79,690 results match your criteria mental state

Fathers' Heightened Stress Responses to Recounting their NICU Experiences Months after Discharge: A Mixed Methods Pilot Study.

Am J Perinatol 2021 Jun 15. Epub 2021 Jun 15.

Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania.

Objective:  The acute and traumatic events associated with having a newborn who requires admission to the neonatal intensive care unit (NICU) may elicit long-term concerns for parents postdischarge. Cognitive processing of taxing events influences recurring stress responses, which can be inferred via biomarkers such as salivary cortisol (sCort) and skin conductance (SC). In addition, personal narratives provide an important insight into individual perceptions and coping strategies. Read More

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Greater adolescent tiredness is related to more emotional arousal during a hyperventilation task: An area under the curve approach.

J Adolesc 2021 Jun 12;90:45-52. Epub 2021 Jun 12.

University of Arkansas, USA. Electronic address:

Introduction: Approximately 36% of adolescents report sleep problems (Crowley et al., 2018). Understanding the relation between sleep and emotional experience is crucial in understanding the high incidence of mental health concerns during adolescence. Read More

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Early detection of cognitive decline in mild cognitive impairment and Alzheimer's disease with a novel eye tracking test.

J Neurol Sci 2021 Jun 3;427:117529. Epub 2021 Jun 3.

Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. Electronic address:

Due to an increasing number of dementia patients, the development of a rapid and sensitive method for cognitive assessment is awaited. Here, we examined the usefulness of a novel and short (3 min) eye tracking device to evaluate the cognitive function of normal control (NC, n = 52), mild cognitive impairment (MCI, n = 52), and Alzheimer's disease (AD, n = 70) subjects. Eye tracking total score declined significantly in MCI (**p < 0. Read More

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Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness.

Clin Nutr 2021 May 11;40(6):3868-3874. Epub 2021 May 11.

Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Nashville, TN, USA; Division of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University College of Medicine, Columbus OH, USA; Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address:

Background And Aims: Risk factors for poor outcomes after critical illness are incompletely understood. While nutritional risk is associated with mortality in critically ill patients, its association with disability, cognitive, and health-related quality of life is unclear in survivors of critical illness. This study's objective was to determine whether greater nutritional risk at ICU admission is associated with greater disability, worse cognition, and worse HRQOL at 3 and 12-month follow-up. Read More

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Describing the Mental Health State of Nurses in British Columbia: A Province-Wide Survey Study.

Healthc Policy 2021 May;16(4):31-45

Case and Contact Management, Pandemic Response, Island Health; Former Consultant, Former Executive Councillor of Occupational Health and Safety, British Columbia Nurses' Union, Burnaby, BC.

A cross-sectional province-wide survey study of 3,978 British Columbia (BC) nurses was conducted to explore the mental health state of the nursing workforce in BC. About one third of nurses reported depression and anxiety; about half reported symptoms of post-traumatic stress disorder and at least one third reported high levels of one or more dimensions of burnout. Mental health problems were about 1. Read More

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Effect of Virtual Reality Perspective-Taking on Related and Unrelated Contexts.

Cyberpsychol Behav Soc Netw 2021 Jun 14. Epub 2021 Jun 14.

Department of Communication, Stanford University, Stanford, California, USA.

Virtual reality perspective-taking (VRPT) experiences effectively increase both empathy and prosocial behaviors toward related social targets (e.g., cutting down a tree in virtual reality increases concern for the environment). Read More

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Peer-to-Peer Support and Changes in Health and Well-being in Older Adults Over Time.

JAMA Netw Open 2021 Jun 1;4(6):e2112441. Epub 2021 Jun 1.

Department of Medicine and Population Health, University of Texas at Austin Dell Medical School, Austin.

Importance: Literature on peer-to-peer (P2P) programs suggests they improve health and well-being of older adults. Analysis from a previous study showed P2P to be associated with higher rates of hospitalization and no significant differences in rates of emergency department or urgent care visits; however, it is not known whether measures of health and well-being varied by group over time.

Objective: To compare the association between receiving P2P support and secondary outcomes (ie, health status, quality of life, and depressive and anxiety symptoms) with receiving standard community services (SCS) over time. Read More

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Improving work-life balance among administrative officers in Catholic primary schools: Assessing the effect of a Christian religious rational emotive behavior therapy.

Medicine (Baltimore) 2021 Jun;100(24):e26361

Department of Educational Foundations, University of Nigeria, Enugu, Nigeria.

Objective: Work-life balance (WLB) is an essential precursor of workers' mental health. The theory of rational emotive behaviour therapy proposes that an imbalance in work and family life may result from people's dysfunctional perceptions of their work and other aspects of their personal life. Also, the constructive philosophies of rational emotive behavior therapy are said to be congruent with most religious belief systems of Christian clients. Read More

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Brain Exercising Games With Consumer-Grade Single-Channel Electroencephalogram Neurofeedback: Pre-Post Intervention Study.

JMIR Serious Games 2021 Jun 15;9(2):e26872. Epub 2021 Jun 15.

Department of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.

Background: The aging population is one of the major challenges affecting societies worldwide. As the proportion of older people grows dramatically, so does the number of age-related illnesses such as dementia-related illnesses. Preventive care should be emphasized as an effective tool to combat and manage this situation. Read More

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Preliminary Outcomes of an Ecological Momentary Intervention for Social Functioning in Schizophrenia: Pre-Post Study of the Motivation and Skills Support App.

JMIR Ment Health 2021 Jun 15;8(6):e27475. Epub 2021 Jun 15.

Department of Psychological & Brain Sciences, Boston University, Boston, MA, United States.

Background: People with schizophrenia and other serious mental illnesses often lack access to evidence-based interventions, particularly interventions that target meaningful recovery outcomes such as social functioning and quality of life. Mobile technologies, including smartphone apps, have the potential to provide scalable support that places elements of evidence-based interventions at the palm of patients' hands.

Objective: We aim to develop a smartphone app-called Motivation and Skills Support-to provide targeted social goal support (eg, making new friends and improving existing relationships) for people with schizophrenia enrolled in a stand-alone open trial. Read More

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Undergraduate medical education amid COVID-19: a qualitative analysis of enablers and barriers to acquiring competencies in distant learning using focus groups.

Med Educ Online 2021 Dec;26(1):1940765

Department of General Paediatrics, Neonatology, and Paediatric Cardiology, Düsseldorf University Department (UKD), Heinrich-Heine-University, Düsseldorf, Germany.

Due to comprehensive social distancing measures related to the COVID-19 pandemic, medical faculties worldwide have made a virtue of necessity in resorting to online teaching. Medical faculties grapple with how to convey clinical competencies to students in this context. There is a need for research not only to map but also to explain the effect of these secondary measures on students' learning and mental wellbeing. Read More

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December 2021

The temporal representation of experience in subjective mood.

Elife 2021 Jun 15;10. Epub 2021 Jun 15.

Emotion and Development Branch, National Institutes of Health / National Institute of Mental Health, Bethesda, United States.

Humans refer to their mood state regularly in day-to-day as well as clinical interactions. Theoretical accounts suggest that when reporting on our mood we integrate over the history of our experiences; yet, the temporal structure of this integration remains unexamined. Here we use a computational approach to quantitatively answer this question and show that early events exert a stronger influence on reported mood compared to recent events. Read More

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Evidence Based Approach to Capacity Assessment for Hospitalized Patients.

CNS Spectr 2021 Apr;26(2):150

Creighton University, Omaha, NE, USA.

Medical decision-making capacity (MDMC) is inherent to the legal and ethical principles of respect for autonomy and is an essential element of informed consent. Qualitative and quantitative evidence to support a final decision of capacity should be the gold standard. General hospital policies and state laws mandate that a licensed provider make the final determination of capacity, but they do not specifically mandate who is responsible for those assessments. Read More

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Implementation of NAVIGATE Coordinated Specialty Care for First Episode Psychosis: the Michigan Experience.

CNS Spectr 2021 Apr;26(2):177-178

The Zucker Hillside Hospital, Glen Oaks, NY, USA.

Study Objectives: Coordinated specialty care (CSC) is widely accepted as an evidence-based treatment for first episode psychosis (FEP). The NAVIGATE intervention from the Recovery After an Initial Schizophrenia Episode Early Treatment Program (RAISE-ETP) study is a CSC intervention which offers a suite of evidence-based treatments shown to improve engagement and clinical outcomes, especially in those with shorter duration of untreated psychosis (DUP). Coincident with the publication of this study, legislation was passed by the United States Congress in 2014-15 to fund CSC for FEP via a Substance Abuse and Mental Health Services Administration (SAMHSA) block grant set-aside for each state. Read More

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Dietary, physical exercises and mental stress in a Chinese population: a cross-sectional study.

BMC Public Health 2021 Jun 14;21(1):1138. Epub 2021 Jun 14.

Department of Health Management, School of Public Health, Center for Global Health, Nanjing Medical University, Nanjing, 211166, China.

Background: Mental health is affected by both genetic and environmental factors. However, previous studies have showed conflict findings about the role of lifestyle and little is known about the situation of the Chinese population. The purpose of this study was to explore the relationship between the frequency of food consumption, physical exercise condition and mental health, as well as factors related to mental stress in Chinese. Read More

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Inter-rater reliability of subthreshold psychotic symptoms in individuals with 22q11.2 deletion syndrome.

J Neurodev Disord 2021 Jun 14;13(1):23. Epub 2021 Jun 14.

The Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.

Background: Pathways leading to psychosis in 22q11.2 deletion syndrome (22q11.2DS) have been the focus of intensive research during the last two decades. Read More

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HIV Testing and Counseling at U.S. Substance Use Treatment Facilities: A Missed Opportunity for Early Identification.

Psychiatr Serv 2021 Jun 15:appips202000524. Epub 2021 Jun 15.

Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences (Riano, Bazazi, Mangurian), School of Medicine (Borowsky, Arnold), Center for AIDS Prevention Studies (Arnold), and Department of Epidemiology and Biostatistics (Vittinghoff, Mangurian), University of California, San Francisco, San Francisco; New York State Psychiatric Institute, New York City (Olfson, Cournos); Department of Psychiatry, Vagelos College of Physicians and Surgeons (Olfson), and Mailman School of Public Health (Cournos), Columbia University, New York City; Institute for Health, Health Care Policy and Aging Research (Walkup) and Center for Health Services Research (Crystal), Rutgers University, New Brunswick, New Jersey; Kaiser Family Foundation, HIV Policy, Washington, D.C. (Dawson).

Objective: The objective of this study was to determine the availability and national distribution of HIV testing and counseling at substance use treatment facilities in the United States.

Methods: Analyses of data from the 2018 National Survey of Substance Abuse Treatment Services assessed HIV testing and counseling availability in U.S. Read More

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Scale-Up Study Protocol of the Implementation of a Mobile Health SBIRT Approach for Alcohol Use Reduction in Mozambique.

Psychiatr Serv 2021 Jun 15:appips202000086. Epub 2021 Jun 15.

Department of Psychiatry and Mental Health, Psychiatric Hospital of Nampula, Mozambique (Suleman, Feliciano, Anube); Department of Psychiatry, Columbia University, New York City (Mootz, Nicholson, Wall, Stockton, Wainberg); New York State Psychiatric Institute, New York City (Mootz, Wall, Stockton, Wainberg); Department of Public Health Sciences, University of Connecticut School of Medicine, Farmington (O'Grady); Center for Mental Health, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia (Mandell); Department of Mental Health, Ministry of Health, Mozambique (Teodoro, Novela, Mocumbi, Gouveia).

Background: Hazardous drinking imposes a major public health burden worldwide, especially in low-income countries such as Mozambique. Implementation of the Screening, Brief Intervention, Referral to Treatment (SBIRT) approach to address problem drinking is recommended. However, evidence regarding the best strategies to implement SBIRT at scale is needed. Read More

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Heritable consequences of paternal nicotine exposure: From phenomena to mechanisms.

Biol Reprod 2021 Jun 14. Epub 2021 Jun 14.

Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306, USA.

Our understanding of the interactions between genetic and environmental factors in shaping behavioral phenotypes has expanded to include environment-induced epigenetic modifications and the intriguing possibility of their association with heritable behavioral phenotypes. The molecular basis of heritability of phenotypes arising from environment-induced epigenetic modifications is not well defined yet. However, phenomenological evidence in favor of it is accumulating rapidly. Read More

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Efficacy and safety of treatment modalities across EGFR selected/unselected populations with non-small cell lung cancer and brain metastases: A systematic review and Bayesian network meta-analysis.

Lung Cancer 2021 Feb 27;158:74-84. Epub 2021 Feb 27.

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China; State Key Laboratory of Molecular Oncology, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. Electronic address:

Objective: To compare the efficacy and safety of treatment modalities across different populations with non-small cell lung cancer and brain metastases.

Methods: A comprehensive search for randomized controlled trials was conducted in databases including PubMed, Embase, the Cochrane library, the ClinicalTrials.gov, and major international conferences. Read More

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February 2021

Abnormality of subcortical volume and resting functional connectivity in adolescents with early-onset and prodromal schizophrenia.

J Psychiatr Res 2021 Jun 4;140:282-288. Epub 2021 Jun 4.

Shanxi Key Laboratory of Artificial Intelligence Assisted Diagnosis and Treatment for Mental Disorder, First Hospital of Shanxi Medical University, Taiyuan, China; Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China; Department of Mental Health, Shanxi Medical University, Taiyuan, China. Electronic address:

Objective: Studies have found that there may be qualitative changes in brain structure and function in adolescents with early-onset schizophrenia (EOS) and prodromal schizophrenia (PDS). However, the abnormal brain structure and function of adolescents with EOS and PDS have received little attention, and their underlying neural mechanisms are still unknown.

Methods: In this study, structural and resting-state functional magnetic resonance imaging (fMRI) were used to compare the subcortical volume and functional connectivity (FC) among EOS, PDS, and a control group. Read More

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App-based data collection, mental imagery, and naming performance in adults with aphasia.

Complement Ther Clin Pract 2021 May 29;44:101422. Epub 2021 May 29.

Department of Communication Sciences and Disorders, Georgia State University, United States; Department of Learning Sciences, Georgia State University, United States. Electronic address:

Background And Purpose: Naming impairments are often found in aphasia. Combining mHealth technology with mental imagery may offer new insights into novel approaches to naming interventions in persons with aphasia. The aims of this study are to (1) explore whether mental imagery can improve performance during a naming task in adults with aphasia; and, (2) demonstrate the use of app-based data collection for research in aphasia rehabilitation through utilization of an app designed specifically for this study. Read More

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Loss of cGMP-dependent protein kinase II alters ultrasonic vocalizations in mice, a model for speech impairment in human microdeletion 4q21 syndrome.

Neurosci Lett 2021 Jun 11:136048. Epub 2021 Jun 11.

Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA; Molecular, Cellular and Integrative Neurosciences Program, Colorado State University, Fort Collins, CO, 80523, USA. Electronic address:

Chromosome 4q21 microdeletion leads to a human syndrome that exhibits restricted growth, facial dysmorphisms, mental retardation, and absent or delayed speech. One of the key genes in the affected region of the chromosome is PRKG2, which encodes cGMP-dependent protein kinase II (cGKII). Mice lacking cGKII exhibit restricted growth and deficits in learning and memory, as seen in the human syndrome. Read More

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Bovine extracellular vesicles contaminate human extracellular vesicles produced in cell culture conditioned medium when 'exosome-depleted serum' is utilised.

Arch Biochem Biophys 2021 Jun 11;708:108963. Epub 2021 Jun 11.

Deakin University, School of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical Translation, Geelong, Victoria, 3216, Australia; Shanghai OneTar-Deakin Joint Laboratory of Personalized Precision Medicine, Shanghai, 201203, China. Electronic address:

Extracellular vesicles (EVs) are important intercellular communication messengers. Half of the published studies in the field are in vitro cell culture based in which bovine serum in various concentrations and forms is used to facilitate the production of extracellular vesicles. 'Exosome depleted serum' is the type of bovine serum most widely used in the production of human EVs. Read More

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Left Lateralization of Neonatal Caudate Microstructure Affects Emerging Language Development at 24 months.

Eur J Neurosci 2021 Jun 14. Epub 2021 Jun 14.

Singapore Institute for Clinical Sciences (SICS), A*STAR Research Entities (ARES), Singapore.

The complex interaction between brain and behavior in language disorder is well established. Yet to date, the imaging literature in the language disorder field has continued to pursue heterogeneous and relatively small clinical cross-sectional samples, with emphasis on cortical structures and volumetric analyses of subcortical brain structures. In our current work, we aimed to go beyond this state of knowledge to focus on the microstructural features of subcortical brain structures (specifically the caudate nucleus) in a large cohort of neonates, and study its association with emerging language skills at 24 months. Read More

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A 25-Year Review of Nighttime Fears in Children: Past, Present, and Future.

Clin Child Fam Psychol Rev 2021 Jun 14. Epub 2021 Jun 14.

Department of Psychology, Child Study Center, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24060, USA.

Nighttime fears in children are common, interfere with daily functioning, and result in considerable disruption in the family. The aim of the present review was to examine empirical literature from the past 25 years that investigated the assessment of nighttime fears in young children and the efficacy and effectiveness of psychosocial treatments for children's nighttime fears. The last review of this literature was in 1997 and examined studies conducted in and prior to 1995 (King et al. Read More

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