572 results match your criteria modern inexpensive

Functional paper-based materials for diagnostics.

ChemTexts 2021 31;7(2):14. Epub 2021 Mar 31.

Merck Lab @ TU Darmstadt, Technische Universität Darmstadt, 64287 Darmstadt, Germany.

Functional papers are the subject of extensive research efforts and have already become an irreplaceable part of our modern society. Among other issues, they enable fast and inexpensive detection of a plethora of analytes and simplify laboratory work, for example in medical tests. This article focuses on the molecular and structural fundamentals of paper and the possibilities of functionalization, commercially available assays and their production, as well as on current and future challenges in research in this field. Read More

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Automated Applications of Acoustics for Stored Product Insect Detection, Monitoring, and Management.

Insects 2021 Mar 19;12(3). Epub 2021 Mar 19.

Tropical Research and Education Center, Institute of Food and Agricultural Sciences, University of Florida, Homestead, FL 33031, USA.

Acoustic technology provides information difficult to obtain about stored insect behavior, physiology, abundance, and distribution. For example, acoustic detection of immature insects feeding hidden within grain is helpful for accurate monitoring because they can be more abundant than adults and be present in samples without adults. Modern engineering and acoustics have been incorporated into decision support systems for stored product insect management, but with somewhat limited use due to device costs and the skills needed to interpret the data collected. Read More

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Upper-Body Strength Endurance and Power Norms in Healthy Collegiate Dancers: A 10-year Prospective Study.

J Strength Cond Res 2021 Mar 31. Epub 2021 Mar 31.

Sports Medicine Assessment Research and Testing (SMART) Laboratory, George Mason University, Manassas, Virginia; and Department of Dance, George Mason University, Fairfax, Virginia.

Abstract: Coogan, SM, Hansen-Honeycutt, J, Fauntroy, V, and Ambegaonkar, JP. Upper-body strength endurance and power norms in healthy collegiate dancers: A 10-year prospective study. J Strength Cond Res XX(X): 000-000, 2021-Dance is physically demanding and requires dancers to have adequate upper body (UB), core, and lower-body fitness to perform successfully. Read More

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Insights into the interactions and dynamics of a DES formed by phenyl propionic acid and choline chloride.

Sci Rep 2021 Mar 18;11(1):6384. Epub 2021 Mar 18.

Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, Iran.

Deep eutectic solvents (DESs) have received much attention in modern green chemistry as inexpensive and easy to handle analogous ionic liquids. This work employed molecular dynamics techniques to investigate the structure and dynamics of a DES system composed of choline chloride and phenyl propionic acid as a hydrogen bond donor and acceptor, respectively. Dynamical parameters such as mean square displacement, liquid phase self-diffusion coefficient and viscosity are calculated at the pressure of 0. Read More

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Modern Kinetics and Mechanism of Protein Folding: A Retrospective.

William A Eaton

J Phys Chem B 2021 Mar 16. Epub 2021 Mar 16.

Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0520, United States.

Modern experimental kinetics of protein folding began in the early 1990s with the introduction of nanosecond laser pulses to trigger the folding reaction, providing an almost 10-fold improvement in time resolution over the stopped-flow method being employed at the time. These experiments marked the beginning of the "fast-folding" subfield that enabled investigation of the kinetics of formation of secondary structural elements and disordered loops for the first time, as well as the fastest folding proteins. When I started to work on this subject, a fast folding protein was one that folded in milliseconds. Read More

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Umbilical vein injection for management of retained placenta.

Cochrane Database Syst Rev 2021 03 11;3:CD001337. Epub 2021 Mar 11.

Department of Women's and Children's Health, The University of Liverpool, Liverpool, UK.

Background: Retained placenta is a common complication of pregnancy affecting 1% to 6% of all births. If a retained placenta is left untreated, spontaneous delivery of the placenta may occur, but there is a high risk of bleeding and infection. Manual removal of the placenta (MROP) in an operating theatre under anaesthetic is the usual treatment, but is invasive and may have complications. Read More

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Coupling azo dye degradation and biodiesel production by manganese-dependent peroxidase producing oleaginous yeasts isolated from wood-feeding termite gut symbionts.

Biotechnol Biofuels 2021 Mar 8;14(1):61. Epub 2021 Mar 8.

Biofuels Institute, School of the Environment and Safety Engineering, Jiangsu University, Xuefu Rd. 301, Zhenjiang, 212013, China.

Background: Textile industry represents one prevalent activity worldwide, generating large amounts of highly contaminated and rich in azo dyes wastewater, with severe effects on natural ecosystems and public health. However, an effective and environmentally friendly treatment method has not yet been implemented, while concurrently, the increasing demand of modern societies for adequate and sustainable energy supply still remains a global challenge. Under this scope, the purpose of the present study was to isolate promising species of yeasts inhabiting wood-feeding termite guts, for combined azo dyes and textile wastewater bioremediation, along with biodiesel production. Read More

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The Self-Assembly and Design of Polyfunctional Nanosystems.

Int J Mol Sci 2021 Feb 23;22(4). Epub 2021 Feb 23.

A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, 8 Arbuzov Street, Kazan 420088, Russia.

The current task of the molecular sciences is to create unique nanostructured materials with a given structure and with specific physicochemical properties on the basis of the existing wide range of molecules of natural and synthetic origin. A promising and inexpensive way to obtain nanostructured materials is the spontaneous self-assembly of molecular building blocks during random collisions in real dispersive systems in solution and at interfaces. This editorial aims to summarize the major points from the 11 scientific papers that contributed to the special issue "The Self-Assembly and Design of Polyfunctional Nanosystems", assessing the modern self-assembly potential and strategies for maintaining sustainable development of the nanoindustry. Read More

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February 2021

Expanding the Boundary of Biorefinery: Organonitrogen Chemicals from Biomass.

Acc Chem Res 2021 Apr 12;54(7):1711-1722. Epub 2021 Feb 12.

Department of Chemical and Biomolecular Engineering, National University of Singapore, 117585, Singapore.

ConspectusOrganonitrogen chemicals are essential in many aspects of modern life. Over 80% of the top 200 prescribed pharmaceutical products contain at least one nitrogen atom in the molecule, while all top 10 agrochemicals contain nitrogen, just to name a few. At present, the prevailing industrial processes for manufacturing organonitrogen chemicals start from nonrenewable fossil resources, but eventually we have to make these chemicals in a more sustainable manner. Read More

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Merging shuttle reactions and paired electrolysis for reversible vicinal dihalogenations.

Science 2021 01;371(6528):507-514

Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zürich, Zürich, Switzerland.

Vicinal dibromides and dichlorides are important commodity chemicals and indispensable synthetic intermediates in modern chemistry that are traditionally synthesized using hazardous elemental chlorine and bromine. Meanwhile, the environmental persistence of halogenated pollutants necessitates improved approaches to accelerate their remediation. Here, we introduce an electrochemically assisted shuttle (shuttle) paradigm for the facile and scalable interconversion of alkenes and vicinal dihalides, a class of reactions that can be used both to synthesize useful dihalogenated molecules from simple alkenes and to recycle waste material through -dihalogenation. Read More

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January 2021

Carbon Dots-Based Logic Gates.

Nanomaterials (Basel) 2021 Jan 17;11(1). Epub 2021 Jan 17.

Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.

Carbon dots (CDs)-based logic gates are smart nanoprobes that can respond to various analytes such as metal cations, anions, amino acids, pesticides, antioxidants, etc. Most of these logic gates are based on fluorescence techniques because they are inexpensive, give an instant response, and highly sensitive. Computations based on molecular logic can lead to advancement in modern science. Read More

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January 2021

HPLC and ToF‒SIMS Analyses of Tree Sap Mixed with Other Natural Lacquers.

Molecules 2021 Jan 15;26(2). Epub 2021 Jan 15.

Advanced Analysis Center, Korea Institute of Science and Technology, Seoul 02792, Korea.

Lacquer sap has been used by humans from antiquitywhen it was treated as a luxury item because of its desirable physical properties. In modern times, although access barriers are lower, lacquer is still considered to be rare and valuable. Thus, low quality, inexpensive Vietnamese and Myanmarese lacquers and cashew nutshell liquid are frequently added to the costly lacquer sap from Korea, China, and Japan. Read More

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January 2021

Use of Lactobacillus paracasei isolated from whey for silver nanocomposite synthesis: Antiradical and antimicrobial properties against selected pathogens.

J Dairy Sci 2021 Mar 15;104(3):2480-2498. Epub 2021 Jan 15.

Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4, 87-100 Toruń, Poland; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.

The present research emphasizes the use of safe, inexpensive, and available whey using Lactobacillus paracasei as a source in silver nanocomposite synthesis as an alternative bioactive agent for dairy and biomedical applications. Through the multiinstrumental approach used in this study based on spectroscopic and microscopic methods as well as spectrometric techniques, the characterization and evaluation of silver composites and their antimicrobial and antiradical properties were enabled. Synthesized silver nanocomposites have been found in form of nanocrystals, naturally coated by an organic surface with high antimicrobial and antiradical properties. Read More

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High cell density cultivation enables efficient and sustainable recombinant polyamine production in the microalga Chlamydomonas reinhardtii.

Bioresour Technol 2021 Mar 15;323:124542. Epub 2020 Dec 15.

Bielefeld University, Faculty of Biology, Center for Biotechnology (CeBiTec), Universitätsstrasse 27, 33615 Bielefeld, Germany. Electronic address:

Modern chemical industry calls for new resource-efficient and sustainable value chains for production of key base chemicals such as polyamines. The green microalga Chlamydomonas reinhardtii offers great potential as an innovative green-cell factory by combining fast and inexpensive, phototrophic growth with mature genetic engineering. Here, overexpression of recombinant lysine decarboxylases in C. Read More

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Integrating amino acid oxidase with photoresponsive probe: A fast quantitative readout platform of amino acid enantiomers.

Talanta 2021 Mar 18;224:121894. Epub 2020 Nov 18.

College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety Central South University, Changsha, 410083, Hunan, China. Electronic address:

Low-cost, high-throughput, broadly useful photoresponsive enantiomeric excess (ee) sensing of amino acids remains challenging to date. Herein, based on the selective oxidation reaction of amino acid oxidase (AAO) to amino acid enantiomers (D/L-AA) and the oxidation reaction of substrate (HO) with aromatic boronic ester, we put forward a photoresponsive strategy for the determination of D/L-AA at a certain concentration. In this scheme, the substrate HO produced by the enzyme-catalyzed reaction was determined by sensitive fluorescent and colorimetric response of ethyl-3-(3-(benzothiazol-2-yl)-5-methyl-2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)phenyl)-2-cyanoacrylate (HBT-PB) to reflect the enantiomeric content at a certain concentration. Read More

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Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems.

Micromachines (Basel) 2020 Dec 25;12(1). Epub 2020 Dec 25.

Department of Mechanical and Electrical Engineering, SF&AT, Massey University, Auckland 0632, New Zealand.

Microfluidic devices are used to transfer small quantities of liquid through micro-scale channels. Conventionally, these devices are fabricated using techniques such as soft-lithography, paper microfluidics, micromachining, injection moulding, etc. The advancement in modern additive manufacturing methods is making three dimensional printing (3DP) a promising platform for the fabrication of microfluidic devices. Read More

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December 2020

COVID-19 diagnostic laboratory strategies: modern technologies and development trends (review of literature).

Klin Lab Diagn 2020 Dec;65(12):757-766

Somov Research Institute of Epidemiology and Microbiology, Russian Ministry of Education and Science.

The COVID-19 pandemic, associated with the new coronavirus SARS-CoV-2, has caused a surge in incidence worldwide, as well as a severe crisis in global health and economy. Therefore, fast and accurate diagnosis of infection is key to timely treatment and elimination of the spread of the virus. Currently, the standard method for detecting coronavirus is reverse transcription polymerase chain reaction (RT-PCR). Read More

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December 2020

Biomass residues as twenty-first century bioenergy feedstock-a comparison of eight integrated assessment models.

Clim Change 2020 10;163(3):1569-1586. Epub 2019 Sep 10.

PBL Netherlands Environmental Assessment Agency, P.O. box 30314, 2500 GH The Hague, The Netherlands.

In the twenty-first century, modern bioenergy could become one of the largest sources of energy, partially replacing fossil fuels and contributing to climate change mitigation. Agricultural and forestry biomass residues form an inexpensive bioenergy feedstock with low greenhouse gas (GHG) emissions, if harvested sustainably. We analysed quantities of biomass residues supplied for energy and their sensitivities in harmonised bioenergy demand scenarios across eight integrated assessment models (IAMs) and compared them with literature-estimated residue availability. Read More

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September 2019

Polyester or epoxy: assessing embedding product efficacy in paleohistological methods.

PeerJ 2020 15;8:e10495. Epub 2020 Dec 15.

Department of Biomedical Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States of America.

Histological examination of bone microstructure provides insight into extant and extinct vertebrate physiology. Fossil specimens sampled for histological examination are typically first embedded in an inexpensive polyester resin and then cut into thin sections, mounted on slides, and polished for viewing. Modern undecalcified bone is chemically processed prior to embedding in plastic resin, sectioning, mounting, and polishing. Read More

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December 2020

Therapeutic effects of hysterosalpingography contrast media in infertile women: what do we know about the H2O in the H2Oil trial and why does it matter?

Hum Reprod 2021 Feb;36(3):529-535

Liggins Institute, University of Auckland, Auckland, New Zealand.

Recent interest in the use of oil-soluble contrast media (OSCM) for hysterosalpingography (HSG) and other tubal flushing procedures is largely the result of publication of the large, multicentre, randomized controlled H2Oil trial in the New England Journal of Medicine in 2017, addressing the long-held suspicion that pregnancy rates following HSG with OSCM are higher than if a water-soluble contrast media (WSCM) is used. However, the findings of this trial have been compromised by the WSCM selected for comparison with OSCM. The chosen WSCM belongs to a superceded class of ionic media, with an iodine concentration, osmolality and viscosity all lying at the extreme end of the range for water-soluble radiographic contrast. Read More

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February 2021

Pathways related to the anti-cancer effects of metabolites derived from Cerrado Biome native plants: An update and bioinformatics analysis on oral squamous cell carcinoma.

Protein Pept Lett 2020 Dec 9. Epub 2020 Dec 9.

Department of Dentistry, Universidade Estadual de Montes Claros, Minas Gerais,. Brazil.

Background: Oral cancer is a significant health problem worldwide. Oral squamous cell carcinoma (OSCC) is a malignant neoplasm of epithelial cells that mostly affects different anatomical sites in the head and neck and derives from the squamous epithelium or displays similar morphological characteristics. Generally, OSCC is often the end stage of several changes in the stratified squamous epithelium, which begin as epithelial dysplasia and progress by breaking the basement membrane and invading adjacent tissues. Read More

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December 2020

Superabsorbent crosslinked bacterial cellulose biomaterials for chronic wound dressings.

Carbohydr Polym 2021 Feb 19;253:117247. Epub 2020 Oct 19.

Department of Microbiology and Biotechnology, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology, Szczecin, Piastów 45, 70-311 Szczecin, Poland. Electronic address:

In this work, we present a novel ex situ modification of bacterial cellulose (BC) polymer, that significantly improves its ability to absorb water after drying. The method involves a single inexpensive and easy-to-perform process of BC crosslinking, using citric acid along with catalysts, such as disodium phosphate, sodium bicarbonate, ammonium bicarbonate or their mixtures. In particular, the mixture of disodium phosphate and sodium bicarbonate was the most promising, yielding significantly greater water capacity (over 5 times higher as compared to the unmodified BC) and slower water release (over 6 times as compared to the unmodified BC). Read More

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February 2021

Refinement and validation of infrared thermal imaging (IRT): a non-invasive technique to measure disease activity in a mouse model of rheumatoid arthritis.

Arthritis Res Ther 2020 11 30;22(1):281. Epub 2020 Nov 30.

Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada.

Background: The discovery and development of new medicines requires high-throughput screening of possible therapeutics in a specific model of the disease. Infrared thermal imaging (IRT) is a modern assessment method with extensive clinical and preclinical applications. Employing IRT in longitudinal preclinical setting to monitor arthritis onset, disease activity and therapeutic efficacies requires a standardized framework to provide reproducible quantitative data as a precondition for clinical studies. Read More

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November 2020

Fabrication and Characterization of Aluminum Nanoparticle-Reinforced Composites.

Polymers (Basel) 2020 Nov 24;12(12). Epub 2020 Nov 24.

Department of Convergence Systems Engineering, Dankook University, Youngin 448-701, Korea.

With the expanding use of polymers in modern our lives, there is an increasing need to manufacture advanced engineering polymeric parts in a systematic and inexpensive way. Herein, we developed an organic inorganic hybrid composite material with excellent mechanical properties by enhancing the dispersion and moldability of fillers. For this, we prepared and analyzed the physical properties of acrylonitrile butadiene styrene (ABS)/aluminum nanoparticle composites. Read More

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November 2020

Simplified formats of modern biosensors: 60 years of using immunochromatographic test systems in laboratory diagnostics.

Klin Lab Diagn 2020 Sep;65(10):611-618

Somov Research Institute of Epidemiology and Microbiology, Russian Ministry of Education and Science.

Immunochromatographic test systems known to foreign laboratory diagnostic experts as lateral flow immunoassay (LFIA) are simplified tape formats of modern biosensors. For 60 years, they have been widely used for the rapid detection of target molecules (ligands) in biosubstrates and the diagnosis of many diseases and conditions. The growing popularity of these test systems for providing medical care or diagnostics in developing countries, medical facilities, in emergency situations, as well as for individual home use by patients while monitoring their health are the main factors contributing to the continuous development and improvement of these methods, the emergence of a new generation of formats. Read More

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September 2020

Musculoskeletal microbiology: The utility of the microbiome in orthopedics.

J Orthop Res 2021 02 7;39(2):251-257. Epub 2020 Dec 7.

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York, USA.

The past 15 years have witnessed a renaissance in the study of the microbes that colonize the human body. The vast majority of the human microbiome resides within the gut. Alterations to the gut microbiome have been associated with the pathogenesis and progression of wide-ranging diseases throughout the body-including atherosclerosis, depression, and obesity. Read More

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February 2021

A light way for nuclear cell biologists.

J Biochem 2020 Nov 27. Epub 2020 Nov 27.

Centers for Biological Signalling Studies BIOSS and CIBSS, Albert Ludwigs University of Freiburg, Freiburg, Germany.

The nucleus is a very complex organelle present in eukaryotic cells. Having the crucial task to safeguard, organize and manage the genetic information, it must tightly control its molecular constituents, its shape and its internal architecture at any given time. Despite our vast knowledge of nuclear cell biology, much is yet to be unraveled. Read More

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November 2020

Fluoroscopy: An essential diagnostic modality in the age of high-resolution cross-sectional imaging.

World J Radiol 2020 Oct;12(10):213-230

Department of Radiology, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, United States.

The importance of fluoroscopy as an imaging modality has been minimized relative to other cross-sectional modalities, including high-resolution computed tomography (CT), magnetic resonance imaging (MRI) and ultrasound. Fluoroscopy examinations have decreased in clinical practice due to reduced appreciation of its usefulness, insufficient training of residents, fewer staff with adequate expertise, and poor reimbursements relative to other modalities. We revisit and build upon the prior literature and history of this decreased utilization. Read More

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October 2020

Recent developments in diagnostic tools and bioanalytical methods for analysis of snake venom: A critical review.

Anal Chim Acta 2020 Nov 11;1137:208-224. Epub 2020 Aug 11.

Department of Molecular Biology and Biotechnology, School of Sciences, Tezpur University, Tezpur, 784028, Assam, India. Electronic address:

Snakebite is a neglected medical emergency causing fatalities and long-term disabilities throughout the world, especially in tropical countries. The effectiveness of therapy against snakebite is reliant on the unambiguous identification of bitten species of snake followed by immediate administration of venom-specific monovalent antivenom. However, this is a challenging task and therefore, over the several years scientists are constantly trying to address this issue by developing species-specific snake venom diagnostic kits as an alternative to classical methods of snake identification in clinics. Read More

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November 2020

Metal-organic magnets with large coercivity and ordering temperatures up to 242°C.

Science 2020 10;370(6516):587-592

Université de Bordeaux, CNRS, Centre de Recherche Paul Pascal, UMR 5031, F-33600 Pessac, France.

Magnets derived from inorganic materials (e.g., oxides, rare-earth-based, and intermetallic compounds) are key components of modern technological applications. Read More

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October 2020