39,783 results match your criteria mortality gastrointestinal


A REVIEW OF MORTALITY IN TENTACLED SNAKES () IN A MULTI-INSTITUTION ZOOLOGICAL COLLECTION BETWEEN 1966 AND 2017.

J Zoo Wildl Med 2021 Sep;52(3):909-917

Wildlife Conservation Society, Bronx Zoo Herpetology Department, Central Park Zoo, and Zoological Health Program, Bronx, NY 10460 USA.

The tentacled snake () is a viviparous aquatic snake that is a desirable species to exhibit in zoological collections because of its unique appearance and feeding strategies. Despite its presence in zoo collections over the past 50 yr, a comprehensive review of mortality and morbidity in the species has not been published. This study retrospectively reviewed 125 pathology reports from tentacled snakes in a multi-institution zoological collection in New York (The Wildlife Conservation Society's Bronx and Central Park zoos) between 1966 and 2017. Read More

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September 2021

REVIEW OF HISTOLOGIC LESIONS AND MORTALITY IN RIO CAUCA CAECILIANS () OVER A 22-YEAR PERIOD.

J Zoo Wildl Med 2021 Sep;52(3):901-908

Zoological Pathology Program, Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Brookfield, IL 60513, USA.

Rio Cauca caecilians () are a unique, fully aquatic species of amphibian from the order Gymnophiona. They are housed in several zoological institutions and aquaria with limited information available regarding health and disease. This retrospective study evaluates common pathologic findings and causes of mortality of Rio Cauca caecilians from three different institutions over a 22-y period. Read More

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September 2021

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal metastasis of non-primary origin.

Langenbecks Arch Surg 2021 Oct 23. Epub 2021 Oct 23.

Peritoneal Tumours Unit, IRCCS, Regina Elena National Cancer Institute, via Elio Chianesi 53, 00144, Rome, Italy.

Purpose: The objective of this study was to analyze the role of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy that has developed in the treatment of patients with peritoneal metastasis of non-primary origin.

Methods: Patients who underwent treatment for secondary gastrointestinal and ovarian malignancies over a 20-year period were reviewed. Survival curves were estimated by the Kaplan-Meier product limit method and the log-rank test was used to assess differences between subgroups. Read More

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October 2021

Stakeholder Perceptions of Disease Management for Dairy Calves: "It's Just Little Things That Make Such a Big Difference".

Animals (Basel) 2021 Sep 28;11(10). Epub 2021 Sep 28.

Department of Animal Health, Behaviour and Welfare, Harper Adams University, Newport TF10 8NB, Shropshire, UK.

Calf morbidity and mortality rates are often high in dairy herds, raising animal welfare concerns and negatively affecting farm economic efficiency and future performance. Disease prevention is critical to maintain calves in good health, but interventions are dependent upon the persons conducting them. This paper explores the perceptions of farmers, farm workers, veterinarians, and other advisors on the management of calfhood disease on dairy farms in England. Read More

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September 2021

Feeding intolerance score in critically ill patients with enteral nutrition: A post hoc analysis of a prospective study.

Nutr Clin Pract 2021 Oct 22. Epub 2021 Oct 22.

Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, PR China.

Background: Feeding intolerance (FI) is common in critically ill patients fed with enteral nutrition. Although there is increasing evidence showing the association between FI and mortality, no reliable quantitative assessment was available in clinical practice. In this study, we proposed a FI scoring system based on gastrointestinal (GI) symptoms to assist the implementation of enteral nutrition and assessed its association with 28-day mortality. Read More

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October 2021

Perioperative Outcome in Dogs Undergoing Emergency Abdominal Surgery: A Retrospective Study on 82 Cases (2018-2020).

Vet Sci 2021 Sep 28;8(10). Epub 2021 Sep 28.

Department of Veterinary Sciences, Veterinary Teaching Hospital "Mario Modenato", University of Pisa, 56122 Pisa, Italy.

Emergency abdominal surgery carries high morbidity and mortality rates in human medicine; however, there is less evidence characterising the outcome of these surgeries as a single group in dogs. The aim of the study was to characterise the clinical course, associated complications and outcome of dogs undergoing emergency abdominal surgery. A retrospective study was conducted. Read More

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September 2021

Previous Extrapulmonary Malignancies Impact Outcomes in Patients With Surgically Resected Lung Cancer.

Front Surg 2021 5;8:747249. Epub 2021 Oct 5.

Department of Surgical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.

As the overall survival of patients with cancer continues to improve, the incidence of second primary malignancies seems to be increasing. Previous studies have shown controversial results regarding the survival of patients with primary lung cancer with previous extrapulmonary malignancies. This study aimed to determine the clinical picture and outcomes of this particular subgroup of patients. Read More

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October 2021

Perioperative Use of Glucocorticoids and Intraoperative Hypotension May Affect the Incidence of Postoperative Infection in Patients with Gastric Cancer: A Retrospective Cohort Study.

Cancer Manag Res 2021 8;13:7723-7734. Epub 2021 Oct 8.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), The First Department of Gastrointestinal Surgery, Peking University Cancer Hospital & Institute, Beijing, People's Republic of China.

Background: In patients undergoing surgical resection for gastric cancer, postoperative complications-in particular, postoperative infections-remain an important problem and can result in delayed recovery and increased postoperative mortality.

Objective: To investigate the association between perioperative anesthesia management and postoperative infectious complications in patients undergoing resection for gastric cancer.

Design: Retrospective cohort study. Read More

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October 2021

The Incidence and Mortality Impact of Gastrointestinal Bleeding in Hospitalized COVID-19 Patients.

Clin Exp Gastroenterol 2021 8;14:405-411. Epub 2021 Oct 8.

Division of Gastroenterology, BronxCare Hospital Center, Clinical Affiliate of Mt Sinai Health Systems and Academic Affiliate of Icahn School of Medicine, Bronx, NY, 10457, USA.

Background: Patients requiring hospitalization to critical care units are at a higher risk for gastrointestinal (GI) bleeding. Although severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection is predominantly a pulmonary disease, other serious manifestations including thromboembolic phenomenon are reported. Acute respiratory distress syndrome (ARDS) requiring mechanical ventilation, use of steroids and anticoagulation are all known to increase the risk of GI bleeding significantly. Read More

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October 2021

Acute Pancreatitis and COVID-19: A Single-Center Experience.

J Multidiscip Healthc 2021 9;14:2857-2861. Epub 2021 Oct 9.

Department of Critic Area, I Unit COVID, Monaldi-Cotugno Hospital, Naples, Italy.

Gastrointestinal involvement in SARS-CoV-2 disease (COVID-19) can occur and evolve fatally. Reports are emerging that SARS-CoV-2 virus attacks the pancreatic cells, causing the boost of amylase and lipase serum activity and rarely frank pancreatitis. We retrospectively assessed all the patients admitted to the respiratory sub-intensive care and evaluated pancreatitis cases and their course. Read More

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October 2021

The Electronic Frailty Index is Associated with Increased Infection and All-Cause Mortality Among Older Patients with Primary Lung Cancer: A Cohort Study.

Clin Interv Aging 2021 11;16:1825-1833. Epub 2021 Oct 11.

The Center of Gerontology and Geriatrics/National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.

Introduction: To assess whether the electronic frailty index (eFI) is independently associated with all-cause mortality and chemotherapy adverse reactions among older Chinese patients with lung cancer.

Methods: This is a retrospective, single-institution, chart review, and not a prospective cohort study. All patients ≥60 years with primary lung cancer in the West China Hospital from 2010 to 2017 were included in this cohort. Read More

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October 2021

Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst Rev 2021 Oct 21;10:CD001146. Epub 2021 Oct 21.

Retired Honorary Professor of Child Health, Queen's University Belfast, Belfast, UK.

Background: Bronchopulmonary dysplasia (BPD) remains a major problem for infants born extremely preterm. Persistent inflammation in the lungs is important in its pathogenesis. Systemic corticosteroids have been used to prevent or treat BPD because of their potent anti-inflammatory effects. Read More

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October 2021

A short chain fatty acid-centric view of Clostridioides difficile pathogenesis.

PLoS Pathog 2021 Oct 21;17(10):e1009959. Epub 2021 Oct 21.

Department of Medicine, University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin, United States of America.

Clostridioides difficile is an opportunistic diarrheal pathogen responsible for significant morbidity and mortality worldwide. A disrupted (dysbiotic) gut microbiome, commonly engendered by antibiotic treatment, is the primary risk factor for C. difficile infection, highlighting that C. Read More

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October 2021

Metagenomic Next-Generation Sequencing in the Diagnosis of HHV-1 Reactivation in a Critically Ill COVID-19 Patient: A Case Report.

Front Med (Lausanne) 2021 4;8:715519. Epub 2021 Oct 4.

The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China.

Secondary infections pose tremendous challenges in Coronavirus disease 2019 (COVID-19) treatment and are associated with higher mortality rates. Clinicians face of the challenge of diagnosing viral infections because of low sensitivity of available laboratory tests. A 66-year-old woman initially manifested fever and shortness of breath. Read More

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October 2021

Fulminant Haemolysis Following Endoscopic Retrograde Cholangiopancreatography.

Eur J Case Rep Intern Med 2021 1;8(9):002811. Epub 2021 Sep 1.

Clinical Pathology Department, Hospital Pedro Hispano, Porto, Portugal.

We report the case of a 77-year-old-man with a history of type 2 diabetes mellitus who underwent endoscopic retrograde cholangiopancreatography (ERCP) because of a gallstone in the common bile duct. Thirty-six hours after the procedure, the patient developed persistent fever and epigastric pain associated with de novo jaundice. Massive haemolysis (with exuberant spherocytosis) occurred and patient died in 3 hours. Read More

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September 2021

Shared Physiologic Pathways Among Comorbidities for Adults With Cerebral Palsy.

Front Neurol 2021 4;12:742179. Epub 2021 Oct 4.

Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, United States.

Aging with cerebral palsy is accompanied by a declining health and function status across neurological and non-neurological systems. There is a need to understand the shared pathophysiology among comorbidities for adults with cerebral palsy, to inform clinical assessment and guidelines for interventions to improve healthful aging. To begin defining multimorbidity, this study identified the most common comorbidity combinations and their association with mortality among a representative sample of adults with cerebral palsy. Read More

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October 2021

Predictive scoring systems for in-hospital mortality due to acutely decompensated liver cirrhosis in Indonesia.

BMC Gastroenterol 2021 Oct 20;21(1):392. Epub 2021 Oct 20.

Hepatobiliary Division, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia.

Background: Acutely decompensated liver cirrhosis is associated with high medical costs and negatively affects productivity and quality of life. Data on factors associated with in-hospital mortality due to acutely decompensated liver cirrhosis in Indonesia are scarce. This study aims to identify predictors of in-hospital mortality and develop predictive scoring systems for clinical application in acutely decompensated liver cirrhosis patients. Read More

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October 2021

Diagnosis of the misdiagnosed: Mucormycosis depicting periodontitis.

J Indian Soc Periodontol 2021 Sep-Oct;25(5):443-447. Epub 2021 Aug 30.

Department of Oral Medicine and Radiology, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

Oral cavity is habitat for plethora of micro-organism causing various diseases. The most common includes dental caries, periodontal diseases, etc. Dental practice may rarely encounter unusual and subtle symptoms with nonpathognomonic clinical signs of several fatal diseases which may pretend like a common oral disease. Read More

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Efficacy of left ventricular unloading strategies during venoarterial extracorporeal membrane oxygenation in patients with cardiogenic shock: a protocol for a systematic review and Bayesian network meta-analysis.

BMJ Open 2021 Oct 19;11(10):e047046. Epub 2021 Oct 19.

Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, Gansu, China

Introduction: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been widely used for patients with refractory cardiogenic shock. A common side effect of this technic is the resultant increase in left ventricular (LV) afterload which could potentially aggravate myocardial ischaemia, delay ventricular recovery and increase the risk of pulmonary congestion. Several LV unloading strategies have been proposed and implemented to mitigate these complications. Read More

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October 2021

[Investigation of the Relationship of Systemic Immune-Inflammation Index, C-Reactive Protein and Interleukin-6 with Viral Dynamics in Patients with COVID-19].

Mikrobiyol Bul 2021 Oct;55(4):539-552

Ankara City Hospital, Clinic of Medical Microbiology, Ankara, Turkey.

Coronaviruses are enveloped, positivepolarity, single-stranded RNA viruses that can cause respiratory and gastrointestinal tract infections, less likely to cause infections with hepatic, neurological and nephrotic involvement. A novel coronavirus termed as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the city of Wuhan, China, and caused an outbreak of unusual viral pneumonia at the end of 2019. This study aimed to reveal the relationship between systemic immune-inflammation index (SII), C-reactive protein (CRP) and interleukin-6 (IL-6) and viral dynamics in COVID-19 patients. Read More

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October 2021

Impact of renin-angiotensin-aldosterone system inhibition on morbidity and mortality during long-term continuous-flow left ventricular assist device support: An IMACS report.

J Heart Lung Transplant 2021 Sep 9. Epub 2021 Sep 9.

Cardiovascular Division, Tufts Medical Center, Boston, Massachusetts.

Background: Inhibition of the renin angiotensin aldosterone system (RAAS) improves survival and reduces adverse cardiac events in heart failure with reduced ejection fraction, but the benefit is not well-defined following left ventricular assist device (LVAD).

Methods: We analyzed the ISHLT IMACS registry for adults with a primary, continuous-flow LVAD from January 2013 to September 2017 who were alive at postoperative month 3 without a major adverse event, and categorized patients according to treatment an angiotensin converting enzyme inhibitor (ACEI/ARB) or mineralocorticoid receptor antagonist (MRA). Propensity score matching was performed separately for ACEI/ARB vs none (n = 4,118 each) and MRA vs none (n = 3,892 each). Read More

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September 2021

A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT.

Health Technol Assess 2021 Oct;25(58):1-86

Department of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK.

Background: Tranexamic acid reduces blood loss in surgery and the risk of death in trauma patients. Meta-analyses of small trials suggest that tranexamic acid decreases the number of deaths from gastrointestinal bleeding, but these meta-analyses are prone to selection bias.

Objective: The trial provides reliable evidence of the effect of tranexamic acid on mortality, rebleeding and complications in significant acute gastrointestinal bleeding. Read More

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October 2021

Intestinal dehiscence and mortality in cats undergoing gastrointestinal surgery.

J Feline Med Surg 2021 Oct 19:1098612X211048454. Epub 2021 Oct 19.

Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA, USA.

Objectives: The aim of this study was to determine the incidence of and risk factors for both gastrointestinal (GI) incisional dehiscence and mortality in a large cohort of cats undergoing GI surgery. We hypothesized that cats with preoperative septic peritonitis (PSP), systemic inflammatory response syndrome (SIRS) or sepsis would have higher GI dehiscence and mortality rates than unaffected cats.

Methods: A medical records search identified cats with surgically created, full-thickness incisions into their stomach, small intestines or large intestines. Read More

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October 2021

Treatment Effect of Percutaneous Coronary Intervention in Dialysis Patients With ST-Elevation Myocardial Infarction.

Am J Kidney Dis 2021 Oct 15. Epub 2021 Oct 15.

Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN. Electronic address:

Rationale & Objective: Patients receiving maintenance dialysis have higher mortality following primary percutaneous coronary intervention (pPCI) than patients not receiving dialysis. Whether pPCI confers a similar benefit to patients receiving dialysis remains unknown. We compared the effect of pPCI on in-hospital outcomes among patients hospitalized for STEMI and receiving maintenance dialysis to the effect among patients hospitalized for STEMI but not receiving dialysis. Read More

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October 2021

Lipoprotein Z, A novel hepatotoxic lipoprotein, predicts outcome in alcoholic hepatitis.

Hepatology 2021 Oct 18. Epub 2021 Oct 18.

Laboratory Corporation of America Holdings (Labcorp), Morrisville, NC, USA.

Background & Aims: Lipoprotein Z (LP-Z) is an abnormal free cholesterol (FC)-enriched low density lipoprotein (LDL)-like particle discovered from patients with cholestatic liver disease. This study aims to define the diagnostic value of LP-Z in alcoholic hepatitis (AH) and interrogate the biology behind its formation.

Approach & Results: We measured serum levels of LP-Z using nuclear magnetic resonance spectroscopy, a well-established clinical assay. Read More

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October 2021

Systematic review and meta-analysis of risk scores in prediction for the clinical outcomes in patients with acute variceal bleeding.

Ann Med 2021 Dec;53(1):1806-1815

Department of Gastroenterology, Zhong Da Hospital, Medical School, Southeast University, Nanjing, PR China.

Background: Acute variceal bleeding (AVB) is a life-threatening condition that needs risk stratification to guide clinical treatment. Which risk system could reflect the prognosis more accurately remains controversial. We aimed to conduct a meta-analysis of the predictive value of GBS, AIMS65, Rockall (clinical Rockall score and full Rockall score), CTP and MELD. Read More

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December 2021

Association Between Helicobacter pylori Infection and Serum Iron Profile.

Cureus 2021 Sep 13;13(9):e17925. Epub 2021 Sep 13.

Family Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.

Introduction: Helicobacter pylori (H. pylori) infection is reported to be the most frequent cause of morbidity and mortality in cases of upper gastrointestinal (GI) diseases. There is paucity of research between the possible association of H. Read More

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September 2021

Outcomes of Non-metastatic Colon Cancer: A Single-Center Experience.

Cureus 2021 Sep 1;13(9):e17657. Epub 2021 Sep 1.

Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.

Background Colorectal cancer (CRC) is the most common gastrointestinal cancer. In the Saudi Cancer Registry, CRC ranked as the most common cancer in men and the third most common cancer in women. Data regarding the stage of CRC at presentation and patient demographics and outcomes in Saudi Arabia are lacking. Read More

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September 2021

COVID-19 and liver injury: role of inflammatory endotheliopathy, platelet dysfunction and thrombosis.

Hepatol Commun 2021 Oct 18. Epub 2021 Oct 18.

Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.

Liver injury, characterized predominantly by elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT), is a common feature of coronavirus disease-2019 (COVID-19) symptom caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2). Additionally, SARS-CoV2 infection is associated with acute-on-chronic liver failure in patients with cirrhosis, and has a notably elevated mortality in patients with alcohol-related liver disease compared to other etiologies. Direct viral infection of the liver with SARS-CoV2 remains controversial, and alternative pathophysiologic explanations for its hepatic effects are an area of active investigation. Read More

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October 2021

Incidence and Treatment of Splanchnic Vein Thrombosis in Patients with Acute Pancreatitis: A Systematic Review and Meta-analysis.

J Gastroenterol Hepatol 2021 Oct 17. Epub 2021 Oct 17.

Gastrointestinal Surgery, Nottingham Digestive Diseases Centre and National Institute for Health Research Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Queen's Medical Centre, Nottingham, UK.

Background And Aims: This meta-analysis aimed to estimate the incidence of splanchnic vein thrombosis (SVT) in patients with acute pancreatitis and assess the effects of therapeutic anticoagulation.

Methods: Systematic searches of the Medline, Embase and Cochrane databases were undertaken to identify studies reporting the incidence and outcomes associated with SVT in patients with acute pancreatitis. The pooled incidence, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using a random effects model. Read More

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October 2021