838,640 results match your criteria mood


An Analysis of the Effect of selected Factors on microsurgical Performance.

Handchir Mikrochir Plast Chir 2021 Sep 27. Epub 2021 Sep 27.

Pomeranian Medical University, Students' Scientific Circle at Department of General and Hand Surgery.

Background: Microsurgery is a specific surgical expertise that involves operating on very small structures, and requires the assistance of a magnifying device: a microscope or loupes. Several factors have been identified that could affect the quality of microsurgical performance in training or surgical procedures.

Objective: The objective of this study was to assess the impact of the selected factors - caffeine, alcohol and physical exercise - on a microsurgical task prior its performance. Read More

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September 2021

Autobiographical Script-Driven Imagery Has No Detectable Effect on Emotion Regulation in Healthy Individuals.

Neuropsychobiology 2021 Sep 27:1-8. Epub 2021 Sep 27.

Department of Psychiatry and Neurosciences, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Introduction: Emotion regulation (ER), the ability to actively modulate one's own emotion reactions, likely depends on the individual's current emotional state. Here, we investigated whether negative emotions induced by an interpersonal autobiographic script affect the neuronal processes underlying ER.

Methods: Twenty healthy participants were recruited and underwent functional magnetic resonance imaging (fMRI) during performance of distancing, a specific ER strategy, while viewing emotionally arousing pictures. Read More

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September 2021

Sleep in times of crises: A scoping review in the early days of the COVID-19 crisis.

Sleep Med Rev 2021 Sep 8;60:101545. Epub 2021 Sep 8.

École de Psychologie, Université Laval, Québec (Québec), Canada; CERVO Brain Research Center, Université Laval, Canada. Electronic address:

During the early days of the pandemic and in the context of a seemingly unknown global threat, several potential major sleep disruptors were identified by sleep researchers and practitioners across the globe. The COVID-19 pandemic combined several features that, individually, had been shown to negatively affect sleep health in the general population. Those features included state of crisis, restrictions on in-person social interactions, as well as financial adversity. Read More

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September 2021

Multimedia distributions and the fate of microcystins from freshwater discharge in the Geum River Estuary, South Korea: Applicability of POCIS for monitoring of microalgal biotoxins.

Environ Pollut 2021 Sep 22;291:118222. Epub 2021 Sep 22.

Department of Marine Sciences and Convergence Engineering, Hanyang University, Ansan 15588, Republic of Korea.

Here, we investigated the characteristics of the environmental multimedia distribution of microcystins (MCs) introduced from freshwater discharge through the estuary dam of the Geum River. In addition, the applicability of a passive sampling device (polar organic chemical integrative sampler, POCIS) for monitoring MCs was evaluated. Surface water, suspended solids (SS), sediments, and oysters were collected from the inner and outer estuary dam. Read More

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September 2021

Ammonium regulates redox homeostasis and photosynthetic ability to mitigate copper toxicity in wheat seedlings.

Ecotoxicol Environ Saf 2021 Sep 24;226:112825. Epub 2021 Sep 24.

Triticeae Research Institute, Sichuan Agricultural University, Wenjiang 611130, Sichuan, China.

As an essential plant micronutrient, copper (Cu) is required as a component of several enzymes, but it can be highly toxic to plants when present in excess quantities. Nitrogen (N) application can help to alleviate the phytotoxic effects of heavy metals, including Cu, and different N forms significantly affect the uptake and accumulation of heavy metals in plants. The aim of this study was to determine the effects of different N forms, i. Read More

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September 2021

Levonorgestrel and dydrogesterone affect sex determination via different pathways in zebrafish.

Aquat Toxicol 2021 Sep 21;240:105972. Epub 2021 Sep 21.

SCNU Environmental Research Institute, Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety & MOE Key Laboratory of Theoretical Chemistry of Environment, South China Normal University, Guangzhou 510006, China; School of Environment, South China Normal University, University Town, Guangzhou 510006, China. Electronic address:

Levonorgestrel (LNG) and dydrogesterone (DDG) are two commonly used synthetic progestins that have been detected in aquatic environments. They could affect fish sex differentiation, but the underlying mechanisms remain unknown. Here we investigated the effects of LNG (5 ng L and 50 ng L), DDG (100 ng L) and their mixtures on gonadal differentiation and sex determination in zebrafish at transcriptomic and histological levels from 2 hours post-fertilization (eleutheroembryos) to 144 days post-fertilization (sexual maturity). Read More

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September 2021

Psychological distress, rumination and problematic smartphone use among Spanish adolescents: An emotional intelligence-based conditional process analysis.

J Affect Disord 2021 Sep 16;296:1-8. Epub 2021 Sep 16.

Faculty of Psychology, University of Málaga.

Background: Problematic smartphone use (PSU) is a public health issue that is currently rising among adolescents. The Compensatory Internet Use Theory (CIUT) poses that difficulties in handling negative life circumstances could result in PSU. Furthermore, the Interaction of Person-Affect-Cognition-Execution (I-PACE) model suggests that the interaction between core characteristics and affective and cognitive responses could lead to PSU. Read More

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September 2021

Assessment of hydrogeochemical characteristics and saltwater intrusion in selected coastal aquifers of southwestern India.

Mar Pollut Bull 2021 Sep 24;173(Pt A):112989. Epub 2021 Sep 24.

Department of Civil Engineering, Manipal Academy of Higher Education, Manipal 576104, India.

The principal objective of this study is to assess the saltwater intrusion and hydrogeochemical processes that affect groundwater geochemistry in the coastal aquifers of southwestern India. Groundwater samples were collected seasonally and the physico-chemical parameters determined on-site. Major ions were determined in the laboratory. Read More

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September 2021

Time since SARS-CoV-2 infection and humoral immune response following BNT162b2 mRNA vaccination.

EBioMedicine 2021 Sep 24;72:103589. Epub 2021 Sep 24.

Department of Internal Medicine, Amsterdam UMC, Amsterdam Institute for Infection and Immunity, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam 1081 HV, the Netherlands. Electronic address:

Background: To optimise the use of available SARS-CoV-2 vaccines, some advocate delaying second vaccination for individuals infected within six months. We studied whether post-vaccination immune response is equally potent in individuals infected over six months prior to vaccination.

Methods: We tested serum IgG binding to SARS-CoV-2 spike protein and neutralising capacity in 110 healthcare workers, before and after both BNT162b2 messenger RNA (mRNA) vaccinations. Read More

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September 2021

A transdiagnostic evaluation of cortical inhibition in severe mental disorders using Transcranial Magnetic Stimulation.

J Psychiatr Res 2021 Sep 24;143:364-369. Epub 2021 Sep 24.

Department of Psychiatry, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, 560029, India.

Multiple lines of investigations suggest the presence of cortical inhibition aberrations as central to the phenotypic manifestations of severe mental disorders. Transcranial Magnetic Stimulation (TMS) combined with electromyography can characterize these inhibitory processes in the motor cortex with satisfactory temporal precision. We examined TMS-evoked short- (SICI) and long-interval intracortical inhibition (LICI) and cortical silent period (CSP) as markers of GABA- (SICI) and GABA-mediated (LICI and CSP) cortical neurotransmission in symptomatic individuals with mania (n = 40), schizophrenia (n = 76), unipolar depression (n = 86), and OCD (n = 43), and compared them against similar recordings in healthy subjects (n = 125). Read More

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September 2021

Zeta potential of CO-rich aqueous solutions in contact with intact sandstone sample at temperatures of 23 °C and 40 °C and pressures up to 10.0 MPa.

J Colloid Interface Sci 2021 Sep 17;607(Pt 2):1226-1238. Epub 2021 Sep 17.

University of Aberdeen, School of Engineering, Elphinstone Road, AB24 3UE Aberdeen, United Kingdom. Electronic address:

Despite the broad range of interest and applications, controls on the electric surface charge and the zeta potential of silica in contact with aqueous solutions saturated with dissolved CO at conditions relevant to natural systems, remains unreported. There have been no published zeta potential measurements conducted in such systems at equilibrium, hence the effect of composition, pH, temperature and pressure remains unknown. We describe a novel methodology developed for the streaming potential measurements under these conditions, and report zeta potential values for the first time obtained with Fontainebleau sandstone core sample saturated with carbonated NaCl, NaSO, CaCl and MgCl solutions under equilibrium conditions at pressures up to 10 MPa and temperatures up to 40 °C. Read More

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September 2021

Interplay of distributions of multiple guest molecules in block copolymer micelles: A dissipative particle dynamics study.

J Colloid Interface Sci 2021 Sep 13;607(Pt 2):1142-1152. Epub 2021 Sep 13.

School of Materials Science and Engineering, China University of Petroleum (East China), Qingdao, Shandong 266580, PR China; Institute of Advanced Materials, China University of Petroleum (East China), Qingdao, Shandong 266580, PR China. Electronic address:

Hypothesis: Delivery of multiple payloads using the same micelle is of significance to achieve multifunctional or synergistic effects. The interacting distribution of different payloads in micelles is expected to influence the loading stability and capacity. It is highly desirable to explore how intermolecular interactions affect the joint distribution of multi-payloads. Read More

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September 2021

How do the printing parameters of Fused Filament Fabrication and structural voids influence the degradation of biodegradable devices?

Acta Biomater 2021 Sep 24. Epub 2021 Sep 24.

National Engineering Research Centre for High Efficiency Grinding, Hunan University, 410082, China; State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body, Hunan University, 410082, China. Electronic address:

Fused Filament Fabrication (FFF), a commonly used additive manufacturing technology, is now employed widely in biomedical fields for fabricating geometrically complex biodegradable devices. Structural voids arising from the printing process exist within the objects manufactured by FFF. This paper reveals the underlying mechanism of how the printing parameters and voids affect the degradation behaviours of devices made of biodegradable polyesters. Read More

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September 2021

Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells.

Mitochondrion 2021 Sep 24. Epub 2021 Sep 24.

Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India; Special Centre for Systems Medicine, Jawaharlal Nehru University, New Delhi, India. Electronic address:

The weightlessness or microgravity, a physical factor in space, may adversely affect the health of the space travellers or astronauts. The knowledge about the effect of microgravity on human cancer cells is very limited and poorly understood. Here, we employed rotary cell culture system (RCCS) to induce simulated microgravity (SMG) and examined its effects on human promyelocytic leukemic HL-60 cells. Read More

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September 2021

Elevated CO, warming, N addition, and increased precipitation affect different aspects of the arbuscular mycorrhizal fungal community.

Sci Total Environ 2021 Sep 22;806(Pt 1):150522. Epub 2021 Sep 22.

International Joint Research Laboratory for Global Change Ecology, School of Life Sciences, Henan University, Kaifeng,475004, Henan, China; Yellow River Floodplain Ecosystems Research Station, Henan University, Xingyang, China. Electronic address:

The functional diversity of arbuscular mycorrhizal fungi (AMF) affects the resistance and resilience of plant communities to environmental stress. However, considerable uncertainty remains regarding how the complex interactions among elevated atmospheric CO (eCO), nitrogen deposition (eN), precipitation (eP), and warming (eT) affect AMF communities. These global change factors (GCFs) do not occur in isolation, and their interactions likely affect AMF community structure and assembly processes. Read More

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September 2021

Key concepts in clinical epidemiology: addressing and reporting sources of bias in randomised controlled trials.

J Clin Epidemiol 2021 Sep 24. Epub 2021 Sep 24.

Department of Behavioural Science and Health, University College London, London, United Kingdom.

Randomised controlled trials are widely considered the most robust design for evaluating the effects of clinical interventions. While generalisability is often limited, randomisation aims to ensure that effects observed are genuine. However, there are common sources of bias, even in well-conducted trials, that pose a threat to this interpretation. Read More

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September 2021

Linking pupil size modulated by global luminance and motor preparation to saccade behavior.

Neuroscience 2021 Sep 24. Epub 2021 Sep 24.

Institute of Cognitive Neuroscience, National Central University, Taoyuan City, Taiwan; Cognitive Intelligence and Precision Healthcare Center, National Central University, Taoyuan City, Taiwan; Department of Psychology, Kaohsiung Medical University, Kaohsiung City, Taiwan.

Saccades are rapid eye movements that are used to move the high acuity fovea in a serial manner in the exploration of the visual scene. Stimulus contrast is known to modulate saccade latency and metrics possibly via changing visual activity in the superior colliculus, a midbrain structure causally involved in saccade generation. However, the quality of visual signals should also be modulated by the amount of lights projected onto the retina, which is gated by the size of the pupil. Read More

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September 2021

Oxytocin system driven by experiences modifies social recognition and neuron morphology in female BALB/c mice.

Peptides 2021 Sep 24:170659. Epub 2021 Sep 24.

Institute of Anatomy and Histology & Embryology, Neuroscience, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, 730000, PR China; Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, Lanzhou, Gansu, 730000, PR China. Electronic address:

The oxytocin (OT) system, affected by life experiences, modulates neuron morphology in a sex-specific manner, leading to sex differences in social interactions. To date, few studies have focused on the OT system and social interactions of female mice. In this study, we used maternal deprivation (MD) and its possible treatment, environmental enrichment (EE), to affect social recognition in female BALB/c mice. Read More

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September 2021

Markers of the sympathetic, parasympathetic and sensory nervous system are altered in the human diabetic choroid.

Peptides 2021 Sep 24:170661. Epub 2021 Sep 24.

Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie-fang Road, Wuhan, Hubei Province, People's Republic of China. Electronic address:

Background: We sought to evaluate alterations in markers of the autonomic nervous system in human diabetic choroid.

Methods: Eighteen eyeballs from subjects with diabetes and 22 eyeballs from subjects without diabetes were evaluated in this study. Synaptophysin, tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DβH), neuronal nitric oxide synthase (nNOS), choline acetyltransferase (ChAT), vesicular monoamine transporter II (VMAT-2), vesicular acetylcholine transporter (VAChT), vasoactive intestinal peptide (VIP), neuropeptide Y (NPY), and calcitonin gene-related peptide (CGRP) levels were detected by western blot analysis and immunofluorescence was performed in some cases. Read More

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September 2021

Efficacy Evaluation of Temporomandibular Arthroscopic-Assisted Masseter Nerve Avulsion on Hemimasticatory Spasm.

J Oral Maxillofac Surg 2021 Aug 28. Epub 2021 Aug 28.

Professor, Department of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China. Electronic address:

Purpose: Hemimasticatory spasm (HMS) is a masticatory muscle disorder without an effective treatment approach at present. This retrospective analysis aims to investigate the clinical efficacy of temporomandibular arthroscope-assisted masseteric nerve avulsion on HMS and thereby further determine a more effective therapeutic strategy for HMS patients.

Methods: Four patients with HMS receiving temporomandibular arthroscope-assisted masseteric nerve avulsion in the neurology department of oral surgery of our hospital from April 2017 to April 2018 were recruited in this study. Read More

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Uptake and accumulation of microplastic particles by two freshwater ciliates isolated from a local river in South Africa.

Environ Res 2021 Sep 24:112123. Epub 2021 Sep 24.

Discipline of Microbiology, School of Life Sciences, University of KwaZulu-Natal, Private Bag X01, Pietermaritzburg, 3209, South Africa. Electronic address:

Microplastics are considered environmental pollutants of serious concern. In freshwater environments, they can affect aquatic biota and accumulate along the food web. Therefore, this study investigated the capacity of bacterivorous freshwater ciliates, essential members of the aquatic food chain, to ingest plain and fluorescently-labeled polystyrene microspheres. Read More

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September 2021

Behavioral Health Diagnoses in Youth With Gender Dysphoria Compared with Controls: A PEDSnet Study.

J Pediatr 2021 Sep 24. Epub 2021 Sep 24.

University of Colorado Anschutz Medical Campus, Aurora, CO. Electronic address:

Objective: To assess the odds of a psychiatric or neurodevelopmental diagnosis among youth with a diagnosis of gender dysphoria compared with matched controls in a large electronic health record dataset from six pediatric health systems, PEDSnet. We hypothesized that youth with gender dysphoria would have higher odds of having psychiatric and neurodevelopmental diagnoses than controls.

Study Design: All youth with a diagnosis of gender dysphoria (n=4,173 age at last visit 16. Read More

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September 2021

Social and environmental effects of the COVID-19 pandemic on children.

J Pediatr (Rio J) 2021 Sep 20. Epub 2021 Sep 20.

Pontifícia Universidade Católica do Rio Grande do Sul, Escola de Medicina, Núcleo de Neurociências and Instituto do Cérebro (InsCer), Porto Alegre, RS, Brazil.

Objective: This study aimed to review the literature, summarizing the existing evidence on the effects of the pandemic on children, adolescents and parents, with an emphasis on the psychological, emotional, and sleep quality consequences.

Source Of Data: Empirical studies identified in the following databases: MEDLINE, ISI Web of Knowledge/Web of Science, and preprint servers.

Synthesis Of Data: The findings point to a wide range of consequences for children and adolescents resulting from the COVID-19 pandemic, which mainly includes an increase in depressive mood symptoms. Read More

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September 2021

THE RELATIVE REINFORCING VALUE OF SNACK FOOD IS A SIGNIFICANT PREDICTOR OF FAT LOSS IN WOMEN WITH OVERWEIGHT OR OBESITY.

Appl Physiol Nutr Metab 2021 Sep 27. Epub 2021 Sep 27.

Children's Hospital of Eastern Ontario, 27338, Research Institute, Ottawa, Ontario, Canada;

Reinforcing Relative Value (RRV) of food and impulsivity are associated with energy intake and obesity. The study investigated the degree to which changes in RRV and impulsivity independently or interactively predict change in body weight and composition in women with overweight or obesity engaged in either a fast or in a slow weight loss programs. Body weight, body composition, Impulsivity (Barratt Impulsiveness Scale), RRV snack (computerized Behavioural Choice Task) were measured at baseline and post-intervention in 30 women with obesity undergoing either slow (n= 14 -500 kcal/day, 20 weeks) or fast n=16 (-1000kcal/day, 10 weeks) weight reduction. Read More

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September 2021

Geographical sampling bias on the assessment of endemism areas for marine meiobenthic fauna.

Cladistics 2021 Oct 5;37(5):571-585. Epub 2021 Mar 5.

Department of Biological Science, Federal University of Jequitinhonha and Mucuri Valleys, Minas Gerais, Brazil.

Species distribution patterns are constrained by historical and ecological processes in space and time, but very often the species range sizes are geographical sampling biases resulting from unequal sampling effort. One of the most common definitions of endemism is based on the "congruence of distributional areas" criterion, when two or more species have the same distributional limits. By acknowledging that available data of marine meiobenthic species are prone to geographical sampling bias and that can affect the accuracy of the biogeographical signals, the present study combines analyses of inventory incompleteness and recognition of spatial congruence of Gastrotricha, Kinorhyncha, meiobenthic Annelida and Tardigrada in order to better understand the large-scale distribution of these organisms in coastal and shelf areas of the world. Read More

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October 2021

Computerized history-taking improves data quality for clinical decision-making-Comparison of EHR and computer-acquired history data in patients with chest pain.

PLoS One 2021 27;16(9):e0257677. Epub 2021 Sep 27.

Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden.

Patients' medical histories are the salient dataset for diagnosis. Prior work shows consistently, however, that medical history-taking by physicians generally is incomplete and not accurate. Such findings suggest that methods to improve the completeness and accuracy of medical history data could have clinical value. Read More

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September 2021

Meta-analysis of transcriptomic data reveals clusters of consistently deregulated gene and disease ontologies in Down syndrome.

PLoS Comput Biol 2021 Sep 27;17(9):e1009317. Epub 2021 Sep 27.

Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain.

Trisomy of human chromosome 21 (HSA21) causes Down syndrome (DS). The trisomy does not simply result in the upregulation of HSA21--encoded genes but also leads to a genome-wide transcriptomic deregulation, which may differently affect each tissue and cell type as results of epigenetic mechanisms and protein-protein interactions. We performed a meta-analysis integrating the differential expression (DE) analyses of all publicly available transcriptomic datasets, both in human and mouse, comparing trisomic and euploid transcriptomes from different sources. Read More

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September 2021

A broad analysis of splicing regulation in yeast using a large library of synthetic introns.

PLoS Genet 2021 Sep 27;17(9):e1009805. Epub 2021 Sep 27.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

RNA splicing is a key process in eukaryotic gene expression, in which an intron is spliced out of a pre-mRNA molecule to eventually produce a mature mRNA. Most intron-containing genes are constitutively spliced, hence efficient splicing of an intron is crucial for efficient regulation of gene expression. Here we use a large synthetic oligo library of ~20,000 variants to explore how different intronic sequence features affect splicing efficiency and mRNA expression levels in S. Read More

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September 2021

Polymorphisms in BMPRIB gene affect litter size in Chinese indigenous sheep breed.

Anim Biotechnol 2021 Sep 27:1-8. Epub 2021 Sep 27.

College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.

The BMPRIB gene belongs to the TGF-β superfamily and is considered to be a regulator of sheep reproductive performance. Single nucleotide polymorphisms (SNPs) of BMPRIB gene in the Small Tail Han, Hu, Mongolian, Oula, Gansu Alpine Fine-wool, Dorper and Australian White sheep were detected by Sanger sequencing. Five SNPs (rs427897187 G > A, rs418841713 A > G, rs159952533 T > C, rs429416173 C > A and rs403555643 A > G) of BMPRIB gene were identified. Read More

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September 2021

Psychometric features of brief pain inventory for Parkinson's disease during medication states.

Disabil Rehabil 2021 Sep 27:1-6. Epub 2021 Sep 27.

Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.

Purpose: Patients with idiopathic Parkinson's disease (PD) suffer from different non-motor symptoms, including pain. The present study aimed to measure the psychometric properties of the Brief Pain Inventory (BPI) in patients with PD during ON- and OFF-states.

Methods: We recruited 460 patients with PD and 100 non-PD controls. Read More

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September 2021