1,376,855 results match your criteria mortality rates


Long-Term Outcomes in Patients with Post-Bulbar Ulcer Bleeding Compared to Bulbar Ulcer Bleeding in the Duodenum.

Digestion 2021 Sep 22:1-7. Epub 2021 Sep 22.

Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.

Background: Duodenal ulcers are classified into bulbar and post-bulbar ulcers. The aim of this study is to compare the long-term outcomes of patients with post-bulbar ulcer bleeding and those with bulbar ulcer bleeding.

Methods: A total of 272 patients with hemorrhagic duodenal ulcers requiring hospitalization were included. Read More

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September 2021

Comparison of the clinical characteristics and mortalities of severe COVID-19 patients between pre- and post-menopause women and age-matched men.

Aging (Albany NY) 2021 Sep 22;13(undefined). Epub 2021 Sep 22.

Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.

The mortality rate of young female COVID-19 patients is reported to be lower than that of young males but no significant difference in mortality was found between female and male COVID-19 patients aged over 65 years, and the underlying mechanism is unknown. We retrospectively analyzed clinical characteristics and outcomes of severely ill pre- and post-menopausal COVID-19 patients and compared with age-matched males. Of the 459 patients included, 141 aged ≤55, among whom 19 died (16 males vs. Read More

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September 2021

Classical Risk Factors for Ischemic Stroke are not Associated with Inpatient Post-Stroke Mortality in Sickle Cell Disease.

J Stroke Cerebrovasc Dis 2021 Sep 19;30(12):106089. Epub 2021 Sep 19.

Leo M. Davidoff Department of Neurosurgery, Montefiore Medical Center, Albert Einstein College of Medicine, 3316 Rochambeau Ave., Bronx, NY 10467, USA.

Objectives: Sickle cell disease is a common haemoglobinopathy that significantly increases the risk of ischemic stroke. Because the risk factors for ischemic stroke onset and mortality in non-sickle cell disease patients have been largely elucidated, this paper aims to analyze risk factors for ischemic stroke mortality in sickle cell disease patients, which remain largely unknown.

Materials/methods: The National Inpatient Sample database (2016-2017) was used to develop a multivariable regression model for risk quantification of known ischemic stroke risk factors for in-hospital mortality in ischemic stroke patients with and without sickle cell disease. Read More

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September 2021

Impact of Systemic Atherosclerosis on Clinical Characteristics and Short-term Outcomes in Patients with Deep Venous Thrombosis or Thrombophlebitis.

Am J Med Sci 2021 Sep 19. Epub 2021 Sep 19.

Department of Cardiology, Cardiology I, University Medical Center Mainz (Johannes Gutenberg-University Mainz), Mainz, Germany.

Background: Venous thromboembolism (VTE) and atherosclerosis are accompanied by substantial cardiovascular mortality; links between both disease entities were reported. We aimed to investigate the impact of systemic atherosclerosis on adverse outcomes in patients with deep venous thrombosis or thrombophlebitis (DVT) and to identify differences in DVT patients with and without systemic atherosclerosis.

Methods: The German nationwide inpatient sample was used for this analysis. Read More

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September 2021

Hypomethylating agents and FLT3 inhibitors as maintenance treatment for acute myeloid leukemia and myelodysplastic syndrome following allogeneic hematopoietic stem cell transplant - a systematic review and meta-analysis.

Transplant Cell Ther 2021 Sep 19. Epub 2021 Sep 19.

Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medical Oncology, Adult Leukemia Program, Dana-Farber Cancer Institute, Boston, MA.

Background: Disease relapse remains the major cause of death among patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) who receive an allogeneic hematopoietic cell transplant (allo-HCT). Maintenance treatment with FLT3 inhibitors and hypomethylating agents (HMA) has been studied in various clinical trials with mixed results.

Objective: To synthesize the current evidence on the efficacy and safety of FLT3 inhibitors and HMA for maintenance therapy following allo-HCT in AML and MDS. Read More

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September 2021

Inappropriate use of antibiotics exacerbates inflammation through OMV-induced pyroptosis in MDR Klebsiella pneumoniae infection.

Cell Rep 2021 Sep;36(12):109750

Laboratory of Molecular Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming, Yunnan 650106, China. Electronic address:

The inappropriate use of antibiotics is a severe public health problem worldwide, contributing to the emergence of multidrug-resistant (MDR) bacteria. To explore the possible impacts of the inappropriate use of antibiotics on the immune system, we use Klebsiella pneumoniae (K. pneumoniae) infection as an example and show that imipenem increases the mortality of mice infected by MDR K. Read More

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September 2021

New fractionations in breast cancer: a dosimetric study of 3D-CRT versus VMAT.

J Med Radiat Sci 2021 Sep 22. Epub 2021 Sep 22.

Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.

Introduction: Adjuvant radiation therapy (RT) following primary surgery in women affected by early breast cancer (EBC) plays a central role in reducing local recurrences and overall mortality. The FAST-FORWARD trial recently demonstrated that 1-week hypofractionated adjuvant RT is not inferior to the standard schedule in terms of local relapse, cosmetic outcomes and toxicity. The aim of this in silico study was to evaluate the dosimetric aspects of a 1-week RT course, administered through volumetric modulated arc therapy (VMAT), compared with traditional three-dimensional conformal radiation therapy (3D-CRT) with tangential fields. Read More

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September 2021

Prevalence, determinants, and outcomes of SARS-COV-2 infection among cancer patients. A population-based study in northern Italy.

Cancer Med 2021 Sep 22. Epub 2021 Sep 22.

Friuli Venezia Giulia Regional Health Coordination Agency, Udine, Italy.

Background: It is well established that cancer patients infected with SARS-CoV-2 are at particularly elevated risk of adverse outcomes, but the comparison of SARS-CoV-2 infection risk between cancer patients and cancer-free individuals has been poorly investigated on a population-basis.

Methods: A population-based study was thus conducted in Friuli Venezia Giulia region, northeastern Italy, to estimate prevalence and determinants of SARS-CoV-2 infection among cancer patients, as compared to cancer-free individuals, and to evaluate adverse outcomes of SARS-CoV-2 infection. The study included 263,042 individuals tested for SARS-CoV-2 in February-December 2020 with cancer history retrieved through the regional cancer registry. Read More

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September 2021

Right ventricular dysfunction and tricuspid regurgitation in functional mitral regurgitation.

ESC Heart Fail 2021 Sep 22. Epub 2021 Sep 22.

The Christ Hospital Health Network, 2139 Auburn Ave, Cincinnati, OH, 45219, USA.

Aim: The objective of this study was to investigate the prognostic importance of right ventricular dysfunction (RVD) and tricuspid regurgitation (TR) in patients with moderate-severe functional mitral regurgitation (FMR) receiving MitraClip procedure. RVD and TR grade are associated with cardiovascular mortality in the general population and other cardiovascular diseases. However, there are limited data from observational studies on the prognostic significance of RVD and TR in FMR receiving MitraClip procedure. Read More

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September 2021

Thromboelastography for monitoring resuscitation during acute hemorrhage.

Acad Emerg Med 2021 Sep 22. Epub 2021 Sep 22.

Department of Emergency Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.

Severe bleeding and coagulopathy contribute to high morbidity and mortality in patients undergoing surgery. While conventional coagulation testing is commonly used to guide transfusion, these assays do not reveal the complexities of hemostatic derangements and were not designed to predict bleeding or guide coagulation management. Point of care thromboelastography (TEG) and rotational thromboelastometry (ROTEM) assays measure fibrinolysis and were developed partly for the purpose of guiding hemostatic resuscitation. Read More

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September 2021

Management of acute upper GI bleeding: urgent vs. early endoscopy.

Dig Endosc 2021 Sep 22. Epub 2021 Sep 22.

Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Department of Surgery, 4/F Lue Che Wo Clinical Sciecens Building, Prince of Wales Hospital, Shatin, Hong Kong.

For decades, timing of endoscopy has been a controversy in the management of patients who present with upper gastrointestinal bleeding. The advent of endoscopic hemostatic therapy led to reduced further bleeding, surgery and mortality. Observational studies suggest that in patients at low risk of further bleeding, early endoscopy establishes diagnosis and allows their prompt hospital discharge. Read More

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September 2021

Impact of era of diagnosis on cause-specific late mortality among 77 423 five-year European survivors of childhood and adolescent cancer: the PanCareSurFup consortium.

Int J Cancer 2021 Sep 22. Epub 2021 Sep 22.

German Childhood Cancer Registry (GCCR), Division of Childhood Cancer Epidemiology, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), Johannes Gutenberg University Mainz, Germany.

Late mortality of European five-year survivors of childhood or adolescent cancer has dropped over the last 60 years, but excess mortality persists. There is little information concerning secular trends in cause-specific mortality among older European survivors. PanCareSurFup pooled data from 12 cancer registries and clinics in 11 European countries from 77 423 five-year survivors of cancer diagnosed before age 21 between 1940 to 2008 followed for an average age of 21 years and a total of 1. Read More

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September 2021

International Council of Nurses representing nursing at the World Health Organization: COVID-19, policy and holding politicians to account.

Authors:
Howard Catton

Int Nurs Rev 2021 Sep;68(3):267-269

International Council of Nurses, Geneva, Switzerland.

The International Council of Nurses is in a unique position to represent nurses at the World Health Organization, and its task has never been more urgent than this year. Amid the global COVID-19 pandemic, the death rates of nurses and other health care workers are truly shocking, with around 115 000 deaths. However, many countries do not collect statistics on health and care workers' deaths and infections from COVID-19, so the full extent of this awful situation is not known. Read More

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September 2021

Examining socio-economic factors to understand the hospital case fatality rates of COVID-19 in the city of São Paulo, Brazil.

Trans R Soc Trop Med Hyg 2021 Sep 22. Epub 2021 Sep 22.

Departamento de Geografia, Faculdade de Filosofia, Letras e Ciências Humanas e Instituto de Estudos Avançados da Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Understanding differences in hospital case fatality rates (HCFRs) of coronavirus disease 2019 (COVID-19) may help evaluate its severity and the capacity of the healthcare system to reduce mortality.

Methods: We examined the variability in HCFRs of COVID-19 in relation to spatial inequalities in socio-economic factors, hospital health sector and patient medical condition across the city of São Paulo, Brazil. We obtained the standardized hospital case fatality ratio adjusted indirectly by age and sex, which is the ratio between the HCFR of a specific spatial unit and the HCFR for the entire study area. Read More

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September 2021

Susceptibility of Boll Weevil (Coleoptera: Curculionidae) to Ethiprole, Differential Toxicity Against Selected Natural Enemies, and Diagnostic Concentrations for Resistance Monitoring.

J Econ Entomol 2021 Sep 22. Epub 2021 Sep 22.

Instituto Goiano de Agricultura, Rodovia 174 km 45, Zona Rural, Caixa postal 61, CEP 75915-000, Montividiu, GO, Brazil.

Synthetic insecticide application is one tactic for reducing boll weevil, Anthonomus grandis grandis Boheman (Coleoptera: Curculionidae), infestations during the cotton, Gossypium hirsutum L., reproductive stage. We assessed the susceptibility of the boll weevil and its natural enemies to ethiprole (mode of action 2B), a phenylpyrazole insecticide, and diagnostic concentrations of ethiprole indicative of boll weevil susceptibility. Read More

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September 2021

Trends in peripheral arterial disease incidence and mortality in EU15+ countries 1990-2017.

Eur J Prev Cardiol 2021 Sep;28(11):1201-1213

Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, UK.

Aims: The aim was to assess trends in peripheral arterial disease (PAD) incidence and mortality rates in European Union(15+) countries between 1990 and 2017.

Methods And Results: This observational study used data obtained from the 2017 Global Burden of Disease study. Age-standardised mortality and incidence rates from PAD were extracted from the Global Health Data Exchange for EU15+ countries for the years 1990-2017. Read More

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September 2021

Cardiorespiratory fitness and survival following cancer diagnosis.

Eur J Prev Cardiol 2021 Sep;28(11):1242-1249

Sackler School of Medicine, Tel-Aviv University, Israel.

Aims: Data on the association of cardiorespiratory fitness with survival of cancer patients are limited. This study aimed to evaluate the association between midlife cardiorespiratory fitness and survival after a subsequent cancer diagnosis.

Methods: We evaluated 19,134 asymptomatic self-referred adults who were screened in preventive healthcare settings. Read More

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September 2021

Early cardiovascular structural and functional abnormalities as a guide to future morbid events.

Eur J Prev Cardiol 2021 Sep;28(11):1214-1221

Department of Medicine, Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN, USA.

Aims: Our aim was to evaluate the predictive value of a battery of 10 non-invasive tests of cardiovascular structural and functional health on the future risk of cardiovascular morbid events.

Methods And Results: A total of 1900 asymptomatic adults concerned about their risk for cardiovascular disease underwent non-invasive assessment with 10 tests of vascular and cardiac structure and function. A disease score (DS) was calculated for each individual based on these 10 tests. Read More

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September 2021

The morbidity and mortality of COVID-19 are associated with ABO and Rh blood groups.

Eur J Prev Cardiol 2021 Sep;28(11):e26-e28

Department of Biology, College of Sciences, Shiraz University, Iran.

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September 2021

Non-adherence to established dietary guidelines associated with increased mortality: the Copenhagen General Population Study.

Eur J Prev Cardiol 2021 Sep;28(11):1259-1268

Department of Internal Medicine, Zealand University Hospital, Denmark.

Aims: The relevance of adherence to established dietary guidelines is repeatedly challenged. We hypothesised that non-adherence to established dietary guidelines is associated with an excess risk of cardiovascular, non-cardiovascular and all-cause mortality.

Methods: We studied 100,191 white adult Danes aged 20-100 years recruited in 2003-2015 and followed up until December 2018. Read More

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September 2021

Bereavement in the year before a first myocardial infarction: Impact on prognosis.

Eur J Prev Cardiol 2021 Sep;28(11):1229-1234

Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Background: Death of the spouse in middle and old age is associated with an increased risk of cardiovascular and total mortality, particularly during the months after the loss. Knowledge regarding the effect of bereavement on prognosis in acute myocardial infarction (AMI) is limited. We analysed whether bereavement the year before the AMI is associated with prognosis. Read More

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September 2021

Physical exercise training in patients with a Fontan circulation: A systematic review.

Eur J Prev Cardiol 2021 Sep;28(11):1269-1278

Department of Pediatric Cardiology, Erasmus MC-Sophia Children's Hospital, The Netherlands.

Background: Patients with a Fontan circulation have a reduced exercise capacity, which is an important prognostic predictor of morbidity and mortality. A way to increase exercise capacity in Fontan patients might be exercise training. This systematic review assesses the effects of exercise training investigated in Fontan patients in order to provide an overview of current insights. Read More

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September 2021

Daratumumab for immune thrombotic thrombocytopenic purpura.

Blood Adv 2021 Sep 22. Epub 2021 Sep 22.

University Hospital Zürich, Zürich, Switzerland.

Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy. It is caused by a severe ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motifs, 13) deficiency due to circulating autoantibodies, and is associated with significant morbidity and mortality. Current treatment options include plasma exchange, immunosuppression, and caplacizumab. Read More

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September 2021

Anticoagulation Therapy for Portal Vein Thrombosis in Patients with Cirrhosis in a Tertiary Center Experience.

J Gastrointestin Liver Dis 2021 Sep 21;30(3):374-379. Epub 2021 Sep 21.

Carol Davila University of Medicine and Pharmacy, Faculty of Medicine, Bucharest; Centre for Digestive Diseases and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania.

Background And Aims: The evidence regarding the use of anticoagulant (AC) agents in portal vein thrombosis (PVT) is increasing and, most patients undergo chronic treatment with low molecular weight heparin (LMWH) or vitamin K antagonists (VKA). Nevertheless, there are no clear data about who should receive antithrombotic therapy, when to initiate it, how long and what dose should be used for this set of patients. The aim of the study was to assess the outcome of patients with cirrhosis and portal vein thrombosis who received AC therapy, in terms of thrombus regression, bleeding events and survival rates. Read More

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September 2021

Creating safe spaces to prevent unintentional childhood injuries among the Bedouins in southern Israel: A hybrid model comprising positive deviance, community-based participatory research, and entertainment-education.

PLoS One 2021 22;16(9):e0257696. Epub 2021 Sep 22.

Department of Communication, The University of Texas at El Paso, El Paso, Texas, United States of America.

Background: Despite several intervention programs, the Bedouin population living in the Southern District of Israel has the highest mortality rate among children and adolescents from unintentional injuries. Our research questions asked: (1) How does increasing the involvement and participation of Bedouin community members influence the issue of unintentional injuries among children? (2) How does reframing of the technical issue of safety into security influence community involvement and cooperation?

Objectives: 1) To identify effective and efficacious positive deviance practices through community-based participatory research with adults, children, and professionals in the Bedouin community. 2) To create wider and deeper connections and cohesion between and among diverse Bedouin communities by seeding and sparking opportunities for social networking and cross-learning. Read More

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September 2021

Burden of Hypertensive Heart Disease in Iran during 1990-2017: Findings from the Global Burden of Disease study 2017.

PLoS One 2021 22;16(9):e0257617. Epub 2021 Sep 22.

Hospital Management Research Center, Iran University of Medical Sciences, Tehran, Iran.

Background: Hypertension and its consequent end-organ damage including Hypertensive Heart Disease (HHD) are a major concern that impact health, resulting into impairment and reduced quality of life (QOL). The purpose of this study was to describe the burden of HHD in Iran and comparing it with the World Bank upper middle-income countries (UMICs) in terms of disability-adjusted life years (DALY), mortality and prevalence.

Methods: Using data from the Global Burden of Disease study 2017, we compared the number of DALYs, deaths and prevalence trends for HHD from 1990 to 2017 in all age groups for both sex in Iran, and compared the epidemiology and trends with UMICs and globally. Read More

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September 2021

Breast cancer patient experiences through a journey map: A qualitative study.

PLoS One 2021 22;16(9):e0257680. Epub 2021 Sep 22.

Clinical Psychology and Psychobiology Department, Faculty of Psychology, University of Barcelona, Barcelona, Spain.

Background: Breast cancer is one of the most prevalent diseases in women. Prevention and treatments have lowered mortality; nevertheless, the impact of the diagnosis and treatment continue to impact all aspects of patients' lives (physical, emotional, cognitive, social, and spiritual).

Objective: This study seeks to explore the experiences of the different stages women with breast cancer go through by means of a patient journey. Read More

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September 2021

Socio-economic and demographic determinants of fertility in six selected Pacific Island Countries: An empirical study.

PLoS One 2021 22;16(9):e0257570. Epub 2021 Sep 22.

Discipline of Economics, School of Accounting, Finance and Economics, The University of the South Pacific, Suva, Fiji.

In this study, we seek to perform macro analysis of fertility in a panel of 6 selected Pacific Island Countries (PICs, hereafter). The macro analysis with secondary data, mostly obtained from World Bank database, stretched over the period 1990-2019 was stacked randomly in a balanced panel set-up, within which the most preferred fixed effect model is used for multivariate analysis. Pooled OLS and Random effect estimation techniques were applied for comparing results. Read More

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September 2021