of Sciences, Kraków, Poland.

Herbarium collections provide an essential basis for a wide array of biological research and, with development of DNA-based methods, they have become an invaluable material for genetic analyses. Yet, the use of such material is hindered by technical limitations related to DNA degradation and to quantity of biological material. The latter is inherent for some biological groups, as best exemplified by myxomycetes which form minute sporophores. Read More

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January 2020

Coconut Bio-yoghurt Phytochemical-chemical and Antimicrobial-microbial Activities.

Pak J Biol Sci 2019 Jan;22(11):527-536

Background And Objective: Coconut flour is known to be highly nutritious flour and contains high dietary fiber. The aim of this study was to make "bio-yoghurt beverage grafted with coconut flour and containing probiotic bacteria which is recommended as a functional milk product.

Materials And Methods: Chemical, phytochemical studies and antimicrobial activity have been performed on coconut flour which was used to make the beverage. Read More

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January 2019