Pathogens 2021 Apr 12;10(4). Epub 2021 Apr 12.
Center for Food Animal Health, Department of Animal Sciences, The Ohio State University, Wooster, OH 44691, USA.
Avian pathogenic (APEC) causes colibacillosis in avian species, and recent reports have suggested APEC as a potential foodborne zoonotic pathogen. Herein, we discuss the virulence and pathogenesis factors of APEC, review the zoonotic potential, provide the current status of antibiotic resistance and progress in vaccine development, and summarize the alternative control measures being investigated. In addition to the known virulence factors, several other factors including quorum sensing system, secretion systems, two-component systems, transcriptional regulators, and genes associated with metabolism also contribute to APEC pathogenesis. Read More