Neuroscience 2021 Jun 6. Epub 2021 Jun 6.
Department of Anatomy and Cell Biology, School of Medicine, University of Kansas Medical Center, Kansas City, KS, USA; Department of Anesthesiology, School of Medicine, University of Kansas Medical Center, Kansas City, KS, USA. Electronic address:
Inflammation plays a key role in the progression and maintenance of chronic pain, which impacts the lives of millions of Americans. Despite growing evidence that chronic pain can be improved by treating underlying inflammation, successful treatments are lacking and pharmaceutical interventions are limited due to drug side effects. Here we are testing whether a 'healthy human' diet (HHD), with or without anti-inflammatory components (HHAID), improves pain-like behaviors in a preclinical model of chronic widespread hypersensitivity induced by neonatal maternal separation (NMS). Read More