540 results match your criteria months nocturia


Low-Intensity Extracorporeal Shock Wave Therapy Promotes Bladder Regeneration and Improves Overactive Bladder Induced by Ovarian Hormone Deficiency from Rat Animal Model to Human Clinical Trial.

Int J Mol Sci 2021 Aug 27;22(17). Epub 2021 Aug 27.

Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Postmenopausal women with ovary hormone deficiency (OHD) are subject to overactive bladder (OAB) symptoms. The present study attempted to elucidate whether low-intensity extracorporeal shock wave therapy (LiESWT) alters bladder angiogenesis, decreases inflammatory response, and ameliorates bladder hyperactivity to influence bladder function in OHD-induced OAB in human clinical trial and rat model. The ovariectomized (OVX) for 12 months Sprague-Dawley rat model mimicking the physiological condition of menopause was utilized to induce OAB and assess the potential therapeutic mechanism of LiESWT (0. Read More

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The diagnostic and therapeutic efficacy of cystoscopy with hydrodistension and random biopsies in clinically suspected interstitial cystitis/bladder pain syndrome.

Eur J Obstet Gynecol Reprod Biol 2021 Aug 27;265:156-161. Epub 2021 Aug 27.

Department of Urology, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing 100034, China. Electronic address:

Objective: We aimed to explore the diagnostic and therapeutic efficacy of cystoscopy with hydrodistension and random biopsies for clinically suspected interstitial cystitis/bladder pain syndrome (IC/BPS).

Study Design: We reviewed the data of fifty-five clinically suspected IC/BPS patients underwent cystoscopy with hydrodistension and random biopsies. Global Response Assessment was used to evaluate the efficacy. Read More

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Real-life patient experiences of TTNS in the treatment of overactive bladder syndrome.

Ther Adv Urol 2021 Jan-Dec;13:17562872211041470. Epub 2021 Aug 31.

Radboudumc, Nijmegen, Netherlands.

Introduction And Objectives: Overactive bladder syndrome (OAB) is defined as urinary urgency, with or without urgent urinary incontinence; it is often associated with urinary frequency and nocturia, in the absence of any pathological or metabolic conditions that may cause or mimic OAB. The aim of this study was to evaluate the long-term real-life adherence of transcutaneous tibial nerve stimulation (TTNS) in the treatment of OAB, patient satisfaction of the treatment, and reasons for quitting therapy.

Materials And Methods: In this single center study, all patients who had a positive effect on percutaneous tibial nerve stimulation (PTNS) and continued to receive home-based treatment with TTNS since 2012 were included for analysis. Read More

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Urge suppression and modified fluid consumption in the management of female overactive bladder symptoms.

Urol Ann 2021 Jul-Sep;13(3):263-267. Epub 2021 Jul 14.

Department of Obstetrics and Gynecology, Katihar Medical College, Katihar, Bihar, India.

Background: At the initial management of overactive bladder (OAB) syndrome urge suppression technique along with other behavioural modification could be a good option.

Methods: Prospective experimental study conducted between 2015 and 2019. Women complaining of OAB were enrolled. Read More

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"Puddles on the Road": Hurdles in the Pathway from Symptoms to Diagnosis and Treatment in Children with Type 1 Diabetes.

Indian J Endocrinol Metab 2021 Jan-Feb;25(1):23-30. Epub 2021 Jul 21.

Endocrinology and Diabetes Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: This study was conducted to investigate the pathway from first symptoms to initiation of insulin regimen in children with new-onset Type 1 Diabetes Mellitus (T1DM) and explore the reasons behind diabetes ketoacidosis (DKA) at onset among children with T1DM.

Materials And Methods: An exploratory study was conducted using a pretested questionnaire, among parents of children diagnosed with T1DM within preceding 3 months.

Results: Out of the total 105 children, 56. Read More

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[Evolution of the USP and IPSS score after continuous positive airway pressure sleep apnea therapy at night].

Prog Urol 2021 Jun 19. Epub 2021 Jun 19.

Service d'urologie, clinique Pasteur, 17200 Royan, France.

Introduction: To assess the impact of nocturnal continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA) on lower urinary tract (LUTS) symptoms.

Materials And Methods: A prospective, monocentric study was conducted between June 2018 and August 2019. Patients with moderate to severe OSA with an indication for treatment with nocturnal CPAP in combination with SBAU were included. Read More

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Adding mirabegron after intravesical onabotulinumtoxinA injection improves therapeutic effects in patients with refractory overactive bladder.

Low Urin Tract Symptoms 2021 May 6. Epub 2021 May 6.

Department of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, and Buddhist Tzu Chi University, Hualien, Taiwan.

Objectives: To investigate whether adding an anticholinergic or beta-3 agonist can improve the therapeutic effect of intravesical onabotuliumtoxinA injection in patients with refractory overactive bladder (OAB).

Methods: Ninety OAB patients who received an intravesical 100-U onabotulinumtoxinA injection 1 month previously were consecutively invited into a prospective, randomized, open-label study. They were randomly adding on solifenacin 5 mg daily (QD) (30 patients), mirabegron 50 mg QD (31 patients), or no medication (29 patients, control). Read More

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Is coronavirus disease 2019 associated with indicators of long-term bladder dysfunction?

Neurourol Urodyn 2021 06 4;40(5):1200-1206. Epub 2021 May 4.

Department of Urology, Moinhos de Vento Hospital, Porto Alegre, Brazil.

Objective: Early reports have suggested that coronavirus disease 2019 (COVID-19) can present with significant urinary frequency and nocturia, and that these symptoms correlate with markers of inflammation in the urine. We evaluated surrogate markers of chronic urinary symptoms to determine if they were more frequent after COVID-19 infection.

Methods: Routinely collected data from the province of Ontario was used to conduct a matched, retrospective cohort study. Read More

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Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up.

Front Oncol 2021 15;11:641887. Epub 2021 Apr 15.

Department of Urology, the First Affiliated Hospital of Nanchang University, Nanchang, China.

Objectives: To assess the perioperative, functional, and oncological outcomes of transvesical robot-assisted radical prostatectomy (T-RARP) and posterior robot-assisted radical prostatectomy (P-RARP) for localized prostate cancer.

Materials And Methods: We analyzed the data of 96 patients who underwent T-RARP or P-RARP for localized prostate cancer between January 2017 and June 2019 in a retrospective fashion.

Results: No significant differences in the baseline characteristics existed between the T-RARP and P-RARP arms. Read More

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The Effect of Action Research on Neobladder Function Training in Patients with Orthotopic Ileal Neobladders: A Prospective Cohort Study.

Urol J 2021 Apr 28. Epub 2021 Apr 28.

Department of Urinary Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China.

Purpose: This study aims to evaluate the effects of action research on neobladder function training in patients with orthotopic ileal neobladders.

Methods: A total of 68 patients with orthotopic ileal neobladders were randomly divided into two groups: a control group (31 patients) and an experimental group (37 patients). Patients in the control group received neobladder function training, while patients in the experimental group received neobladder function training based on the action research method. Read More

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Effect of a mobile digital intervention to enhance physical activity in individuals with metabolic disorders on voiding patterns measured by 24-h voided volume monitoring system: Kumejima Digital Health Project (KDHP).

Int Urol Nephrol 2021 Aug 28;53(8):1497-1505. Epub 2021 Apr 28.

Department of Molecular and Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.

Purpose: To evaluate the effect of a mobile digital intervention on voiding patterns, we performed 24-h voided volume monitoring in individuals with metabolic disorders.

Methods: Participants with metabolic disorders were grouped into either the intervention group (n = 17), who had access to a smartphone app (CARADA), or the non-intervention group (n = 11), who did not. Urine monitoring was conducted for 24 h using a novel digital self-health monitoring system for urine excretion (s-HMSU). Read More

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Prospective study of urinary function and analysis of risk factors after rectal cancer surgery.

Tech Coloproctol 2021 06 2;25(6):727-737. Epub 2021 Apr 2.

Department of General and Digestive Surgery, Colorectal Unit, Arnau de Vilanova Hospital, C/San Clemente no. 12, 46015, Valencia, Spain.

Background: Alterations in urinary function are complications of rectal cancer surgery. The aim of this study was to prospectively analyze the changes in urinary function in patients operated on for rectal cancer, and to identify risk factors that may have an impact on the deterioration of postoperative urinary function.

Methods: A prospective study of urinary function in rectal cancer patients who had elective oncological resection with curative intention at the Arnau de Vilanova Hospital in Valencia, Spain, from January 2017 to March 2019. Read More

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Epilobium angustifolium L. extract with high content in oenothein B on benign prostatic hyperplasia: A monocentric, randomized, double-blind, placebo-controlled clinical trial.

Biomed Pharmacother 2021 Jun 23;138:111414. Epub 2021 Mar 23.

Department of Pharmacy, University of Naples Federico II, via Domenico Montesano 49, 80131 Naples, Italy; International Research Center for Food Nutrition and Safety, Jiangsu University, 212013 Zhenjiang, China. Electronic address:

Benign prostatic hyperplasia (BPH) is a common condition in adult men. Especially in Europe, increasing attention has been focused on E. angustifolium extracts (EAEs), which are widely used for their positive effects on the symptoms of BPH, although human clinical trials are limited. Read More

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Impact of bariatric surgery in patients with stress urinary incontinence.

Einstein (Sao Paulo) 2021 15;19:eAO5701. Epub 2021 Mar 15.

Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.

Objective: To examine epidemiologic, anthropometric and clinical variables associated with stress urinary incontinence in obese women, before and after bariatric surgery, and to identify predictive factors of stress urinary incontinence resolution.

Methods: Prospective observational study with women enrolled in a bariatric surgery program between 2015 and 2016. Patients were assessed prior to and 6 months after bariatric surgery using the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form, the Patient Global Impression of Improvement and the Visual Analogue Scale. Read More

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Effects of unsupervised behavioral and pelvic floor muscle training programs on nocturia, urinary urgency, and urinary frequency in postmenopausal women: Secondary analysis of a randomized, two-arm, parallel design, superiority trial (TULIP study).

Maturitas 2021 Apr 4;146:42-48. Epub 2021 Feb 4.

Helen W. & Thomas L. Umphlet Distinguished Professor in Aging, University of North Carolina at Chapel Hill, School of Nursing, CB 7460, Chapel Hill, NC 27599-7460, United States. Electronic address:

Objective: To determine and compare the effects of an unsupervised behavioral and pelvic floor muscle training (B-PFMT) program delivered in two formats on nocturia, urinary urgency, and urinary frequency in postmenopausal women.

Study Design: A secondary analysis used data collected from women enrolled in the TULIP study. Women aged 55 years or more with no urinary incontinence were provided the B-PFMT program. Read More

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Perineal urethrostomy with combined buccal mucosal graft and skin flap after complete loss of anterior urethra.

IJU Case Rep 2021 Mar 3;4(2):92-94. Epub 2021 Jan 3.

Department of Urology Hyogo College of Medicine Nishinomiya Hyogo Japan.

Introduction: We report a novel perineal urethrostomy procedure for complete loss of anterior urethral tissue.

Case Presentation: A 74-year-old man had complete necrosis of the corpus spongiosum and corpora cavernosa after repeated transurethral surgical procedures. He had been managed with a suprapubic cystostomy tube for 10 years. Read More

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Self-Management for Men With Lower Urinary Tract Symptoms: A Systematic Review and Meta-Analysis.

Ann Fam Med 2021 Mar-Apr;19(2):157-167

Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Queensland, Australia.

Purpose: Lower urinary tract symptoms are very common in older men. We conducted a systematic review and meta-analysis to evaluate the effects of self-management interventions on these symptoms.

Methods: We included randomized controlled trials comparing the effect of self-management interventions (alone or combined with drug therapy) with usual care or drug therapy alone in men with lower urinary tract symptoms. Read More

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February 2020

Lower urinary tract symptoms in female prison inmates: prevalence and impact on quality of life.

Int Urogynecol J 2021 Feb 20. Epub 2021 Feb 20.

Woman's Health Department, Federal University of Ceará, Fortaleza, Brazil.

Introduction And Hypothesis: The objective was to estimate the prevalence and assess the impact of lower urinary tract symptoms (LUTS) on the quality of life of incarcerated women.

Methods: Cross-sectional study conducted with 307 incarcerated women from the state of Ceará, Brazil, from June to September 2018. To identify the prevalence of symptoms, an instrument was developed according to the recommendations of the International Continence Society. Read More

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February 2021

Lower urinary tract symptoms in adolescent girls: a questionnaire-based study.

Eur J Obstet Gynecol Reprod Biol 2021 Mar 16;258:452-456. Epub 2021 Jan 16.

Clinic for Gynaecology and Perinatology, University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia.

Objective: To determine the prevalence of lower urinary tract symptoms (LUTS) in female adolescent population.

Study Design: We performed a questionnaire-based study in nine randomly selected high schools in our country. Our primary aim was to evaluate the prevalence of certain LUTS in adolescent girls: frequency, urgency, nocturia, feeling of incomplete bladder emptying, dysuria, and urinary incontinence. Read More

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The Sustained Therapeutic Effects of Percutaneous Posterior Tibial Nerve Stimulation in the Treatment of Neurogenic Lower Urinary Tract Symptoms in Patients with Parkinson's Disease: 24-months Clinical and Urodynamic Results.

Urology 2021 Jul 6;153:49-55. Epub 2021 Feb 6.

Kutahya Health Sciences University, Faculty of Medicine, Department of Neurology Kutahya, Turkey.

Objective: To determine the sustained therapeutic effect of percutaneous posterior tibial nerve stimulation (PTNS) treatment in Parkinson's disease patients with detrusor activity during 24 months.

Methods: After 12 weeks therapy, PTNS was applied at 14-day intervals for 3 months, 21-day intervals for 3 months and 28-day intervals through 24 months. The patients completed a 3-day voiding diary and ICIQ-SF, OAB-V8, OAB-q SF questionnaires at 3, 6, 9,12 and 24 month. Read More

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A low cost artisan tension-free tape technique cures pelvic organ prolapse and stress urinary incontinence - proof of concept.

Cent European J Urol 2020 3;73(4):490-497. Epub 2020 Dec 3.

Faculty of Medicine at LMU Munich, Munich, Germany.

Introduction: The primary cause of pelvic organ prolapse (POP) is weak cardinal/uterosacral (CL/USL) ligaments and for stress urinary incontinence, weak pubourethral ligaments (PUL).

Material And Methods: A 1 cm wide tape cut from a mesh sheet was applied tension-free to reinforce already plicated CL/USLs for cure of prolapse and directly to PUL for cure of stress urinary incontinence (SUI). 40 tapes were inserted, 10 midurethrally for SUI and 30 for 2/3 degree prolapse: 15 to uterosacral ligaments and 15 to cardinal ligaments. Read More

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December 2020

Ternary cancer comprising prostatic cancer, esophageal cancer, and gastric cardia cancer: a case report and literature review.

Int J Clin Exp Pathol 2020 1;13(12):3181-3186. Epub 2020 Dec 1.

Department of Oncology, The Third Affiliated Hospital of Soochow University 185 Juqian Street, Changzhou, Jiangsu Province, P. R. China.

A 61-year-old male patient was admitted to our hospital with frequent urination, urgency, and increased nocturia for more than 3 months, and the symptoms were aggravated for 1 week. Prostate biopsy revealed prostatic adenocarcinoma. After 5 months, the patient developed dysphagia and gastroscopy showed a middle and lower esophageal cancer (squamous cell carcinoma). Read More

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December 2020

Case Report: Ipilimumab-Induced Panhypophysitis: An Infrequent Occurrence and Literature Review.

Front Oncol 2020 1;10:582394. Epub 2020 Dec 1.

Department of Systems Medicine, Medical Oncology, University of Rome Tor Vergata, Rome, Italy.

Background: Immune checkpoint inhibitors (ICIs), by unleashing the anticancer response of the immune system, can improve survival of patients affected by several malignancies, but may trigger a broad spectrum of adverse events, including autoimmune hypophysitis. ICI-related hypophysitis mainly manifests with anterior hypopituitarism, while the simultaneous involvement of both anterior and posterior pituitary (i.e. Read More

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December 2020

Prevalence of nocturia after brain injury: a cross-sectional study in a single rehabilitation center.

Brain Inj 2021 01 14;35(1):90-95. Epub 2020 Dec 14.

Unità Spinale-Neuroriabilitazione, Medicina Riabilitativa, AUSL Piacenza, Piacenza, Italy.

: to analyze the prevalence of nocturia and its possible neuro-urological correlations in patients with a history of acquired brain injury (ABI).: a single-centre population-based prospective study involving outpatients who were previously admitted to our Rehabilitation Hospital for acute ABI ≥ 18 months and ≤2 years prior. Impact of nocturia on QoL was evaluated by the standardized International Consultation on Incotinence Nocturia Quality of Life (ICIQ N-QoL). Read More

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January 2021

Co-Occurrence of Systemic Lupus Erythematosus and Autoimmune Polyendocrine Syndrome II: Is There a Pathologic Link?

Cureus 2020 Oct 26;12(10):e11187. Epub 2020 Oct 26.

Medicine, Nazareth Hospital - Trinity Health Mid-Atlantic, Philadelphia, USA.

Autoimmune polyendocrine syndrome type II (APS II) is a rare endocrine disorder that involves the adrenal gland (Addison's disease), thyroid (autoimmune thyroiditis), pancreas (type 1 diabetes), and other non-endocrine organs. Herein, we report a case of a 58-year-old woman with a past medical history of systemic lupus erythematosus (SLE) and Addison's disease, who initially presented with nocturia, polyuria, abnormal sweating, fatigue, hair thinning, heat and cold intolerance, and progressive darkening of the skin for the last few months. After a thorough evaluation, she was diagnosed with autoimmune thyroiditis, and thus, she met the criteria for APS II. Read More

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October 2020

Night-Time Urinary Frequency Is Increased after the Great East Japan Earthquake along with Seasonal Variation: A Five-Year Longitudinal Study in Kesennuma City.

Tohoku J Exp Med 2020 12;252(4):329-337

Department of Urology, Tohoku University Graduate School of Medicine.

Disasters influence various health conditions; however, little has been reported about urinary symptoms. The objective of this study is to evaluate whether night-time urinary frequency was influenced by the Great East Japan Earthquake (GEJE) in March 2011. We also evaluated seasonal variation of night-time frequency, which may affect the primary objective. Read More

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December 2020

Improvement in Storage Related Lower Urinary Tract Symptoms following Urethroplasty: A Prospective Cohort Study.

J Urol 2021 Apr 20;205(4):1139-1144. Epub 2020 Nov 20.

Division of Urology, University of Alberta, Edmonton, Alberta, Canada.

Purpose: In patients with lower urinary tract symptoms, storage related symptoms induce the greatest degree of bother. When associated with urethral stricture, it is unclear how these specific symptoms respond to urethroplasty. This study aims to evaluate the prevalence and effect of urethroplasty on patient reported storage lower urinary tract symptoms. Read More

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Are falls in people with multiple sclerosis related to the severity of urinary disorders?

Ann Phys Rehabil Med 2021 Jul 5;64(4):101452. Epub 2020 Dec 5.

GRC 001, GREEN Groupe de recherche clinique en neuro-urologie, hôpital Tenon, Sorbonne Université, AP-HP, 75020 Paris, France.

Background: Lower urinary tract symptoms (LUTSs), especially overactive bladder, are frequent in people with multiple sclerosis (PwMS). Urinary urgency and urge urinary incontinence could lead to precipitation and thus could increase the risk of falling in these individuals.

Objective: We aimed to assess the association between severity of LUTSs and risk of falling in PwMS. Read More

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[Gender affirmation female to male-metaidoioplasty].

Urologe A 2020 Nov;59(11):1331-1339

Zentrum für Rekonstruktive Urogenitalchirurgie, Urologische Klinik München-Planegg, Germeringer Straße 32, 82152, Planegg, Deutschland.

Background: Description of an improved technique of metaidoioplasty (clitoris penoid) and presentation of the follow-up of our own patients in comparison to results in the literature.

Patients And Methods: To reduce the complication rate of urethral strictures and urethrocutaneous fistula, the technique of metaidoioplasty was modified: After elongation of clitoris by incision of chorda the urethra-including the clitoral hood-was reconstructed by distally, broadly based flap of labia minora. In a retrospective follow-up study over 4 years, 75 patients completed questionnaires to assess complications and satisfaction/quality of life and urinary symptoms (ICIQ-FLUTS questionnaire). Read More

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November 2020

Photodynamic Diagnosis-Assisted En Bloc Transurethral Resection of Bladder Tumor for Nonmuscle Invasive Bladder Cancer: Short-Term Oncologic and Functional Outcomes.

J Endourol 2021 03 3;35(3):319-327. Epub 2020 Nov 3.

Department of Urology, Nara Medical University, Kashihara, Japan.

We describe the oncologic and functional outcomes and the surgical technique of the photodynamic diagnosis (PDD)-assisted en bloc transurethral resection of bladder tumor (EBTUR) using a rectangular cutting loop. We reviewed 40 patients with carcinoma -free nonmuscle invasive bladder cancer undergoing PDD-TURBT. Of 40 patients, 12 underwent photodynamic diagnosis-assisted en bloc transurethral resection of bladder tumor (PDD-EBTUR) and 28 underwent PDD-assisted conventional TURBT (cTURBT). Read More

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