Food Funct 2021 Jun 11. Epub 2021 Jun 11.
Department of Food Science and Engineering, College of Agriculture, Yanbian University, Yanji 133000, Jilin, China. and Department of Food Science and Engineering, College of Integration Science, Yanbian University, Yanji 133000, Jilin, China.
This study investigated lipid metabolism regulation by anthocyanins from Aronia melanocarpa (AAM) in 3T3-L1 preadipocytes and high fat diet (HFD) mice. Ultra-performance liquid chromatography/ion mobility quadrupole time-of-flight mass spectrometry analysis identified the constituents of AAM, which decreased lipid content and inflammation in 3T3-L1 cells without cytotoxicity. Meanwhile, taking normal diet and orlistat mice as references, AAM supplementation improved blood lipid levels and adipocyte degeneration, promoted beneficial gut microbial growth, and maintained lipid metabolism in HFD mice. Read More