1,984,829 results match your criteria medical patients


UKRAINE'S INTERNATIONAL LIABILITIES ON INITIATION OF MEASURES FOR PUBLIC HEALTH PROTECTION AND THE ROLE OF LOCAL AUTHORITIES IN IMPLEMENTATION OF HEALTH CARE POLICY.

Georgian Med News 2021 Mar(312):163-168

4Lviv University of Trade and Economics, Ukraine.

The article examines the international obligations of Ukraine to implement measures to protect public health and the role of local governments in implementation of health policy. Emphasis is placed on Ukraine's implementation of the Sustainable Development Goals being a member of the UN, the Association Agreement between Ukraine and the EU, and the commitment to develop cooperation in the field of health care undertaken by Ukraine, radical health care reform and decentralization reform in Ukraine. The purpose of the article is to determine the role of local governments in implementation of health policy in the context of decentralization reform and the second stage of health care reform in Ukraine, to identify shortcomings in Ukrainian legislation and the practice that lead to violations of regional communities residents' rights for health care and medical aid, as well as violations of the rights of medical personnel for labor. Read More

View Article and Full-Text PDF

DISTRIBUTION OF STEM CELLS IN DIFFERENT THYROID LESIONS IN PATIENTS OF REPRODUCTIVE, MENOPAUSAL AND POST-MENOPAUSAL AGE.

Georgian Med News 2021 Mar(312):92-99

Tbilisi State Medical University.

Different studies indicate that cancer stem cells (CSCs) play an important role in the progression and therapy resistance in different cancer types. The aim of our study was to analyse the distribution of CSCs in different thyroid lesions, in reproductive, menopausal and post-menopausal women. Study included altogether 200 formalin-fixed and paraffin-embedded tissue material, with the diagnosis of NIFTP, Hashimoto's thyroiditis, papillary thyroid carcinoma (PTC) and PTC and Hashimoto's thyroiditis co-occurred cases. Read More

View Article and Full-Text PDF

COMORBIDITY OF TYPE 1 DIABETES MELLITUS WITH OTHER CHRONIC PATHOLOGY IN CHILDREN.

Georgian Med News 2021 Mar(312):78-82

1V. Karazin Kharkiv National University, School of Medicine; 2SI "Institute of Health of Children and Adolescents of the National Academy of Medical Sciences of Ukraine", Kharkiv, Ukraine.

In this study was to investigate the сoexistence of diabetes mellitus type 1 with other chronic pathology in children and adolescents and their impact on the course of diabetes mellitus type 1 (DM1). The 88 children from 3 to 17 years who had DM1 were observed. The study was conducted by survey with the aim of finding risk factors and associated comorbidties with a questionnaire-based, objective-subjective study. Read More

View Article and Full-Text PDF

INFLUENCE OF URSODEOXYCHOLIC ACID ON THE CHOLECYSTOKININ LEVELS IN PATIENTS WITH GASTRO-ESOPHAGEAL REFLUX DISEASE AND TYPE 2 DIABETES MELLITUS.

Georgian Med News 2021 Mar(312):67-71

State Higher Educational Institution «Uzhhorod National University», Medical Faculty, Ukraine.

Of particular interest is the study of the peculiarities of clinical findings and diagnostics of gastroesophageal reflux disease (GERD) in patients with diabetes mellitus (DM). The aim of the research - to study the dynamics of cholecystokinin (CCK) level on the background of complex therapy using the ursodeoxycholic acid (UDCA) drug in patients with GERD with type 2 DM. 68 patients with combination of type 2 DM and GERD were examined. Read More

View Article and Full-Text PDF

[INFLUENCE OF COMBINED ERADICATION AND PROKINETIC THERAPY ON CLINICAL MANIFESTATIONS, PSYCHOLOGICAL STATUS AND QUALITY OF LIFE OF PATIENTS WITH FUNCTIONAL DYSPEPSIA - POSTPRANDIAL DISTRESS SYNDROME: RANDOMIZED PROSPECTIVE STUDY].

Georgian Med News 2021 Mar(312):61-67

1Bogomolets National Medical University, Kyiv; Ukraine.

Functional dyspepsia - postprandial distress-syndrome (FD-PDS) is one of the most common reasons for seeking medical attention of general practitioners, internists and gastroenterologists worldwide. Standard approaches to the treatment of patients with postprandial distress syndrome are only effective in small amount of cases. Aim of the study - comparative assessment of the effectiveness of combined eradication and prokinetic therapy and eradication therapy only in the treatment of FD-PDS by studying their effect on the clinical manifestations of the disease, patients' psychological status and quality of life. Read More

View Article and Full-Text PDF

CLINICAL, PHARMACOTHERAPEUTIC AND BIORHYTHMOLOGICAL PECULIARITIES OF DEPRESSIVE DISORDERS, COMORBID WITH CARDIOVASCULAR PATHOLOGY.

Georgian Med News 2021 Mar(312):57-61

2Communal Еnterprise «Regional Institution for Providing Psychiatric Care of Poltava Regional Council», Ukraine.

The spread of depressive disorders is extra high nowadays. Depressive disorders are widespread mental disorders in the structure of mental pathology, both causes of psychiatrists' visit, and causes of medical aid. The presence of depressive syndrome in patients with cardiovascular system leads to deterioration patient's condition and adaptive abilities and aggravates somatic abnormality. Read More

View Article and Full-Text PDF

CLINICAL AND GENETIC FACTORS OF CARDIOVASCULAR EVENTS DEVELOPMENT AFTER PERCUTANEOUS CORONARY INTERVENTION.

Georgian Med News 2021 Mar(312):52-56

NJSC "Medical University of Karaganda", Kazakhstan.

The new cardiovascular events development remains the main factors limiting its long-term effectiveness despite technological progress and the widespread use of percutaneous coronary intervention (PCI). Objective - to assess the effect of clinical and genetic factors on the development of complication after percutaneous coronary intervention with double antiplatelet therapy (DAT). Case-control. Read More

View Article and Full-Text PDF

[REMODELING OF THE LEFT VENTRICLE, SUBCLINICAL MANIFESTATIONS OF ATHEROSCLEROSIS IN PATIENTS WITH HYPERTONIC DISEASE WITH RHEUMATOID ARTHRITIS BY THE INFLUENCE OF DIFFERENT TREATMENT SCHEMES].

Authors:
Y Ivashchuk

Georgian Med News 2021 Mar(312):46-52

State Institution "Zaporozhye Medical Academy of Postgraduate Education" of the Ministry of Health of Ukraine.

Objective - to determine the features of the daily profile of blood pressure (BP), blood lipid spectrum, features of left ventricular remodeling in patients with hypertension in combination with RA and to evaluate the effectiveness of using medium doses of rosuvastatin to correct dyslipidemia in this group of patients. 70 patients aged 40-65 years were examined (average - M±m - 54.88±0. Read More

View Article and Full-Text PDF

ADIPOCYTOKINES LEPTIN AND ADIPONEСTIN AS PREDICTORS OF GENERALIZED PERIODONTITIS ASSOCIATED WITH OBESITY.

Georgian Med News 2021 Mar(312):42-46

Bogomolets National Medical University, Institute of Postgraduate Education, Department of Dentistry, Kyiv, Ukraine.

In recent years, according to the WHO, more than 1,9 billion people over the age of 18 are overweight, of whom more than 650 million are obese, with an annual trend. Studies in recent decades have shown that obese young people with generalized periodontitis have abnormalities in protein, fat and carbohydrate metabolism, which contributes to the early destruction of the periodontal tissue complex and rapid tooth loss. The aim of our study was to examine changes in serum leptin and adiponectin in patients with generalized periodontitis on the background of obesity. Read More

View Article and Full-Text PDF

[TELOMERASE ACTIVITY AS A POTENTIAL BIOMARKER FOR PREOPERATIVE DIFFERENTIAL DIAGNOSIS OF CYSTIC NEOPLASMS OF THE LIVER].

Georgian Med News 2021 Mar(312):31-36

I.M. Sechenov First State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation.

The goal of the study was to find ways to improve the quality of preoperative diagnosis of mucinous cystic liver neoplasms using such tumor markers as CA 19-9 and telomerase activity. We conducted a retrospective analysis and a prospective study that included the results of treatment of 80 patients with cystic neoplasm of the liver (31 with MCNL, 36 with multichamber non-parasitic cysts (NPC), 13 with stage II (WHO classification) echinococcus liver cysts. Our study showed the presence of telomerase activity in 29 (93. Read More

View Article and Full-Text PDF

IMPROVEMENT OF TREATMENT OF COMPLICATED FORMS OF DIABETIC FOOT SYNDROME.

Georgian Med News 2021 Mar(312):27-31

Bukovinian State Medical University, Chernivtsi, Ukraine.

Considering an increasing the incidence of diabetes mellitus, the aim of the study was to improve the results of treatment of patients with diabetic foot syndrome due to the proposed complex VAC-associated therapy. The use of this method within 5 days of treatment was increased the local blood flow of the wounds from 26-31 to 49-53 mm Hg (p<0.01), while in the comparison group the blood flow was at the level of 32-37 mm Hg. Read More

View Article and Full-Text PDF

REDO LAPAROSCOPIC ANTIREFLUX SURGERY IN PATIENTS WITH HIATAL HERNIA.

Georgian Med News 2021 Mar(312):23-26

2Ivane Javakhishvili Tbilisi State University, Georgia.

The purpose was to study the features and results of redo laparoscopic antireflux surgery. For the period from 2008 to 2019, in Odessa Regional Hospital laparoscopic antireflux operations were performed in 1164 patients. 57 patients underwent laparoscopic reoperation during the study period based on the following indications: recurrence of hiatal hernia (n=37), recurrent reflux (n=4), dysphagia (n=8), severe pain (n=5), esophageal stricture (n=3). Read More

View Article and Full-Text PDF

[NON-SURGICAL ASPECTS OF THYROID SURGERY].

Georgian Med News 2021 Mar(312):14-22

1I.M. Sechenov First Moscow State Medical University (Sechenov University), Department of Faculty Surgery N2, Russian Federation.

The level of calcium in the blood serum, voice function, thyroid status and quality of life of patients up to 1 year after removal of the thyroid gland were studied. Thyroidectomy is an operation associated with a high risk of postoperative hypocalcemia with clinical manifestations (19.6%), which is transient in 15. Read More

View Article and Full-Text PDF

[COMPLEX TREATMENT OF PATIENTS WITH VENOUS TROPHIC ULCER IN THE CONDITIONS OF COVID-19 HOSPITAL].

Georgian Med News 2021 Mar(312):7-14

Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of the Russian Federation.

The aim of the study was to study the effectiveness of complex treatment of decompensated chronic venous insufficiency (CVI) using innovative techniques and proteolysis inhibitors with a wide spectrum of activity in patients with SARS-CoV-2 (COVID-19) in COVID hospital. This study was performed in the surgical department of COVID hospital on the basis of the Clinical Hospital No. 4 of the First Moscow State Medical University named I. Read More

View Article and Full-Text PDF

APE1 facilitates PD-L1-mediated progression of laryngeal and hypopharyngeal squamous cell carcinoma.

Int Immunopharmacol 2021 May 6;97:107675. Epub 2021 May 6.

Department of Otolaryngology Head and Neck Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China. Electronic address:

Laryngeal squamous cell carcinoma (LSCC) and hypopharyngeal squamous cell carcinoma (HSCC) seriously affect the life quality of patients. Nowadays, immunotherapy is widely used in the treatment of cancer. Tumor-infiltrating lymphocytes (TILs), programmed cell death 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) play key roles in the immunotherapy of cancer. Read More

View Article and Full-Text PDF

Automated detection of hippocampal sclerosis: Comparison of a composite MRI-based index with conventional MRI measures.

Epilepsy Res 2021 Apr 9;174:106638. Epub 2021 Apr 9.

Department of Radiology, Sanbo Brain Hospital, Capital Medical University, China. Electronic address:

Purpose: This study aims to compare the performance of an MRI-based composite index (HSI) with conventional MRI-based measures in hippocampal sclerosis (HS) detection and postoperative outcome estimation.

Methods: Seventy-two temporal lobe epilepsy (TLE) patients with pathologically confirmed HS and fifteen TLE patients without HS were included retrospectively. The T1-weighted and FLAIR images of these patients were processed with AccuBrain to quantify the hippocampal volume (HV) and the hippocampal FLAIR signal. Read More

View Article and Full-Text PDF

Comparison in detection of prodromal Parkinson's disease patients using original and updated MDS research criteria in two independent cohorts.

Parkinsonism Relat Disord 2021 Apr 30;87:48-55. Epub 2021 Apr 30.

Department of Neurology, P. J. Safarik University, Trieda SNP 1, 04011, Kosice, Slovak Republic; Department of Neurology, University Hospital L. Pasteur, Rastislavova 43, 04190, Kosice, Slovak Republic.

Introduction: MDS research criteria for prodromal Parkinson's disease (pPD) were published in 2015 and updated in 2019. We aimed to determine the difference in pPD patient detection rates in two cohorts recruited via gastrointestinal symptoms (PARCAS study) and the presence of a probable REM sleep behaviour disorder (PDBIOM study) using the original and updated criteria.

Methods: We evaluated all risk and prodromal markers, except genetic testing, plasma urate and physical inactivity, in both cohorts and DaT scan, diabetes mellitus type II and cognitive deficit in the PARCAS cohort. Read More

View Article and Full-Text PDF

LCA and economic study on the local oxygen supply in Central Europe during the COVID-19 pandemic.

Sci Total Environ 2021 Apr 29;786:147401. Epub 2021 Apr 29.

AGH University of Science and Technology, Faculty of Energy and Fuels, Department of Coal Chemistry and Environmental Sciences, Al. Mickiewicza 30, 30-059 Kraków, Poland. Electronic address:

Medical oxygen is the key to survival for COVID-19 patients. To meet the pandemic-driven oxygen demand spike, local hospitals began searching for a suitable medical oxygen delivery system. Among the studies published on the impact of COVID-19 on a range of aspects, including the global economy and the environment, no study has been conducted on the environmental impact of medical oxygen supply to hospitals under epidemic conditions. Read More

View Article and Full-Text PDF

Shorter outpatient wait-times for buprenorphine are associated with linkage to care post-hospital discharge.

Drug Alcohol Depend 2021 Apr 20;224:108703. Epub 2021 Apr 20.

Department of Medicine, Boston University School of Medicine, 801 Massachusetts Ave, Boston, MA, 02118, USA.

Background: Inpatient addiction consult services (ACS) lower barriers to accessing medications for opioid use disorder (MOUD), however not every patient recommended for MOUD links to outpatient care. We hypothesized that fewer days between discharge date and outpatient appointment date was associated with improved linkage to buprenorphine treatment among patients evaluated by an ACS.

Methods: We extracted appointment and demographic data from electronic medical records and conducted retrospective chart review of adults diagnosed with opioid use disorder (OUD) evaluated by an ACS in Boston, MA between July 2015 and August 2017. Read More

View Article and Full-Text PDF

The association between treatment and systemic inflammation in acromegaly.

Growth Horm IGF Res 2021 Apr 30;57-58:101391. Epub 2021 Apr 30.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

Objective: Acromegaly is characterized by an excess of growth hormone (GH) and insulin like growth-factor 1 (IGF1), and it is strongly associated with cardiovascular diseases (CVD). Both acute and long-lasting pro-inflammatory effects have been attributed to IGF1. Previous results suggest the presence of systemic inflammation in treated patients. Read More

View Article and Full-Text PDF

Jejunal GIST masquerading as an ovarian mass: A case report.

Int J Surg Case Rep 2021 May 3;82:105960. Epub 2021 May 3.

Department of GI and General Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.

Introduction And Importance: Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors originating in the wall of the gastrointestinal tract. Jejunal GIST is the rarest subtype. Large GIST can present with an abdominopelvic mass which can be preoperatively misdiagnosed as a gynecological tumor. Read More

View Article and Full-Text PDF

Communication and empathy skills: Essential requisites for patient-centered radiology care.

Eur J Radiol 2021 May 3;140:109754. Epub 2021 May 3.

Department of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

Purpose: To investigate how patients value radiologists, using data from the Dutch healthcare assessment website.

Method: The Dutch healthcare assessment website was searched for patient reviews about radiologists in The Netherlands. The scores (scale of 1-10) assigned to the most recent review of each radiologist were extracted. Read More

View Article and Full-Text PDF

Risk assessment of vertebral compressive fracture using bone mass index and strength predicted by computed tomography image based finite element analysis.

Clin Biomech (Bristol, Avon) 2021 Apr 23;85:105365. Epub 2021 Apr 23.

Inazawa Municipal Hospital, Department of Neurosurgery, Inazawa, Aichi 492-8510, Japan.

Background: A main purpose of osteoporosis diagnosis is to evaluate the bone fracture risk. Some bone mass indices evaluated using bone mineral density has been utilized clinically to assess the degree of osteoporosis. On the other hand, Computed tomography image based finite element analysis has been developed to evaluate bone strength of vertebral bodies. Read More

View Article and Full-Text PDF

Vestibular disorders in children: A retrospective analysis of vestibular function test findings.

Int J Pediatr Otorhinolaryngol 2021 Apr 29;146:110751. Epub 2021 Apr 29.

Acibadem Maslak Hospital ENT Department, Istanbul, Turkey.

Objective: This study was designed to describe the most common vestibular disorders in children and their associated findings on vestibular function testing.

Method: Data from 203 children with a mean age of 11.16 ± 3. Read More

View Article and Full-Text PDF

Conductive hearing loss in large vestibular aqueduct syndrome -clinical observations and proof-of-concept predictive modeling by a biomechanical approach.

Int J Pediatr Otorhinolaryngol 2021 Apr 29;146:110752. Epub 2021 Apr 29.

ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, 200031, China. Electronic address:

Objective: The purpose of this study was to investigate the effect of a dilated vestibular aqueduct on conductive hearing loss (CHL). A biomechanical method was proposed for modeling the patterns of CHL in patients with large vestibular aqueduct syndrome (LVAS).

Study Design: High resolution computed tomography (CT) scans and pure tone audiometry (PTA) were retrospectively collected from 16 patients who were diagnosed with LVAS. Read More

View Article and Full-Text PDF

Clinical characteristics of paediatric Hashimoto's encephalopathy.R2 clean.

Eur J Paediatr Neurol 2021 Apr 30;32:122-127. Epub 2021 Apr 30.

Department of Paediatrics, Medical Centre Leeuwarden, P.O. Box 888, 8901, BR, Leeuwarden, the Netherlands. Electronic address:

Background: Hashimoto's encephalopathy, also known as steroid responsive encephalopathy, is associated with thyroid antibodies (SREAT) and is a rare but serious form of encephalopathy. In this paper, we describe the signs, symptoms, outcome, and treatments as noted in the case reports reviewed.

Methods: We searched PubMed, Embase, and the Cochrane library for articles in which cases of Hashimoto's encephalopathy were described. Read More

View Article and Full-Text PDF

Challenges in Predicting Discharge Disposition for Trauma and Emergency General Surgery Patients.

J Surg Res 2021 May 5;265:278-288. Epub 2021 May 5.

Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

Background: Changes in discharge disposition and delays in discharge negatively impact the patient and hospital system. Our objectives were to determine the accuracy with which trauma and emergency general surgery (TEGS) providers could predict the discharge disposition for patients and determine the factors associated with incorrect predictions.

Methods: Discharge dispositions and barriers to discharge for 200 TEGS patients were predicted individually by members of the multidisciplinary TEGS team within 24 h of patient admission. Read More

View Article and Full-Text PDF

Iatrogenic Ureteral Injury and Prophylactic Stent Use in Veterans Undergoing Colorectal.

J Surg Res 2021 May 5;265:272-277. Epub 2021 May 5.

Michael and Marian Ilitch Department of Surgery, Wayne State University School of Medicine / Detroit Medical Center, Detroit, Michigan; John D. Dingell VA Medical Center, Detroit, Michigan. Electronic address:

Introduction: Iatrogenic ureteral injury (IUI) is an uncommon complication in colorectal surgery. Prophylactic ureteral stenting (PUS) gained acceptance to aid in intraoperative identification of the ureter. Despite its use, the benefit of pus to avoid IUI remains debatable. Read More

View Article and Full-Text PDF

Clinicopathological characteristics and outcomes in embryonal tumor with multilayered rosettes: A decade long experience from a tertiary care centre in North India.

Ann Diagn Pathol 2021 Apr 19;53:151745. Epub 2021 Apr 19.

Departments of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Embryonal tumor with multilayered rosettes (ETMR) are a heterogenous group clinically, pathologically and topographically. Due to limited cases, data regarding its molecular genetics, pathology and prognostic factors is evolving. We retrospectively analysed our cohort of ETMR over last decade in order to study their clinicopathological characteristics and outcome. Read More

View Article and Full-Text PDF

Cognitive network hyperactivation and motor cortex decline correlate with ALS prognosis.

Neurobiol Aging 2021 Mar 10;104:57-70. Epub 2021 Mar 10.

Academic Unit of Neurology, Trinity College Dublin, the University of Dublin, Dublin 2, Ireland.

We aimed to quantitatively characterize progressive brain network disruption in Amyotrophic Lateral Sclerosis (ALS) during cognition using the mismatch negativity (MMN), an electrophysiological index of attention switching. We measured the MMN using 128-channel EEG longitudinally (2-5 timepoints) in 60 ALS patients and cross-sectionally in 62 healthy controls. Using dipole fitting and linearly constrained minimum variance beamforming we investigated cortical source activity changes over time. Read More

View Article and Full-Text PDF