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Variability in outcomes and quality-of-care indicators across clinics participating in a large smoking-cessation program.

J Subst Abuse Treat 2021 Apr 14;130:108409. Epub 2021 Apr 14.

Nicotine Dependence Services, Centre for Addiction and Mental Health, 175 College St, Toronto, ON M5T 1P7, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 60 White Squirrel Way, Toronto, ON M6J 1H4, Canada; Department of Family and Community Medicine, University of Toronto, 500 University Ave, Toronto, ON M5G 1V7, Canada; Dalla Lana School of Public Health, University of Toronto, 155 College, Toronto, ON M5T 3M7, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, ON M5T 1R8, Canada. Electronic address:

Background: The effectiveness of care for substance-related problems varies across providers. Best-known treatments are rarely universally applied, and various process differences can affect participant outcomes. Measuring and understanding this variability can suggest changes that will improve system performance. Read More

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Long-term follow-up of ruxolitinib in the treatment of steroid-refractory chronic graft-versus-host disease (GVHD).

Transplant Cell Ther 2021 Jun 9. Epub 2021 Jun 9.

Bone Marrow Transplant, Hospital Sirio Libanes, São Paulo, Brazil; Division of Hematology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.

Chronic graft-versus-host disease (cGVHD) remains a major barrier to a successful hematopoietic stem cell transplantation (HSCT); in cases refractory to first-line therapy with steroids, there is no standard of care for second-line therapy. As such, ruxolitinib is a promising drug in this scenario. We retrospectively analyzed its efficacy and safety as treatment of steroid-refractory cGVHD in 35 patients from two transplant centers, with the longest follow-up described to date. Read More

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Enhanced immune reconstitution of γδ T cells after allograft overcomes negative impact of pre-transplant MRD positive status in AML patients.: γδ T cells and MRD+ AML.

Transplant Cell Ther 2021 Jun 9. Epub 2021 Jun 9.

Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

Background: Minimal residual disease (MRD) prior to allogeneic stem cell transplantation (allo-SCT) in AML is a poor risk factor for outcome. The γδ T cells represents a unique minority lymphocyte population which is preferentially located in peripheral tissues, can recognize antigens in non-MHC restricted manner and plays a "bridging" role between innate and adaptive immune system.

Objectives: In this study, we investigated a potential graft-vs-leukaemia effect of γδ T cells reconstitution post-transplant in AML patients with pre-transplant positive minimal/measurable disease status (MRD+). Read More

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Long-tevrm outcomes of the MICOF keratoprosthesis surgery.

Ocul Surf 2021 Jun 9. Epub 2021 Jun 9.

Department of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China. Electronic address:

Purpose: To evaluate long-term anatomical and functional outcomes of the MICOF keratoprosthesis to treat end-stage corneal blindness.

Design: Re trospective review of consecutive clinical case series.

Participants: Between October 2000 and October 2015, at the Department of Ophthalmology of Chinese PLA General Hospital (PLAGH), a total of 132 eyes of 131 patients had undergone a MICOF keratoprosthesis implantation. Read More

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Prognostic performance of seven biomarkers compared to liver biopsy in early alcohol-related liver disease.

J Hepatol 2021 Jun 9. Epub 2021 Jun 9.

Department of Gastroenterology and Hepatology, Odense University Hospital, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.

Background & Aims: Alcohol is the most common cause of liver-related mortality and morbidity. We therefore aimed to assess and compare the prognostic performance of elastography and blood-based markers to predict time to the first liver-related event, severe infection, and all-cause mortality in patients with a history of excess drinking.

Methods: Prospective cohort study of patients with early, compensated alcohol-related liver disease. Read More

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Evaluation of the Cancer of Bladder Risk Assessment (COBRA) Score in the Cancer Genome Atlas (TCGA) Bladder Cancer Cohort.

Urology 2021 Jun 9. Epub 2021 Jun 9.

Department of Urology, University of California, San Francisco.

Objectives: To evaluate the Cancer of the Bladder Risk Assessment (COBRA) score in The Cancer Genome Atlas (TCGA) bladder cancer cohort. Second, to investigate the utility of the COBRA score within each bladder cancer molecular subtype following radical cystectomy (RC) and determine if it can help identify candidates for adjuvant therapies and clinical trials.

Methods: Among the TCGA bladder cancer cohort (n=412), RC pathology reports were reviewed to calculate COBRA scores. Read More

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Primary mediastinal large B-cell lymphoma chemotherapy: Impact of chemotherapy choice.

Hematol Oncol Stem Cell Ther 2021 Jun 6. Epub 2021 Jun 6.

Department of Hematology, Kuwait Cancer Control Center, Kuwait. Electronic address:

Objective/background: Data generated from retrospective studies on primary mediastinal B-cell lymphoma (PMBCL) outcome are valuable as no prospective phase 3 trials have been conducted in this rare type of lymphoma.

Methods: Our goal was to assess the long-term outcome of 41 patients with PMBCL who were treated at the Kuwait Cancer Center. We evaluated two types of multidrug treatment, R-CHOP (rituximab, vincristine, doxorubicin, cyclophosphamide, and prednisone) and DA-EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab), and determined overall survival and complete response (CR) as primary endpoints. Read More

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Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States.

J Int AIDS Soc 2021 Jun;24(6):e25747

Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Introduction: Vaginal rings are a promising approach to provide a woman-centred, long-acting HIV prevention strategy. Prior trials of a 25 mg dapivirine (DPV) ring have shown a favourable safety profile and approximately 30% risk reduction of HIV-1 infection. Extended duration rings replaced every three months may encourage user adherence, improve health service efficiency and reduce cost overall. Read More

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Swallowing dysfunction and the onset of fever in older residents with special care needs: a thirteen-month longitudinal prospective study.

Odontology 2021 Jun 12. Epub 2021 Jun 12.

School of Oral Health Sciences, Faculty of Dentistry, Kyushu Dental University, 2-6-1, Manazuru, Kokurakita-ku, Kitakyushu , Fukuoka, 803-8580, Japan.

A decline in swallowing function is frequently observed among older residents in nursing homes. We investigated whether swallowing dysfunction was related to the onset of fever in such individuals. Older residents aged ≥ 65 years from three nursing homes were included in this prospective study conducted from July 2017 to May 2019. Read More

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Living donor liver transplantation for advanced hepatocellular carcinoma including macrovascular invasion.

J Cancer Res Clin Oncol 2021 Jun 12. Epub 2021 Jun 12.

Division of Radiology, Shifa International Hospital Islamabad, Islamabad, Pakistan.

Background: The indications for liver transplantation (LT) in patients with hepatocellular carcinoma (HCC) continue to evolve. The aim of this study was to report outcomes in patients who underwent living donor liver transplantation (LDLT) for HCC outside traditional criteria including macrovascular invasion (MVI).

Methods: We reviewed outcomes in patients who met the University of California San Francisco (UCSF) criteria (n = 159) and our center-specific criteria (UCSF+) (largest tumor diameter ≤ 10 cm, any tumor number, AFP ≤ 1000 ng/ml) (n = 58). Read More

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The Impact of Combat Ocular Trauma and Traumatic Brain Injury on Vision- and Health-Related Quality of Life Among U.S. Military Casualties.

Mil Med 2021 Jun 12. Epub 2021 Jun 12.

Department of Surgery, Uniformed Services University of Health Sciences, Bethesda, MD 20814, USA.

Purpose: The purpose of this study was to assess visual and health-related quality of life (QOL) among U.S. military service members who sustained combat ocular trauma (COT) with or without associated traumatic brain injury (TBI). Read More

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Association of markers of inflammation, the kynurenine pathway and B vitamins with age and mortality, and a signature of inflammaging.

J Gerontol A Biol Sci Med Sci 2021 Jun 12. Epub 2021 Jun 12.

Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.

Background: Inflammation is a key feature of aging. We aimed to i) investigate the association of 34 blood markers potentially involved in inflammatory processes with age and mortality, ii) develop a signature of 'inflammaging'.

Methods: Thirty-four blood markers relating to inflammation, B vitamin status and the kynurenine pathway were measured in 976 participants in the Melbourne Collaborative Cohort Study at baseline (median age=59 years) and follow-up (median age=70 years). Read More

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Is a treat-to-target approach to lipid-lowering therapy appropriate in patients with chronic kidney disease? A prospective French cohort study.

J Nephrol 2021 Jun 11. Epub 2021 Jun 11.

Pharmacology Department, Amiens University Hospital, 80054, Amiens, France.

Background: Whereas European guidelines recommend adjusting lipid-lowering therapy (LLT) to meet prespecified targets ('treat-to-target') for low-density lipoprotein cholesterol (LDL-C), other guidelines do not ('fire and forget'). In a large observational prospective cohort, we sought to evaluate which strategy could be associated with better cardiovascular outcomes in chronic kidney disease (CKD).

Methods: In CKD-REIN, patients (CKD stages 3 and 4) on LLT were categorized according to achievement of LDL-C targets for high and very high cardiovascular risk (< 2. Read More

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Prognostic Impact of Different Gleason Patterns on Biopsy Within Grade Group 4 Prostate Cancer.

Ann Surg Oncol 2021 Jun 11. Epub 2021 Jun 11.

Department of Urology, Medical University of Vienna, Vienna, Austria.

Background: Grade group (GG) 4 prostate cancer (PC) is considered a single entity; however, there are questions regarding prognostic heterogeneity. This study assessed the prognostic differences among various Gleason scores (GSs) classified as GG 4 PC on biopsy before radical prostatectomy (RP).

Methods: We conducted a multicenter retrospective study, and a total of 1791 patients (GS 3 + 5: 190; GS 4 + 4: 1557; and GS 5 + 3: 44) with biopsy GG 4 were included for analysis. Read More

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Integrated I-125 Seed Implantation Combined with Transarterial Chemoembolization for Treatment of Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombus.

Cardiovasc Intervent Radiol 2021 Jun 11. Epub 2021 Jun 11.

Department of Interventional Radiology, First Affiliated Hospital, Soochow University, No. 188 Shizi Road, Suzhou, 215006, China.

Purpose: To compare the safety and efficacy of integrated iodine-125 (I-125) seed implantation (sequential implantation of helical I-125 seed implant into the main portal vein and of I-125 seeds into the branch tumor thrombus directly forming main portal vein tumor thrombus (MPVTT)) combined with transarterial chemoembolization (TACE) versus TACE alone for hepatocellular carcinoma (HCC) with MPVTT.

Materials And Methods: From December 2016 to January 2020, 46 HCC patients with MPVTT were analyzed. In the combination group, 21 patients received helical I-125 seed implantation in the main portal vein through a patent small portal vein branch and TACE in a single session. Read More

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Demography, clinical profile and surgical outcomes of paediatric giant retinal tear related retinal detachments.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Objective: To determine the demographic profile, clinical features and surgical outcomes of giant retinal tear (GRT) related retinal detachments (RD) in children.

Methods: In this retrospective study, medical records of children aged 14 years and below, who underwent surgery for RD at our centre in the last 5 years were reviewed. Among these, we selected medical records of children with RDs with GRT, and examined the coloured retinal drawings, ultrawidefield photographs and/or surgical videos. Read More

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Metformin use is associated with a reduced risk of acute appendicitis in Taiwanese patients with type 2 diabetes mellitus.

Chin-Hsiao Tseng

Sci Rep 2021 Jun 11;11(1):12400. Epub 2021 Jun 11.

Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

This retrospective cohort study used the nationwide database of Taiwan's National Health Insurance to investigate whether metformin would reduce the risk of acute appendicitis in patients with type 2 diabetes mellitus. We first identified 423,949 patients newly diagnosed of diabetes from 1999 to 2005. After excluding patients having type 1 diabetes mellitus, missing data, previous history of acute appendicitis, aged < 15 years, aged > 80 years and followed up for < 6 months, 338,172 ever users and 21,861 never users of metformin were followed up from January 1, 2006 until December 31, 2011. Read More

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Impact of dose-dense neoadjuvant chemotherapy on pathologic response and survival for HER2-positive breast cancer patients who receive trastuzumab.

NPJ Breast Cancer 2021 Jun 11;7(1):75. Epub 2021 Jun 11.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.

To compare outcomes in patients with human epidermal growth factor receptor-2 (HER2)-positive breast cancer who received either dose-dense neoadjuvant chemotherapy (NAC) with trastuzumab or standard-interval chemotherapy with trastuzumab. Patients with HER2-positive breast cancer who received NAC, including epirubicin and cyclophosphamide followed by paclitaxel with trastuzumab were included. Patients were divided into either the dose-dense or standard-interval group. Read More

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Circulating tumor cell number and endocrine therapy index in ER positive metastatic breast cancer patients.

NPJ Breast Cancer 2021 Jun 11;7(1):77. Epub 2021 Jun 11.

Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Rogel Cancer Center, Ann Arbor, MI, USA.

Circulating tumor cells (CTC) are prognostic in metastatic breast cancer (MBC). The CTC-endocrine therapy index (CTC-ETI), consisting of CTC-ER (estrogen receptor), BCL2, human epidermal growth factor receptor (HER2), and Ki67 expression, might predict resistance to endocrine therapy (ET) in patients with ER-positive MBC. One hundred twenty-one patients with ER-positive/HER2-negative MBC initiating a new ET after ≥1 lines of ET were enrolled in a prospective, multi-institutional clinical trial. Read More

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A European Survey on Digestive Perianastomotic Ulcerations, a Rare Crohn-Like Disorder Occurring in Children and Young Adults.

J Pediatr Gastroenterol Nutr 2021 Jun 10. Epub 2021 Jun 10.

Department of pediatric surgery, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, Paris, France Children's Hospital, Zagreb University Medical School, Zagreb, Croatia Centre Hospitalier Universitaire de Saint Etienne, Saint Etienne, France Division of Gastroenterology and Hepatology, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Germany Department of Paediatrics, School of Medicine Collegium Medicum University of Warmia and Mazury, Olsztyn, Poland Hôpital Timone Enfants, service de pédiatrie multidisciplinaire, Marseille, France Aix Marseille Univ, INSERM, MMG, Marseille, France Department of pediatric gastroenterology and nutrition, Hopital Robert Debré, Assistance Publique Hopitaux de Paris, Paris, France Université de Paris ; INSERM UMR1149 ; Paris, France Unidade de Gastrenterologia Pediátrica, Centro Hospitalar do Porto, Porto, Portugal Bordeaux University Hospital, Paediatric Gastroenterology Unit, CIC 1401, F-33000, Bordeaux, France Department of pediatric gastroenterology and nutrition, Hôpital Trousseau, Assistance Publique-Hopitaux de Paris, Paris, France Children's Hospital, University of Helsinki, Helsinki, Finland Centre Hospitalier Lyon Sud, Pierre Bénite, France Pediatric gastroenterology Unit, Ospedale Maggiore Carlo Alberto Pizzardi di Bologna, Bologna, Italy Sapienza University - Umberto I Hospital, Rome, Italy Department of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", Naples, Italy Department of pediatrics, Hospices Civils de Lyon, Lyon, France. University Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000 Lille, France Department of pediatrics. Centre Hospitalier universitaire de Limoges, Limoges, France Department of pediatrics. Centre Hospitalier Universitaire Clocheville, Tours, France Department of pediatrics. University Normandie, UNICAEN, CHU de Caen Normandie, F-14000 Caen, France INSERM UMR 1073, University Rouen, F-76000 Rouen, France Al Jalila Children's Specialty Hospital, Dubai, United Arab Emirates Shaare Zedek Medical Center, Jerusalem, Jerusalem, Israel.

Objectives: Digestive perianastomotic ulcerations (DPAU) resembling Crohn's disease lesions are long-term complications of intestinal resections, occurring in children and young adults. They are known to be uncommon, severe and difficult to treat.

Methods: In the absence of recommendations, we performed a large European survey among the members of the ESPGHAN working group on inflammatory bowel disease (IBD) in order to collect the experience of expert pediatric gastroenterologists on DPAU. Read More

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Women Have Lower Mortality Than Men After Attending a Long-Term Medically Supervised Exercise Program.

J Cardiopulm Rehabil Prev 2021 Jun 10. Epub 2021 Jun 10.

Exercise Medicine Clinic (Clínica de Medicina do Exercício, CLINIMEX), Rio de Janeiro, Brazil (Drs de Souza e Silva, Castro, Franca, and Araújo); Escola de Medicina Souza Marques, Rio de Janeiro, Brazil (Dr Nishijuka); Division of Cardiology, VA Palo Alto, Palo Alto, California, and Stanford University School of Medicine, Stanford, Stanford, California (Dr Myers); and Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland, and Central Finland Health Care District Hospital, Jyväskylä, Finland, and Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland (Dr Laukkanen).

Purpose: Medically supervised exercise programs (MSEPs) are equally recommended for men and women with cardiovascular disease (CVD). Aware of the lower CVD mortality in women, we hypothesized that among patients attending a MSEP, women would also have better survival.

Methods: Data from men and women, who were enrolled in a MSEP between 1994 and 2018, were retrospectively analyzed. Read More

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Association between sleep quality and type 2 diabetes at 20-year follow-up in the Southall and Brent REvisited (SABRE) cohort: a triethnic analysis.

J Epidemiol Community Health 2021 Jun 11. Epub 2021 Jun 11.

MRC Unit for Lifelong Health and Ageing, Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK.

Background: The risk of developing type 2 diabetes associated with poor sleep quality is comparable to other lifestyle factors (eg, overweight, physical inactivity). In the UK, these risk factors could not explain the two to three-fold excess risks in South-Asian and African-Caribbean men compared with Europeans. This study investigates (1) the association between mid-life sleep quality and later-life type 2 diabetes risk and (2) the potential modifying effect of ethnicity. Read More

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Development of a predictive risk model for all-cause mortality in patients with diabetes in Hong Kong.

BMJ Open Diabetes Res Care 2021 Jun;9(1)

Cardiovascular Analytics Group, Laboratory of Cardiovascular Physiology, Hong Kong

Introduction: Patients with diabetes mellitus are risk of premature death. In this study, we developed a machine learning-driven predictive risk model for all-cause mortality among patients with type 2 diabetes mellitus using multiparametric approach with data from different domains.

Research Design And Methods: This study used territory-wide data of patients with type 2 diabetes attending public hospitals or their associated ambulatory/outpatient facilities in Hong Kong between January 1, 2009 and December 31, 2009. Read More

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Statin therapy for patients with aortic stenosis who underwent transcatheter aortic valve implantation: a report from a Japanese multicentre registry.

BMJ Open 2021 Jun 11;11(6):e044319. Epub 2021 Jun 11.

Department of Cardiology, Keio University School of Medicine, Shinjuku-ku, Japan.

Objective: Data on statin for patients with aortic stenosis (AS) who underwent transcatheter aortic valve implantation (TAVI) are limited. The present study aimed to evaluate the impact of statin on midterm mortality of TAVI patients.

Design: Observational study. Read More

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Association of cardiovascular disease risk factors with late cardiotoxicity and survival in HER2-positive breast cancer survivors.

Clin Cancer Res 2021 Jun 11. Epub 2021 Jun 11.

Emergency Medicine, The University of Texas MD Anderson Cancer Center.

Purpose: Breast cancer and cardiovascular diseases often share the same risk factors. It is increasingly important to identify risk factors for cardiovascular (CV) events in high-risk breast cancer patients and explore optimal treatment regimens.

Patients And Methods: Early HER2-positive breast cancer patients at our institution between January 1998 and October 2009 were reviewed. Read More

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Agreement between real-time elastography and delayed enhancement magnetic resonance enterography on quantifying bowel wall fibrosis in Crohn's disease.

Dig Liver Dis 2021 Jun 8. Epub 2021 Jun 8.

Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Via F. Sforza 35, Milan 20122, Italy. Electronic address:

Background: the assessment of fibrosis in Crohn's disease (CD) bowel lesions helps to guide therapeutic decisions. Real-time elastography (RTE) and delayed-enhancement magnetic resonance enterography (DE-MRE) have demonstrated good accuracy in quantifying CD-related ileal fibrosis as compared with histological examination. To date no study has compared DE-MRE and RTE. Read More

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Direct surgery with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for patients with colorectal peritoneal metastases.

Eur J Surg Oncol 2021 Jun 3. Epub 2021 Jun 3.

Department of Molecular Medicine and Surgery, Karolinska Institute, K1 Molekylär Medicin Och Kirurgi, K1 MMK Kolorektalkirurgi, 171 76, Stockholm, Sweden; Department of Pelvic Cancer, GI Oncology and Colorectal Surgery Unit, Karolinska University Hospital, Anna Steckséns Gata 30A, Solna D105, Karolinska Universitetssjukhuset, 17164, Stockholm, Sweden.

Introduction: Neoadjuvant chemotherapy is widely used in treatment of peritoneal metastases from colorectal cancer, but there is little scientific evidence for this approach. This study aimed to study survival in patients treated with direct surgery with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), i.e. Read More

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Structural abnormalities after aortic root replacement with stentless xenograft.

J Thorac Cardiovasc Surg 2021 May 12. Epub 2021 May 12.

Department of Cardiothoracic Surgery, The Heart Center, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.

Objective: In complex and high-risk aortic root disease, the porcine Freestyle stentless bioprosthesis (Medtronic Inc, Minneapolis, Minn) is an important surgical treatment option. We aimed to determine prevalence and clinical effect of structural and functional abnormalities after full-root Freestyle implantation.

Methods: Our cross-sectional 2-center study combined with clinical follow-up included 253 patients with full-root Freestyle bioprostheses implanted from 1999 to 2017. Read More

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Advanced Therapies for Severe Tracheobronchomalacia: A Review of the Use of 3D-Printed, Patient-Specific, Externally Implanted, Bioresorbable Airway Splints.

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2021 ;24:37-43

Section of Pediatric Cardiovascular Surgery, Department of Cardiac Surgery, C.S. Mott Children's Hospital, University of Michigan Medicine, Ann Arbor, Michigan. Electronic address:

Tracheobronchomalacia is a condition of dynamic collapse of the trachea and mainstem bronchi. The clinical significance of tracheobronchomalacia depends on its severity. Mild cases may be medically managed with limited symptomology, while severe cases require advanced therapies, lengthy hospital stays, and carry significant morbidity and mortality. Read More

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January 2021

Post Procedural Peak Left Atrial Contraction Strain Predicts Recurrence of Arrhythmia after Catheter Ablation of Atrial Fibrillation.

Cardiovasc Ultrasound 2021 Jun 11;19(1):22. Epub 2021 Jun 11.

Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, MN, 55905, Rochester, USA.

Background: Left atrial (LA) function can be impaired by the atrial fibrillation (AF) ablation and might be associated with the risk of recurrence. We sought to determine whether the post-procedural changes in LA function impact the risk of recurrence following AF ablation.

Methods: We retrospectively reviewed patients who underwent AF ablation between 2009 and 2011 and underwent transthoracic echocardiography before ablation, 1-day and 3-month after ablation. Read More

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