J Acquir Immune Defic Syndr 2021 May 28. Epub 2021 May 28.
Department of Medicine, Section of Geriatric Medicine, University of Calgary, Calgary, Alberta, Canada Southern Alberta Clinic, Calgary, Alberta, Canada Department of Medicine, University of Calgary, Calgary, Alberta, Canada Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, Canada Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada Departments of Neurology and Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD.
Background: The co-occurrence of frailty and cognitive impairment in older (50+) persons with HIV (PWH) is common and increases the risk of poor outcomes. In HIV clinics, the most commonly used frailty measures are the frailty phenotype (FP), which requires measuring grip strength and gait speed to implement, and the frailty index (FI) based on comprehensive health data collected on patients. We examined construct and criterion-related validity (as it predicts cognition) of the clinical frailty scale (CFS), a less resource-intensive approach for assessing frailty, in relation to these more commonly used frailty assessments (FP, FI). Read More