81 results match your criteria measured trans-thoracic

Chronic Chest Pain Control after Trans-Thoracic Biopsy in Mediastinal Lymphomas.

Healthcare (Basel) 2021 May 18;9(5). Epub 2021 May 18.

Pain Department, AORN Dei Colli-V. Monaldi, 80131 Naples, Italy.

Chest pain following a trans-thoracic biopsy often has multiple etiologies, especially in patients with lymphomas. Pathological neuronal mechanisms integrate with an overproduction of IL-6, TNF-α, IL1-β by macrophages and monocytes, which amplifies inflammation and pain. In consideration of this complex pathogenesis, international guidelines recommend diversified analgesia protocols: thoracic epidural, paravertebral block, and systemic administration of opioids. Read More

View Article and Full-Text PDF

Soluble sST2 biomarker analysis for fibrosis development in atrial fibrillation. A case control study.

Clin Ter 2021 Mar;172(2):145-150

Emergency Department, Policlinico Umberto I Hospital, Sapienza University, Rome.

Abstract: Objectives. Atrial fibrillation (AF) is a clinically relevant supra-ventricular arrhythmia which represents an independent risk factor for development of heart failure and ischemic stroke. The present study aims at the investigation of the possible clinical role of the soluble sST2 biomarker to evaluate the fibrosis in a group of patients with first diagnosed or permanent AF. Read More

View Article and Full-Text PDF

Acute pulmonary hypertension and short-term outcomes in severe Covid-19 patients needing intensive care.

Acta Anaesthesiol Scand 2021 Jul 27;65(6):761-769. Epub 2021 Mar 27.

Department of Physiology and Pharmacology, Section of Anaesthesiology and Intensive Care, Karolinska Institutet, Stockholm, Sweden.

Introduction: Critically ill Covid-19 pneumonia patients are likely to develop the sequence of acute pulmonary hypertension, right ventricular (RV) strain, and eventually RV failure due to known pathophysiology (endothelial inflammation plus thrombo-embolism) that promotes increased pulmonary vascular resistance and pulmonary artery pressure. This study aimed to investigate the occurrence of acute pulmonary hypertension (aPH) as per established trans-thoracic echocardiography (TTE) criteria in Covid-19 patients receiving intensive care and to explore whether short-term outcomes are affected by the presence of aPH.

Methods: Medical records were reviewed for patients treated in the intensive care units at a tertiary university hospital over a month. Read More

View Article and Full-Text PDF

Comparison of right ventricular outflow tract gradient under anesthesia with post-operative gradient in patients undergoing tetralogy of Fallot repair.

Ann Pediatr Cardiol 2021 Jan-Mar;14(1):18-25. Epub 2020 Oct 19.

Department of Cardiothoracic and Vascular Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Intra-cardiac repair for tetralogy of Fallot has some degree of residual right ventricular outflow tract (RVOT) obstruction. However, the measurement of this gradient intra-operatively might get affected by the depth of anesthesia which is important for the long-term outcome.

Aims: The primary aim was to compare intraoperative RVOT gradient post repair under two different anesthetic depths of 1% and 2% end-tidal sevoflurane. Read More

View Article and Full-Text PDF
October 2020

The role of trans-thoracic echocardiography in the assessment of aortic annular diameter.

Medicine (Baltimore) 2021 Mar;100(9):e24682

Faculty of Medicine, Al-Azhar University, Damietta.

Abstract: We aimed to compare two-dimension transthoracic echocardiogram (2D-TTE) and three-dimension transthoracic echocardiogram (3D-TTE) measurements of the aortic annular diameter using multi-detector CT (MDCT) as a gold standard.This prospective observational study included 50 consecutive patients who came to the cardiology department, Al-Azhar University Hospital, New Damietta, for MDCT coronary angiography. The study was carried out in the period from July 2016 until February 2017. Read More

View Article and Full-Text PDF

Pulmonary vasodilation by sildenafil in acute intermediate-high risk pulmonary embolism: a randomized explorative trial.

BMC Pulm Med 2021 Feb 28;21(1):72. Epub 2021 Feb 28.

Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.

Background: To investigate if acute pulmonary vasodilation by sildenafil improves right ventricular function in patients with acute intermediate-high risk pulmonary embolism (PE).

Methods: Single center, explorative trial. Patients with PE were randomized to a single oral dose of sildenafil 50 mg (n = 10) or placebo (n = 10) as add-on to conventional therapy. Read More

View Article and Full-Text PDF
February 2021

Left atrial structural and functional remodeling following balloon mitral valvuloplasty.

Int J Cardiovasc Imaging 2021 Mar 19;37(3):999-1007. Epub 2020 Nov 19.

Department of Cardiothoracic Surgery, Aswan Heart Centre, Aswan, Egypt.

Mitral stenosis (MS) is associated with left atrial (LA) functional and morphological changes as a result of chronic increase in LA pressure. Relieving the mitral obstruction via balloon mitral valvuloplasty (BMV) might be associated with LA structural and functional remodeling. To study alterations of LA volume and functions 1 year following successful BMV in patients with isolated rheumatic severe mitral stenosis. Read More

View Article and Full-Text PDF

Comparison of flow-independent parameters for grading severity of aortic stenosis using intraoperative transesophageal echocardiography - A prospective observational study.

Ann Card Anaesth 2020 Oct-Dec;23(4):425-428

Department of Cardiac Anesthesia, AIIMS, Ansari Nagar, New Delhi, India.

Introduction: Discrepancies have been reported in grading of severity of aortic stenosis. We propose to compare Aortic valve area by continuity equation, Dimensionless Index and Acceleration time/Ejection time in patients with documented severe aortic stenosis with normal left ventricular function by TEE after induction of anesthesia. This might give use insight about the best parameter we can rely on intra-operatively for decision making. Read More

View Article and Full-Text PDF
October 2020

Hemodynamic Profiles of Cardiogenic Shock Depending on Their Etiology.

J Clin Med 2020 Oct 22;9(11). Epub 2020 Oct 22.

Cardiology Department, APHM, Mediterranean Association for Research and Studies in Cardiology (MARS Cardio), Centre for CardioVascular and Nutrition Research (C2VN), Aix-Marseille Univ, INSERM 1263, INRA 1260, Hopital Nord, 13015 Marseille, France.

The pathophysiology of cardiogenic shock (CS) varies depending on its etiology, which may lead to different hemodynamic profiles (HP) and may help tailor therapy. We aimed to assess the HP of CS patients according to their etiologies of acute myocardial infarction (AMI) and acute decompensated chronic heart failure (ADCHF). We included patients admitted for CS secondary to ADCHF and AMI. Read More

View Article and Full-Text PDF
October 2020

Association of Pulmonary Hypertension With End-Stage Renal Disease Among the Obese Population.

Cureus 2020 Aug 13;12(8):e9722. Epub 2020 Aug 13.

Orthopaedics, Jinnah Postgraduate Medical Center, Karachi, PAK.

Introduction Pulmonary hypertension (PH) is a known complication that occurs in patients of end-stage renal disease (ESRD) that have an arteriovenous fistula (AVF) for hemodialysis (HD). It is defined as pulmonary artery pressure (PAP) of greater than 30 mmHg on echocardiography. The presence of PH in ESRD is an independent risk factor and decreases the survival likelihood among HD patients. Read More

View Article and Full-Text PDF

The 90% effective dose of intranasal dexmedetomidine for procedural sedation in children with congenital heart disease before and after surgery: A biased-coin design up-and-down sequential allocation trial.

Acta Anaesthesiol Scand 2021 02 17;65(2):188-194. Epub 2020 Sep 17.

Department of Anesthesiology, Children's Hospital of Chongqing Medical University, Chongqing, China.

Background: Intranasal dexmedetomidine can provide adequate sedation during short procedures. However, there are few reports investigating the effective dose of intranasal dexmedetomidine for sedation in children with congenital heart disease (CHD) before and after surgery.

Methods: Children aged 13-36 months with acyanotic CHD requiring trans-thoracic echocardiography before cardiac surgery were recruited for this study. Read More

View Article and Full-Text PDF
February 2021

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction.

PLoS One 2020 9;15(7):e0232507. Epub 2020 Jul 9.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, United States of America.

Sex-related differences in cardiovascular diseases are highly complex in humans and model-dependent in experimental laboratory animals. The objective of this work was to comprehensively investigate key sex differences in the response to acute and prolonged adrenergic stimulation in C57Bl/6NCrl mice. Cardiac function was assessed by trans-thoracic echocardiography before and after acute adrenergic stimulation (a single sub-cutaneous dose of isoproterenol 10 mg/kg) in 15 weeks old male and female C57Bl/6NCrl mice. Read More

View Article and Full-Text PDF
September 2020

Beneficial effects of DAAs on cardiac function and structure in hepatitis C patients with low-moderate liver fibrosis.

J Viral Hepat 2020 11 13;27(11):1214-1221. Epub 2020 Aug 13.

Division of General Medicine and Hypertension, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

Hepatitis C virus (HCV)-related chronic infection has been associated with a higher incidence of cardiovascular diseases. An altered morphology and function of both left and right heart have been described in HCV patients; however, the causality of the association is still debated. Ninety-eight nonobese and nondiabetic HCV patients (59. Read More

View Article and Full-Text PDF
November 2020

Higher serum angiopoietin 2 levels are independently associated with coronary microvascular dysfunction in patients with angina in the absence of obstructive coronary artery disease.

Chin Med J (Engl) 2020 Jul;133(14):1662-1668

Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital; Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health; Key Laboratory of Molecular Cardiovascular Science, Ministry of Education; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.

Background: Angiopoietin-2 (Ang-2) is a type of endothelial growth factor involved in angiogenesis and vascular remodeling. Circulating Ang-2 levels are elevated in patients with obstructive coronary artery disease (CAD). This study aimed to evaluate the association between serum Ang-2 levels and coronary microvascular dysfunction in patients without obstructive CAD. Read More

View Article and Full-Text PDF

Myocardial work is a predictor of exercise tolerance in patients with dilated cardiomyopathy and left ventricular dyssynchrony.

Int J Cardiovasc Imaging 2020 Jan 12;36(1):45-53. Epub 2019 Sep 12.

CHU Rennes, Inserm, LTSI - UMR 1099, University of Rennes, 35000, Rennes, France.

The assessment of myocardial work (MW) by pressure-strain loops is a recently introduced tool for the assessment of myocardial performance. Aim of the present study is to evaluate the relationship between myocardial work and exercise tolerance in patients with dilated cardiomyopathy (DCM). 51 patients with DCM (mean age 57 ± 13 years, left ventricular ejection fraction: 32 ± 9%) underwent cardiopulmonary exercise test (CPET) to assess exercise performance. Read More

View Article and Full-Text PDF
January 2020

Effect of human thymus adipose tissue-derived mesenchymal stem cells on myocardial infarction in rat model.

Regen Ther 2019 Dec 8;11:192-198. Epub 2019 Aug 8.

Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.

Background And Objective: Stem cell (SC) therapy exhibits promising therapeutic efficiency against cardiovascular disease. The thymus adipose tissue (TAT) is familiar to cardiac surgeons with sternotomy; however, the application of TAT in SC therapy remains unknown. We assessed the effectiveness of TAT-derived mesenchymal SCs (TAT-MSCs) in the rat myocardial infarction (MI) model. Read More

View Article and Full-Text PDF
December 2019

Right Ventricle Function in Patients with Acute Coronary Syndrome and Concomitant Undiagnosed Chronic Obstructive Pulmonary Disease.

COPD 2019 08 29;16(3-4):284-291. Epub 2019 Jul 29.

Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara , Cona , Italy.

Chronic obstructive pulmonary disease (COPD) is frequently undiagnosed in patients with ischemic heart disease. Nowadays, it is still unknown whether undiagnosed concomitant COPD is related to early structural changes of the heart, as detectable by trans-thoracic echocardiography (TTE). Starting from the study population of the Screening for COPD in ACS Patients (SCAP) trial, we sought to investigate potential differences in echocardiographic parameters in patients with acute coronary syndromes (ACS), with or without undiagnosed concomitant COPD. Read More

View Article and Full-Text PDF

The Relationship Between Visceral Adiposity Index and Epicardial Adipose Tissue in Patients with Type 2 Diabetes Mellitus.

Exp Clin Endocrinol Diabetes 2021 May 6;129(5):390-395. Epub 2019 May 6.

Department of Endocrinology, Erzincan University, Mengucek Gazi Training and Research Hospital, Turkey.

Introduction And Aim: Cardiovascular diseases remain the most common cause of morbidity and mortality in patients with diabetes. Epicardial adipose tissue (EAT), visceral fat depot of the heart, was found to be associated with coronary artery disease in cardiac and non-cardiac patients. Increased visceral adiposity is associated with proinflammatory activity, impaired insulin sensitivity, increased risk of atherosclerosis and high mortality. Read More

View Article and Full-Text PDF

Automatic Estimation of Coronary Blood Flow Velocity Step 1 for Developing a Tool to Diagnose Patients With Micro-Vascular Angina Pectoris.

Front Cardiovasc Med 2019 22;6. Epub 2019 Jan 22.

Stavanger University Hospital Department of Cardiology, Stavanger, Norway.

Our aim was to automatically estimate the blood velocity in coronary arteries using cine X-ray angiographic sequence. Estimating the coronary blood velocity is a key approach in investigating patients with angina pectoris and no significant coronary artery disease. Blood velocity estimation is central in assessing coronary flow reserve. Read More

View Article and Full-Text PDF
January 2019

Could vitamin D deficiency influence left heart ventricular geometry in youngsters with type 1 diabetes mellitus?

Hippokratia 2019 Jan-Mar;23(1):9-14

4 Department of Paediatrics, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece.

Background: Experimental and clinical studies have shown the cardio-protective, anti-inflammatory, and anti-atherosclerotic actions of vitamin D.

Material And Methods: We aimed to investigate a possible correlation between vitamin D status and heart geometry using echocardiographic parameters of the left ventricle in youngsters with type 1 diabetes mellitus (T1D). Seventy-eight pediatric patients (aged 13. Read More

View Article and Full-Text PDF

Epicardial fat thickness can predict severity and multivessel distribution in Egyptian patients with atherosclerotic coronary artery stenosis.

Egypt Heart J 2018 Dec 1;70(4):323-327. Epub 2018 May 1.

Cardiology Department, Al-Zaitoun Specialized Hospital, Egypt.

Background: Epicardial fat, in addition to its secretory function, may have an important role in predicting and stratifying cardiovascular risk. There is a paucity of data regarding correlation between epicardial fat thickness and coronary artery disease in Egypt.

Aim Of The Study: To study the relationship between epicardial fat thickness (EFT) measured by trans-thoracic echocardiography (TTE) and severity of coronary artery disease (CAD) and its distribution in Egyptian population. Read More

View Article and Full-Text PDF
December 2018

Board examination stress effect on diastolic function.

J Clin Ultrasound 2019 Mar 12;47(3):139-143. Epub 2018 Nov 12.

Cardiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Background: To this date, effects of mental stress on cardiac function have not been clearly investigated. Although hemodynamic and neuroendocrine adverse effects of daily mental stress on cardiovascular morbidity and mortality have been reported, its direct impact on diastolic function of the heart has not been previously studied. In this study, we aimed to assess the role of Board Exam anxiety on right and left ventricular diastolic function in medical residents. Read More

View Article and Full-Text PDF

Evaluation of Myocardial Injury using Standard Diagnostic Tools and Tissue Doppler Imaging in Blunt Trauma Chest.

J Clin Diagn Res 2017 Jun 1;11(6):OC33-OC36. Epub 2017 Jun 1.

Intern, Department of Surgery, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Introduction: Myocardial contusion is an entity in chest trauma which is difficult to diagnose. Current practice relies more on cardiac-specific biochemical markers and standard echocardiography, but no gold standard test exists. The application of Tissue Doppler imaging is yet unexplored. Read More

View Article and Full-Text PDF

Preoperative evaluation of anomalous pulmonary venous connection using dual-source computed tomography: Comparison with echocardiography.

Eur J Radiol 2017 Sep 21;94:107-114. Epub 2017 Jun 21.

Department of Radiology, West China Second University Hospital, Sichuan University, 20# Section 3 South Renmin Road, Chengdu, Sichuan 610041, China. Electronic address:

Purpose: To evaluate the image features and diagnostic agreement for anomalous pulmonary venous connection (APVC) by dual-source computed tomography (DSCT) before surgery when compared with trans-thoracic echocardiography (TTE).

Materials And Methods: A total of one hundred and twenty-three patients were enrolled in this study. The associated malformation was analyzed between 39 total anomalous pulmonary venous connections (TAPVC) and 84 partial anomalous pulmonary venous connections (PAPVC). Read More

View Article and Full-Text PDF
September 2017

Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice.

Biol Sex Differ 2017 7;8. Epub 2017 Jan 7.

Department of Experimental and Clinical Pharmacology, University of Minnesota, 308 Harvard St S.E, Minneapolis, MN 55455 USA.

Background: There is inconclusive evidence about the role of sex as a risk factor for doxorubicin (DOX)-induced cardiotoxicity. Recent experimental studies have shown that adult female rats are protected against DOX-induced cardiotoxicity. However, the mechanisms of this sexual dimorphism are not fully elucidated. Read More

View Article and Full-Text PDF

Non-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes.

Europace 2016 Dec;18(suppl 4):iv104-iv112

Department of Bioengineering, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA 92093-0412, USA

Aims: Left ventricular activation delay due to left bundle branch block (LBBB) is an important determinant of the severity of dyssynchronous heart failure (DHF). We investigated whether patient-specific computational models constructed from non-invasive measurements can provide measures of baseline dyssynchrony and its reduction after CRT that may explain the degree of long-term reverse ventricular remodelling.

Methods And Results: LV end-systolic volume reduction (ΔESV) measured by 2D trans-thoracic echocardiography in eight patients following 6 months of CRT was significantly (P < 0. Read More

View Article and Full-Text PDF
December 2016

The Effect of Metformin on Diastolic Function in Patients Presenting with ST-Elevation Myocardial Infarction.

PLoS One 2016 15;11(12):e0168340. Epub 2016 Dec 15.

Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Introduction: Diastolic dysfunction is an important predictor of poor outcome after myocardial infarction. Metformin treatment improved diastolic function in animal models and patients with diabetes. Whether metformin improves diastolic function in patients presenting with ST-segment elevation myocardial infarction (STEMI) is unknown. Read More

View Article and Full-Text PDF

Do mathematical model studies settle the controversy on the origin of cardiac synchronous trans-thoracic electrical impedance variations? A systematic review.

Physiol Meas 2016 09 17;37(9):R88-R108. Epub 2016 Aug 17.

VU University, Faculty of Science, Amsterdam, The Netherlands. Department of Physics and Medical Technology, VU University Medical Centre, Amsterdam, The Netherlands.

Impedance cardiography (ICG) is a method to evaluate cardiac-stroke volume and cardiac-output by measuring the cardiac-synchronous changes in the dynamic trans-thoracic electrical impedance (ΔZ). Clinical evaluations on the accuracy of ICG showed varying results. Consequently, the classic assumption in ICG-the aorta as a main source of ΔZ-is questioned and subsequently investigated in simulation studies using mathematical models of the electrical resistivity of the human body. Read More

View Article and Full-Text PDF
September 2016

[Combination of B-type brain natriuretic peptide with left ventricular diastolic dysfunction for prediction of mortality in the patients with septic shock].

Zhonghua Yi Xue Za Zhi 2016 Aug;96(29):2295-300

Intensive Care Unit, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.

Objective: To evaluate the prognostic value of combination of plasma brain natriuretic peptide(BNP) with the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity(E/E') in the patients with septic shock.

Methods: From June 2012 to December 2013 , 127 patients with septic shock were consecutively recruited and underwent trans-thoracic echocardiography examination within 6 h after admission to Intensive Care Unit(ICU), Zhejiang Provincial People's Hospital. Plasma BNP concentration was measured using ELISA method. Read More

View Article and Full-Text PDF