Int Arch Occup Environ Health 2012 Jul 7;85(5):505-15. Epub 2011 Sep 7.
Department of Occupational and Environmental Health, University of Iowa, University of Iowa Research Park, 140 IREH, Iowa City, IA 52242-5000, USA.
Purpose: While acute pesticide poisoning can be associated with persistent adverse central nervous system (CNS) effects, little is known about the effect of one or more episodic and unusually high pesticide exposure events (HPEE) that typically do not result in acute poisoning. The objective of this investigation was to examine the association between ever having an HPEE and CNS function among licensed pesticide applicators enrolled in the Agricultural Health Study (AHS).
Methods: In 2006-2008, 693 male participants with no history of a physician-diagnosed pesticide poisoning completed nine neurobehavioral tests to assess memory, motor speed, sustained attention, verbal learning, and visual scanning and processing. Read More