Curr Opin Support Palliat Care 2021 Mar 31. Epub 2021 Mar 31.
Signalling and Cancer Metabolism Team, Division of Cancer Biology, The Institute of Cancer Research Pain Medicine Department, The Royal Marsden Hospital Neurosciences Research Centre, Molecular and Clinical Sciences Institute, St George's, University of London Department of Neurosurgery, St George's University Hospital Targeted Approaches to Cancer Pain Group, The Institute of Cancer Research, London, UK.
Purpose Of Review: Advanced pain management techniques may be indicated in 5-15% of cancer patients. Despite this, a recent review identified that, over the course of 1 year in England, only 458 patients received a procedure intended to provide analgesia and only 30 patients had intrathecal drug delivery (ITDD) devices implanted. This article describes the emerging evidence for ITDD in cancer pain and provides a narrative review of other neuromodulatory techniques (including spinal cord stimulation, peripheral nerve stimulation and acupuncture), approaches that might be employed to address this area of significant unmet clinical need. Read More