117 results match your criteria mivs

Epitope Mapping of the Diphtheria Toxin and Development of an ELISA-Specific Diagnostic Assay.

Vaccines (Basel) 2021 Mar 26;9(4). Epub 2021 Mar 26.

Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (FIOCRUZ), National Institute of Science and Technology for Innovation in Neglected Diseases Populations (INCT-IDNP), Rio de Janeiro 21040-900, Brazil.

The diphtheria toxoid antigen is a major component in pediatric and booster combination vaccines and is known to raise a protective humoral immune response upon vaccination. Although antibodies are considered critical for diphtheria protection, little is known about the antigenic determinants that maintain humoral immunity. One-hundred and twelve 15 mer peptides covering the entire sequence of diphtheria toxin (DTx) protein were prepared by SPOT synthesis. Read More

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A Novel End-To-End Feature Selection and Diagnosis Method for Rotating Machinery.

Sensors (Basel) 2021 Mar 15;21(6). Epub 2021 Mar 15.

School of Information and Control Engineering, China University of Mining and Technology, Xuzhou 221000, China.

Feature selection is to obtain effective features from data, also known as feature engineering. Traditional feature selection and predictive model learning are separated, and there is a problem of inconsistency of criteria. This paper presents an end-to-end feature selection and diagnosis method that organically unifies feature expression learning and machine prediction learning into one model. Read More

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Integrating metabolomic data with machine learning approach for discovery of Q-markers from Jinqi Jiangtang preparation against type 2 diabetes.

Chin Med 2021 Mar 19;16(1):30. Epub 2021 Mar 19.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China.

Background: Jinqi Jiangtang (JQJT) has been widely used in clinical practice to prevent and treat type 2 diabetes. However, little research has been done to identify and classify its quality markers (Q-markers) associated with anti-diabetes bioactivity. In this study, a strategy combining mass spectrometry-based untargeted metabolomics with backpropagation artificial neural network (BP-ANN)-based machine learning approach was proposed to screen Q-markers from JQJT preparation. Read More

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Heads-up 3D viewing system in rhegmatogenous retinal detachment with proliferative vitreoretinopathy - A prospective randomized trial.

Indian J Ophthalmol 2021 02;69(2):320-325

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To compare the outcomes of vitreoretinal surgery in patients with primary and recurrent rhegmatogenous retinal detachment (RRD) with proliferative vitreoretinopathy (PVR) on 3 dimensional digitally assisted visualization system (3D-DAVS) and conventional analogue microscope (CAM).

Methods: 68 patients with primary (50) and recurrent (18) RRD with PVR > C1 were included. One group underwent surgery on 3D-DAVS while the other on CAM. Read More

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February 2021

Factors impacting gas fill after microincision vitrectomy surgery combined with fluid-gas exchange.

Taiwan J Ophthalmol 2020 Oct-Dec;10(4):284-288. Epub 2020 Mar 31.

Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Purpose: The objective of the study was to investigate possible factors influencing gas fill after microincision vitrectomy surgery (MIVS) combined with fluid-gas exchange.

Materials And Methods: This was a retrospective chart review of patients who underwent MIVS combined with fluid-gas exchange (20% CF) from February 2017 to December 2017.

Results: Sixty-one eyes of 58 patients were identified. Read More

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Endophthalmitis after pars plana vitrectomy with reused single-use devices: a 13-year retrospective study.

Int J Retina Vitreous 2021 Jan 6;7(1). Epub 2021 Jan 6.

Department of Ophthalmology, Kresge Eye Institute, School of Medicine, Wayne State University, 4717 St. Antoine, Detroit, MI, 48201, USA.

Background: To describe the incidence, clinical characteristics, and treatment outcomes of endophthalmitis after pars plana vitrectomy (PPV) with recycled single-use devices. The recommended sterilization process as well as safety measures are discussed.

Methods: Medical charts of patients who developed endophthalmitis after PPV were retrospectively reviewed and reported in a descriptive manner. Read More

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January 2021

Micro-incision vitrectomy surgery for primary rhegmatogenous retinal detachments with posterior vitreous detachments in elderly patients: Preoperative characteristics and surgical outcomes.

PLoS One 2021 6;16(1):e0244614. Epub 2021 Jan 6.

Department of Ophthalmology, Keiyu Hospital, Yokohama, Japan.

Purpose: To assess the preoperative characteristics and surgical outcomes of using micro-incision vitrectomy surgery (MIVS) to treat RRD with posterior vitreous detachment (PVD) in an older and a younger patient group.

Methods: This retrospective cohort study included 407 eyes from 397 patients with primary RRD with PVD who were consecutively treated in our hospital from February 2016 to February 2020. PVD was diagnosed clinically by the presence of a Weiss ring, or was diagnosed morphologically via optical coherence tomography and subsequently confirmed during surgery. Read More

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25 vs. 27-gauge micro-incision vitrectomy surgery for visually significant macular membranes and full-thickness macular holes: a retrospective study.

Int J Retina Vitreous 2020 Nov 16;6(1):56. Epub 2020 Nov 16.

Oregon Eye Consultants LLC, 1550 Oak St, Suite 7, Eugene, OR, 97401, USA.

Background: To evaluate visual and safety outcomes for 25-gauge (25G) and 27-gauge (27G) micro-incision vitrectomy platforms (MIVS) for the treatment of epiretinal membrane and full-thickness macular holes.

Methods: Retrospective analysis of all patients who underwent internal limiting membrane (ILM) peel surgery from January 2017 through December 2018. 207 cases met the eligibility criteria for inclusion. Read More

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November 2020

Microincision vitrectomy surgery: experimental visualization and quantification of vitreous contamination.

BMC Ophthalmol 2020 Nov 10;20(1):441. Epub 2020 Nov 10.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo, 101-8309, Japan.

Background: To visualize and quantify vitreous contamination following microincision vitrectomy surgery (MIVS) using an experimental vitreous contamination model (EVCM).

Methods: Enucleated porcine eyes with fluoresbrite carboxylate microspheres applied to the conjunctival surface were used as a type 1 EVCM. Twenty-five- or 27-gauge (G) trocar cannulas were inserted through the conjunctiva and sclera, followed by the placing and opening of an infusion cannula. Read More

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November 2020

Dexamethasone/Netilmicin Eye Drops and Eye Gel for the Treatment of Ocular Inflammation After Micro-Incisional Vitreoretinal Surgery.

Clin Ophthalmol 2020 14;14:3297-3303. Epub 2020 Oct 14.

Medical Affairs, SIFI SpA, Catania, Italy.

Purpose: To evaluate the effect of dexamethasone/netilmicin (dexa/net) fixed combination in the treatment of ocular inflammation after sutureless micro-incisional vitreoretinal surgery (MIVS).

Patients And Methods: This multicenter, open, randomized, active-controlled, parallel-group, clinical trial was run in 6 sites in Italy. Treatment started the day of surgery and continued 4 times daily for 14 days. Read More

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October 2020

Psychological Effects of Skin Incision Size in Minimally Invasive Valve Surgery Patients.

Innovations (Phila) 2020 Nov/Dec;15(6):532-540. Epub 2020 Sep 28.

Cardiovascular Sciences Department, Agostino Gemelli Polyclinic Foundation IRCSS, Rome, Italy.

Objective: Clinical benefits of minimally invasive cardiac valve surgery (MIVS) have been reported. Improved postoperative mental status was never analyzed with dedicated psychological tests. In the present study we intend to investigate potential benefits of MIVS for patient psychological well-being, with special attention to the relevance of the patient perception of the chest surgical scar, of the self body image and cosmetic aspects. Read More

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September 2020

Comparison of 27-Gauge and 25-Gauge Microincision Vitrectomy Surgery for the Treatment of Vitreoretinal Disease: A Systematic Review and Meta-Analysis.

J Ophthalmol 2020 18;2020:6149692. Epub 2020 Aug 18.

Medical College of Qingha University, No. 16 of Konglun Road, Xining 810000, Qinghai Province, China.

Background: We performed a systematic review and meta-analysis to evaluate the safety and effectiveness of 27-gauge (27-G) microincision vitrectomy surgery (MIVS) compared with 25-guage (25-G) MIVS for the treatment of vitreoretinal disease.

Methods: A systematic electronic search was conducted in March 2020 in PubMed, Embase, and the Cochrane library. Eligible criteria for including studies were controlled trials comparing 27-G vitrectomy with 25-G vitrectomy in patients with vitreoretinal disease. Read More

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Pars plana vitrectomy in uveitis in the era of microincision vitreous surgery.

Indian J Ophthalmol 2020 Sep;68(9):1844-1851

Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Pars plana vitrectomy (PPV) in uveitis is indicated for various diagnostic and therapeutic indications. With the advent of microincision vitreous surgery (MIVS), the use of PPV in uveitis has increased with a wider spectrum of indications due to shorter surgical time, less patient discomfort, less conjunctival scarring, and a decreased rate of complications as compared to standard 20G vitrectomy. Because of faster post-operative recovery in terms of visual improvement and reduction of inflammation, and reduced duration of systemic corticosteroids, MIVS has gained popularity in uveitis as an adjunctive therapy to the standard of care medical therapy. Read More

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September 2020

p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers.

Biochem Biophys Res Commun 2020 08 17;529(3):582-589. Epub 2020 Jul 17.

Department of Surgical Oncology, Gifu University, Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.

Mitochondria-eating protein (Mieap) plays a critical role in mitochondrial quality control (MQC) and functions as a p53-inducible tumor suppressor. This study aimed to examine its role in gastric cancer (GC) and esophageal cancer (EC). GC cells were infected with Mieap-overexpressing adenovirus (Ad-Mieap) and subjected to fluorescence-activated cell sorting (FACS), western blotting, and caspase assays. Read More

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A Novel Multi-Scale Particle Morphology Descriptor with the Application of SPHERICAL Harmonics.

Materials (Basel) 2020 Jul 23;13(15). Epub 2020 Jul 23.

Department of Architecture and Civil Engineering, City University of Hong Kong, Hong Kong, China.

Particle morphology is of great significance to the grain- and macro-scale behaviors of granular soils. Most existing traditional morphology descriptors have three perennial limitations, i.e. Read More

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Successful surgical outcomes after 23-, 25- and 27-gauge vitrectomy without scleral encircling for giant retinal tear.

Jpn J Ophthalmol 2020 Sep 19;64(5):506-515. Epub 2020 Jul 19.

Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.

Purpose: Retinal detachment due to giant retinal tears (GRTs), tears larger than 90°, is rare and difficult to treat. Here, we show and compare surgical results of 23-, 25- and 27-gauge (G) micro-incision vitrectomy surgery (MIVS) for GRT.

Study Design: Retrospective and interventional case series. Read More

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September 2020

Association of retinal vessel density with retinal sensitivity in surgery for idiopathic epiretinal membrane.

Graefes Arch Clin Exp Ophthalmol 2020 Sep 3;258(9):1911-1920. Epub 2020 Jun 3.

Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba, Sendai, Miyagi, 980-8574, Japan.

Purpose: The success of surgical treatment for idiopathic epiretinal membrane (ERM) is measured by postoperative best-corrected visual acuity (BCVA), metamorphopsia, and foveal retinal sensitivity (RS).This study searched for predictive biomarkers of surgical success by determining the association between foveal RS and various aspects of vessel density (VD) in the fovea of patients with ERM.

Methods: The study examined 25 eyes of 25 patients with ERM who underwent 27-gauge microincision vitrectomy surgery (MIVS). Read More

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September 2020

Contemporary Outcomes and Prognostic Factors of 23-Gauge Vitrectomy for Retained Lens Fragments After Phacoemulsification.

Am J Ophthalmol 2020 11 29;219:271-283. Epub 2020 May 29.

Vitreoretinal Service, Moorfields Eye Hospital, London, United Kingdom. Electronic address:

Purpose: To provide data on visual acuity (VA) outcomes and prognostic factors of microincision (23-gauge) vitrectomy surgery (MIVS) for retained lens fragments after complicated cataract surgery.

Design: Retrospective, interventional case series from 2012 to 2017.

Methods: Precataract surgery and intraoperative (vitrectomy) parameters, postvitrectomy complications, and best-corrected visual acuities (BCVAs) were identified. Read More

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November 2020

Application of a Backpropagation Artificial Neural Network in Predicting Plasma Concentration and Pharmacokinetic Parameters of Oral Single-Dose Rosuvastatin in Healthy Subjects.

Clin Pharmacol Drug Dev 2020 10 26;9(7):867-875. Epub 2020 May 26.

Center of Clinical Pharmacology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China.

A backpropagation artificial neural network (BPANN) model was established for the prediction of the plasma concentration and pharmacokinetic parameters of rosuvastatin (RVST) in healthy subjects. The data (demographic characteristics and results of clinical laboratory tests) were collected from 4 bioequivalence studies using reference 10-mg RVST calcium tablets. After the data were cleaned using extreme gradient boosting, 13 important factors were extracted to construct the BPANN model. Read More

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October 2020

Microvesicles (MIVs) secreted from adipose-derived stem cells (ADSCs) contain multiple microRNAs and promote the migration and invasion of endothelial cells.

Genes Dis 2020 Jun 25;7(2):225-234. Epub 2019 Apr 25.

Department of Clinical Laboratory Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China.

Extracellular vesicles (EVs) such as microvesicles (MIVs) play an important role in intercellular communications. MIVs are small membrane vesicles sized 100-1000 nm in diameter that are released by many types of cells, such as mesenchymal stem cells (MSCs), tumor cells and adipose-derived stem cells (ADSC). As EVs can carry out autocrine and paracrine functions by controlling multiple cell processes, it is conceivable that EVs can be used as delivery vehicles for treating several clinical conditions, such as to improve cardiac angiogenesis after myocardial infarction (MI). Read More

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Hybrid 23/27 Gauge Vitrectomy - Combining the Charm of 27G with the Efficacy of 23G.

Clin Ophthalmol 2020 31;14:299-305. Epub 2020 Jan 31.

Swiss Eye Institute and Berner Augenklinik am Lindenhofspital, Bern, Switzerland.

Background: Minimally invasive transconjunctival sutureless vitrectomy (MIVS) has evolved into the standard of care, smaller incisions thought to result in lower ocular surface trauma and shorter times to recovery. The currently most relevant limitations in macular surgery may be light intensity and 27G instrument stability. Therefore, we thought to compare standard 23 and 27G vitrectomy with a hybrid technique using one 23G and two 27G ports regarding surgical times and short-term outcomes. Read More

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January 2020

Eckardt Forceps Tip Widening for the Removal of Posterior Intraocular Foreign Bodies Bigger Than 1 mm.

Retina 2020 Jan 22. Epub 2020 Jan 22.

Ophthalmology, Department of Surgery, Medicine, Molecular and Emergency, University of Pisa, Pisa, Italy.

Purpose: To propose a new technique with an "old" tool to allow for better intraocular foreign body (IOFB) grasping and manipulation during mininvasive vitreoretinal surgery.

Methods: The authors report herein their technique on seven eyes, diagnosed with posterior IOFBs, in which the surgery consisted of a 23-gauge vitrectomy, using, for IOFB grasping, a Grieshaber DSP 23-gauge Eckardt forceps, properly modified intraoperatively. Such result was achieved by enlarging the forceps opening bite, according to the IOFB size. Read More

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January 2020

Investigation on the Contributions of Different Muscles to the Generated Force based on HD-sEMG and DBN

Annu Int Conf IEEE Eng Med Biol Soc 2019 Jul;2019:2645-2648

In this study, we proposed a multi-muscle contraction force estimation framework and implemented it on the elbow flexion task to explore the contributions of different muscles to integrated force at different force levels. High density surface electromyography (HD-sEMG) signals were collected from four muscle groups and the wrist pulling force was measured synchronously. The deep belief network (DBN) was adopted to establish the relationship between HD-sEMG and force. Read More

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Comparative Study of Microbiological Profile and Management Outcomes of Acute Endophthalmitis after Microincision Vitrectomy Surgery versus Intravitreal Injections.

Ocul Immunol Inflamm 2020 Jan 3:1-7. Epub 2020 Jan 3.

Department of Vitreo-Retina, Aravind Eye Hospital, Madurai, India.

: The aim of this study was to evaluate and compare incidence and outcomes of management of acute endophthalmitis after microincision vitrectomy surgery (MIVS) and intravitreal injections (IVIs).: Medical records were retrospectively reviewed from January 2012 to December 2017, and the incidence, clinical and microbiological profiles of acute endophthalmitis were documented.: Of 26,332 MIVS and 24,143 IVI performed, incidence of acute endophthalmitis in MIVS group was 0. Read More

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January 2020

Outcome of primary rhegmatogenous retinal detachment using microincision vitrectomy and sutureless wide-angle viewing systems.

BMC Ophthalmol 2019 Nov 19;19(1):230. Epub 2019 Nov 19.

Department of Ophthalmology, China Medical University Hospital, China Medical University, 2 Yuh-Der Road, Taichung City, Taiwan, 40447.

Background: To evaluate the efficacy of micro-incision vitrectomy surgery (MIVS) using Lumera and Resight non-contact sutureless wide-angle viewing systems (WAVS) for primary rhegmatogenous retinal detachment (RRD), and to analyze the anatomical and visual outcomes.

Methods: The retrospective, non-comparative, interventional case series reported here was conducted from June 2014 through November 2016. Enrolled patients presented with primary RRD and received MIVS with/without cryopexy by one surgeon using the Lumera and Resight non-contact sutureless WAVS. Read More

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November 2019

Prognostic factors of revitrectomy for complications in eyes with proliferative diabetic retinopathy: a retrospective multicentre study.

Acta Ophthalmol 2020 Jun 1;98(4):e434-e439. Epub 2019 Nov 1.

Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan.

Purpose: To identify prognostic factors for revitrectomy in patients who underwent vitrectomy for complications with proliferative diabetic retinopathy (PDR) in multicentre study.

Methods: Consecutive 452 eyes of 452 patients with PDR undergoing 25-gauge microincision vitrectomy system (MIVS) in seven centres were retrospectivity reviewed. Preoperative ocular factors (baseline visual acuity [VA], vitreous haemorrhage [VH], tractional retinal detachment [TRD] and retinal photocoagulation), general factors (sex, age, diabetes duration, HbA1c level, hypertension, anti-coagulant medication and estimated glomerular filtration rate), surgical procedures (preoperative anti-vascular endothelial growth factor injection, internal limiting membrane peeling, combined cataract surgery, retinal break, and tamponade), postoperative complications for revitrectomy and postoperative VA at 6 months were evaluated. Read More

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Positive culture results and longer duration between onset and microincision vitrectomy have adverse effects on post-cataract surgery endophthalmitis outcome.

J Formos Med Assoc 2020 Jan 8;119(1 Pt 3):385-391. Epub 2019 Jul 8.

Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.

Purpose: To evaluate the efficacy of microincision vitrectomy surgery (MIVS) for the treatment of post-cataract surgery endophthalmitis, and to report the factors which influence the outcome.

Methods: This retrospective case series included eyes with post-cataract surgery endophthalmitis that had received MIVS between June 2014 and May 2017. The anatomical and functional results were analyzed. Read More

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January 2020

Surgical outcomes of microincision vitrectomy surgery in eyes with retinal detachment secondary to retinopathy of prematurity in Indian population.

Indian J Ophthalmol 2019 06;67(6):889-895

Department of Vitreoretinal Services, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To analyze and report outcomes of microincision vitrectomy surgery (MIVS) for Stage 4 and 5 retinopathy of prematurity (ROP).

Methods: Medical records of 202 eyes of 129 premature children undergoing MIVS for Stage 4/Stage 5 ROP between January 2012 and April 2015 were evaluated. The primary outcome measure was the proportion of eyes with anatomical success (defined as attached retina at the posterior pole at last follow-up). Read More

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Cardiac T2* magnetic resonance analysis of membranous interventricular septum in assessment of cardiac iron overload in pediatric thalassemia patients: A pilot study.

Indian J Radiol Imaging 2019 Jan-Mar;29(1):33-39

Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Background: Cardiac iron deposition in transfusion-dependent thalassemia patients is patchy in distribution.

Purpose: The purpose of this study is to assess the correlation between T2* matrices of membranous interventricular septum (MIVS) and T2* values of muscular interventricular septum (IVS) on magnetic resonance imaging (MRI) and to evaluate the relationship of myocardial T2* at these two locations with MRI-estimated liver iron concentrations (LIC) and electrocardiographic (ECG) parameters.

Material And Methods: MRI of heart and liver was performed in 16 consecutive pediatric patients of transfusion-dependent thalassemia major to calculate liver iron concentration and T2* time of membranous and muscular IVS. Read More

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Small gauge vitrectomy: operative techniques.

Curr Opin Ophthalmol 2019 May;30(3):159-164

Illinois Retina Associates, Rush University Medical Center, Chicago, IL USA.

Purpose Of Review: This article reviews operative techniques and risks associated with microincision vitrectomy surgery.

Recent Findings: All three microincision vitrectomy surgery platforms (23, 25, and 27 gauge) are associated with both advantages and disadvantages, combined with similarly low rates of hypotony, endophthalmitis, corneal astigmatism, and postoperative inflammation.

Summary: Hybrid-gauge vitrectomy, utilizing larger gauge MIVS cannulas, preserves surgeon access to benefits of both larger and smaller gauge MIVS platforms without compromising safety, efficacy, or efficiency. Read More

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