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Spatialization of saturated hydraulic conductivity using the Bayesian Maximum Entropy method: Application to wastewater infiltration areas.

Water Res 2021 Aug 28;204:117607. Epub 2021 Aug 28.

INRAE, REVERSAAL, F-69626 Villeurbanne Cedex, France.

Wastewater treatment, a major issue at the European level, focuses on improving surface water and groundwater quality, preserving the receiving environment, and ensuring a sustainable use of water. Soil infiltration is increasingly practiced downstream of wastewater treatment plants, particularly in rural areas without surface water bodies, as is the use of soil as an additional buffer and treatment step. However, the design of infiltration areas on heterogeneous soils remains an extremely complex task due to the costly and time-consuming spatial measurement of saturated hydraulic conductivity (Ks). Read More

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The emergence of machine learning in auditory neural impairment: a systematic review.

Neurosci Lett 2021 Sep 15:136250. Epub 2021 Sep 15.

Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Hearing loss is a common neurodegenerative disease that can start at any stage of life. Misalignment of the auditory neural impairment may impose challenges in processing incoming auditory stimulus that can be measured using electroencephalography (EEG). The electrophysiological behaviour response emanated from EEG auditory evoked potential (AEP) requires highly trained professionals for analysis and interpretation. Read More

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September 2021

Body size estimation in obesity: a systematic review and meta-analysis.

Exp Brain Res 2021 Sep 18. Epub 2021 Sep 18.

Center for Mind/Brain Sciences, CIMeC, University of Trento, Corso Bettini, 31, 38068, Rovereto, TN, Italy.

Previous research about body size estimation in obesity reported heterogeneous results. This might be related to the fact that the tasks adopted explored different body representations. Classifying the previous studies according to the specific body representation probed (i. Read More

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September 2021

Long-term Antibiotic Treatment in Pouchitis-Patterns of Use and Safety.

Inflamm Bowel Dis 2021 Sep 18. Epub 2021 Sep 18.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Introduction: Pouchitis, often developing after colectomy and ileal pouch-anal anastomosis for ulcerative colitis, is highly responsive to antibiotics. Ciprofloxacin and/or metronidazole are commonly used, often for prolonged periods. We report patterns of antibiotic use, adverse events, and resistant infections in patients with pouchitis with long-term antibiotic treatment. Read More

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September 2021

What reveals the right ventricle about prognosis in heart failure, and why appear metrics to be sex-specific?

J Clin Ultrasound 2021 Sep 18. Epub 2021 Sep 18.

Department of Emergency Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

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September 2021

Improving the robustness of MOLLI T1 maps with a dedicated motion correction algorithm.

Sci Rep 2021 Sep 17;11(1):18546. Epub 2021 Sep 17.

Hospital Clínic de Barcelona, Barcelona, Spain.

Myocardial tissue T1 constitutes a reliable indicator of several heart diseases related to extracellular changes (e.g. edema, fibrosis) as well as fat, iron and amyloid content. Read More

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September 2021

Image intensity histograms as imaging biomarkers: application to immune-related colitis.

Biomed Phys Eng Express 2021 Sep 17. Epub 2021 Sep 17.

7033 Wisconsin Institute for Medical Research Department of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Madison, Wisconsin, 53706, UNITED STATES.

Purpose To investigate image intensity histograms as a potential source of useful imaging biomarkers in both a clinical example of detecting immune-related colitis (irColitis) inF-FDG PET/CT images of immunotherapy patients and an idealized case of classifying digital reference objects (DRO). Methods Retrospective analysis of bowelF-FDG uptake in N=40 patients receiving immune checkpoint inhibitors was conducted. A CNN trained to segment the bowel was used to generate the histogram of bowelF-FDG uptake, and percentiles of the histogram were considered as potential metrics for detecting inflammation associated with irColitis. Read More

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September 2021

Cross-oceanic distribution and origin of microplastics in the subsurface water of the South China Sea and Eastern Indian Ocean.

Sci Total Environ 2021 Sep 10;805:150243. Epub 2021 Sep 10.

State Key Laboratory of Estuarine and Costal Research, East China Normal University, Shanghai 200062, China; Plastic Marine Debris Research Center, East China Normal University, Shanghai 200241, China; Region Training and Research Center on Plastic Marine Debris and Microplastics, IOC-UNESCO, 200241, China. Electronic address:

Marine microplastic (MP) pollution is a global environmental problem that has received attention from scientific researchers and the public for the past several decades. However, without a suitably large-volume sampling method, the presence of MPs in subsurface water (< 5 m) is poorly understood. Here, MP content in subsurface water was determined using a pump-underway ship intake system along the cross-oceanic transect from the Pearl River Estuary to the Indian Ocean. Read More

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September 2021

Ranking Sets of Morbidities using Hypergraph Centrality.

J Biomed Inform 2021 Sep 14:103916. Epub 2021 Sep 14.

Health Data Research-UK, Swansea University, Singleton Park, Swansea, SA1 8PP.

Multi-morbidity, the health state of having two or more concurrent chronic conditions, is becoming more common as populations age, but is poorly understood. Identifying and understanding commonly occurring sets of diseases is important to inform clinical decisions to improve patient services and outcomes. Network analysis has been previously used to investigate multi-morbidity, but a classic application only allows for information on binary sets of diseases to contribute to the graph. Read More

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September 2021

Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.

Immunity 2021 Sep 13. Epub 2021 Sep 13.

Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address:

How T cell receptor (TCR) signal strength modulates T cell function and to what extent this is modified by immune checkpoint blockade (ICB) are key questions in immunology. Using Nr4a3-Tocky mice, we characterized early quantitative and qualitative changes that occur in CD4 T cells in relation to TCR signaling strength. We captured how dose- and time-dependent programming of distinct co-inhibitory receptors rapidly recalibrates T cell activation thresholds and visualized the immediate effects of ICB on T cell re-activation. Read More

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September 2021

Chromosome-scale reference genome assembly of a diploid potato clone derived from an elite variety.

G3 (Bethesda) 2021 Sep 17. Epub 2021 Sep 17.

Institute for Quantitative Genetics and Genomics of Plants, Universitätsstraße 1, 40225 Düsseldorf, Germany.

Potato (Solanum tuberosum L.) is one of the most important crops with a world-wide production of 370 million metric tons. The objectives of this study were (i) to create a high quality consensus sequence across the two haplotypes of a diploid clone derived from a tetraploid elite variety and assess the sequence divergence from the available potato genome assemblies, as well as among the two haplotypes; (ii) to evaluate the new assembly's usefulness for various genomic methods and (iii) to assess the performance of phasing in diploid and tetraploid clones, using linked read sequencing technology. Read More

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September 2021

Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level.

PLoS Comput Biol 2021 Sep 17;17(9):e1009305. Epub 2021 Sep 17.

Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine; Baltimore, Maryland, United States of America.

The immaturity of pluripotent stem cell (PSC)-derived tissues has emerged as a universal problem for their biomedical applications. While efforts have been made to generate adult-like cells from PSCs, direct benchmarking of PSC-derived tissues against in vivo development has not been established. Thus, maturation status is often assessed on an ad-hoc basis. Read More

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September 2021

Learning Modal-Invariant Angular Metric by Cyclic Projection Network for VIS-NIR Person Re-identification.

IEEE Trans Image Process 2021 Sep 17;PP. Epub 2021 Sep 17.

Person re-identification across visible and near-infrared cameras (VIS-NIR Re-ID) has widespread applications. The challenge of this task lies in heterogeneous image matching. Existing methods attempt to learn discriminative features via complex feature extraction strategies. Read More

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September 2021

Experimental Measurement of the Divergent Quantum Metric of an Exceptional Point.

Phys Rev Lett 2021 Sep;127(10):107402

Beijing Key Laboratory for Optical Materials and Photonic Devices, Department of Chemistry, Capital Normal University, Beijing 100048, People's Republic of China.

The geometry of Hamiltonian's eigenstates is encoded in the quantum geometric tensor (QGT), containing both the Berry curvature, central to the description of topological matter, and the quantum metric. So far, the full QGT has been measured only in Hermitian systems, where the role of the quantum metric is mostly limited to corrections. On the contrary, in non-Hermitian systems, and, in particular, near exceptional points, the quantum metric is expected to diverge and to often play a dominant role, for example, in the enhanced sensing and in wave packet dynamics. Read More

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September 2021

Hand grip strength in boys and girls from summer school camps in Spain, 1900-1925. A comparison with 21st century data.

Am J Hum Biol 2021 Sep 17:e23681. Epub 2021 Sep 17.

Grupo de Investigación Epinut, Universidad Complutense de Madrid, Madrid, Spain.

Objectives: The Spanish National Pedagogic Museum (Museo Pedagógico Nacional, MPN), founded by La Institución Libre de Enseñanza, organized the first summer school camps in Spain and their initiative was followed by other institutions in this country. MPN prepared anthropological forms for those sojourns, which included information about both metric and physiological measurements of the schoolchildren. The aim of the current work is to analyze hand grip strength data and to compare them with recent values. Read More

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September 2021

Machine learning to investigate superficial white matter integrity in early multiple sclerosis.

J Neuroimaging 2021 Sep 17. Epub 2021 Sep 17.

Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.

Background And Purpose: This study aims todetermine the sensitivity of superficial white matter (SWM) integrity as a metric to distinguish early multiple sclerosis (MS) patients from healthy controls (HC).

Methods: Fractional anisotropy and mean diffusivity (MD) values from SWM bundles across the cortex and major deep white matter (DWM) tracts were extracted from 29 early MS patients and 31 age- and sex-matched HC. Thickness of 68 cortical regions and resting-state functional-connectivity (RSFC) among them were calculated. Read More

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September 2021

Direct continuous electromyographic control of a powered prosthetic ankle for improved postural control after guided physical training: A case study.

Wearable Technol 2021 12;2. Epub 2021 Apr 12.

Joint Department of Biomedical Engineering, North Carolina State University and University of North Carolina at Chapel Hill, Raleigh, North Carolina 27606, USA.

Despite the promise of powered lower limb prostheses, existing controllers do not assist many daily activities that require continuous control of prosthetic joints according to human states and environments. The objective of this case study was to investigate the feasibility of direct, continuous electromyographic (dEMG) control of a powered ankle prosthesis, combined with physical therapist-guided training, for improved standing postural control in an individual with transtibial amputation. Specifically, EMG signals of the residual antagonistic muscles (i. Read More

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Detection of hypomimia in patients with Parkinson's disease via smile videos.

Ann Transl Med 2021 Aug;9(16):1307

Technical Department, Hangzhou Healink Technology Corporation Limited, Hangzhou, China.

Background: Parkinson's disease (PD) is a neurodegenerative disease characterized by the impairment of facial expression, known as hypomimia. Hypomimia has serious impacts on patients' ability to communicate, and it is difficult to detect at early stages of the disease. Furthermore, due to bradykinesia or other reasons, it is inconvenient for PD patients to visit the hospital. Read More

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Comparison of Energy Expenditure Assessed Using Wrist- and Hip-Worn ActiGraph GT3X in Free-Living Conditions in Young and Older Adults.

Front Med (Lausanne) 2021 31;8:696968. Epub 2021 Aug 31.

University of Limoges, HAVAE, EA 6310, Limoges, France.

The World Health Organization has presented their recommendations for energy expenditure to improve public health. Activity trackers do represent a modern solution for measuring physical activity, particularly in terms of steps/day and energy expended in physical activity (active energy expenditure). According to the manufacturer's instructions, these activity trackers can be placed on different body locations, mostly at the wrist and the hip, in an undifferentiated manner. Read More

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Metric studies of the compliance questionnaire on rheumatology (CQR): A case of validity induction?

Reumatol Clin (Engl Ed) 2021 Sep 13. Epub 2021 Sep 13.

Universidad Católica Los Ángeles de Chimbote, Chimbote, Peru. Electronic address:

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September 2021

Hybrid COVID-19 segmentation and recognition framework (HMB-HCF) using deep learning and genetic algorithms.

Artif Intell Med 2021 Sep 28;119:102156. Epub 2021 Aug 28.

Computer Engineering and Control Systems Department, Faculty of Engineering, Mansoura University, Egypt. Electronic address:

COVID-19 (Coronavirus) went through a rapid escalation until it became a pandemic disease. The normal and manual medical infection discovery may take few days and therefore computer science engineers can share in the development of the automatic diagnosis for fast detection of that disease. The study suggests a hybrid COVID-19 framework (named HMB-HCF) based on deep learning (DL), genetic algorithm (GA), weighted sum (WS), and majority voting principles in nine phases. Read More

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September 2021

Use of PCR in the diagnosis of pericardial amebiasis: a case report and systematic review of the literature.

BMC Infect Dis 2021 Sep 16;21(1):960. Epub 2021 Sep 16.

Department of Infectious Diseases, St. Luke's International Hospital, 9-1, Akashi-cho, Chuo-ku, Tokyo, Japan.

Background: Entamoeba histolytica (E. histolytica) is rarely identified as a cause of amebic pericarditis. We report a case of amebic pericarditis complicated by cardiac tamponade, in which the diagnosis was missed initially and was made retrospectively by polymerase chain reaction (PCR) testing of a stored sample of pericardial fluid. Read More

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September 2021

Gardnerella vaginalis in urinary tract infections, are men spared?

Anaerobe 2021 Sep 14;72:102438. Epub 2021 Sep 14.

Department of Medical Microbiology, Medical University of Sofia, Sofia, Bulgaria.

Gardnerella vaginalis in association with anaerobes has been linked to bacterial vaginosis in women, while urinary tract infections (UTIs) in men have rarely been reported. The aim of the review was to reveal the significance of G. vaginalis UTIs in men. Read More

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September 2021

Validity of caregivers' reports on prior use of antibacterials in children under five years presenting to health facilities in Gulu, northern Uganda.

PLoS One 2021 16;16(9):e0257328. Epub 2021 Sep 16.

Department of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.

Introduction: Given the frequent initiation of antibacterial treatment at home by caregivers of children under five years in low-income countries, there is a need to find out whether caregivers' reports of prior antibacterial intake by their children before being brought to the healthcare facility are accurate. The aim of this study was to describe and validate caregivers' reported use of antibacterials by their children prior to seeking care at the healthcare facility.

Methods: A cross sectional study was conducted among children under five years seeking care at healthcare facilities in Gulu district, northern Uganda. Read More

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September 2021

Exchanging registered users' submitting reviews towards trajectory privacy preservation for review services in Location-Based Social Networks.

PLoS One 2021 16;16(9):e0256892. Epub 2021 Sep 16.

State Key Laboratory of Public Big Data, College of Computer Science and Technology, Guizhou University, Guiyang, China.

In Location-Based Social Networks (LBSNs), registered users submit their reviews for visited point-of-interests (POIs) to the system providers (SPs). The SPs anonymously publish submitted reviews to build reputations for POIs. Unfortunately, the user profile and trajectory contained in reviews can be easily obtained by adversaries who SPs has compromised with. Read More

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September 2021

Balance-Aware Grid Collage for Small Image Collections.

IEEE Trans Vis Comput Graph 2021 Sep 16;PP. Epub 2021 Sep 16.

Grid collages (GClg) of small image collections are popular and useful in many applications, such as personal album management, online photo posting, and graphic design. In this study, we focus on how visual effects influence individual preferences through various arrangements of multiple images under such scenarios. A novel balance-aware metric is proposed to bridge the gap between multi-image joint presentation and visual pleasure. Read More

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September 2021

Improving Deep Metric Learning by Divide and Conquer.

IEEE Trans Pattern Anal Mach Intell 2021 Sep 16;PP. Epub 2021 Sep 16.

Deep metric learning aims at learning a mapping from the input domain to an embedding space, where semantically similar objects are located nearby and dissimilar objects far from another. However, while the embedding space learns to mimic the user-provided similarity on the training data, it should also generalize to novel categories not seen during training. Besides user-provided training labels, a lot of additional visual factors (such as viewpoint changes or shape peculiarities) exist and imply different notions of similarity between objects, affecting the generalization on novel images. Read More

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September 2021

Effect of Helicobacter pylori eradication therapy on clinical and laboratory biomarkers associated with gastric damage in healthy school-aged children: A randomized non-blinded trial.

Helicobacter 2021 Sep 15:e12853. Epub 2021 Sep 15.

Microbiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile.

Objectives: Helicobacter pylori (H. pylori) is the primary cause of gastric cancer and eradication in healthy adults has proven effective in decreasing cancer incidence. H. Read More

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September 2021

Consumer-based activity trackers in evaluation of physical activity in myositis patients.

Rheumatology (Oxford) 2021 Sep 16. Epub 2021 Sep 16.

Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Objectives: Inflammatory myopathies are characterized by muscle weakness that limit activities of daily living. Daily step count is an accepted metric of physical activity. Wearable technologies such as Fitbit® enable tracking of daily step counts. Read More

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September 2021

Left Ventricular Global Function Index and the Impact of its Companion Metric.

Front Cardiovasc Med 2021 30;8:695883. Epub 2021 Aug 30.

Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands.

Left ventricular (LV) global function index (LVGFI) has been introduced as a volume-based composite metric for evaluation of ventricular function. The definition formula combines stroke volume (SV), end-systolic volume (ESV), end-diastolic volume (EDV) and LV mass/density. Being a dimensionless ratio, this new metric has serious limitations which require evaluation at a mathematical and clinical level. Read More

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