303 results match your criteria metastases rectosigmoid


Histopathological Significance and Prognostic Impact of Tumor Budding in Colorectal Cancer

Asian Pac J Cancer Prev 2018 Sep 26;19(9):2447-2453. Epub 2018 Sep 26.

Department of Laboratory Services, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.

Background: Colorectal cancer (CRC) is a heterogeneous disease with a complex etiology. New prognostic factors need to be investigated. Our present focus is on histopathological significance and prognostic impact of tumor budding in CRC. Read More

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September 2018

First Ever Robotic Stage One ALPPS Procedure in India: for Colorectal Liver Metastases.

Indian J Surg 2018 Jun 21;80(3):269-271. Epub 2017 Dec 21.

Department of HPB surgery & Liver Transplantation, HCG Hospital, Bengaluru, 560027 India.

Twenty five percent of total liver volume (TLV) is considered as the ideal functional liver remnant (FLR) in major liver resections. In patients with macro-vesicular steatosis, early cirrhosis, and post-neoadjuvant chemotherapy (NACT), hepatocellular injury is common. In such instances, up to 40% of FLR may be required. Read More

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Incidence of suspicious axillary lymph node involvement in fluorine-18 fluoro-D-glucose positron emission tomography/computed tomography in gynecologic cancers.

Turk J Obstet Gynecol 2018 Jun 21;15(2):99-104. Epub 2018 Jun 21.

Süleyman Demirel University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Isparta, Turkey.

Objective: There is scarce information about axillary lymph node involvement in gynecologic cancers. We analyzed the incidence of suspicious axillary lymph nodes in gynecologic cancers.

Materials And Methods: We retrospectively analyzed the positron emission tomography/computed tomography findings of 251 patients with endometrial, cervical, and ovarian cancer. Read More

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A case of laparoscopic high anterior resection of rectosigmoid colon cancer associated with a horseshoe kidney using preoperative 3D-CT angiography.

Surg Case Rep 2018 Jun 27;4(1):66. Epub 2018 Jun 27.

Department of Surgery, Nagano Prefectural Shinshu Medical Center, Suzaka, 1332, Suzakashi, Nagano, 382-8577, Japan.

Background: Horseshoe kidney is a congenital malformation in which the bilateral kidneys are fused. It is frequently complicated by other congenital malformations and is often accompanied by anomalies of the ureteropelvic and vascular systems, which must be evaluated to avoid iatrogenic injury. We report a case of laparoscopic high anterior resection of rectosigmoid colon cancer associated with a horseshoe kidney using preoperative 3D-CT angiography. Read More

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Lymph Node Yield After Neoadjuvant Chemoradiotherapy in Rectal Cancer Specimens: A Randomized Trial Comparing Two Fixatives.

Dis Colon Rectum 2018 08;61(8):888-896

Department of Gastroenterology, Hospital das Clinicas, Cancer Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil.

Background: It is widely reported that neoadjuvant chemoradiation reduces lymph node yield in rectal cancer specimens. Some have questioned the adequacy of finding ≥12 lymph nodes for accurate staging, and fewer nodes were correlated with good response. Others reported that low lymph node count raises the chance for understaging and correlates with worse survival. Read More

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Multiple subcutaneous metastases as the solitary presenting site of colorectal cancer.

J Cancer Res Ther 2018 Apr-Jun;14(3):716-718

Department of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Skin metastases, as a presenting symptom of gastrointestinal malignancies, are very rare and signify aggressive disease. They usually occur after a long period of diagnosis and along with other visceral metastases. We present the case of an 18-year-old male with diffuse subcutaneous metastases as a presenting feature and as the only site of distant metastases due to rectosigmoid adenocarcinoma. Read More

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November 2018

Metastatic ductal carcinoma of the breast to colonic mucosa.

BMJ Case Rep 2018 May 26;2018. Epub 2018 May 26.

Department of Surgery, University of Saskatchewan College of Medicine, Saskatoon, Saskatchewan, Canada.

Breast cancer is the most common malignancy among women, while invasive ductal carcinoma is the most common type of invasive breast cancer. Metastatic spread to the colon and rectum in breast cancer is rare. This report describes a case of a 69-year-old woman with metastatic ductal breast cancer to the rectosigmoid, presenting as an incidental finding on screening colonoscopy. Read More

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Primary splenic malignant lymphoma mimicking metastasis of rectosigmoid cancer: A case report.

Int J Surg Case Rep 2018 9;44:11-15. Epub 2018 Feb 9.

Department of Surgery, Kinki Central Hospital, 3-1 Kurumaduka, Itami, Hyogo 664-8533, Japan.

Introduction: Primary splenic malignant lymphoma is quite a rare disease, and its preoperative diagnosis is difficult.

Case Presentation: An 80-year-old man was diagnosed with advanced rectosigmoid cancer with liver and splenic metastases, for which he underwent single-incision laparoscopic high anterior resection for the primary rectosigmoid cancer. After chemotherapy, he underwent laparoscopy-assisted splenectomy and open partial hepatectomy of segment 3 and segment 5/6 of the liver. Read More

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February 2018

[A Case of Bladder Metastasis Occurring after Rectosigmoid Cancer Operation].

Gan To Kagaku Ryoho 2017 Nov;44(12):1417-1419

Dept. of Digestive Surgery, Tsushimi Hospital.

A 55-year-old man was admitted to our hospital for rectosigmoid(RS)cancer. We performed high anterior resection in the patient. Pathological findings showed mucinous adenocarcinoma, pT3(SS), pN1, sM0, sP0, pCy0, fStage III a. Read More

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November 2017

[Two Cases of Achieving a Pathological Complete Response via Hepatic Arterial Infusion Chemotherapy for Liver-Limited and Unresectable Liver Metastases from Colorectal Cancer with RAS Mutations].

Gan To Kagaku Ryoho 2017 Nov;44(12):1329-1331

Division of Lower Gastrointestinal Surgery, Dept of Surgery, Hyogo College of Medicine.

We had 2 cases of liver-limited and unresectable liver metastases from colorectal cancer with RAS mutations. These patients received hepatic arterial infusion chemotherapy(HAI), finally achieving pCR. Case 1 was a 76-year-old female with rectosigmoid cancer and multiple liver metastases. Read More

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November 2017

[Multiple Resections for Metastases from Colorectal Cancer].

Gan To Kagaku Ryoho 2018 Jan;45(1):100-102

Dept. of Surgery, Tokyo Women's Medical University Medical Center East.

Purpose: We analyzed to clarify an outcome of multiple resections of metastases from colorectal cancer.

Patients And Method: Total 7 cases who underwent several resections for metastases from colorectal cancer in Saiseikai Kurihashi Hospital after 2010 were enrolled for analysis.

Result: Age of patients at the time of the primary site resection was 67(45-78)year-old, including 4males and 3 females. Read More

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January 2018

Differences in Cancer-Specific Mortality of Right- Versus Left-Sided Colon Adenocarcinoma: A Surveillance, Epidemiology, and End Results Database Analysis.

JCO Clin Cancer Inform 2017 11;1:1-9

All authors: University of California Los Angeles, Los Angeles, CA.

Purpose: Studies have shown an increased risk for all-cause mortality with right-sided colon cancer (RCC) as compared with left-sided colon cancer (LCC). However, these studies were unable to directly account for mortality events unrelated to cancer, known as other-cause mortality. We investigated the difference in cancer-specific mortality (CSM) between RCC and LCC at localized, regional, and metastatic stages, according to the Fine and Gray proportional hazards model, while accounting for other-cause mortality as a competing risk. Read More

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November 2017

Capecitabine versus S-1 as adjuvant chemotherapy for patients with stage III colorectal cancer (JCOG0910): an open-label, non-inferiority, randomised, phase 3, multicentre trial.

Lancet Gastroenterol Hepatol 2018 01 24;3(1):47-56. Epub 2017 Oct 24.

National Cancer Center Hospital, Tokyo, Japan.

Background: Adjuvant chemotherapy with oral fluoropyrimidine alone after D3/D2 lymph node dissection improves disease-free survival and overall survival in patients with stage III colon cancer. Adjuvant S-1 has been shown to be non-inferior to uracil and tegafur plus leucovorin in terms of disease-free survival. This study aims to confirm the non-inferiority of S-1 compared with capecitabine as adjuvant treatment in patients with stage III colorectal cancer. Read More

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January 2018

A New Prediction Model for Local Recurrence After Curative Rectal Cancer Surgery: Development and Validation as an Asian Collaborative Study.

Dis Colon Rectum 2017 Nov;60(11):1168-1174

1 Department of Surgery, Kyoto University Hospital, Kyoto, Japan 2 Department of Surgery, Kyungpook National University Medical Center, Daegu, South Korea.

Background: Local recurrence is one of the remaining problems in rectal and rectosigmoid cancer, and it is sometimes difficult to treat.

Objective: This study aimed to explore various factors that are highly related to local recurrence and to develop a new prediction model for local recurrence after curative resection.

Design: This is a retrospective cohort study SETTINGS:: This study was conducted at 2 academic hospitals in Japan and Korea. Read More

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November 2017

Laparoscopic-Assisted Resection for Advanced Colorectal Cancer in Solid Organ Transplant Recipients.

J Invest Surg 2018 Dec 19;31(6):483-490. Epub 2017 Sep 19.

c Department of General Surgery , Peking Union Medical College Hospital, Chinese Academy of Medical Sciences , Beijing , China.

Aim: To evaluate the feasibility, short- and long-term outcomes, and safety of laparoscopic resection for advanced colorectal cancer (CRC) in solid organ transplant recipients.

Methods: Between September 2001 and April 2016, five patients who underwent laparoscopic-assisted resection for CRC after solid organ transplantation were included in this study. Their clinical data were retrospectively analyzed with regard to patient demographics, immunosuppressive therapy, tumor characteristics, surgical outcomes, and follow-up data. Read More

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December 2018

A case of ovarian growing teratoma syndrome treated by cytoreductive surgery.

Int Cancer Conf J 2017 Oct 3;6(4):188-192. Epub 2017 Aug 3.

Department of Peritoneal Surface Malignancy Center, Kusatsu General Hospital, 1660, Yabase, Kusatsu, Shiga 525-8585 Japan.

Ovarian growing teratoma syndrome (GTS) is a rare disease characterized by growth of a benign tumor during or after chemotherapy, following the removal of germ cell gonadal cancers. Although benign, GTS tumors grow gradually and may compress surrounding organs. In addition, up to 3% of GTS cases can undergo malignant transformation. Read More

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October 2017

Using indocyanine green fluorescent imaging to successfully resect metachronous regional lymph node recurrence of rectosigmoid cancer.

Asian J Endosc Surg 2018 Feb 13;11(1):47-49. Epub 2017 Jul 13.

Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.

A 39-year-old female patient underwent anterior resection with locoregional lymph node dissection for rectosigmoid cancer at another hospital. The procedure involved transection of the superior rectal artery just below the origin of the left colic artery. Postoperative diagnosis was stage III B. Read More

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February 2018

Associating liver partition and portal vein ligation for staged hepatectomy: A surgical technique for liver resections.

J Res Med Sci 2017 26;22:52. Epub 2017 Apr 26.

Department of General Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel surgical technique liver resection in traditionally nonresectable primary intrahepatic tumors or colorectal liver metastases.

Materials And Methods: From June 2013 to March 2014, patients with primary tumor of liver or colorectal tumors with liver metastasis were selected to evaluate whether they met the initial criteria for ALPPS procedure.

Results: Nine patients enrolled in the study with primary diagnoses of colon and rectosigmoid cancer, carcinoid tumor, gastrointestinal stromal tumor of small intestine, hepatocellular carcinoma, and pancreatic neuroendocrine tumor (PNET). Read More

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Circulating tumor cells in different stages of colorectal cancer.

Folia Histochem Cytobiol 2017 ;55(1):1-5

University Hospital Kralovske Vinohrady Department of Laboratory Genetics, Srobarova 50, 100 34, Prague, Czech Republic.

Introduction: Liquid biopsies are noninvasive tests using blood or body fluids to detect circulating tumor cells (CTCs) or the products of tumor cells, such as fragments of nucleic acids or proteins that are shed into biological fluids from primary tumor or its metastates. The analysis of published clinical studies provides coherent evidence that the presence of CTCs detected in peripheral blood is a strong prognostic factor in patients with colorectal carcinoma (CRC). The aim of the study was to implement size-based separation protocol of CTCs in CRC patients. Read More

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Histopathological Significance and Prognostic Impact of Tumor Budding in Colorectal Cancer.

Ann Clin Lab Sci 2017 Mar;47(2):129-135

Department of Research, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.

Background: Colorectal cancer (CRC) is a heterogeneous disease with complex etiology. New prognostic factors for this group of disease need to be investigated. This study evaluated the histopathological significance and prognostic impact of tumor budding in CRC. Read More

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Survival outcomes following laparoscopic versus open D3 dissection for stage II or III colon cancer (JCOG0404): a phase 3, randomised controlled trial.

Lancet Gastroenterol Hepatol 2017 04 2;2(4):261-268. Epub 2017 Feb 2.

Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan.

Background: Although benefits of laparoscopic surgery compared with open surgery have been suggested, the long-term survival of patients undergoing laparoscopic surgery for colon cancer requiring Japanese D3 dissection remains unclear. We did a randomised controlled trial to establish non-inferiority of laparoscopic surgery to open surgery.

Methods: We did an open-label, multi-institutional, randomised, two-arm phase 3 trial in 30 hospitals in Japan. Read More

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The Role of Routine Peritoneal and Omental Biopsies at Risk-Reducing Salpingo-Oophorectomy.

J Minim Invasive Gynecol 2017 Jul - Aug;24(5):772-776. Epub 2017 Mar 8.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas. Electronic address:

Study Objective: To assess the potential role of peritoneal and omental biopsies in women undergoing risk-reducing salpingo-oopherectomy (RRSO) for prophylactic management of hereditary breast/ovarian cancer (HBOC) syndromes.

Design: A retrospective observational cohort (Canadian Task Force classification II.1). Read More

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February 2018

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.

Oncotarget 2017 Jun;8(26):42198-42213

Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.

Background: Recent molecular characterization of colorectal tumors has identified several molecular alterations of interest that are considered targetable in metastatic colorectal cancer (mCRC).

Methods: We conducted a single-institution, retrospective study based on comprehensive genomic profiling of tumors from 138 patients with mCRC using next-generation sequencing (NGS) via FoundationOne.

Results: Overall, RAS mutations were present in 51. Read More

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Using our own developed stent in the palliative treatment of obstruction in the left half of the colon due to ovarian cancer.

Ginekol Pol 2017 ;88(1):1-4

1st Chair and Department of General, Vascular and Oncologic Surgery, 2nd Faculty of Medicine, Warsaw Medical University, Poland 2nd Chair and Department of Obstetrics, Gynecology and Oncology 2nd Faculty of Medicine, Warsaw Medical University, Poland.

Objectives: An assessment of implantation efficacy and safety of self-developed self-expanding stent in patients with an ovarian cancer induced by intestinal obstruction.

Material And Methods: The study of the stenting efficacy and safety was realized prospectively. The group consisted of 13 patients with left half colon obstruction due to an inoperable metastatic ovarian carcinoma. Read More

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[A Case of Unresectable Advanced Rectal Cancer with a Pancreatic Tumor That Was Successfully Treated with FOLFIRINOX].

Gan To Kagaku Ryoho 2016 Nov;43(12):2468-2470

Dept. of Surgery, Ogikubo Hospital.

A 72-year-old man was admitted to our hospital department in September 2014 because of a positive fecal occult blood test.Colonoscopy showed a type 2 tumor in half of the AV 15 cm rectosigmoid colon.Histology of the biopsy indicated a moderately differentiated adenocarcinoma, and the RAS gene test found wild type. Read More

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November 2016

[Three Cases of Unresectable, Advanced, and Recurrent Colorectal Cancer Associated with Gastrointestinal Obstruction That Were Treated with Small Intestine-Transverse Colon Bypass Surgery].

Gan To Kagaku Ryoho 2016 Nov;43(12):1632-1634

Dept. of Surgery, Tokyo Women's Medical University Medical Center East.

Herein, we report 3cases of unresectable, advanced, and recurrent colorectal cancer associated with gastrointestinal obstruction. The patients were treated with small intestine-transverse colon bypass surgery, which improved the quality of life (QOL)in all cases. Case 1 was an 80-year-old woman who presented with subileus due to ascending colon cancer. Read More

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November 2016

Single-incision laparoscopy surgery: a systematic review.

Electron Physician 2016 Oct 25;8(10):3088-3095. Epub 2016 Oct 25.

M.D., Gynecologist, Fellowship of Infertility, Assistant Professor, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Background: Laparoscopic surgery is a modern surgical technique in which operations are performed far from their location through small incisions elsewhere in the body.

Objective: This systematic review is aimed to overview single-incision laparoscopy surgery.

Methods: This systematic review was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. Read More

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October 2016

Clinicopathological analysis and risk factors of advanced colorectal neoplasms incidentally detected by 18F-FDG PET-CT.

Eur J Gastroenterol Hepatol 2017 Apr;29(4):407-413

aDepartment of Internal Medicine, Division of Gastroenterology and Hepatology bDepartment of Nuclear Medicine, Yeungnam University College of Medicine, Daegu, Republic of Korea.

Background: As the clinical use of fluorine-18-fluorodeoxyglucose PET-computed tomography (F-FDG PET-CT) has increased, the incidental finding of F-FDG uptake with subsequent diagnosis of advanced neoplasm at colorectum has increased. The aim of this study is to analyze the characteristics and risk factors of advanced colorectal neoplasm incidentally detected by F-FDG PET-CT.

Patients And Methods: Patients who underwent colonoscopy because of an incidental finding of F-FDG uptake at the colorectum from January 2006 to January 2015 at Yeungnam University Hospital were reviewed retrospectively. Read More

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Total Transthoracic Approach Facilitates Laparoscopic Hepatic Resection in Patients with Significant Prior Abdominal Surgery.

Ann Surg Oncol 2017 May 22;24(5):1376-1377. Epub 2016 Nov 22.

Department of Surgical Oncology, Hepato-Pancreato-Biliary Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: While the oncologic safety of minimally invasive hepatectomy for colorectal liver metastases (CLM) has been demonstrated, lesions in the postero-superior segments may be challenging.1 3 For these lesions, a transthoracic approach may be particularly helpful, especially in patients with a hostile/reoperative abdomen or morbid obesity.4 5 PATIENT: A 43-year-old man with a body mass index of 36. Read More

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Total parietal peritonectomy with en bloc pelvic resection for advanced ovarian cancer with peritoneal carcinomatosis.

Gynecol Oncol 2016 Dec 13;143(3):688-689. Epub 2016 Oct 13.

Gynecologic Cancer Center, Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address:

Objective: The majority of advanced ovarian cancer patients have peritoneal carcinomatosis involving from the pelvis to upper abdomen, which is a major obstacle to optimal cytoreduction. Since total parietal peritonectomy was introduced for treating peritoneal carcinomatosis from colorectal cancer [3], similar surgical techniques including pelvic peritonectomy have been applied in advanced ovarian cancer with peritoneal carcinomatosis [1], and these can increase the rate of complete cytoreduction up to 60% [2]. However, there are few reports on total parietal peritonectomy for ovarian cancer patients. Read More

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December 2016