42,033 results match your criteria mortality indicators

A novel nomogram with preferable capability in predicting the overall survival of patients after radical esophageal cancer resection based on accessible clinical indicators: A comparison with AJCC staging.

Cancer Med 2021 Jun 15. Epub 2021 Jun 15.

Department of Thoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Background: Esophageal cancer (EC) is a malignant tumor with high mortality. Nomogram is an important tool used in clinical prognostic assessment. We aimed to establish a novel nomogram to predict the overall survival (OS) of EC patients after radical esophagectomy. Read More

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Risk areas for Human Visceral Leishmaniosis 2007-2018: A temporal and spatial analysis in Ceará, Brazil.

Zoonoses Public Health 2021 Jun 14. Epub 2021 Jun 14.

Faculty of Medicine, Postgraduate Program in Public Health, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Visceral leishmaniasis (VL) is considered as an important tropical disease because it rapidly spreads across a wide geographical area. This study aimed to analyse the temporal and spatial patterns of incidence, mortality and case fatality rates due to human VL in Ceará, Brazil, from 2007 to 2018. This is an ecological study involving time series and spatial analyses, and data were obtained from human VL notifications. Read More

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Association of Preadmission Statin Use and Mortality in Critically Ill Patients: A Meta-Analysis of Cohort Studies.

Front Med (Lausanne) 2021 28;8:656694. Epub 2021 May 28.

Department of Burn Surgery, Changhai Hospital, The Naval University, Shanghai, China.

A large number of studies have been conducted to determine whether there is an association between preadmission statin use and improvement in outcomes following critical illness, but the conclusions are quite inconsistent. Therefore, this meta-analysis aims to include the present relevant PSM researches to examine the association of preadmission use of statins with the mortality of critically ill patients. The PubMed, Web of Science, Embase electronic databases, and printed resources were searched for English articles published before March 6, 2020 on the association between preadmission statin use and mortality in critically ill patients. Read More

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Availability, utilization and quality of emergency obstetric care services in Sousse, Tunisia.

Pan Afr Med J 2021 16;38:272. Epub 2021 Mar 16.

University of Sousse, Faculty of Medicine of Sousse, Department of Family and Community Medicine, Research Laboratory "LR12ES03", 4000, Sousse, Tunisia.

Introduction: emergency obstetric care (EmOC) is a high-impact priority intervention strongly recommended for improving maternal health outcomes. The objectives of this study were to assess the availability, utilization, and quality of emergency obstetric care services in the Governorate of Sousse (Tunisia).

Methods: a cross-sectional study was conducted among public health facilities which performed deliveries in Sousse in 2017. Read More

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Synchronous thyroid cancer on the edge: Incidentalomas of 18F-FDG PET/CT in clinical practice.

Niger J Clin Pract 2021 Jun;24(6):937-942

Department of Nuclear Medicine, Gulhane Training and Research Hospital, Ankara, Turkey.

Aims: The objective of this study was to discuss the outcomes of the oncology patients whose PET/CT scans show incidental focal thyroid 18F-FDG uptake.

Methods: This retrospective analysis examined 2575 18F-FDG PET/CT scans from 1803 patients with no known thyroid cancer history. The survival rates were analyzed for patients with and without cytopathological evaluation. Read More

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Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken.

Animal 2021 Jun 10;15(7):100261. Epub 2021 Jun 10.

The Royal Veterinary College, Hawkshead Lane, Brookmans Park, Hatfield AL9 7TA, United Kingdom.

Broiler chickens are prone to a range of complex health and welfare issues. To support informed selection of welfare traits whilst minimising impact on production efficiency and to address a major gap in understanding, we systematically explored associations between health and behavioural indicators of broiler welfare. One conventional (CNV, n = 350) and two slow-growing broiler breeds (SGH and SGN, respectively n = 400) were reared from hatch in pens of 50 birds. Read More

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New Insight To The Rol Of Α-Enolase (Eno-1) As Immunological Marker In Rainbow Trout Fry.

Dev Comp Immunol 2021 Jun 9:104163. Epub 2021 Jun 9.

Grupo de Marcadores Inmunológicos, Laboratorio de Genética e Inmunología Molecular, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Avenida Universidad #330, 2373223, Valparaíso, Chile; Núcleo Biotecnológico de Curauma (NBC), Pontificia Universidad Católica de Valparaíso, Avenida Universidad #330, 2373223, Valparaíso, Chile. Electronic address:

α-Enolase is an enzyme of the glycolytic pathway that has also been involved in vertebrate inflammatory processes through its interaction with plasminogen. However, its participation in the immune response of lower vertebrates during early life development is unknown. Opportunistic pathogens in salmon farming are the principal cause of mortality in the fry stage. Read More

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Identifying counties at risk of high overdose mortality burden during the emerging fentanyl epidemic in the USA: a predictive statistical modelling study.

Lancet Public Health 2021 Jun 9. Epub 2021 Jun 9.

Department of Medicine, University of California, San Diego, CA, USA.

Background: The emergence of fentanyl around 2013 represented a new, deadly stage of the opioid epidemic in the USA. We aimed to develop a statistical regression approach to identify counties at the highest risk of high overdose mortality in the subsequent years by predicting annual county-level overdose death rates across the contiguous USA and to validate our approach against observed overdose mortality data collected between 2013 and 2018.

Methods: We fit mixed-effects negative binomial regression models to predict overdose death rates in the subsequent year for 2013-18 for all contiguous state counties in the USA (ie, excluding Alaska and Hawaii). Read More

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Hyperferritinemia: A Diagnostic Marker for Disseminated Neonatal Herpes Simplex Virus Infection?

Pediatr Ann 2021 Jun 1;50(6):e264-e267. Epub 2021 Jun 1.

Although the prognosis of neonatal herpes simplex virus (HSV) infection has improved with intravenous acyclovir, the morbidity and mortality of disseminated disease remains high. Transaminitis and thrombocytopenia have been reported to be sensitive markers of neonatal HSV disease; however, early diagnosis remains a challenge due to a lack of specific clinical and laboratory indicators for this disease process. Ferritin, an acute phase reactant known for its use in diagnosing hemophagocytic lymphohistiocytosis, has recently been reported as extremely elevated in neonates with disseminated HSV due to its high inflammatory nature. Read More

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[Influencing factors of weaning outcome of intensive care unit patients with planned extubation].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 May;33(5):563-567

Department of Intensive Care Unit, First Hospital of Qinhuangdao, Qinhuangdao 066000, Hebei, China. Corresponding author: Chen Xiaomin, Email:

Objective: To determine the risk factors of extubation failure and its effect on the prognosis of patients who had successfully passed a spontaneous breathing trial (SBT).

Methods: The clinical data of patients with mechanical ventilation more than 24 hours who passed SBT admitted to department of intensive care unit (ICU) of First Hospital of Qinhuangdao from November 2018 to November 2019 were retrospectively analyzed. According to the outcome of weaning within 48 hours after weaning, patients were divided into weaning success group and weaning failure group. Read More

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Fostering cardiovascular health at work - case study from Senegal.

BMC Public Health 2021 Jun 10;21(1):1108. Epub 2021 Jun 10.

Novartis Foundation, Basel, Switzerland.

Background: Of the 15 million annual premature deaths from non-communicable diseases (NCDs), 85% occur in low- and middle-income countries (LMICs). Affecting individuals in the prime of their lives, NCDs impose severe economic damage to economies and businesses, owing to the high mortality and morbidity within the workforce. The Novartis Foundation urban health initiative, Better Hearts Better Cities, was designed to improve cardiovascular health in Dakar, Senegal through a combination of interventions including a workplace health program. Read More

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Grandparenting, Social Relations, and Mortality in Old Age.

Res Aging 2021 Jun 10:1640275211015433. Epub 2021 Jun 10.

Graduate School of Public Health, 6614University of Pittsburgh, PA, USA.

Guided by a convoy model of social relations, this study investigates the relationships between grandparenting status, social relations, and mortality among community-dwelling grandparents age 65 and older who are caring for their grandchildren. The data were drawn from the 2008 and 2016 waves of the Health and Retirement Study ( = 564). Latent class analysis was used to identify the social network structure based on six indicators of interpersonal relationships and activities. Read More

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A qualitative study on the multi-level process of resilience development for adults recovering from eating disorders.

J Eat Disord 2021 Jun 9;9(1):66. Epub 2021 Jun 9.

School of Psychology, University College Dublin, Dublin, Ireland.

Background: Resilience research to date has been criticised for its consideration of resilience as a personal trait instead of a process, and for identifying individual factors related to resilience with no consideration of the ecological context. The overall aim of the current study was to explore the multi-level process through which adults recovering from EDs develop resilience, from the perspectives of clients and clinicians. The objective of this research was to outline the stages involved in the process of developing resilience, which might help to inform families and services in how best to support adults with EDs during their recovery. Read More

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A systematic review and meta-analysis of effect evaluation of traditional Chinese medicine in treating acute respiratory distress syndrome.

Ann Palliat Med 2021 May;10(5):5520-5532

Department of Respiratory Medicine, Yichang Hospital of Traditional Chinese Medicine, Yichang, China; College of Traditional Chinese Medicine, China Three Gorges University, Yichang, China; College of Medical Science, China Three Gorges University, Yichang, China.

Background: It was to systematically evaluate the effects of traditional Chinese medicine (TCM) in the treatment of acute respiratory distress syndrome (ARDS), and provide a theoretical basis for the clinical treatment of ARDS.

Methods: English databases of PubMed, Embase, Medline, Spring, Cochrane Library, and Web of Science were searched, and the randomized controlled trial literatures on the treatment of ARDS patients with TCM published from January 1, 2001 to December 31, 2020 were screened. Then, Cochrane Handbook 5. Read More

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Clinical implications and indicators of mortality among patients hospitalized with concurrent COVID-19 and myocardial infarction.

Turk Kardiyol Dern Ars 2021 06;49(4):293-302

Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Objective: Acute ischemic cardiac events can complicate coronavirus disease 2019 (COVID-19). We report the in-hospital characteristics of patients with acute myocardial infarction and concomitant COVID-19.

Methods: This was a registry-based retrospective analysis of patients admitted with positive COVID-19 tests who suffered acute myocardial infarction either before or during hospitalization; from 1 March 2020 to 1 April 2020 in a tertiary cardiovascular center-Tehran Heart Center. Read More

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[Neonatal near miss in referral hospitals for high-risk pregnancy and childbirth: a cross-sectional study].

Cad Saude Publica 2021 4;37(6):e00196220. Epub 2021 Jun 4.

Universidade Federal de Pernambuco, Recife, Brasil.

The article aimed to describe and compare indicators of neonatal near miss in referral hospitals for high-risk pregnancy and childbirth. This exploratory study was performed in two general hospitals in Recife, Pernambuco, Brazil. The study included cases of neonatal near miss in the year 2016 with gestational age < 33 weeks, birthweight < 1,750g, 5-minute Apgar < 7, or admission to the neonatal intensive care unit (ICU) and that remained alive at 7 days of life. Read More

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Examining developmental plasticity in the skeletal system through a sensitive developmental windows framework.

Cait B McPherson

Am J Phys Anthropol 2021 Jun 8. Epub 2021 Jun 8.

School of Anthropology, University of Arizona, Tucson, Arizona, USA.

Developmental plasticity facilitates energetically costly but potentially fitness-enhancing adjustments to phenotypic trajectories in response to environmental stressors, and thus may significantly impact patterns of growth, morbidity, and mortality over the life course. Ongoing research into epigenetics and developmental biology indicate that the timing of stress exposures is a key factor when assessing their impact on developmental processes. Specifically, stress experienced within sensitive developmental windows (SDWs), discrete developmental periods characterized by heightened energy requirements and rapid growth, may alter the pace and tempo of growth in ways that significantly influence phenotypic development over both the short and long term. Read More

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Georgian Med News 2021 Apr(313):146-152

1Karaganda Medical University, Department of Morphology and Physiology, Karaganda, Kazakhstan.

The rapid development of molecular biology and genetic engineering contributes to the creation of plants with desired properties in a short time. One of the aspects of the study of genetically modified organisms (GMO) and genetically modified products (GMP) is the study of their impact on humans, animals and the environment. Subject of research - changes in the morph functional indicators of the reproductive system of mice. Read More

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Effects of omega-3 fatty acids and metformin combination on diabetic cardiomyopathy in rats through autophagic pathway: Effects of omega-3 fatty acids and metformin combination on diabetic cardiomyopathy: Role of autophagy.

J Nutr Biochem 2021 Jun 5:108798. Epub 2021 Jun 5.

Clinical Pharmacology Department, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.

Diabetic cardiomyopathy (DCM) is a primary cause of increased morbidity and mortality in diabetics. Evidence has suggested a pivotal role for interrupted mitochondrial dynamics and quality control machinery in the onset and development of DCM. Sequestosome 1 (SQSTM1) is a major reporter of selective autophagic activity. Read More

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A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol.

Clin Exp Nephrol 2021 Jun 8. Epub 2021 Jun 8.

Hull York Medical School, Hull, UK.

Background: Incremental haemodialysis/haemodiafiltration (HD) may help reduce early mortality rates in patients starting HD. This mixed-method feasibility study aims to test the acceptability, tolerance and safety of a novel incremental HD regime, and to study its impact on parameters of patient wellbeing.

Method: We aim to enrol 20 patients who will commence HD twice-weekly with progressive increases in duration and frequency, achieving conventional treatment times over 15 weeks (incremental group). Read More

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The Rotavirus Surveillance System in Yemen: Evaluation Study.

JMIR Public Health Surveill 2021 Jun 8;7(6):e27625. Epub 2021 Jun 8.

Department of Community Medicine, Public Health and Family Medicine, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.

Background: Rotavirus (RV) kills over 185,000 children <5 years every year and is responsible for over one-third of all child diarrheal deaths worldwide. The Rotavirus Surveillance System (RVSS) in Yemen was launched in 2007 at five sentinel sites to monitor the impact of the vaccine on RV morbidity and mortality.

Objective: This study aimed to determine the usefulness of the RVSS, assess its performance, and identify the strengths and weaknesses of its implementation. Read More

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Why is it important to report early possible COVID-19 PET/CT findings in cancer patients? Explaining with a case series.

Indian J Cancer 2021 Apr-Jun;58(2):248-258

Department of Obstetrics and Gynecology, Tepecik Training and Research Hospital, Izmir, Turkey.

Background: Coronavirus disease-2019 (COVID-19) causing a pandemic mostly results in mild symptoms; however, it can evolve into serious complications. It is emphasized that if the term from the recent anticancer treatment to the diagnosis of COVID-19 was short, the probability of serious events increased in cancer patients. Therefore, early detection of COVID-19 and prevention of serious events is very important. Read More

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Temporal Patterns of High-Spend Subgroups Can Inform Service Strategy for Medicare Advantage Enrollees.

J Gen Intern Med 2021 Jun 7. Epub 2021 Jun 7.

OptumLabs at UnitedHealth Group, Minneapolis, MN, USA.

Background: Most healthcare costs are concentrated in a small proportion of individuals with complex social, medical, behavioral, and clinical needs that are poorly met by a fee-for-service healthcare system. Efforts to reduce cost in the top decile have shown limited effectiveness. Understanding patient subgroups within the top decile is a first step toward designing more effective and targeted interventions. Read More

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Prediction of mortality in severely injured patients with facial bone fractures.

Oral Maxillofac Surg 2021 Jun 8. Epub 2021 Jun 8.

Department of Dentistry, Institute of Postgraduate Education, O. Bogomolets National Medical University, 34, Peremohy Avenue, the 2nd floor of the "physical-chemical" building, Kyiv, Ukraine.

Purpose: Identify the most common concomitant injuries associated with facial trauma, and compare the efficacy of various scoring systems in estimation of mortality risks in this category of patients.

Methods: The study evaluated patients with facial and concomitant injuries, who received the multidisciplinary treatment in a specialized trauma hospital. Values of New Injury Severity Score, Glasgow Coma Scale, Facial Injury Severity Scale, age, and length of hospital stay were statistically analysed to determine presence of relationships between these indicators and define factors that significantly associated with lethal outcome. Read More

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A survey of dairy goat kid-rearing practices on Canadian farms and their associations with self-reported farm performance.

J Dairy Sci 2021 Jun 4. Epub 2021 Jun 4.

Department of Animal Science, McGill University, Sainte-Anne-de-Bellevue, Québec H9X 3V9, Canada. Electronic address:

Although future production of dairy goats is influenced by kid-rearing practices, little is known regarding which practices maximize kid growth, welfare, and future production success. The objectives of this survey study were to (1) identify common rearing practices of Canadian commercial dairy goat farms and evaluate their associations with 6 farm performance indicators and (2) determine if farms could be grouped by management style on the basis of the 6 performance indicators and compare rearing practices common across the different groups. A survey was sent by post or electronic media to reach dairy goat producers across Canada. Read More

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Prevalence and correlates of malnutrition among hemodialysis patients at hebron governmental hospital, Palestine: cross-sectional study.

BMC Nephrol 2021 Jun 7;22(1):214. Epub 2021 Jun 7.

Healthy and Therapeutic Nutrition Department, Faculty of Medicine and Health Sciences, Palestine Polytechnic University, Hebron, Palestine.

Background: Malnutrition is a usually observed condition among patients on hemodialysis and is considered one of sturdiest indicators of mortality and morbidity.

Objectives: The current study was performed to assess the prevalence of malnutrition, to verify whether functional status is associated with malnutrition, and to explore the probable factors related to malnutrition among a sample of hemodialysis patients at Hebron Governmental Hospital in West Bank, Palestine.

Methods: A cross-sectional study was conducted on hemodialysis patients in Hebron Governmental Hospital at Hebron city/Palestine. Read More

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Creatinine-lactate score predicts mortality in non-acetaminophen-induced acute liver failure in patients listed for liver transplantation.

BMC Gastroenterol 2021 Jun 7;21(1):252. Epub 2021 Jun 7.

Laboratorio de Investigaçao Medica 37, Departamento de Gastroenterologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo - HCFMUSP, Sao Paulo, SP, Brazil.

Background: The aim of this study was to analyze prognostic indicators of in-hospital mortality among patients listed for urgent liver transplantation (LT) for non-acetaminophen (APAP)-induced acute liver failure (ALF).

Methods: ALF patients listed for LT according to the King's College Criteria were retrospectively reviewed. Variables were recorded from medical records and electronic databases (HCMED and RedCap). Read More

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Biomarkers in delirium: A systematic review.

J Psychosom Res 2021 Jun 1;147:110530. Epub 2021 Jun 1.

Centre for Interventions in Infection, Inflammation and Immunity (4i) and School of Medicine, University of Limerick, Limerick, Ireland; Cognitive Impairment Research Group, School of Medicine, University of Limerick, Limerick, Ireland. Electronic address:

Background: Delirium is a common neuropsychiatric disorder associated with prolonged hospital stays, and increased morbidity and mortality. Diagnosis is frequently missed due to varying disease presentation and lack of standardized testing. We examined biomarkers as diagnostic or prognostic indicators of delirium, and provide a rational basis for future studies. Read More

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Comparison of Immediate and Sequential Withdrawal of a Systemic Glucocorticoid in the Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Parallel-Controlled, Open-Label Study.

Front Mol Biosci 2021 20;8:639079. Epub 2021 May 20.

Department of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) were treated with immediate or sequential withdrawal after 5 days of systemic glucocorticoids. The effects of the two withdrawal methods on the prognosis of patients were compared at 30, 90, 180, and 360 days after discharge. A multicenter, randomized, double-blind, parallel-controlled, open-label study was conducted in the respiratory department of tertiary hospitals in Central China. Read More

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Development of Quality Indicators for the Management of Acute Type A Aortic Dissection.

Can J Cardiol 2021 Jun 3. Epub 2021 Jun 3.

Division of Cardiac Surgery, Department of Surgery, Western University, London, ON.

In an effort to further improve surgical outcomes in patients with acute type A aortic dissection (ATAD), the Canadian Thoracic Aortic Collaborative (CTAC), with the support of the Canadian Society of Cardiac Surgeons (CSCS), endeavored to develop quality indicators (QIs) for the management of patients with ATAD. After two successive consultations with the CTAC membership, 11 QIs were selected and separated into 5 broad categories: pre-operative (time from presentation to diagnosis, time from presentation to the operating room), intra-operative (use of hypothermic circulatory arrest and antegrade cerebral perfusion), 30-day outcomes (30-day rates of all-cause mortality, 30-day rates of new post-operative stroke), 1-year outcomes (1-year rates of follow-up imaging, 1-year rates of all-cause mortality, and 1-year rates of surgical re-intervention), and institutional (institutional surgical volumes, individual surgical volumes and presence of institutional aortic disease teams). The purpose of this manuscript was to describe the process by which QIs for the management of ATAD were developed and the feasibility by which they may be collected using existing clinical and administrative data sources. Read More

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