J Exp Bot 2019 11;70(21):6203-6214
Sorbonne Université, CNRS, IRD 242, INRA, PARIS 7, UPEC, Institut d'Ecologie et des Sciences de l'Environnement de Paris, iEES, Paris, France.
Leaf senescence is a form of developmentally programmed cell death that allows the remobilization of nutrients and cellular materials from leaves to sink tissues and organs. Among the catabolic reactions that occur upon senescence, little is known about the role of proline catabolism. In this study, the involvement in dark-induced senescence of proline dehydrogenases (ProDHs), which catalyse the first and rate-limiting step of proline oxidation in mitochondria, was investigated using prodh single- and double-mutants with the help of biochemical, proteomic, and metabolomic approaches. Read More