6,609 results match your criteria melbourne 2010

Ambient Air Pollution and Stillbirths Risk in Sydney, Australia.

Toxics 2021 Aug 31;9(9). Epub 2021 Aug 31.

Centre for Air Pollution, Energy and Health Research (CAR), Glebe 2037, Australia.

We aimed to determine the associations between ambient air pollution, specifically particulate matter less than or equal to 10 microns and 2.5 microns (PM and PM respectively) and ozone (O), and stillbirths. We analysed all singleton births between 20-42 weeks gestation in metropolitan Sydney, Australia, from 1997 to 2012. Read More

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Ovarian Cancer Incidence and Death in Average-Risk Women Undergoing Bilateral Salpingo-Oophorectomy at Benign Hysterectomy.

Am J Obstet Gynecol 2021 Sep 23. Epub 2021 Sep 23.

Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada; ICES (formerly the Institute for Clinical Evaluative Sciences), Toronto, ON, Canada; Department of Surgery, University of Toronto, Toronto, ON, Canada; Melbourne School of Population and Global Health, University of Melbourne, Melbourne VIC, Australia. Electronic address:

Background: Opportunistic bilateral salpingo-oophorectomy (BSO) is often offered to patients undergoing benign hysterectomy to prevent ovarian cancer, but the magnitude of risk reduction obtained with BSO in this population remains unclear, and must be weighed against potential risks of ovarian hormone deficiency.

Objective: To quantify the relative and absolute risk reduction in ovarian cancer incidence and death associated with BSO at the time of benign hysterectomy.

Study Design: We performed a population-based cohort study of all adult women (>20 years) undergoing benign hysterectomy from 1996 to 2010 in Ontario, Canada. Read More

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September 2021

Trends in Diagnosis and Treatment of Metastatic Cancer in the United States.

Am J Clin Oncol 2021 Sep 27. Epub 2021 Sep 27.

Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY Departments of Family and Community Medicine Public Health Sciences Surgery, Penn State College of Medicine Departments of Biochemistry and Molecular Biology Radiation Oncology, Penn State Cancer Institute, Hershey, PA Section of Surgical Oncology, Baptist MD Anderson Cancer Center Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL Department of Radiation Oncology, Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Vic., Australia Odette Cancer Centre-Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Objectives: Metastatic cancer has historically been considered fatal; however, there is a paucity of evidence characterizing the epidemiology of incidence, treatment, and outcomes in these patients.

Materials And Methods: Incidence rates, annual percent change (APC), descriptive epidemiological statistics, and odds ratios for survival were calculated using registry data from the Surveillance, Epidemiology, and End Results (SEER) and the National Cancer Database (NCDB), 1998 to 2015.

Results: There were a total of 1,055,860 patients with metastatic cancer. Read More

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September 2021

The same but different: a comparison of Staphylococcus aureus bloodstream infections in metropolitan and non-metropolitan hospitals (2010-2020).

Intern Med J 2021 Sep 22. Epub 2021 Sep 22.

Victorian Healthcare Associated Infection Surveillance System (VICNISS) Coordinating Centre, Melbourne, VIC, 3000.

Background: Variation of infection rates between hospitals must be identified; differences may highlight opportunities for quality improvement in healthcare delivery to specific hospitals groups.

Aim: To analyse burden, time-trends and risks of healthcare associated (HA) Staphylococcus aureus bloodstream infections (SABSI) in patients admitted to Victorian metropolitan and non-metropolitan public acute care hospitals.

Methods: SABSI surveillance data submitted between 1 July 2010 and 30 June 2020 by all 118 Victorian public acute care hospitals were analysed. Read More

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September 2021

Poor Reporting of Exercise Interventions for Hamstring Strain Injury Rehabilitation: A Scoping Review of Reporting Quality and Content in Contemporary Applied Research.

J Orthop Sports Phys Ther 2021 Sep 21:1-32. Epub 2021 Sep 21.

School of Behavioural and Health Sciences, Australian Catholic University, Melbourne, VIC, Australia.

Objective: To review the quality of reporting and identify the content of exercise interventions prescribed for hamstring strain injury (HSI) rehabilitation in the scientific literature since 2010.

Design: Scoping review.

Literature Search: We searched the bibliometric databases Web of Science, CINAHL, SPORTDiscus, Scopus, Cochrane Library, MEDLINE and EMBASE. Read More

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September 2021

Trigger point injection for post-mastectomy pain: a simple intervention with high rate of long-term relief.

NPJ Breast Cancer 2021 Sep 17;7(1):123. Epub 2021 Sep 17.

Department of Surgery, University of California, San Francisco, San Francisco, CA, USA.

Post-mastectomy pain syndrome (PMPS) is a common and often debilitating condition. The syndrome is defined by chest wall pain unresponsive to standard pain medications and the presence of exquisite point tenderness along the inframammary fold at the site of the T4 and T5 cutaneous intercostal nerve branches as they exit from the chest wall. Pressure at the site triggers and reproduces the patient's spontaneous or motion-evoked pain. Read More

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September 2021

Predicting regression of cervical intraepithelial neoplasia grade 2 in women under 25 years.

Am J Obstet Gynecol 2021 Sep 14. Epub 2021 Sep 14.

National Women's Health, Auckland District Health Board, Auckland, New Zealand; Department of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.

Background: A number of retrospective and prospective studies have documented significant rates of regression in cervical intraepithelial neoplasia grade 2 (CIN2) lesions in young women. The initial observational management of CIN2 is increasingly accepted as appropriate for women under 25 years of age with screen detected abnormalities, and is included in a number of clinical guidelines. However, there has been a paucity of large prospective studies of observational management with strict inclusion criteria. Read More

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September 2021

Trends in management of hip and knee osteoarthritis in general practice in Australia over an 11-year window: a nationwide cross-sectional survey.

Lancet Reg Health West Pac 2021 Jul 9;12:100187. Epub 2021 Jun 9.

Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Parkville, Victoria, 3010, Australia.

Background: We aimed to describe trends in knee and hip OA management by general medical practitioners (GPs) in Australia.

Methods: We analysed cross-sectional survey data from the Bettering the Evaluation and Care of Health (BEACH) program (1,000 randomly-selected GPs annually recording 100 consecutive patient encounters) over two periods: Period one April 1, 2005-March 31, 2010 and period two April 1, 2010-March 31, 2016. This included data from 10,738 GPs and 1,073,800 patient encounters with 6,565 GPs and 9,196 patient encounters for hip/knee OA. Read More

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Long-term Blood Pressure Variability and Kidney Function in Participants of the ASPREE Trial.

Am J Hypertens 2021 Sep 14. Epub 2021 Sep 14.

School of Public Health and Preventive Medicine, Monash University; Melbourne, VIC, Australia.

Background: Whether long-term blood pressure variability (BPV) predicts kidney function decline in generally healthy older adults is unknown. We investigated this association in ASPirin in Reducing Events in the Elderly (ASPREE) trial participants.

Methods: Between 2010-2014, Australian and US individuals aged ≥70 years ( ≥65 if US minority) were recruited and followed with annual study visits for a median of 4. Read More

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September 2021

Associations of ophthalmic and systemic conditions with incident dementia in the UK Biobank.

Br J Ophthalmol 2021 Sep 13. Epub 2021 Sep 13.

Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, People's Republic of China

Aims: To examine independent and interactive associations of ophthalmic and systemic conditions with incident dementia.

Methods: Our analysis included 12 364 adults aged 55-73 years from the UK Biobank cohort. Participants were assessed between 2006 and 2010 at baseline and were followed up until the early of 2021. Read More

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September 2021

Violence-related morbidity among people released from prison in Australia: A data linkage study.

Drug Alcohol Rev 2021 Sep 12. Epub 2021 Sep 12.

Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.

Introduction: People released from prison have an increased risk of morbidity, including from nonfatal violence. We examined the incidence and predictors of violence-related morbidity after release from prison and investigated whether there are differences according to sex and Indigenous status.

Methods: Baseline data were collected from 1325 people within 6 weeks of release from prisons in Queensland, Australia, between 1 August 2008 and 31 July 2010. Read More

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September 2021

The efficacy, challenges, and facilitators of telemedicine in post-treatment cancer survivorship care: an overview of systematic reviews.

Ann Oncol 2021 Sep 9. Epub 2021 Sep 9.

School of Pharmacy & Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA.

Background: Telemedicine services have been increasingly used to facilitate post-treatment cancer survivorship care, including improving access; monitoring health status, health behaviors, and symptom management; enhancing information exchange; and mitigating the costs of care delivery, especially since the COVID-19 pandemic. To inform guidance for the use of telemedicine in the post-COVID era, the aim of this overview of systematic reviews was to evaluate the efficacy of, and survivor engagement in, telemedicine interventions in the post-treatment survivorship phase, and to consider implementation barriers and facilitators.

Methods: PubMed, Cochrane CENTRAL, CINAHL, Embase, and Web of Science databases were searched. Read More

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September 2021

Planned granulocyte-colony stimulating factor adversely impacts survival after allogeneic hematopoietic cell transplantation performed with Thymoglobulin for myeloid malignancy.

Transplant Cell Ther 2021 Sep 7. Epub 2021 Sep 7.

Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: The in vivo depletion of recipient and donor T-lymphocytes using anti-thymocyte globulin (ATG) is widely adopted in allogeneic hematopoietic stem cell transplantation (HCT) to reduce the incidence of both graft failure and graft versus host disease (GVHD). However excess toxicity to donor lymphocytes may hamper immune reconstitution, compromising anti-tumour effects and increasing infection. Granulocyte-colony stimulating factor (G-CSF) administered early after HCT may increase ATG-mediated lympho-toxicity. Read More

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September 2021

Pityriasis rubra pilaris treatment options: A retrospective case series from a tertiary hospital.

Dermatol Ther 2021 Sep 10:e15128. Epub 2021 Sep 10.

Department of Dermatology, St Vincent's Hospital Melbourne, Fitzroy, Australia.

Pityriasis rubra pilaris (PRP) is a group of uncommon chronic inflammatory skin conditions with unclear pathophysiology and etiology. To date there is limited published literature and no clinical guidelines for the management of PRP. Infliximab, alone or in combination, is the most widely published successful treatment for adults and etanercept for pediatric populations. Read More

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September 2021

Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx Digital Spatial Profiler.

Cancers (Basel) 2021 Sep 4;13(17). Epub 2021 Sep 4.

Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.

Breast cancer is a heterogenous disease with variability in tumor cells and in the surrounding tumor microenvironment (TME). Understanding the molecular diversity in breast cancer is critical for improving prediction of therapeutic response and prognostication. High-plex spatial profiling of tumors enables characterization of heterogeneity in the breast TME, which can holistically illuminate the biology of tumor growth, dissemination and, ultimately, response to therapy. Read More

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September 2021

What is "usual care" in the rehabilitation of upper limb sensory loss after stroke? Results from a national audit and knowledge translation study.

Disabil Rehabil 2021 Sep 9:1-9. Epub 2021 Sep 9.

Occupational Therapy, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia.

Purpose: To characterise the assessments and treatments that comprise "usual care" for stroke patients with somatosensory loss, and whether usual care has changed over time.

Materials And Methods: Comparison of cross-sectional, observational data from (1) Stroke Foundation National Audit of Acute (2007-2019) and Rehabilitation (2010-2018) Stroke Services and (2) the SENSe Implement multi-site knowledge translation study with occupational therapists and physiotherapists ( = 115). Descriptive statistics, random effects logistic regression, and content analysis were used. Read More

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September 2021

ConCerv: a prospective trial of conservative surgery for low-risk early-stage cervical cancer.

Int J Gynecol Cancer 2021 Sep 7. Epub 2021 Sep 7.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Objective: The objective of the ConCerv Trial was to prospectively evaluate the feasibility of conservative surgery in women with early-stage, low-risk cervical cancer.

Methods: From April 2010 to March 2019, a prospective, single-arm, multicenter study evaluated conservative surgery in participants from 16 sites in nine countries. Eligibility criteria included: (1) FIGO 2009 stage IA2-IB1 cervical carcinoma; (2) squamous cell (any grade) or adenocarcinoma (grade 1 or 2 only) histology; (3) tumor size 2 cm; (4) no lymphovascular space invasion; (5) depth of invasion 10 mm; (6) negative imaging for metastatic disease; and (7) negative conization margins. Read More

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September 2021

A 10-year retrospective review of management and outcomes of pseudoaneurysms at a tertiary referral centre.

J Med Imaging Radiat Oncol 2021 Sep 7. Epub 2021 Sep 7.

Department of Radiology, Alfred Hospital, Melbourne, Victoria, Australia.

Introduction: Pseudoaneurysms are uncommon but potentially life-threatening. Treatment may involve a variety of interventions including observation, manual compression, ultrasound-guided thrombin injection and a variety of endovascular and surgical techniques. Current treatments are largely based on observational data and there is no consensus on management. Read More

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September 2021

Response of canine thyroid carcinomas to radioiodine.

Vet Comp Oncol 2021 Sep 2. Epub 2021 Sep 2.

Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, Victoria, Australia.

Radioactive iodine ( I) has previously been reported to prolong survival in dogs with thyroid carcinoma. This study aimed to describe tumour response and progression-free interval (PFI) in dogs with thyroid carcinomas treated with I. Secondary aims were to describe overall survival time (OST) and prognostic factors. Read More

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September 2021

Quality of stroke guidelines in low- and middle-income countries: a systematic review.

Bull World Health Organ 2021 Sep 29;99(9):640-652E. Epub 2021 Jun 29.

Department of Medicine, University College Hospital, Ibadan, Nigeria.

Objective: To identify gaps in national stroke guidelines that could be bridged to enhance the quality of stroke care services in low- and middle-income countries.

Methods: We systematically searched medical databases and websites of medical societies and contacted international organizations. Country-specific guidelines on care and control of stroke in any language published from 2010 to 2020 were eligible for inclusion. Read More

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September 2021

Novel Therapies for Kidney Disease in People with Diabetes.

J Clin Endocrinol Metab 2021 Aug 30. Epub 2021 Aug 30.

Department of Medicine, the University of Melbourne, Parkville, Victoria, Australia.

Aim: The increasing burden of diabetic kidney disease (DKD) has led to the discovery of novel therapies. This review aims to summarise the results of recent clinical trials that test the efficacy of potential therapies for DKD.

Methods: A systematised narrative review was performed utilising PubMed, Embase (Ovid), CINAHL and Cochrane databases (January 2010-January 2021). Read More

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Tobacco control policies and smoking cessation treatment utilization: A moderated mediation analysis.

PLoS One 2021 30;16(8):e0241512. Epub 2021 Aug 30.

Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.

Background: Tobacco policies, including clean indoor air laws and cigarette taxes, increase smoking cessation in part by stimulating the use of cessation treatments. We explored whether the associations between tobacco policies and treatment use varies across sociodemographic groups.

Methods: We used data from 62,165 U. Read More

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Fungal Planet description sheets: 1112-1181.

Persoonia 2020 Dec 19;45:251-409. Epub 2020 Dec 19.

Departamento de Biología Vegetal (Botánica), Facultad de Biología, Universidad de Murcia, 30100 Murcia, Spain.

Novel species of fungi described in this study include those from various countries as follows: , on soil, on leaves of on leaves of on leaves of sp., on soil, (incl. gen. Read More

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December 2020

Disposition intentions of elective egg freezers toward their surplus frozen oocytes: a systematic review and meta-analysis.

Fertil Steril 2021 Aug 24. Epub 2021 Aug 24.

Department of Obstetrics and Gynecology, University of Melbourne, Level 7, Royal Women's Hospital, Victoria, Australia.

Objective: To examine the disposition outcomes and disposition intentions of elective egg freezers (EEFs) toward their surplus frozen oocytes and the psychosocial determinants underlying these.

Design: A systematic review and meta-analysis.

Setting: Not applicable. Read More

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Female Gender Is Associated with Higher Susceptibility of Weight Induced Arterial Stiffening and Rise in Blood Pressure.

J Clin Med 2021 Aug 6;10(16). Epub 2021 Aug 6.

Dobney Hypertension Centre, School of Medicine-Royal Perth Hospital Research Foundation, University of Western Australia, Perth, WA 6000, Australia.

Arterial stiffness is an important predictor of cardiovascular events, independent of traditional risk factors. Stiffening of arteries, though an adaptive process to hemodynamic load, results in substantial increase in the pulsatile hemodynamic forces that detrimentally affects the microcirculation perfusing the vital organs such as the brain, heart and kidneys. Studies have proposed that arterial stiffness precedes and may contribute to the development of hypertension in individuals with obesity. Read More

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The predictive value of PET/CT for distant recurrences in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy.

J Med Imaging Radiat Oncol 2021 Aug 25. Epub 2021 Aug 25.

Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

Introduction: It is well recognized that pathological complete response (pCR) for locally advanced rectal cancer after neoadjuvant chemoradiotherapy (CRT) confers a positive survival advantage. Despite this, a small proportion of patients can develop distant recurrence, and these are the patients that will likely benefit from adjuvant therapy. This study aims to investigate the role of PET/CT as a functional imaging to stratify patients according to their risk of distant recurrence. Read More

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Predicting successful sperm retrieval in transfeminine adolescents after testicular biopsy.

J Assist Reprod Genet 2021 Aug 23. Epub 2021 Aug 23.

Murdoch Children's Research Institute, Parkville, VIC, Australia.

Purpose: Increasing numbers of transgender adolescents are receiving gender-affirming treatments (GAT). Given GAT can impair reproductive function, clinical guidelines advise prior counselling regarding fertility preservation (FP). For transgender adults assigned male at birth, FP is usually achieved via a masturbatory sample and sperm cryopreservation. Read More

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Preparing for Future Adversities: Lessons From the COVID-19 Pandemic in Australia for Promoting Relational Resilience in Families.

Front Psychiatry 2021 4;12:717811. Epub 2021 Aug 4.

Centre for Social and Early Emotional Development, School of Psychology, Faculty of Health, Deakin University, Geelong, VIC, Australia.

The COVID-19 pandemic has placed considerable pressure on families, testing the quality of relationships and the strength of social support within and beyond the family network. However, little is known about the pre-pandemic factors that predict family relational resilience and social functioning during times of natural disaster or global crisis. Here we use data from one of Australia's longest running studies of social and emotional development to examine the nature and timing of possible relational and social support intervention aimed at preparing families for future adversities. Read More

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Adherence to evidence-based processes of care reduces one-year mortality after aneurysmal subarachnoid hemorrhage (aSAH).

J Neurol Sci 2021 Sep 11;428:117613. Epub 2021 Aug 11.

Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia; Monash University, Clayton, Victoria, Australia. Electronic address:

Background: There is limited research on the provision of evidence-based care and its association with outcomes after aneurysmal subarachnoid hemorrhage (aSAH).

Aims: We examined adherence to evidence-based care after aSAH and associations with survival and discharge destination. Also, factors associated with evidence-based care including age, sex, Charlson comorbidity index, severity scores, and delayed cerebral ischemia and infarction were examined for association with survival and discharge destination. Read More

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September 2021

The impact of scaling up access to treatment and imaging modalities on global disparities in breast cancer survival: a simulation-based analysis.

Lancet Oncol 2021 09 17;22(9):1301-1311. Epub 2021 Aug 17.

Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.

Background: Female breast cancer is the most commonly diagnosed cancer in the world, with wide variations in reported survival by country. Women in low-income and middle-income countries (LMICs) in particular face several barriers to breast cancer services, including diagnostics and treatment. We aimed to estimate the potential impact of scaling up the availability of treatment and imaging modalities on breast cancer survival globally, together with improvements in quality of care. Read More

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September 2021