Epidemiology 2021 Mar 22. Epub 2021 Mar 22.
Division of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, USA; UCSD Moores Cancer Center, La Jolla, CA, USA Department of Family Medicine and Public Health, and Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, USA; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA Division of Environmental Health, School of Public Health, San Diego State University, San Diego, CA, USA;
Background: Polychlorinated biphenyls (PCBs), a diverse class of chemicals, are hypothesized mammary carcinogens. We examined plasma levels of 17 PCBs as individual congeners and as a mixture in association with breast cancer using a novel approach based on quantile g-computation.
Methods: This study included 845 White and 562 Black women who participated in the population-based, case-control Carolina Breast Cancer Study Phase I. Read More