286,042 results match your criteria middle-aged severe

Integrative effects of transcutaneous electrical acustimulation on abdominal pain, gastrointestinal motility, and inflammation in patients with early-stage acute pancreatitis.

Neurogastroenterol Motil 2021 Sep 18:e14249. Epub 2021 Sep 18.

Department of Gastroenterology, The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi, China.

Background/aims: Gastrointestinal (GI) dysmotility in acute pancreatitis (AP) aggravates inflammation and results in severe complications. This study aimed to explore effects and possible mechanisms of transcutaneous electrical acustimulation (TEA) on abdominal pain, GI dysmotility, and inflammation in AP patients.

Methods: Forty-two AP patients were blindly randomized to receive TEA (n = 21) at acupoints PC6 and ST36 or Sham-TEA (n = 21) at sham points for 2 days. Read More

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September 2021

The management of moderate acute malnutrition in children aged 6-59 mo in low- and middle-income countries: a systematic review and meta-analysis.

Trans R Soc Trop Med Hyg 2021 Sep 17. Epub 2021 Sep 17.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.

Background: Malnutrition is a leading cause of morbidity and mortality in children aged <5 y, especially in low- and middle-income countries (LMICs). Unlike severe acute malnutrition, moderate acute malnutrition (MAM) affects greater numbers globally, and guidelines lack a robust evidence base. This systematic review and meta-analysis assessed the evidence for lipid-based nutrient supplements (LNSs), fortified blended flours (FBFs) and nutrition counselling, in the treatment of MAM. Read More

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September 2021

Impact of genetic risk score on the association between male childlessness and cardiovascular disease and mortality.

Sci Rep 2021 Sep 17;11(1):18526. Epub 2021 Sep 17.

Reproductive Medicine Centre, Skåne University Hospital, Malmö, Sweden.

Childless men are reported to have a higher risk of cardiovascular disease (CVD) and mortality. Information on inherited genetic risk for CVD has improved the predictive models. Presuming that childlessness is a proxy of infertility we aimed to investigate if childless men inherit more often genetic traits for CVD and if combining genetic and parenthood information improves predictive models for CVD morbidity and mortality. Read More

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September 2021

Assessment of the emotional condition of women with cancer.

Eur Rev Med Pharmacol Sci 2021 Sep;25(17):5429-5435

Department of Clinical Nursing, Division of Oncology and Palliative Care, Faculty of Health Science, Wrocław Medical University, Wrocław, Poland.

Objective: The incidence of malignant tumors in women is constantly rising. In 2018, 83 876 women were diagnosed with cancer, and 46 028 died from it. Since the 1980s, the incidence of malignant tumors in women aged 19-44 has been growing dynamically, and in middle-aged women (between 45 and 64 years old), nearly one in two deaths are due to cancer - exceeding mortality from cardiovascular disease. Read More

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September 2021

A randomized placebo-controlled study: Phellodendron Bawei tablets combined with standard management can improve storage symptoms, sleep quality, and medication compliance in patients with benign prostatic hyperplasia compared to placebo with standard management.

Transl Androl Urol 2021 Aug;10(8):3423-3431

Department of Urology, Xiangya Hospital, Central South University, Changsha, China.

Background: Benign prostatic hyperplasia (BPH) is a common micturition disorder in middle-aged and elderly males, and it is one of the most common urology-related diseases worldwide. However, standard therapeutic drugs (α1-receptor blockers + 5α reductase inhibitors) do not provide anti-inflammatory or anti-infective effects. The Phellodendron Bawei tablet is a proprietary Chinese medicine with anti-inflammatory and anti-infective effects. Read More

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[Prosthetic repair of the aorta with a cadaveric homograft for infection of bifurcated synthetic vascular prosthesis].

Angiol Sosud Khir 2021 ;27(3):132-139

Department of Faculty Surgery, Samara State Medical University, Samara, Russia.

Infection of arterial vascular grafts is a rare but utterly severe complication in vascular surgery. Therapeutic policy in patients with graft infection has not been standardized, to be determined individually. One of the variants of surgical treatment is considered to be repeat aortic repair using a cadaveric graft. Read More

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September 2021

Functional outcomes and quality of life after surgical treatment of spinopelvic dissociation: a case series with one-year follow-up.

BMC Musculoskelet Disord 2021 Sep 15;22(1):795. Epub 2021 Sep 15.

Clinic of Rheumatology, Orthopaedics Traumatology and Reconstructive Surgery, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: Spinopelvic dissociation is a transverse sacral fracture in conjunction with a vertical fracture of the sacrum on both sides, which causes the dissociation of the upper sacrum and spine from the pelvis. The most common causes of these fractures are high energy injuries such as falls from height or motor vehicle accidents. Spinopelvic dissociation is rare and heterogenous with severe associated injuries. Read More

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September 2021

Demographic and clinical factors associated with early hospital Coronovirus disease 2019 deaths in a low middle income setting: A record-based analysis of 20,641 deaths from India.

Monaldi Arch Chest Dis 2021 Sep 14. Epub 2021 Sep 14.

Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh.

Understanding the demographic and clinical characteristics cases and deaths is essential for better clinical and public health management of coronavirus disease-2019 (COVID-19) in resource-limited settings. We analyzed the COVID-19 deaths reported from India, to describe the demographic and clinical characteristics and identify the factors associated with early hospital deaths (within one day of hospitalization) and survival duration. We conducted a record review of the publicly available data on COVID-19 deaths reported between January 30th and November 30th, 2020. Read More

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September 2021

[Effectiveness of arthroscopic 360° capsular release for frozen shoulder].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Sep;35(9):1141-1146

Department of Orthopedics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, P.R.China.

Objective: To investigate the effectiveness of arthroscopic 360° capsular release for frozen shoulder.

Methods: Between April 2018 and April 2019, 42 patients with frozen shoulders were treated with arthroscopic 360° capsular release. There were 13 males and 29 females, with an average age of 52. Read More

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September 2021

Dengue Myocarditis Complicated by COVID-19: A Case Report on Dual Viral Infection.

Cureus 2021 Aug 10;13(8):e17076. Epub 2021 Aug 10.

General Medicine, Government Medical College and Hospital, Chandigarh, IND.

During the ongoing pandemic of coronavirus disease 2019 (COVID-19), it is crucial for clinicians to have an insight into the emerging co-infections. As the dengue virus (DENV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have related symptomatology, a high index of suspicion is required for prompt diagnosis of concurrent infections involving these two pathogens, especially in the areas endemic for tropical diseases, i.e. Read More

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Ixekizumab for Patients with Plaque Psoriasis Affected by Multiple Sclerosis: Case report.

Sultan Qaboos Univ Med J 2021 Aug 29;21(3):488-490. Epub 2021 Aug 29.

Department of Dermatology, Hospital Universitario Virgen de la Victoria, Málaga, Spain.

Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system that shares similar immunopathogenic mechanisms with chronic plaque psoriasis, such as the overexpression of the Th17 pathway. We report a 50-year-old male patient with MS and severe chronic plaque psoriasis who presented to Hospital Virgen de la Victoria, Málaga, Spain, in 2019. He was successfully treated with ixekizumab (anti-interleukin [IL]-17A and IL-17A/F monoclonal antibody). Read More

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[High frequency ultrasound combined with ultrasound-guided core needle biopsy for the diagnosis of primary thyroid lymphoma].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Aug;56(8):858-862

Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou 310016, China.

To investigate the sonographic features of primary thyroid lymphoma (PTL) and to evaluate the clinical significance of ultrasound-guided core needle biopsy (US-CNB) in PTL. A total of 24 patients with suspected PTL in Sir Run Run Shaw Hospital from January 2013 to June 2018 were analyzed retrospectively. All cases were confirmed by pathology, of them 23 patients received US-CNB and 1 patient chose operation without US-CNB, including 5 males and 19 females, aged from 39 to 75 years old. Read More

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Rapid-onset clozapine-induced hyperglycaemia: pathways of glycaemic dysregulation.

BMJ Case Rep 2021 Sep 13;14(9). Epub 2021 Sep 13.

Endocrinology Department, Braga Hospital, Braga, Portugal.

Clozapine is an atypical antipsychotic used in refractory schizophrenia, also efficient in alleviating dyskinesia in Parkinson's disease. Despite its potency, this drug is associated with severe metabolic side effects, including increased risk for diabetes. We report the case of a 45-year-old overweight woman with Parkinson's disease who presented with rapid-onset hyperglycaemia within 2 months after starting clozapine for refractory dyskinaesia. Read More

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September 2021

Secondary cluster headache and numb chin syndrome as initial manifestation of high-grade B-lymphoma: a case report.

J Med Case Rep 2021 Sep 14;15(1):468. Epub 2021 Sep 14.

Instituto Nacional de Cancerologia - Compensar, Bogotá, Colombia.

Background: Cluster headache is a primary condition characterized by severe headache accompanied by trigeminal autonomic signs. By definition, it is not attributed to underlying etiologies; however, under certain clinical characteristics, secondary etiologies must be ruled out.

Case Presentation: We present the case of a 48-year-old Hispanic man with a history of episodic right orbital pain, lasting 30 minutes, associated with ipsilateral tearing, who prior to the onset of his symptoms reported loss of appetite, weight loss, and paresthesias in the right chin region. Read More

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September 2021

Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido.

Sex Med 2021 Sep 10;9(5):100426. Epub 2021 Sep 10.

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan.

Introduction: Decreased libido in middle-aged and elderly men is often difficult to treat, and identifying the risk factors affecting decreased libido is important for the clinical management of decreased libido. However, limited information is available regarding specific risk factors in this population.

Aim: The present study investigated the risk factors for decreased libido among middle-aged and elderly men. Read More

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September 2021

Massive hemoptysis causing mortality in a post COVID-19 infected Asian male patient: Presenting as pulmonary mucormycosis, pulmonary tuberculosis and later sino-nasal mucormycosis.

Respir Med Case Rep 2021 4;34:101511. Epub 2021 Sep 4.

Department of Internal Medicine, Maulana Azad Medical College, New Delhi, 11002, India.

While the developed nations are discussing giving a third dose of the COVID-19 vaccine to immunocompromised individuals, there are still challenges that are of global concern, especially in developing countries. The Delta variant which is predominantly responsible for the disease burden has now been reported in over 148 countries. The catastrophe caused in the Indian subcontinent has highlighted some associations, most notable being the unprecedented rise in the cases of mucormycosis in COVID-19 patients referred to as CAM (COVID-19 associated mucormycosis). Read More

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September 2021

Syndrome of Inappropriate Antidiuretic Hormone Secretion-Induced Encephalopathy in a Patient With COVID-19.

Cureus 2021 Jul 27;13(7):e16671. Epub 2021 Jul 27.

Pediatrics, Masafi Hospital, Alexandria, EGY.

Various electrolyte imbalances have been documented in coronavirus disease 2019 (COVID-19) patients who progress to severe acute respiratory syndrome coronavirus-2 infection. Patients with co-morbidities like diabetes, hypertension, obesity, ischemic heart disease, chronic kidney disease, and chronic obstructive pulmonary disease are more vulnerable to developing complications in the form of electrolyte disturbance. We report a case of acute severe hyponatremia in a middle-aged man who was admitted to the hospital with viral pneumonia due to a coronavirus-2 infection. Read More

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SARS-CoV-2 Antibody Isotypes in Systemic Lupus Erythematosus Patients Prior to Vaccination: Associations With Disease Activity, Antinuclear Antibodies, and Immunomodulatory Drugs During the First Year of the Pandemic.

Front Immunol 2021 27;12:724047. Epub 2021 Aug 27.

Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden.

Objectives: Impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic on individuals with arthritis has been highlighted whereas data on other rheumatic diseases, e.g., systemic lupus erythematosus (SLE), are scarce. Read More

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September 2021

Robust Antibody Responses to the BNT162b2 mRNA Vaccine Occur Within a Week After the First Dose in Previously Infected Individuals and After the Second Dose in Uninfected Individuals.

Front Immunol 2021 26;12:722766. Epub 2021 Aug 26.

Department of Gastroenterology, Yamanashi Central Hospital, Kofu, Japan.

Background: Vaccines against severe acute respiratory syndrome coronavirus 2 can trigger acquired immunity in infection-naïve individuals and offer a path toward ending the coronavirus disease pandemic that began in 2019. However, the kinetics of early antibody responses in vaccinated individuals remain poorly understood.

Method: We followed BNT162b2 mRNA-vaccinated health care workers (HCWs, N=108) including 103 infection-naïve and five previously infected individuals. Read More

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September 2021

Large Vessel Occlusion Causing Cerebral Ischemic Stroke in Previously Healthy Middle-Aged Recently Recovered from Severe COVID-19 Infection.

Int Med Case Rep J 2021 29;14:577-582. Epub 2021 Aug 29.

Neurology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Saudi Arabia.

Background: Severe acute respiratory syndrome coronavirus (SARS-CoV-2) due to novel coronavirus disease 2019 (COVID-19) has led to an unprecedented worldwide pandemic with diverse respiratory symptoms as well as systemic manifestations and complications. The neurological manifestations of COVID-19 include, but are not limited to, headache, cerebrovascular disease, and skeletal muscle injury.

Case Report: Herein, we present a case of stroke with large vessel occlusion in a middle-aged man, who recently recovered from severe SARS-CoV-2 infection. Read More

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Georgian Med News 2021 Jul-Aug(316-317):30-35

1Peoples' Friendship University of Russia, Moscow; Russia.

Posttraumatic brachial plexopathy - is an actual problem, which is usually seen after shoulder area trauma and is often accompanied with intraarticular pathology. In case of failed conservative treatment, open brachial plexus decompression is an effective procedure, however, it is pretty traumatic and is accompanied by number of complications and recurrences, what explains the necessity of development of low-traumatic, miniinvasive alternative techniques. Purpose - develop a new mini-invasive endoscopic technique of brachial plexus decompression. Read More

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September 2021

Huge cutaneous abscess and severe symptomatic hypercalcaemia secondary to infection in an immunocompetent patient.

BMJ Case Rep 2021 Sep 12;14(9). Epub 2021 Sep 12.

Division of Infectious Disease, Department of Internal Medicine, Chulalongkorn University Faculty of Medicine, Bangkok, Thailand

is among the most common non-tuberculous mycobacteria causing human infections. Apart from pulmonary infection, the most common infection caused by is skin and soft tissue infection, and it is very rare in immunocompetent people. In this report, we present a case of a huge cutaneous abscess caused by A 63-year-old man living in Bangkok presented with progressive pain at the left lateral chest wall for 3 weeks and altered mentation for a few days. Read More

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September 2021

Migration in times of pandemic: SARS-CoV-2 infection among the Warao indigenous refugees in Belém, Pará, Amazonia, Brazil.

BMC Public Health 2021 09 13;21(1):1659. Epub 2021 Sep 13.

Secretaria de Saúde do Município de Belém (SESMA), Belem, Brazil.

Background: The emergence of the new causative agent of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the city of Wuhan, China, in December 2019, and its spread worldwide, led the World Health Organization (WHO) to declare a pandemic. The disease has caused high mortality among traditional populations and the most socially vulnerable groups such indigenous and refugees. The present study aims to investigate the prevalence of anti-SARS-CoV-2 IgG antibodies in the population of Venezuelan indigenous Warao refugees residing in private and public shelters in the city of Belem, capital of Para State, in the Brazilian Amazon. Read More

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September 2021

Morbilliform rashes in a patient with COVID-19 infection: A case report.

JNMA J Nepal Med Assoc 2021 Apr 30;59(236):399-401. Epub 2021 Apr 30.

Shree Birendra Hospital, Chhauni, Kathmandu, Nepal.

As the current COVID-19 pandemic is evolving, skin lesions are being reported more, the most common skin manifestation being morbilliform rashes. We describe a patient of severe COVID-19 infection, 48-year-old who initially presented with fever, cough and constitutional symptoms who developed morbilliform macular rashes during his illness. The rash appeared on 6th day of illness in the trunk, arms with sparing of palms and soles, associated with itching. Read More

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Lidocaine for Reduction of Pain Induced by Propofol in a Tertiary Care Hospital: A Descriptive Cross-sectional Study.

JNMA J Nepal Med Assoc 2021 Apr 30;59(236):365-368. Epub 2021 Apr 30.

Department of Anaesthesiology, Patan Academy of Health Sciences, Lalitpur, Nepal.

Introduction: Propofol is the most frequently used anaesthetic agent. Despite various anaesthetic benefits, propofol is not without side effects, pain on injection being the most common adverse effect. This study aimed to find the grade of pain reduced due to the injection of propofol after administration of lidocaine. Read More

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Guillain Barre Syndrome associated with COVID-19 Infection: A Case Report.

JNMA J Nepal Med Assoc 2021 Aug 12;59(240):808-811. Epub 2021 Aug 12.

Department of Anesthesia, Patan Academy of Health Sciences, Lalitpur, Nepal.

Coronavirus Disease has become a global pandemic after its emergence at the end of 2019 as a cluster of pneumonia. Apart from respiratory symptoms, neurologic complications are also common, mostly in hospitalized patients. More than 80 percent of patients have neurological symptoms during their disease course of which most common is encephalopathy. Read More

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Bilateral Moraxella Keratitis in a Healthy Person after an Episode of Conjunctivitis: A Case Report.

JNMA J Nepal Med Assoc 2021 May 25;59(237):510-512. Epub 2021 May 25.

Tilganga Institute of Ophthalmology, Gaushala, Kathmandu, Nepal.

Moraxella species are gram-negative diplobacilli and are rare cause of bacterial keratitis. We report a case of a 55-year-old woman presented with pain, redness and profound decrease in vision in both eyes for 2 weeks. One month back she had been treated as acute follicular conjunctivitis elsewhere. Read More

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Double Eyelid Tape as a Treatment Option for Severe Ptosis in Patients with Myotonic Dystrophy Type 1: A Case Report.

Am J Phys Med Rehabil 2021 Sep 9. Epub 2021 Sep 9.

Department of Rehabilitation Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea Department of Rehabilitation Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Abstract: Myotonic dystrophy is a systemic disorder associated with progressive muscle weakness of the extremities and multi-organ dysfunction. This condition commonly affects the levator palpebrae superioris muscle, which leads to ptosis and eventually affects patients' activities of daily living. The effects of ptosis on activities of daily living are usually overlooked; therefore, the importance of treatment is underestimated, and surgical procedures are considered infeasible in patients with pre-existent levator palpebrae superioris muscle weakness. Read More

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September 2021

Extremely high troponin levels induced by septic shock: a case report.

J Med Case Rep 2021 Sep 11;15(1):466. Epub 2021 Sep 11.

Department of Emergency and Critical Care Medicine, Tokushima Red Cross Hospital, 103, Irinokuchi, Komatsushima-cho, Komatsushima City, Tokushima, 773-8502, Japan.

Background: Troponin levels can be elevated in various diseases other than acute myocardial infarction, including sepsis. In diseases without myocardial necrosis, the elevated troponin levels are relatively low and normalize quickly.

Case Presentation: A 61-year-old Japanese man with impaired consciousness was transported to our hospital. Read More

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September 2021