Pathol Res Pract 2021 Apr 5;220:153405. Epub 2021 Mar 5.
Departmentof Biochemistry and Molecular Biology, Bengbu Medical College, Anhui, 233030, China; Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Anhui, 233030, China. Electronic address:
MicroRNAs (miRNAs/miRs) are small, non-coding RNAs that are reported to serve numerous important regulatory functions; however, the role of miRNAs in regulating breast cancer cell biology remains poorly understood. Accumulating evidence has demonstrated that miRNAs orchestrate multiple cellular functions and serve crucial roles in cell differentiation and cancer development, either by acting as tumor suppressors or oncogenes. In particular, miR-155-5p expression levels have been found to be upregulated and serve as a prognostic marker in numerous types of solid cancer, including human breast cancer. Read More