Obesity (Silver Spring) 2021 Apr 3. Epub 2021 Apr 3.
Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Objective: Identifying predictors of weight loss and clinical outcomes may increase understanding of individual variability in weight loss response. We hypothesized that baseline multiomic features, including DNA methylation (DNAme), metabolomics, and gut microbiome, would be predictive of short-term changes in body weight and other clinical outcomes within a comprehensive weight loss intervention.
Methods: Healthy adults with overweight or obesity (n = 62, age 18-55 years, BMI 27-45 kg/m , 75. Read More