9,580 results match your criteria model seasonal


Seasonal variations in the diagnosis of the top 10 cancers in Korea: A nationwide population-based study using a common data model.

J Gastroenterol Hepatol 2021 Jul 22. Epub 2021 Jul 22.

Department of Internal Medicine, Division of Gastroenterology, Kyung Hee University School of Medicine, Seoul, Korea.

Background And Aim: A better understanding of seasonal variations in cancer diagnosis may be the first step toward optimal resource distribution in the National Cancer Screening Program (NCSP). This study aimed to identify seasonal variations in the diagnosis of the top 10 major cancers in Korea.

Study: We conducted a retrospective, observational cohort study in participants aged ≥ 20 years between 2012 and 2016 from the Health Insurance Review and Assessment-National Patient Sample database, previously converted to a common data model. Read More

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Associations of Seasonal Variations and Meteorological Parameters with Incidences of Upper and Lower Gastrointestinal Bleeding.

J Gastroenterol Hepatol 2021 Jul 21. Epub 2021 Jul 21.

School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.

Background: Previous studies have demonstrated the seasonal variations of non-variceal upper gastrointestinal bleeding (UGIB), but there is scanty data on lower gastrointestinal bleeding (LGIB) and the association with other meteorological parameters.

Methods: We included all patients hospitalized for UGIB and LGIB between 2009 and 2018 in Hong Kong. The monthly age- and sex-standardized GIB incidences were fitted to meteorological data including average temperature (AT), maximum temperature (MaxT), minimum temperature (MinT), temperature range (TR), average precipitation, average atmospheric pressure (AtomP) and average relative humidity after adjusting for prescriptions of aspirin, proton pump inhibitors and Helicobacter pylori eradication therapy using the autoregressive integrated moving average (ARIMA) model. Read More

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[Effects of environmental factors on the distribution of suitable habitats of in China].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2021 Jun;33(3):281-286

School of Public Health and Management, Weifang Medical University, China.

Objective: To identify the environmental factors affecting the distribution of suitable habitats of , and to examine the effects of environmental changes on the distribution of suitable habitats of .

Methods: Data pertaining to the distribution of in China were captured by literature review. The distribution of suitable habitats of in China was simulated using the maximum entropy model with the environmental variable data and the distribution data. Read More

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Modeling the selective advantage of new amino acids on the hemagglutinin of H1N1 influenza viruses using their patient age distributions.

Virus Evol 2021 Jan 28;7(1):veab049. Epub 2021 May 28.

Division of Bioinformatics, International Institute for Zoonosis Control, Hokkaido University, Sapporo 0010020, Japan.

In 2009, a new strain of H1N1 influenza A virus caused a pandemic, and its descendant strains are causing seasonal epidemics worldwide. Given the high mutation rate of influenza viruses, variant strains having different amino acids on hemagglutinin (HA) continuously emerge. To prepare vaccine strains for the next influenza seasons, it is an urgent task to predict which variants will be selected in the viral population. Read More

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January 2021

Solar UV-B/A radiation is highly effective in inactivating SARS-CoV-2.

Sci Rep 2021 07 20;11(1):14805. Epub 2021 Jul 20.

Department of Pathophysiology and Transplantation, University of Milano, Don C. Gnocchi Foundation, IRCCS, Milan, Italy.

Solar UV-C photons do not reach Earth's surface, but are known to be endowed with germicidal properties that are also effective on viruses. The effect of softer UV-B and UV-A photons, which copiously reach the Earth's surface, on viruses are instead little studied, particularly on single-stranded RNA viruses. Here we combine our measurements of the action spectrum of Covid-19 in response to UV light, Solar irradiation measurements on Earth during the SARS-CoV-2 pandemics, worldwide recorded Covid-19 mortality data and our "Solar-Pump" diffusive model of epidemics to show that (a) UV-B/A photons have a powerful virucidal effect on the single-stranded RNA virus Covid-19 and that (b) the Solar radiation that reaches temperate regions of the Earth at noon during summers, is sufficient to inactivate 63% of virions in open-space concentrations (1. Read More

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Kinetics of the SARS-CoV-2 antibody response and serological estimation of time since infection.

J Infect Dis 2021 Jul 19. Epub 2021 Jul 19.

Department of Immunology, St James's Hospital, Dublin, Ireland.

Background: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a complex antibody response that varies by orders of magnitude between individuals and over time.

Methods: We developed a multiplex serological test for measuring antibodies to five SARS-CoV-2 antigens and the Spike proteins of seasonal coronaviruses. We measured antibody responses in cohorts of hospitalized patients and healthcare workers followed for up to eleven months after symptoms. Read More

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Spatio-Temporal Analysis of Influenza-Like Illness and Prediction of Incidence in High-Risk Regions in the United States from 2011 to 2020.

Int J Environ Res Public Health 2021 Jul 2;18(13). Epub 2021 Jul 2.

Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.

About 8% of the Americans contract influenza during an average season according to the Centers for Disease Control and Prevention in the United States. It is necessary to strengthen the early warning for influenza and the prediction of public health. In this study, Spatial autocorrelation analysis and spatial scanning analysis were used to identify the spatiotemporal patterns of influenza-like illness (ILI) prevalence in the United States, during the 2011-2020 transmission seasons. Read More

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Diagnosis of respiratory disease in preweaned dairy calves using sequential thoracic ultrasonography and clinical respiratory scoring: Temporal transitions and association with growth rates.

J Dairy Sci 2021 Jul 15. Epub 2021 Jul 15.

Section of Herd Health and Animal Husbandry, School of Veterinary Medicine, University College Dublin, Belfield, Dublin, Ireland D04 W6F6.

Bovine respiratory disease (BRD) in dairy calves is a multifactorial condition, involving environmental, host, and pathogen factors. Thoracic ultrasound scoring (TUS) has recently been validated as an accurate method of detecting BRD-related lung pathology in dairy calves. Previous studies investigating the use of TUS in preweaned dairy calves have largely been based on cross-sectional data from all-year production systems. Read More

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Longitudinal assessment of kidney function in migrant farm workers.

Environ Res 2021 Jul 14;202:111686. Epub 2021 Jul 14.

Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Ave, PO 245210, Tucson, AZ, 85724, USA.

Chronic kidney disease of unknown etiology (CKDu) is an epidemic that affects young agricultural workers in several warm regions of the world. However, there is a lack of monitoring of kidney issues in regions with extremely warm environments such as the Northwest of Mexico, a semi-arid region with a growing agricultural industry, where migrant and seasonal farm workers (MSFWs) travel to work in the fields. The objective of this study was to longitudinally assess kidney functioning of MSFWs in relation to pesticide exposure, heat stress and dehydration in a large-scale farm in Mexico. Read More

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Spatiotemporal distributions of pan evaporation and the influencing factors in China from 1961 to 2017.

Environ Sci Pollut Res Int 2021 Jul 16. Epub 2021 Jul 16.

Key Laboratory of Regional Ecology and Environmental Change, School of Geography and Information Engineering, China University of Geosciences, Wuhan, China.

Pan evaporation (EVP) is an important element of the hydrological cycle and exhibits a close relationship with climate change. In this study, the generalized regression neural network (GRNN) model and extreme gradient boosting (Xgboost) model were applied to estimate the monthly EVP. The spatiotemporal distributions of EVP and influencing factors in China and eight subregions from 1961 to 2017 were analyzed. Read More

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Short Telomeres and a T-Cell Shortfall in COVID-19: The Aging Effect.

medRxiv 2021 Jul 10. Epub 2021 Jul 10.

The slow pace of global vaccination and the rapid emergence of SARS-CoV-2 variants suggest recurrent waves of COVID-19 in coming years. Therefore, understanding why deaths from COVID-19 are highly concentrated among older adults is essential for global health. Severe COVID-19 T-cell lymphopenia is more common among older adults, and it entails poor prognosis. Read More

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Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust.

medRxiv 2021 Jul 8. Epub 2021 Jul 8.

Background: We aimed to measure SARS-CoV-2 seroprevalence in a cohort of healthcare workers (HCWs) during the first UK wave of the COVID-19 pandemic, explore risk factors associated with infection, and investigate the impact of antibody titres on assay sensitivity.

Methods: HCWs at Sheffield Teaching Hospitals NHS Foundation Trust (STH) were prospectively enrolled and sampled at two time points. SARS-CoV-2 antibodies were tested using an in-house assay for IgG and IgA reactivity against Spike and Nucleoprotein (sensitivity 99·47%, specificity 99·56%). Read More

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Influence of Seasonal Vitamin D Changes on Clinical Manifestations of Rheumatoid Arthritis and Systemic Sclerosis.

Front Immunol 2021 29;12:683665. Epub 2021 Jun 29.

Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine and Specialties (DIMI), University of Genova, IRCCS San Martino Polyclinic, Genova, Italy.

Vitamin D [1,25(OH)D-calcitriol] is basically a steroid hormone with pleiotropic biologic effects, and its impact on the regulation of immune system may influence several clinical conditions. Calcidiol (25OHD), as precursor of calcitriol, derives, for the most part (80%), from cutaneous cholesterol (7-dehydrocholesterol) under the action of UV-B (sunlight). Consequently, serum concentrations fluctuate during the year following the circannual rhythm of sun exposition. Read More

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Seasonal and diel activity patterns of the endangered taiga bean goose (Anser fabalis fabalis) during the breeding season, monitored with camera traps.

PLoS One 2021 15;16(7):e0254254. Epub 2021 Jul 15.

Department of Environmental and Biological Sciences, University of Eastern Finland, Joensuu, Finland.

Taiga bean goose (Anser fabalis fabalis) is an endangered subspecies that breeds sporadically in remote habitats in the arctic and boreal zones. Due to its elusive behaviour, there is a paucity of knowledge on the behaviour of taiga bean goose during the breeding season, and survey methods for monitoring numbers in the breeding areas are lacking. Camera traps are a useful tool for wildlife monitoring, particularly when there is a need for non-invasive methods due to the shy nature of the species. Read More

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Taphonomy of marine vertebrates of the Pisco Formation (Miocene, Peru): Insights into the origin of an outstanding Fossil-Lagerstätte.

PLoS One 2021 15;16(7):e0254395. Epub 2021 Jul 15.

Dipartimento di Scienze della Terra, Università di Pisa, Pisa, Italy.

The Miocene Pisco Formation, broadly exposed in the Ica Desert of southern Peru, is among the most outstanding Cenozoic marine Fossil-Lagerstätten worldwide. It is renowned for its exceptional preservation and abundance of vertebrate fossils, including a rich assemblage of whales and dolphins (Cetacea). Here, we integrate taphonomic data on 890 marine vertebrate fossils, gathered through 16 different localities. Read More

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Head Impact Biomechanics in Youth Flag Football: A Prospective Cohort Study.

Am J Sports Med 2021 Jul 15:3635465211026643. Epub 2021 Jul 15.

UGA Concussion Research Laboratory, Department of Kinesiology, University of Georgia, Athens, Georgia, USA.

Background: Youth flag football participation has rapidly grown and is a potentially safer alternative to tackle football. However, limited research has quantitatively assessed youth flag football head impact biomechanics.

Purpose: To describe head impact biomechanics outcomes in youth flag football and explore factors associated with head impact magnitudes. Read More

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Epidemiological and numerical simulation of rabies spreading from canines to various human populations in mainland China.

PLoS Negl Trop Dis 2021 Jul 14;15(7):e0009527. Epub 2021 Jul 14.

School of Optics and Photonics, Beijing Institute of Technology, Beijing, China.

Background: The mortality of humans due to rabies in China has been declining in recent years, but it is still a significant public health problem. According to the global framework, China strives to achieve the goal of eliminating human rabies before 2030.

Methods: We reviewed the epidemiology of human deaths from rabies in mainland China from 2004 to 2018. Read More

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Simple Framework to Quantify the Contributions from Different Factors Influencing Aerosol pH Based on NH Phase-Partitioning Equilibrium.

Environ Sci Technol 2021 Jul 14. Epub 2021 Jul 14.

Department of Chemistry, University of Toronto, Toronto M5S 3H6, Ontario, Canada.

While aerosol pH is among the most important parameters in atmospheric chemistry, it can be challenging to have a priori knowledge of the factors that are most strongly influencing the pH in a specific environment. In this study, we present a calculation method to more intuitively quantify the relationship between aerosol pH and its influencing factors, including gaseous NH concentration, particle properties, relative humidity, temperature, and nonvolatile cations, based on the NH phase-partitioning equilibrium used in the E-AIM thermodynamic model. The applications of this calculation framework include (1) expressing the pH values directly as the function of influencing factors, (2) quantitatively studying the contribution of different factors to pH value changes, and (3) decomposing the standard deviation of pH values to find the dominant influencing factors on total pH fluctuations. Read More

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Edaphoclimatic seasonal trends and variations of the spp. infection in Northwestern Mexico.

Infect Dis Model 2021 10;6:805-819. Epub 2021 Jun 10.

Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, México City, 04510, Mexico.

Currently, spp. is the bacterium causing the highest number of food-borne diseases (FADs) in the world. It is primarily associated with contaminated water used to that irrigates crops from intensive livestock farming. Read More

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Predicting seasonal influenza using supermarket retail records.

PLoS Comput Biol 2021 Jul 12;17(7):e1009087. Epub 2021 Jul 12.

Northeastern University, Boston, Massachusetts, United States of America.

Increased availability of epidemiological data, novel digital data streams, and the rise of powerful machine learning approaches have generated a surge of research activity on real-time epidemic forecast systems. In this paper, we propose the use of a novel data source, namely retail market data to improve seasonal influenza forecasting. Specifically, we consider supermarket retail data as a proxy signal for influenza, through the identification of sentinel baskets, i. Read More

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Seasonal variation of serum 25-hydroxyvitamin D level in hemodialysis patients in the northernmost island of Japan.

Clin Exp Nephrol 2021 Jul 12. Epub 2021 Jul 12.

Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, 060-8543, Japan.

Background: Serum vitamin D level shows a seasonal variation, being lower in winter than in summer in healthy subjects. The aim of this study was to determine whether there is presence of such a seasonal variation in hemodialysis patients.

Methods: A total of 102 patients on hemodialysis were enrolled in February 2017 (winter) for analyses of serum levels of 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)D] and treatments for chronic kidney disease-mineral and bone disorder (CKD-MBD). Read More

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Moving ecological and biogeochemical transitions across the North Pacific.

Limnol Oceanogr 2021 Jun 5;66(6):2442-2454. Epub 2021 May 5.

Department of Earth, Atmospheric and Planetary Sciences Massachusetts Institute of Technology Cambridge Massachusetts USA.

In the North Pacific Ocean, nutrient rich surface waters flow south from the subpolar gyre through a transitional region and into the subtropics. Along the way, nutrients are used, recycled, and exported, leading to lower biomass and a commensurate change in ecosystem structure moving southward. We focus on the region between the two gyres (the Transition Zone) using a coupled biophysical ocean model, remote sensing, floats, and cruise data to explore the nature of the physical, biogeochemical, and ecological fields in this region. Read More

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Future snow projections in a small basin of the Western Himalaya.

Sci Total Environ 2021 Jun 24;795:148587. Epub 2021 Jun 24.

HydroSciences Laboratory (CNRS, IRD, University of Montpellier), Montpellier, France.

Snow is a crucial component of the hydrological cycle in the Western Himalaya. Water from snowmelt is used in various sectors in downstream regions, thus playing a critical role in securing the livelihoods of millions of people. In this study, we investigated the future evolution of snow cover and snowmelt in the Panjshir catchment of Afghanistan, a sub-basin of the Indus, in the Western Himalaya. Read More

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Substantial shifts in flowering phenology of Sternbergia vernalis in the Himalaya: Supplementing decadal field records with historical and experimental evidences.

Sci Total Environ 2021 Jul 1;795:148811. Epub 2021 Jul 1.

Centre for Biodiversity & Taxonomy, Department of Botany, University of Kashmir, Srinagar 190 006, J&K, India. Electronic address:

In an age of anthropocene, shifting plant phenology is one of the most striking biological indicators of global environmental change. Majority of the studies reporting shifts in plant phenology are available from the North America and Europe and largely scarce from the developing world, including the Himalaya; and studies integrating multiple methodological approaches to investigate the climate-driven phenological shifts are too rare. Here, we report the shifts in spring flowering phenology of model plant species, Sternbergia vernalis in response to the changing climate in Kashmir Himalaya, by integrating decadal field observational records with long-term herbarium and dated-photograph data, and supported with experimental evidences. Read More

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Long-term behavior of PFAS in contaminated agricultural soils in Germany.

J Contam Hydrol 2021 Apr 17;241:103812. Epub 2021 Apr 17.

Center for Applied Geoscience, University of Tübingen, Schnarrenbergstraße 94-96, 72076 Tübingen, Germany.

PFAS contaminated compost material has been applied over the last few decades to agricultural fields in Germany, resulting in large-scale diffuse PFAS plumes. The leaching behavior of PFAS from the first two identified contaminated agricultural sites in Germany were investigated, one at Brilon-Scharfenberg, North Rhine-Westphalia Site (BS-NRW), and the other at Rastatt/Mannheim, Baden-Württemberg. The specific objectives of this study were to assess the longevity of the PFAS agricultural sources and compare standardized column percolation tests to long-term leaching of PFAS from contaminated sites. Read More

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Modeling heat stress effects on dairy cattle milk production in a tropical environment using test-day records and random regression models.

Animal 2021 Jul 7;15(8):100222. Epub 2021 Jul 7.

Institute of Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany. Electronic address:

In tropical environments, dairy cattle production is constrained by several factors, including climate. The seasonal loss of milk due to heat stress is a recurring challenge for many dairy producers. The objective of this study was to detect heat stress thresholds, milk yield loss and individual animal variations using random regression models for dairy cattle from test-day milk records. Read More

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Projections of temperature-attributable mortality in Europe: a time series analysis of 147 contiguous regions in 16 countries.

Lancet Planet Health 2021 Jul;5(7):e446-e454

ISGlobal, Barcelona, Spain.

Background: Europe has emerged as a major climate change hotspot, both in terms of an increase in seasonal averages and climate extremes. Projections of temperature-attributable mortality, however, have not been comprehensively reported for an extensive part of the continent. Therefore, we aim to estimate the future effect of climate change on temperature-attributable mortality across Europe. Read More

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Reducing influenza virus transmission: the value of antiviral treatment.

Clin Infect Dis 2021 Jul 10. Epub 2021 Jul 10.

University of Michigan School of Public Health, Ann Arbor, Michigan, USA.

Prompt antiviral treatment has the potential to reduce influenza virus transmission to close contacts, but rigorous data on the magnitude of treatment effects on transmission are limited. Animal model data indicate that rapid reductions in viral replication following antiviral treatment reduce the risk of transmission. Observational and clinical trial data with oseltamivir and other neuraminidase inhibitors indicate that prompt treatment of household index patients appears to reduce the risk of illness in contacts, although the magnitude of the reported effects has varied widely across studies. Read More

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Seasonal environmental variability drives microdiversity within a coastal Synechococcus population.

Environ Microbiol 2021 Jul 9. Epub 2021 Jul 9.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA.

Marine microbes often show a high degree of physiological or ecological diversity below the species level. This microdiversity raises questions about the processes that drive diversification and permit coexistence of diverse yet closely-related marine microbes, especially given the theoretical efficiency of competitive exclusion. Here, we provide insight with an 8-year time series of diversity within Synechococcus, a widespread and important marine picophytoplankter. Read More

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Leveraging observed soil heterotrophic respiration fluxes as a novel constraint on global-scale models.

Glob Chang Biol 2021 Jul 9. Epub 2021 Jul 9.

Climate and Global Dynamics Laboratory, National Center for Atmospheric Research, Boulder, CO, USA.

Microbially explicit models may improve understanding and projections of carbon dynamics in response to future climate change, but their fidelity in simulating global-scale soil heterotrophic respiration (R ), a stringent test for soil biogeochemical models, has never been evaluated. We used statistical global R products, as well as 7821 daily site-scale R measurements, to evaluate the spatiotemporal performance of one first-order decay model (CASA-CNP) and two microbially explicit biogeochemical models (CORPSE and MIMICS) that were forced by two different input datasets. CORPSE and MIMICS did not provide any measurable performance improvement; instead, the models were highly sensitive to the input data used to drive them. Read More

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