349,758 results match your criteria medical history

Prevalence, epidemiology and associated healthcare burden of Rome IV irritable bowel syndrome and functional dyspepsia in the adult population of Gibraltar.

BMJ Open Gastroenterol 2022 Aug;9(1)

Division of Gastroenterology and Hepatology Center for Functional GI and Motility Disorders, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.

Objective: Gibraltar is a unique densely populated multicultural British Overseas Territory for which no population data on disorders of gut-brain interaction have existed.We aimed to provide the first-ever assessment of prevalence of irritable bowel syndrome and functional dyspepsia in Gibraltar in relation to their diagnostic recognition and healthcare burden.

Design: An internet survey was carried out in Gibraltar in 2019-2020. Read More

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Zinc finger protein 33B demonstrates sex-interaction with atopy-related markers in childhood asthma.

Eur Respir J 2022 Aug 11. Epub 2022 Aug 11.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Background: Sex differences related to immune responses can influence atopic manifestations in childhood asthma. While genome-wide association studies have investigated a sex-specific genetic architecture of the immune response, gene-by-sex interactions have not extensively been analyzed for atopy-related markers including allergy skin tests, immunoglobulin E, and eosinophils in child asthmatics.

Methods: We performed a genome-wide gene-by-sex interaction analysis for atopy-related markers using whole genome sequencing data based on 889 trios from the Genetic Epidemiology of Asthma in Costa Rica Study (GACRS) and 284 trios from the Childhood Asthma Management Program (CAMP). Read More

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Incidence and Risk Factors of Immediate Hypersensitivity Reactions and Immunisation Stress-related Responses with COVID-19 mRNA Vaccine.

J Allergy Clin Immunol Pract 2022 Aug 8. Epub 2022 Aug 8.

Self-Defence Forces Tokyo Large-scale Vaccination Centre, Tokyo, Japan; Self-Defence Forces Central Hospital, Department of Urology, Tokyo, Japan.

Background: With the implementation of mass vaccination campaigns against COVID-19, the safety of vaccine needs to be evaluated.

Objective: We aimed to assess the incidence and risk factors for immediate hypersensitivity reactions (IHSR) and immunisation stress-related responses (ISRR) with the Moderna COVID-19 vaccine.

Methods: This nested case-control study included recipients who received the Moderna vaccine at a mass vaccination centre, Japan. Read More

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Rose Bengal Photodynamic Antimicrobial Therapy: A review of the intermediate term clinical and surgical outcomes.

Am J Ophthalmol 2022 Aug 8. Epub 2022 Aug 8.

Anne Bates Leach Eye Center, Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USA; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:

Purpose: To evaluate the intermediate term clinical outcomes of Rose Bengal Photodynamic Antimicrobial Therapy (RB-PDAT) for infectious keratitis. Secondarily, to evaluate the surgical outcomes of individuals that underwent optical keratoplasty after RB-PDAT.

Design: Retrospective cohort study. Read More

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Bowel obstruction secondary to gallstone ileus within a strangulated inguinal hernia: Report of a rare diagnosis.

Int J Surg Case Rep 2022 Jul 21;97:107445. Epub 2022 Jul 21.

Department of Surgery, Shahid Madani Hospital, Alborz University of Medical Sciences, Alborz, Iran. Electronic address:

Introduction: Gallstone ileus is rare and inguinal hernias are common causes of intestinal obstruction but combination of them is a very rare cause of intestinal obstruction. It is accepted that in patients with severe comorbidities surgeons can manage inguinal hernias and gallstone conservatively. In this article we report a patient with gallstone and inguinal hernia that managed with conservatively management because of heart failure but admitted with complication of gallstone and hernia and treated successfully. Read More

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The story behind the first few cases of monkeypox infection in non-endemic countries, 2022.

J Infect Public Health 2022 Aug 5;15(9):970-974. Epub 2022 Aug 5.

Consultant, Community Medicine Department, Primary Health Care Corporation (PHCC), Doha, Qatar; Associate Professor, Community Medicine Department, College of Medicine, Sousse University, Tunisia. Electronic address:

Starting May 6, 2022, a rising number of monkeypox cases started to be detected in different countries where the disease is not endemic. About 24 countries reported cases by May 28 mostly in Europe. Most of the reported cases so far were among young men particularly men who have sex with men or had a travel history to countries where cases are being registered. Read More

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Intermediate Cervical Plexus Block for Refractory Bilateral Facial Pain From a Whiplash Injury in 3 Patients: A Case Report.

A A Pract 2022 Aug 10;16(8):e01612. Epub 2022 Aug 10.

Department of Pain Medicine, Clinical Research Unit of Pain Medicine, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.

Bilateral facial pain is associated with temporomandibular joint dysfunction and rarely, trigeminal neuralgia. In the absence of clinical and radiological signs, a diagnosis of persistent idiopathic facial pain is often made. Standard management of persistent idiopathic facial pain includes pharmacotherapy and psychotherapy with variable therapeutic efficacy. Read More

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Large socioeconomic gap in period life expectancy and life years spent with complications of diabetes in the Scottish population with type 1 diabetes, 2013-2018.

PLoS One 2022 11;17(8):e0271110. Epub 2022 Aug 11.

Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, United Kingdom.

Background: We report the first study to estimate the socioeconomic gap in period life expectancy (LE) and life years spent with and without complications in a national cohort of individuals with type 1 diabetes.

Methods: This retrospective cohort study used linked healthcare records from SCI-Diabetes, the population-based diabetes register of Scotland. We studied all individuals aged 50 and older with a diagnosis of type 1 diabetes who were alive and residing in Scotland on 1 January 2013 (N = 8591). Read More

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Characterization of Risk Factors Among Individuals with a History of Incarceration Presenting to a Sexually Transmitted Infections Clinic: Implications for HIV and STI Prevention and Care.

AIDS Patient Care STDS 2022 Aug;36(8):291-299

School of Public Health, Brown University, Providence, Rhode Island, USA.

More than 2 million people are incarcerated in the United States with many millions more processed through correctional facilities annually. Communities impacted by incarceration are also disproportionately impacted by the HIV and sexually transmitted infection (STI) epidemics. However, relatively little is known about the behaviors that place individuals with a history of incarceration at risk for HIV/STI acquisition. Read More

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The 'false hope' argument in discussions on expanded access to investigational drugs: a critical assessment.

Med Health Care Philos 2022 Aug 11. Epub 2022 Aug 11.

Department of Medical Ethics, Philosophy and History of Medicine, Erasmus MC, University Medical Centre Rotterdam, Wytemaweg 80, 3015, Rotterdam, CN, The Netherlands.

When seriously ill patients reach the end of the standard treatment trajectory for their condition, they may qualify for the use of unapproved, investigational drugs regulated via expanded access programs. In medical-ethical discourse, it is often argued that expanded access to investigational drugs raises 'false hope' among patients and is therefore undesirable. We set out to investigate what is meant by the false hope argument in this discourse. Read More

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Chronic Chagas Disease-the Potential Role of Reinfections in Cardiomyopathy Pathogenesis.

Curr Heart Fail Rep 2022 Aug 11. Epub 2022 Aug 11.

Department of Medicine, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO, USA.

Purpose Of The Review: Chagas disease is a neglected anthropozoonosis of global importance with significant cardiovascular-associated mortality. This review focuses on the Trypanosoma cruzi reinfections' role in chronic Chagas cardiomyopathy pathogenesis. We discuss and summarize the available data related to pathology, pathogenesis, diagnosis, and treatment of reinfections. Read More

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Tumor-to-tumor metastasis of colon cancer metastasizing to a pancreatic neuroendocrine tumor associated with von Hippel-Lindau disease: a case report.

Clin J Gastroenterol 2022 Aug 11. Epub 2022 Aug 11.

Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Science, Niigata University, Niigata, Japan.

Von Hippel-Lindau disease (VHL) is frequently associated with pancreatic neuroendocrine tumors (PNETs). Here, we report a case of tumor-to-tumor metastasis in a VHL patient in whom colon cancer metastasized to the interior of a PNET. A 65-year-old man had undergone bilateral adrenalectomy for pheochromocytomas in both adrenal glands in his 50 s. Read More

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Benign prostatic hyperplasia is associated with increased 90-day medical complications but not peri-prosthetic joint infections following reverse shoulder arthroplasty.

Eur J Orthop Surg Traumatol 2022 Aug 11. Epub 2022 Aug 11.

Department of Orthopaedic Surgery and Rehabilitation, Maimonides Medical Center, 927 49th Street, Brooklyn, NY, 11219, USA.

Introduction: Studies have shown male sex to be a predisposing factor for peri-prosthetic joint infections (PJIs). Symptomatic benign prostatic hyperplasia (BPH) has been suggested as an additional risk for PJI. This study aimed to assess the impact of BPH on (1) lengths of stay (LOS), (2) complications (medical and implant-related), (3) readmission rates, and (4) healthcare expenditures after reverse shoulder arthroplasty (RSA). Read More

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Parental history of positive development and child behavior in next generation offspring: A two-cohort prospective intergenerational study.

Child Dev 2022 Aug 11. Epub 2022 Aug 11.

Faculty of Health, Centre for Social and Early Emotional Development, School of Psychology, Deakin University, Geelong, Victoria, Australia.

This study examined whether positive development (PD) in adolescence and young adulthood predicts offspring behavior in two Australasian intergenerational cohorts. The Australian Temperament Project Generation 3 Study assessed PD at age 19-28 (years 2002-2010) and behavior in 1165 infants (12-18 months; 608 girls) of 694 Australian-born parents (age 29-35; 2012-2019; 399 mothers). The Dunedin Multidisciplinary Health and Development Parenting Study assessed PD at age 15-18 (years 1987-1991) and behavior in 695 preschoolers (3-5 years; 349 girls) and their New Zealand born parents (age 21-46; 1994-2018; 363 mothers; 89% European ethnicity). Read More

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Mumps serological surveillance following 10 years of a one-dose mumps-containing-vaccine policy in Fujian Province, China.

Hum Vaccin Immunother 2022 Aug 11:2096375. Epub 2022 Aug 11.

Fujian Provincial Key Laboratory of Zoonosis Research, Fujian Provincial Center for Disease Control and Prevention, Fuzhou, China.

Background: Since 2008, Fujian province provided measles-rubella (MR) vaccine at 8 months followed by measles-mumps-rubella (MMR) vaccine at 18 months a one-dose mumps-containing-vaccine (MuCV) schedule. Several mumps outbreaks have occurred recently in Fujian. Serological surveillance can assess population immunity to mumps and identify risk factors for mumps. Read More

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Could serum endocannabinoid and N-acylethanolamine levels be important in bipolar disorder?

World J Biol Psychiatry 2022 Aug 11:1-23. Epub 2022 Aug 11.

Department of Psychiatry Faculty of Medicine, Trakya University, 22030-Edirne, Turkey.

The endocannabinoid system (ECS) is a critical important neuromodulatory system that interacts with many neurohormoneand neurotransmitter systems in the brain. It plays a pivotal role in emotional responses and mood regulation. The endocannabinoid system is related with psychotic disorders, depression, anxiety and autism. Read More

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Chinese Medicine in the Treatment of Ulcerative Colitis: The Mechanisms of Signaling Pathway Regulations.

Am J Chin Med 2022 Aug 11:1-18. Epub 2022 Aug 11.

Graduate School, Hebei University of Traditional Chinese Medicine, Shijiazhuang 050091, P. R. China.

Ulcerative colitis (UC) is a common clinical inflammatory bowel disease characterized by repeated attacks, difficult treatment, and great harm to the physical and mental health of the patients. The occurrence and development of UC were closely related to the physiological and pathological processes, such as intestinal inflammatory reaction, oxidizing reaction, and immune response. Treatment of ulcerative colitis using Western medicine is often associated with a number of limitations and adverse events. Read More

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Cucumis melo var. momordica as a potent antidiabetic, antioxidant and possible anticovid alternative: Investigation through experimental and computational methods.

Chem Biodivers 2022 Aug 11. Epub 2022 Aug 11.

Higher medical and biological school, drug design, prospect lenina, 454008, chelyabinsk, RUSSIAN FEDERATION.

Diabetes mellitus is a typical life threatening of disease, which generate due to the dysfunction of β cells of pancreas. In 2014, WHO stated that 422 million people were infected with DM. The current pattern of management of diabetes included synthetic or plant based oral hypoglycemic drugs and insulin but drug resentence is become a very big issues in antidiabetic therapy. Read More

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Malignant pericardial effusions: A retrospective look at etiology and prognosis in a tertiary oncological center.

Asia Pac J Clin Oncol 2022 Aug 10. Epub 2022 Aug 10.

Department of Cardiology, Calvary Mater Hospital, Newcastle, New South Wales, Australia.

Purpose: Cancer and the associated treatments are important causes of pericardial effusion. However, the natural history of malignant pericardial effusion is largely unknown, especially in the context of newer cancer treatments. We investigated the causes of pericardial effusions in a tertiary oncology center, with particular focus on the prognosis of malignant effusions in the era of contemporary oncological therapies. Read More

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Unresectable Primary Tracheal Synovial Sarcoma.

Ear Nose Throat J 2022 Aug 10:1455613221113815. Epub 2022 Aug 10.

Department of Pulmonary, Allergy, and Critical Care Medicine, 389402Abington Jefferson Health, Abington, PA, USA.

Synovial sarcoma (SS) comprises less than 1% of head and neck cancers, and less than five cases of adult primary tracheal SS have been described. This case describes a patient encountered at a community-based academic hospital, and retrospective chart review was performed for data collection. A woman in her forties presented with shortness of breath due to a superior mediastinal mass found to be an unresectable primary tracheal SS. Read More

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Tailoring the therapeutic interventions for behavioral and psychological symptoms of dementia.

Expert Rev Neurother 2022 Aug 10. Epub 2022 Aug 10.

Laboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka cesta 54, 10000 Zagreb, Croatia.

Introduction: Behavioral and psychological symptoms of dementia (BPSD) are symptoms of non-cognitive nature, which frequently develop during the course and different stages of dementia. The diagnosis of BPSD is complex due to symptom variety, and relies on detailed clinical evaluation and medical history. Accurate assessment of BPSD is crucial in order to tailor therapeutic intervention (non-pharmacological and pharmacological) for each individual and monitor patient response to therapy. Read More

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Association between serum chlamydial antibody levels and tubal infertility in tertiary health facility in South-East Nigeria: a case-control study.

Ghana Med J 2021 Sep;55(3):183-189

Department of Obstetrics and Gynaecology, Federal Medical Centre, Owerri, Nigeria.

Objectives: This study evaluates the association between genital Chlamydial infection and tubal factor infertility in a tertiary health facility in South-East Nigeria.

Design: This was a case-control analytical study.

Setting: Gynaecology Clinic and Maternity Unit of the Department of Obstetrics and Gynaecology of the Federal Medical Centre (FMC), Owerri, Imo State, Nigeria. Read More

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September 2021

Constrictive pericarditis following inactivated virus COVID-19 vaccine: a case report with review of the literature.

Radiol Case Rep 2022 Oct 5;17(10):3774-3778. Epub 2022 Aug 5.

Faculty of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Cardiac adverse effects of the COVID-19 vaccine are very rare, myocarditis and pericarditis are the most common amid them, and constrictive pericarditis (CP) is reported to be restricted to a few cases following mRNA COVID-19 vaccines. We report a case of a 72-year-old male patient who developed symptoms of right-sided heart failure, which started after 8 days of receiving the third dose of inactivated virus COVID-19 vaccine and his diagnostic tests comprising transthoracic echocardiography, chest CT scan, cardiac magnetic resonance were in favor of CP. Ultimately, invasive cardiac catheterization confirmed the diagnosis of CP. Read More

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October 2022

Varicella-Zoster Virus Encephalitis in an Immunocompetent Adult with Disseminated Cutaneous Herpes Zoster after Testosterone Booster Supplements: Case Report.

Case Rep Dermatol 2022 May-Aug;14(2):164-168. Epub 2022 Jun 27.

Department of Dermatology and Dermatologic Surgery, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Disseminated zoster affects immunocompromised individuals and has a nondermatomal distribution. We report a 28-year-old male who initially presented to the dermatology clinic with pinprick sensation over the right side of his face that was followed by vesicular eruption. Upon which he was diagnosed with herpes zoster and discharged on topical mupirocin ointment three times a day for 7 days and valacyclovir 1 g oral three times a day. Read More

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Pathogenetic aspects of chronic urticaria. Retrospective and prospective analysis of the patients of the Department of Dermatology, Poznan University of Medical Sciences.

Postepy Dermatol Alergol 2022 Jun 25;39(3):587-593. Epub 2021 Oct 25.

Department of Allergic and Occupational Skin Diseases, Poznan University of Medical Sciences, Poznan, Poland.

Introduction: Urticaria is a disease with a complex pathomechanism. Confirmation of the cause in chronic urticaria seems to be a great challenge for specialists.

Aim: To assess the frequency of different types of urticaria and their coexistence in 1 patient, diseases associated with chronic urticaria and the frequency of accompanying oedema. Read More

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Eosinophil Levels, Neutrophil-Lymphocyte Ratio, and Platelet-Lymphocyte Ratio in the Cytokine Storm Period of Patients with COVID-19.

Int J Clin Pract 2022 3;2022:7450739. Epub 2022 Aug 3.

Bursa City Hospital Medical Biochemistry, Bursa, Turkey.

Background: In the early stages of the COVID-19 pandemic, elevated inflammatory cytokine levels, particularly interleukin-6 (IL-6), were detected in patients with cytokine storm (CS).

Aims: This study aimed to investigate levels, diagnostic usefulness, and optimal cutoff values of monocyte, eosinophil, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in CS of patients with COVID-19 and also to identify risk factors for mortality.

Methods: Seventy-six patients with COVID-19 who developed CS and randomly chosen 150 COVID-19 patients who had no CS during their stay in the hospital were included in the study. Read More

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Prevalence of chronic traumatic encephalopathy in the Sydney Brain Bank.

Brain Commun 2022 1;4(4):fcac189. Epub 2022 Aug 1.

Neuroscience Research Australia, Randwick, NSW 2031, Australia.

Chronic traumatic encephalopathy neuropathologic change can only be definitively diagnosed post-mortem. It has been associated with repetitive mild neurotrauma sustained in amateur and professional contact, collision and combat sports, although it has also been documented in people with a single severe traumatic brain injury and in some people with no known history of brain injury. The characteristic neuropathology is an accumulation of perivascular neuronal and astrocytic phosphorylated tau in the depths of the cortical sulci. Read More

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Brain Magnetic Resonance Imaging Findings in Patients with Developmental Delay in Addis Ababa, Ethiopia.

Ethiop J Health Sci 2022 Jul;32(4):773-780

Department of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Developmental delay is a major health problem throughout the world causing significant individual disability. Even though physical examination and patient history are the most important and basic evaluations of patients with developmental delay, additional investigations are usually required in supporting or reaching a diagnosis among which is neuroimaging. This study aims to assess brain Magnetic resonance imaging (MRI) patterns in patients presented with developmental delay. Read More

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Geriatric Syndromes among Patients with Rheumatoid Arthritis: A Comparison between Young and Elderly Patients.

Ethiop J Health Sci 2022 Jul;32(4):791-798

Firoozabadi Clinical and Research Development Unit, Iran University of Medical Sciences, Tehran, Iran.

Background: In the general geriatric population, Geriatric syndromes (GSs) predict greater likelihood of hospitalization, increased health care use and cost. The present study aimed to compare GSs among young and elderly patients with rheumatoid arthritis (RA).

Methods: In a cross-sectional study a total of 98 participants, including 65 elderly (≥60 years) and 33 young adult patients (<60 years) with RA who referred to the geriatric and rheumatologic clinic were enrolled. Read More

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