Semin Cancer Biol 2021 May 4. Epub 2021 May 4.
School of Pharmaceutical Sciences, Tsinghua University, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Beijing, 100082, China; Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing, 100084, China; Beijing Advanced Innovation, Center for Structural Biology, Tsinghua University, Beijing, China. Electronic address:
Cancer therapeutic strategies include surgeries, radiotherapy, chemotherapy, targeted therapy and immunotherapies. However, current cancer treatment still faces challenges such as postoperative residuals, postoperative recurrence, chemoradiotherapy resistance and lack of drugs with high specificity, due to the complexity of the cancer environment. Extracellular vesicles (EVs) are lipid-capsuled membrane vesicles secreted from cells, communicating vital messages between cells and regarding function in tumorigenesis and metastasis. Read More