27,293 results match your criteria moderate alcohol


Associations of clinical, psychological, and socioeconomic characteristics with nicotine dependence in smokers.

Sci Rep 2021 Sep 17;11(1):18544. Epub 2021 Sep 17.

Respiratory Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Cigarette smoking is a risk factor of mortality and morbidity from various cancerous, respiratory, and myocardial diseases. Nicotine dependence is assessed based on the degree of physical dependence. We aimed to determine the clinical, socioeconomic and psychological factors associated with the smoking status and degree of nicotine dependence of smokers. Read More

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September 2021

Serum catalytic iron and progression of chronic kidney disease: findings from the ICKD study.

Nephrol Dial Transplant 2021 Sep 17. Epub 2021 Sep 17.

George Institute for Global Health India, New Delhi.

Background: The non-transferrin bound catalytic iron moiety catalyses production of toxic reactive oxygen species and is associated with adverse outcomes. We hypothesized that serum catalytic iron (SCI) is associated with progression of chronic kidney disease (CKD).

Methods: Baseline samples of the Indian Chronic Kidney Disease participants with at least one follow up visit were tested for total iron, iron binding capacity, transferrin saturation, SCI, ferritin and hepcidin. Read More

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September 2021

Observing the Working Alliance in Videoconferencing Psychotherapy for Alcohol Addiction: Reliability and Validity of the Working Alliance Inventory Short Revised Observer.

Front Psychol 2021 31;12:647814. Epub 2021 Aug 31.

Human Sciences Institute, Psychology Department, Center for Research, Intervention, and Evaluation for Alcohol and Drugs, Federal University of Juiz de Fora, Juiz de Fora, Brazil.

The coronavirus disease-2019 (COVID-19) pandemic has affected the mental health and alcohol consumption of individuals. Videoconferencing psychotherapy has become a fundamental mode of treatment for people with alcohol use disorders. However, there are still doubts about its effectiveness and the therapeutic relationship. Read More

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Role of dietary factors in the prevention and treatment for depression: an umbrella review of meta-analyses of prospective studies.

Transl Psychiatry 2021 Sep 16;11(1):478. Epub 2021 Sep 16.

Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.

The role of diet in depression is becoming increasingly acknowledged. This umbrella review aimed to summarize comprehensively the current evidence reporting the effects of dietary factors on the prevention and treatment of depression. PubMed, Embase, and the Cochrane Library were searched up to June 2021 to identify relevant meta-analyses of prospective studies. Read More

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September 2021

Mobile phone sensor-based detection of subjective cannabis intoxication in young adults: A feasibility study in real-world settings.

Drug Alcohol Depend 2021 Sep 4;228:108972. Epub 2021 Sep 4.

Information School, University of Washington, Seattle, USA.

Background: Given possible impairment in psychomotor functioning related to acute cannabis intoxication, we explored whether smartphone-based sensors (e.g., accelerometer) can detect self-reported episodes of acute cannabis intoxication (subjective "high" state) in the natural environment. Read More

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September 2021

An integrated dual process simulation model of alcohol use behaviours in individuals, with application to US population-level consumption, 1984-2012.

Addict Behav 2021 Aug 22;124:107094. Epub 2021 Aug 22.

Department of Automatic Control and Systems Engineering, University of Sheffield, Mappin Street, Sheffield S1 3DA, UK.

Introduction: The Theory of Planned Behaviour (TPB) describes how attitudes, norms and perceived behavioural control guide health behaviour, including alcohol consumption. Dual Process Theories (DPT) suggest that alongside these reasoned pathways, behaviour is influenced by automatic processes that are determined by the frequency of engagement in the health behaviour in the past. We present a computational model integrating TPB and DPT to determine drinking decisions for simulated individuals. Read More

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Associations between alcohol consumption and anxiety, depression, and health-related quality of life in colorectal cancer survivors.

J Cancer Surviv 2021 Sep 16. Epub 2021 Sep 16.

Center of Research on Psychological disorders and Somatic diseases, Tilburg University, PO Box 90153, 5000 LE, Tilburg, The Netherlands.

Purpose: Alcohol consumption is a major risk factor for colorectal cancer (CRC). It is currently poorly understood, however, how alcohol and different alcoholic beverage types are related to psychosocial outcomes in CRC survivors.

Methods: We used data of N = 910 CRC survivors from the pooled EnCoRe and PROCORE cohorts and harmonized them into five time points: at diagnosis and 3, 6, 12, and 24 months post-diagnosis. Read More

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September 2021

Intake of GG (LGG) fermented milk before drinking alcohol reduces acetaldehyde levels and duration of flushing in drinkers with wild-type and heterozygous mutant : a randomized, blinded crossover controlled trial.

Food Funct 2021 Sep 16. Epub 2021 Sep 16.

Institute of Nutrition, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom 73170, Thailand.

Alcohol consumption leads to acetaldehyde accumulation, especially in people with mutant aldehyde dehydrogenase 2 gene (). Novel strategies to promote acetaldehyde detoxification are required to prevent alcohol-related toxicity. Probiotic bacteria such as GG (LGG) were shown to have capacity to detoxify acetaldehyde. Read More

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September 2021

Anabolic androgenic steroids used as performance and image enhancing drugs in professional and amateur athletes: Toxicological and psychopathological findings.

Hum Psychopharmacol 2021 Sep 15:e2815. Epub 2021 Sep 15.

Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research, National Institutes of Health, Baltimore, Maryland, USA.

Objective: The use of anabolic androgenic steroids (AASs) as performance and image enhancing drugs (PIEDs), once restricted to professional athletes, now includes amateurs and regular gym visitors. AAS use is associated with psychopathology, yet this relationship is complex and not fully understood. We aimed to assess the presence of AASs and other misused substances in athletes' biological samples and link toxicological to psychopathological findings. Read More

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September 2021

The Role of Clinical Characteristics in Stratifying Sedation Risk: A Cohort Study.

Gastroenterology Res 2021 Aug 21;14(4):214-219. Epub 2021 Aug 21.

Internal Medicine, Brown University, Providence, RI, USA.

Background: Determination of sedation type during gastrointestinal procedures is generally based on risk assessment via the American Society of Anesthesiologists (ASA) classification system, but the reliance of anesthesia risk on clinical factors remains largely uninvestigated. We aim to determine the association between various clinical factors and choice of sedation type during gastrointestinal procedures.

Methods: This single-center, retrospective cohort study used electronic medical records to identify patients receiving colonoscopy or endoscopy at Rhode Island Hospital. Read More

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Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial.

BMJ 2021 06 30;374:n1448. Epub 2021 Jun 30.

Department of Neurology, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Objective: To determine whether dietary interventions that increase n-3 fatty acids with and without reduction in n-6 linoleic acid can alter circulating lipid mediators implicated in headache pathogenesis, and decrease headache in adults with migraine.

Design: Three arm, parallel group, randomized, modified double blind, controlled trial.

Setting: Ambulatory, academic medical center in the United States over 16 weeks. Read More

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Alcohol Withdrawal Syndrome: Outpatient Management.

Am Fam Physician 2021 Sep;104(3):253-262

Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.

Approximately one-half of patients with alcohol use disorder who abruptly stop or reduce their alcohol use will develop signs or symptoms of alcohol withdrawal syndrome. The syndrome is due to overactivity of the central and autonomic nervous systems, leading to tremors, insomnia, nausea and vomiting, hallucinations, anxiety, and agitation. If untreated or inadequately treated, withdrawal can progress to generalized tonic-clonic seizures, delirium tremens, and death. Read More

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September 2021

Cu2O-Catalyzed Conversion of Benzyl Alcohols Into Aromatic Nitriles via the Complete Cleavage of the C≡N Triple Bond in the Cyanide Anion.

Chem Asian J 2021 Sep 15. Epub 2021 Sep 15.

Henan Agricultural University, College of Science, Zhengzhou, CHINA.

Nitrogen transfer from cyanide anion to the aldehydes is emerging as a promising method for synthesis of aromatic nitriles. However this method still suffers from a disadvantage that a use of stoichiometric Cu(II) or Cu(I) salts is required to enable the reaction. In the present article, we overcame this drawback, and developed a catalytic method for the nitrogen transfer from cyanide anion to the alcohols via the complete cleavage of the C≡N triple bond using phen/Cu2O as the catalyst. Read More

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September 2021

Stressful life events and transitions in problematic alcohol use involvement among US adults.

Subst Use Misuse 2021 Sep 15:1-10. Epub 2021 Sep 15.

Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Objective: We investigated the impact of stressful life events (SLEs) for males and females on transitions in problematic alcohol involvement, both progression and recovery, over a 3-year interval.

Method: Participants of both Wave 1 (2001-2002) and Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) were stratified by sex (14,233 males and 19,550 females). Latent transition analysis estimated the impact of experiencing ≥3 SLE in the year preceding the Wave 1 interview on the probability of transitioning between three empirically-derived stages of alcohol involvement (patterns of alcohol use disorder [AUD] symptoms), across waves. Read More

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September 2021

Relationship between drinking frequency and fatty liver prevalence or incidence in Japanese undergoing health checkup in 2008-2019.

Liver Int 2021 Sep 15. Epub 2021 Sep 15.

Department of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Background & Aims: The relationship between the frequency of drinking and fatty liver in the general population is still poorly understood. This study analysed data from a large cohort who underwent health checkups in Japan between 2008 and 2019 to investigate the prevalence and incidence of fatty liver by alcohol consumption and risk factors for fatty liver.

Methods: The prevalence of fatty liver diagnosed with ultrasonography was calculated in 75,670 residents. Read More

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September 2021

Sex-specific effect of prenatal alcohol exposure on N-Methyl-D-Aspartate Receptor function in orbitofrontal cortex pyramidal neurons of mice.

Alcohol Clin Exp Res 2021 Sep 15. Epub 2021 Sep 15.

Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.

Background: Alcohol consumption during pregnancy can produce behavioral and cognitive deficits that persist into adulthood including impairments in executive functions, learning, planning and cognitive flexibility. We have previously shown that moderate prenatal alcohol exposure (PAE) significantly impairs reversal learning, a measure of flexibility mediated across species by different brain areas including the orbital frontal cortex (OFC). Reversal learning is likewise impaired by genetic or pharmacological inactivation of GluN2B subunit-containing N-Methyl-D-aspartate receptors (NMDARs). Read More

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September 2021

Intake of Nuts and Seeds Is Associated with a Lower Prevalence of Nonalcoholic Fatty Liver Disease in US Adults: Findings from 2005-2018 NHANES.

J Nutr 2021 Sep 15. Epub 2021 Sep 15.

Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia.

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease globally. Nuts and seeds, due to their unique nutrient composition, may provide health benefits for the prevention of NAFLD. To date, no research has investigated the association between nut and seed intake and NAFLD prevalence in a non-Mediterranean Western population. Read More

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September 2021

Prevalence of Human Papillomavirus (HPV) 16 and 18 in Oral Malignant and Potentially Malignant Disorders: A Polymerase Chain Reaction Analysis - A Comparative Study.

Ann Maxillofac Surg 2021 Jan-Jun;11(1):6-11. Epub 2021 Jul 24.

Department of Oral Pathology, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.

Introduction: Human papillomavirus (HPV) are now being increasingly associated as a cause of oral squamous cell carcinomas (OSCC). This study was designed to evaluate the prevalence of HPV in Pelizaeus-Merzbacher disease (PMD) and OSCC using polymerase chain reaction that might help in better understanding of the role played by this virus in the oncogenic process even from its evolution stage.

Materials And Methods: Formalin-fixed paraffin-embedded tissue samples ( = 40) of OSCC and mild, moderate, and severe dysplasia were used for this study. Read More

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Association of Psychological Resilience With Healthy Lifestyle and Body Weight in Young Adulthood.

J Adolesc Health 2021 Sep 11. Epub 2021 Sep 11.

Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, Massachusetts.

Purpose: Childhood adversity is associated with adverse health outcomes, in part owing to its effects on healthy lifestyle. We examined whether psychological resilience to adversity may promote healthier behaviors and body weight in young adulthood.

Methods: Data are from the Growing Up Today Study, a longitudinal cohort of young adults (n = 3,767) who are children of participants of the Nurses' Health Study II, a separate longitudinal cohort. Read More

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September 2021

A Meta-Analysis of Erectile Dysfunction and Alcohol Consumption.

Urol Int 2021 Sep 14:1-17. Epub 2021 Sep 14.

Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Purpose: The purpose of the study was to evaluate the association between alcohol consumption and risk of erectile dysfunction (ED).

Methods: PubMed was searched for reports published before June 2019. Data were extracted and combined odds ratios (ORs) calculated with random-effects models. Read More

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September 2021

Successful rotation from long-acting full agonist opioids to sublingual buprenorphine/naloxone using a microdosing approach.

J Opioid Manag 2021 ;17(7):159-166

Next Step Drug and Alcohol Services, Mental Health Commission, Western Australia, Perth, Australia.

Buprenorphine/naloxone (BPN/NX) is a first-line treatment for opioid use disorder. Conventional treatment guidelines recommend a period of opioid abstinence and the presence of moderate withdrawal before initiation to avoid precipitated withdrawal. A newer approach of "microdosing" removes this requirement and has potential benefits. Read More

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September 2021

Electronic cigarettes for smoking cessation.

Cochrane Database Syst Rev 2021 Sep 14;9:CD010216. Epub 2021 Sep 14.

Wolfson Institute of Preventive Medicine, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Background: Electronic cigarettes (ECs) are handheld electronic vaping devices which produce an aerosol formed by heating an e-liquid. Some people who smoke use ECs to stop or reduce smoking, but some organizations, advocacy groups and policymakers have discouraged this, citing lack of evidence of efficacy and safety. People who smoke, healthcare providers and regulators want to know if ECs can help people quit and if they are safe to use for this purpose. Read More

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September 2021

Minority Stress and Nicotine Use and Dependence among Sexual Minority Youth.

Subst Use Misuse 2021 Sep 14:1-5. Epub 2021 Sep 14.

Department of Health Studies, American University, Washington DC, USA.

Sexual minority youth (SMY), especially those who are plurisexual (e.g. bisexual, pansexual, queer), are more likely to use nicotine or develop nicotine dependence than their heterosexual peers, and this disparity is often attributed to minority stress (e. Read More

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September 2021

The effect of acute alcohol intoxication on alcohol cue salience: An event-related brain potential study.

Psychol Addict Behav 2021 Sep 13. Epub 2021 Sep 13.

Department of Psychology.

Objective: Alcohol cue salience is considered core to the broader understanding of drinking behaviors. In the present research, we sought to build the knowledge of alcohol cue salience by exploring P3 responses to alcohol images among social drinkers within a large-scale alcohol-administration study.

Method: Participants ( = 246) were randomly assigned to receive either a moderate dose of alcohol (target BAC = . Read More

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September 2021

Longitudinal Assessment of Alcohol Consumption throughout the First COVID-19 Lockdown: Contribution of Age and Pre-Pandemic Drinking Patterns.

Eur Addict Res 2021 Sep 3:1-8. Epub 2021 Sep 3.

Louvain Experimental Psychopathology Research Group (LEP), Psychological Sciences Research Institute, UCLouvain, Louvain-la-Neuve, Belgium.

Introduction: The COVID-19 outbreak and the related lockdown measures have raised concerns regarding mental health, including alcohol misuse. Preliminary studies investigated alcohol consumption at the early stages of lockdown, but no longitudinal data regarding its evolution during and after the first lockdown are currently available.

Methods: We investigated changes in alcohol consumption among a convenience sample of 1,693 French-speaking Belgian adults using a 3-stage longitudinal online survey. Read More

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September 2021

Technology-mediated just-in-time adaptive interventions (JITAIs) to reduce harmful substance use: A systematic review.

Addiction 2021 Sep 13. Epub 2021 Sep 13.

TSET Health Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, USA.

Background And Aims: Lapse risk when trying to stop or reduce harmful substance use is idiosyncratic, dynamic and multi-factorial. Just-in-time adaptive interventions (JITAIs) aim to deliver tailored support at moments of need or opportunity. We aimed to synthesise evidence on decision points, tailoring variables, intervention options, decision rules, study designs, user engagement and effectiveness of technology-mediated JITAIs for reducing harmful substance use. Read More

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September 2021

Epidemiology, Hot Spots, and Sociodemographic Risk Factors of Alcohol Consumption in Indian Men and Women: Analysis of National Family Health Survey-4 (2015-16), a Nationally Representative Cross-Sectional Study.

Front Public Health 2021 27;9:617311. Epub 2021 Aug 27.

Department of Epidemiology and Public Health, Central University of Tamil Nadu, Thiruvarur, India.

To map the alcohol hot spots and understand the Sociodemographic Indices (SDI) affecting alcohol consumption in Indian men and women. Data from National Family Health Survey-4 carried out from 2015 to 2016 with a sample size of 103,411 men and 699,686 women were used for Geographic Information System mapping, and hot spot identification by spatial statistics (Getis-Ord Gi). Bivariate analyses and multiple logistic regressions were used to analyze SDI. Read More

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September 2021

A randomized controlled trial of a therapeutic relational agent for reducing substance misuse during the COVID-19 pandemic.

Drug Alcohol Depend 2021 Aug 27;227:108986. Epub 2021 Aug 27.

Woebot Health, USA.

Background: The COVID-19 pandemic disrupted access to treatment for substance use disorders (SUDs), while alcohol and cannabis retail sales increased. During the pandemic, we tested a tailored digital health solution, Woebot-SUDs (W-SUDs), for reducing substance misuse.

Methods: In a randomized controlled trial, we compared W-SUDs for 8 weeks to a waitlist control. Read More

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Moderator effects in a randomized controlled trial of the Common Elements Treatment Approach (CETA) for intimate partner violence and hazardous alcohol use in Zambia.

Drug Alcohol Depend 2021 Aug 28;228:108995. Epub 2021 Aug 28.

Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Background: Intimate partner violence (IPV) and hazardous alcohol use are prevalent and co-occurring problems in low- and middle-income countries (LMICs). While limited evidence suggests that cognitive behavioral therapy (CBT) interventions can help address these problems, few randomized trials in LMICs have investigated moderators of treatment effectiveness. This study explores moderating factors impacting responsiveness to a CBT-based intervention for IPV and hazardous alcohol use among couples in Zambia. Read More

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Psychological distress, fear and coping among Malaysians during the COVID-19 pandemic.

PLoS One 2021 10;16(9):e0257304. Epub 2021 Sep 10.

School of Health, Federation University Australia, Berwick, Victoria, Australia.

Introduction: The COVID-19 pandemic has enormously affected the psychological well-being, social and working life of millions of people across the world. This study aimed to investigate the psychological distress, fear and coping strategies as a result of the COVID-19 pandemic and its associated factors among Malaysian residents.

Methods: Participants were invited to an online cross-sectional survey from Aug-Sep 2020. Read More

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September 2021