In Vitro Cell Dev Biol Anim 2020 Aug 4;56(7):522-532. Epub 2020 Aug 4.
Department of Dermatology, Xi'an Children's Hospital, 69 Xijuyuan Road, Lianhu District, Xi'an, 710000, China.
MicroRNAs (miRNAs) is involved in diverse biological processes of cells including dermal fibroblasts that contributed to wound healing and resulted in keloid scarring. MiR-506-3p has been identified as a tumor suppressor or oncogene in fibroblasts of various cancers, while the role of miR-506-3p in regulating functions of post-burn dermal fibroblasts is poorly known. In this study, miR-506-3p was confirmed to be significantly downregulated in burned tissues and heat-stimulated dermal fibroblasts. Read More