Med Image Anal 2021 Jun 2;72:102107. Epub 2021 Jun 2.
Division of Respirology, Department of Medicine, Western University, London, ON, N6A 5B7, Canada; Robarts Research Institute, School of Biomedical Engineering, Western University, London, ON, N6A 5B7, Canada. Electronic address:
Ultra-short echo-time (UTE) magnetic resonance imaging (MRI) provides enhanced visualization of pulmonary structural and functional abnormalities and has shown promise in phenotyping lung disease. Here, we describe the development and evaluation of a lung segmentation approach to facilitate UTE MRI methods for patient-based imaging. The proposed approach employs a k-means algorithm in kernel space for pair-wise feature clustering and imposes image domain continuous regularization, coined as continuous kernel k-means (CKKM). Read More