Coron Artery Dis 2021 Apr 19. Epub 2021 Apr 19.
Department of Medicine, University of Tennessee, Memphis, Tennessee Department of Cardiology, Gulf Coast Medical center, Alabama University of Osteopathic Medicine, Panama City, Florida Department of Biology, University of Memphis, Memphis, Tennessee Department of Cardiology, University of Tennessee, Jackson, Tennessee Department of Medicine, MedStar Washington Hospital Center, Washington, DC Department of Medicine, Veterans Affairs (VA) New England Healthcare System, Boston University Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Background: Whether percutaneous coronary intervention (PCI) improves clinical outcomes in patients with chronic angina and stable coronary artery disease (CAD) has been a continuing area of investigation for more than two decades. The recently reported results of the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches, the largest prospective trial of optimal medical therapy (OMT) with or without myocardial revascularization, provides a unique opportunity to determine whether there is an incremental benefit of revascularization in stable CAD patients.
Methods: Scientific databases and websites were searched to find randomized clinical trials (RCTs). Read More