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Conventional and high resolution chemical characterization to assess refinery effluent treatment performance.

Chemosphere 2021 Mar 27;278:130383. Epub 2021 Mar 27.

Concawe, Boulevard du Souverain 165, 1160, Brussels, Belgium.

Refinery effluents represent an emission source of hydrocarbons (HCs) and other constituents to the environment. Thus, characterisation of effluent quality in terms of concentrations of key parameters relative to permitted standards is important and for total petroleum hydrocarbons (TPH), the specific composition of the HC mixture can affect its toxicity to aquatic organisms. Therefore, this study was designed to analyse TPH, benzene, toluene, ethyl benzene, xylenes (BTEX), polycyclic aromatic hydrocarbons (PAHs), (bio) chemical oxygen demand, total nitrogen, total suspended solids and selected metals before, and after, treatment steps to demonstrate removal efficiencies across 13 refineries with variable wastewater treatment systems. Read More

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Long-term results of Sauvé-Kapandji procedure.

J Hand Surg Eur Vol 2021 Apr 12:17531934211004459. Epub 2021 Apr 12.

Department of Orthopedics, Hand Surgery Division, Balgrist University Hospital Zurich, Switzerland.

The Sauvé-Kapandji procedure is an established treatment option for distal radioulnar joint dysfunction. We retrospectively analysed 36 patients following Sauvé-Kapandji procedure between 1997 and 2013. Fifteen patients were available for a follow-up after a mean of 13 years (range 6 to 23). Read More

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Effectiveness of Targeted Interventions on Treatment of Infants With Bronchiolitis: A Randomized Clinical Trial.

JAMA Pediatr 2021 Apr 12. Epub 2021 Apr 12.

Children's Emergency Department, Starship Children's Hospital, Auckland, New Zealand.

Importance: In developed countries, bronchiolitis is the most common reason for infants to be admitted to the hospital, and all international bronchiolitis guidelines recommend supportive care; however, significant variation in practice continues with infants receiving non-evidence-based therapies. Deimplementation research aims to reduce the use of low-value care, and advancing science in this area is critical to delivering evidence-based care.

Objective: To determine the effectiveness of targeted interventions vs passive dissemination of an evidence-based bronchiolitis guideline in improving treatment of infants with bronchiolitis. Read More

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Clozapine-Associated Leukopenia and Agranulocytosis in Western Cape, South Africa: A 3-Year Retrospective Cohort Study.

J Clin Psychopharmacol 2021 Apr 8. Epub 2021 Apr 8.

From the Division of Clinical Pharmacology, Department of Medicine Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University Computational Biology Division, Integrative Biomedical Sciences Wellcome Centre for Infectious Disease Research in Africa, Institute of Infectious Diseases and Molecular Medicine Centre for Infectious Disease Epidemiology Research, School of Public Health and Family Medicine, University of Cape Town Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Background: Clozapine may cause life-threatening hematological side effects (HSEs). Hematological side effect incidence data from Sub-Saharan Africa are lacking. Furthermore, clozapine reduces cellular immunity, and it is unknown whether clozapine is a risk factor for tuberculosis or whether HIV is a risk factor for developing HSEs. Read More

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Radiological measurement of cochlear dimensions in cochlear hypoplasia and its effect on cochlear implant selection.

J Laryngol Otol 2021 Apr 12:1-7. Epub 2021 Apr 12.

Department of Otorhinolaryngology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Objective: To determine the effect of cochlear dimensions on cochlear implant selection in cochlear hypoplasia patients.

Methods: Temporal bone computed tomography images of 36 patients diagnosed with cochlear hypoplasia between 2010 and 2016 were retrospectively reviewed and compared with those of 40 controls without sensorineural hearing loss.

Results: Basal turn length and mid-modiolar height were significantly lower in the cochlear hypoplasia patients with subtypes I, II and III than in the control group (p < 0. Read More

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Nutritional, physical and sensory characteristics of gluten-free biscuits incorporated with a novel resistant starch ingredient.

Heliyon 2021 Mar 21;7(3):e06562. Epub 2021 Mar 21.

Department for Sustainable Food Process (DiSTAS), Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122, Piacenza, Italy.

Gluten-free (GF) biscuits were prepared by replacing part of a GF flour mix (GFM) with 0, 15, 30 and 45 g/100 g (total flour) with a novel resistant starch-rich ingredient obtained from annealed white sorghum starch (RSWS). The chemical composition, physical characteristics, in vitro starch digestion and sensory evaluation of biscuits were considered. The chemical composition of samples was influenced by the addition of the RSWS. Read More

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Properties of Mucoid Serotype 3 From Children in China.

Front Cell Infect Microbiol 2021 24;11:648040. Epub 2021 Mar 24.

Department of Microbiology, Beijing Children's Hospital, Capital Medical University, Beijing, China.

Objective: To investigate the characteristics of hosts, antimicrobial susceptibility, and molecular epidemiology of mucoid serotype 3 () isolated from children in China.

Method: isolates collected between January 2016 and December 2019 were analyzed. isolates with mucoid phenotype were selected visually, and serotype 3 isolates were confirmed by Quellung reaction. Read More

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Evaluation of olive oil effects on human stress response by measuring cerebral blood flow.

Food Sci Nutr 2021 Apr 16;9(4):1851-1859. Epub 2021 Feb 16.

Department of Neuropsychiatry Keio University School of Medicine Tokyo Japan.

In this paper, we evaluated the effects of olive oil on human's stress level. In recent years, mental stress from harsh working environment have been causing serious problems to human health, both mentally and physically. Symptoms of stress may include feelings of worthlessness, agitation, anxiety, lethargy, insomnia, and behavioral changes. Read More

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Immediate three-dimensional changes in the oropharynx after different mandibular advancements in counterclockwise rotation orthognathic planning.

J Clin Exp Dent 2021 Apr 1;13(4):e334-e341. Epub 2021 Apr 1.

Department of Dental Clinic of Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.

Background: A retrospective cohort study was performed to evaluate the immediate effect on the oropharynx dimensions from different mandibular advancements in patients undergone counterclockwise rotation (CCW) of the maxillomandibular complex.

Material And Methods: 138 CBCT images of patients, who had undergone orthognathic surgery, were identified from Dolphin Imaging archive according to pre- (T0) and post-operative (T1) times. Each pre-operative CBCT image was selected considering retrognathic mandible. Read More

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Clinical significance of T lymphocyte subsets, immunoglobulin and complement expression in peripheral blood of children with steroid-dependent nephrotic syndrome/frequently relapsing nephrotic syndrome.

Am J Transl Res 2021 15;13(3):1890-1895. Epub 2021 Mar 15.

Department of Pediatrics, Quanzhou First Hospital Affiliated to Fujian Medical University Quanzhou, Fujian Province, China.

Objective: To investigate the clinical significance of T lymphocyte subsets, immunoglobulin and complement expression in the peripheral blood of children with steroid-dependent nephrotic syndrome/frequently relapsing nephrotic syndrome (SDNS/FRNS).

Methods: A prospective study was conducted on 285 children with nephrotic syndrome (NS). Among the 285 patients, 187 children had steroid-sensitive nephrotic syndrome (SSNS) and 98 children had SDNS/FRNS according to their sensitivity to hormones. Read More

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Immunomodulatory function of the active ingredients in traditional Chinese prescriptions on early stage esophageal cancer with dysplasia.

Am J Transl Res 2021 15;13(3):1667-1675. Epub 2021 Mar 15.

Department of TCM, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu Province, China.

Objective: To explore the effects of the ingredients in a traditional Chinese prescription on the immune regulation of esophageal cancer in patients with early atypical hyperplasia.

Methods: A total of 60 C57BL mice were randomly selected as the positive control group; another 240 C57BL mice were randomly divided into a blank control group (n=30), a 4NQO group (n=60) and an experimental group (n=120). The experimental group was divided into the prevention group which received carcinogens and the prescription composition simultaneously, and the treatment group which received carcinogens first and the prescription composition second. Read More

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Six Weeks of Basketball Combined With Mathematics in Physical Education Classes Can Improve Children's Motivation for Mathematics.

Front Psychol 2021 26;12:636578. Epub 2021 Mar 26.

Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.

This study investigated whether 6 weeks of basketball combined with mathematics once a week in physical education lessons could improve children's motivation for mathematics. Seven hundred fifty-seven children (mean age = 10.4 years, age range: 7-12 years) were randomly selected to have either basketball combined with mathematics once a week (BM) or to have basketball sessions without mathematics (CON). Read More

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Long-term color stability of light-polymerized resin luting agents in different beverages.

J Prosthodont Res 2021 Apr 9. Epub 2021 Apr 9.

Department of Crown and Bridge, School of Life Dentistry at Tokyo, The Nippon Dental University, 1-9-20 Fujimi, Chiyoda-ku, Tokyo.

Purpose: The purpose of this study was to evaluate the long-term color stability of light-polymerized resin luting agents stored in different beverages.

Methods: Eleven shades of two light-polymerized resin luting agents, Choice2 (A1, A2, B1, TRANSLUCENT, MILKY OPAQUE, and MILKY BRIGHT) and BeautiCem Veneer (H-Value, M-Value, L-Value, Ivory-D, Ivory-L) were selected in this study. Disk-shaped specimens were fabricated with 1. Read More

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2-Minute Tidal Breathing Methacholine Bronchial Challenge: Comparison of Two Jet Nebulizers.

Clin Respir J 2021 Apr 11. Epub 2021 Apr 11.

Guangzhou Institute of Respiratory Health, State Key Lab of Respiratory Disease, The first affiliated hospital of Guangzhou Medical University, Guangzhou, China.

Background: The American Thoracic Society (ATS) guideline for methacholine challenge testing (MCT) recommended using the English Wright (EW) nebulizer. However, other brands of nebulizers are also indicated to be acceptable for this technique, but further validation of nebulizer performance is recommended.

Objective: To compare the methacholine provocation concentration causing a 20% fall in forced expiratory volume in 1 second (PC -FEV ) measured by using EW nebulizer and DV 646 nebulizer. Read More

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Association between impulsivity and orthorexia nervosa: any moderating role of maladaptive personality traits?

Eat Weight Disord 2021 Apr 11. Epub 2021 Apr 11.

INSPECT-LB, National Institute of Public Health, Clinical Epidemiology and Toxicology, Beirut, Lebanon.

Objectives: To explore the possible moderating relation between impulsive behavior and maladaptive personality traits in regards to orthorexia nervosa (ON).

Methods: This cross-sectional study was conducted between July and December 2019 and recruited 519 Lebanese adults from seven community pharmacies randomly selected from a list provided by the Lebanese Order of Pharmacists. The Teruel Orthorexia Scale (TOS) was employed to assess orthorexic eating tendencies, the I-8 measured impulsivity and the Personality Inventory for DSM-5 (PID) evaluated maladaptive personality traits. Read More

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Patient's Clinical Presentation and CPPopt Availability: Any Association?

Acta Neurochir Suppl 2021 ;131:167-172

Department of Intensive Care, University Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

Background: The 'optimal' CPP (CPPopt) concept is based on the vascular pressure reactivity index (PRx). The feasibility and effectiveness of CPPopt guided therapy in severe traumatic brain injury (TBI) patients is currently being investigated prospectively in the COGiTATE trial. At the moment there is no clear evidence that certain admission and treatment characteristics are associated with CPPopt availability (yield). Read More

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January 2021

Haemorrhoidal haemodynamic changes in patients with haemorrhoids treated using Doppler-guided dearterialization.

BJS Open 2021 Mar;5(2)

Proctology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Rome, Italy.

Background: Arterial hyperflow to haemorrhoids has been implicated as a possible pathophysiological co-factor in haemorrhoidal disease. The purpose of this study was to investigate how transanal haemorrhoidal dearterialization (THD) can influence haemodynamic parameters at the level of the haemorrhoidal piles.

Methods: Patients with grade III haemorrhoids selected for THD between July and December 2018 were evaluated using endoanal ultrasonography and colour Doppler imaging at the level of internal haemorrhoids before and 1 year after the surgical procedure. Read More

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Influence of silymarin components on keratinocytes and 3D reconstructed epidermis.

Toxicol In Vitro 2021 Apr 8:105162. Epub 2021 Apr 8.

Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Hněvotínská 3, 775 15 Olomouc, Czech Republic.

Silymarin is a flavonoid complex isolated from the plant Silybum marianum which is well known for its antioxidant, hepatoprotective and immunomodulatory effects. Since little is known about its anti-inflammatory properties and healing effects, our study focused on whether or not silymarin components reduce inflammation and support epidermis regeneration. Lipopolysaccharides (LPS) and sodium dodecyl sulfate (SDS) were used to induce inflammation in normal human epidermal keratinocytes (NHEKs) and reconstructed epidermis (RHE), respectively. Read More

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Indoor air quality of 5,000 households and its determinants. Part B: Volatile organic compounds and inorganic gaseous pollutants in the Japan Environment and Children's Study.

Environ Res 2021 Apr 8:111135. Epub 2021 Apr 8.

Japan Environment and Children's Study Programme Office, Centre for Health and Environmental Risk Research, National Institute for Environmental Studies, Tsukuba, Japan. Electronic address:

Volatile organic compounds (VOCs) are major indoor air pollutants. Quantification of indoor concentrations of VOCs and identification of factors associated with these concentrations can help manage indoor air quality. This study measured the concentrations of VOCs and inorganic gaseous pollutants in around 5,000 households in Japan and utilised a random forest model to estimate these concentrations and identify important determinants. Read More

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Towards Improving the Prediction of Functional Ambulation after Spinal Cord Injury Though the Inclusion of Limb Accelerations During Sleep and Personal Factors.

Arch Phys Med Rehabil 2021 Apr 8. Epub 2021 Apr 8.

Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh PA; Human Engineering Research Laboratories, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA; Department of Bioengineering; Physical Medicine and Rehabilitation; Physical Therapy, University of Pittsburgh, Pittsburgh, PA. Electronic address:

Objective: To determine if functional measures of ambulation can be accurately classified using clinical measures, demographics, personal, psychosocial, and environmental factors (PPEF), and limb accelerations (LA) obtained during sleep, among individuals with chronic, motor incomplete spinal cord injury (SCI) in an effort to guide future, longitudinal predictions models.

Design: Cross-sectional, 1-5 days of data collection SETTING: Community-based data collection PARTICIPANTS: Adults with chronic (>1 year), motor incomplete SCI (n=27) INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: Ambulatory ability based on the 10-Meter (10mWT) or 6-Minute Walk Tests (6MWT) categorized as non-ambulatory, household ambulator (0.01-0. Read More

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Combining inhibitors of Brd4 and cyclin-dependent kinase can decrease tumor growth in neuroblastoma with MYCN amplification.

J Pediatr Surg 2021 Mar 26:60215. Epub 2021 Mar 26.

Department of Surgery, Stanford University, Stanford, CA, USA. Electronic address:

Introduction: High-risk neuroblastoma is a deadly disease; poor prognosticators are MYCN-amplification and TERT-overexpression. We hypothesized that Gene Set Enrichment Analysis (GSEA) could identify pathways associated with MYCN-amplification and that inhibition of these pathways could decrease tumor growth.

Methods: We analyzed the Neuroblastoma-Kocak dataset (GSE45547, n = 649) and identified pathways associated with MYCN-amplification. Read More

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Updating analysis of nitrogen balance experiments in dairy cows.

J Dairy Sci 2021 Apr 7. Epub 2021 Apr 7.

Department of Animal Nutrition and Biotechnology, and Fisheries, University of Agriculture in Krakow, Krakow 30059, Poland.

Nitrogen balance (NB) experiments allow calculation of N retention in the body by subtracting N excreted in feces (NF), urine (NU) and milk (NM) from N intake (NI). In a previous study, we found that NB data from experiments with lactating dairy cows were generally high and, in the current meta-analysis, we update our earlier study with experiments from the last 2 decades and investigate probable causes of error. A total of 83 publications, with 86 experiments and 307 dietary treatments, were selected from top-ranked scientific journals that reported all NB components. Read More

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Supporting Parents & Kids Through Lockdown Experiences (SPARKLE): A digital parenting support app implemented in an ongoing general population cohort study during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial.

Trials 2021 Apr 10;22(1):267. Epub 2021 Apr 10.

Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Objectives: The COVID-19 related lockdowns and distancing measures have presented families with unprecedented challenges. A UK-wide cohort study tracking changes in families' mental health since early lockdown (Co-SPACE) found a significant rise in primary school-aged children's behaviour problems and associated family-related stress. Three-quarters of parents in Co-SPACE also reported wanting extra support. Read More

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Trunk kinematics and muscle activation patterns during stand-to-sit movement and the relationship with postural stability in aging.

Gait Posture 2021 Mar 24;86:292-298. Epub 2021 Mar 24.

University of Maryland School of Medicine, Department of Physical Therapy & Rehabilitation Science, Baltimore, MD, 21201, United States. Electronic address:

Background: Stand-to-sit (StandTS) movement is an important functional activity that can be challenging for older adults due to age-related changes in neuromotor control. Although trunk flexion, eccentric contraction of the rectus femoris (RF), and coordination of RF and biceps femoris (BF) muscles are important to the StandTS task, the effects of aging on these and related outcomes are not well studied.

Research Question: What are the age-related differences in trunk flexion, lower extremity muscle activation patterns, and postural stability during a StandTS task and what is the relationship between these variables?

Methods: Ten younger and ten older healthy adults performed three StandTS trials at self-selected speeds. Read More

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Impacts of vegetation on particle concentrations in roadside environments.

Environ Pollut 2021 Apr 1;282:117067. Epub 2021 Apr 1.

International Center for Adaptation Planning and Design, College of Design, Construction and Planning, University of Florida, PO Box 115706, Gainesville, FL, 32611-5706, USA. Electronic address:

In roadside environments, commuters are exposed to a high level of traffic-related pollution. Despite vegetation is often used to mitigate air pollution in road environments, its air quality impacts are complex and could be both positive or negative depending on specific conditions. This study conducted field measurements to assess the air quality impacts of roadside vegetation. Read More

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Does the Surgical Intervention for Trigeminal Neuralgia Refractory to Pharmacotherapy Improve Quality-of-Life? - A Systematic Review.

J Oral Maxillofac Surg 2021 Mar 10. Epub 2021 Mar 10.

Senior Resident, Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Purpose: Trigeminal neuralgia (TN) refractory to pharmacotherapy requires surgical interventions which vary from percutaneous procedure to microvascular decompression (MVD). The aim of the systematic review is to find evidence for the surgical treatment for TN with high success rate and low complications which improves the quality-of-life (QOL).

Methods: A systematic literature search was made on published studies from MEDLINE, SCOPUS, science direct, and Cochrane Library databases that report the available surgical treatment for TN up to March 2020 and studies referred in the selected papers. Read More

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Effectiveness and Safety of Moxibustion Robots on Primary Dysmenorrhea: A Randomized Controlled Pilot Trial.

Chin J Integr Med 2021 Apr 10. Epub 2021 Apr 10.

Department of Acupuncture and Rehabilitation, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

Objective: To conduct a pilot trial to explore the effectiveness and safety of moxibustion robots in treating primary dysmenorrhea (PD) and evaluate its feasibility in clinic.

Methods: A total of 70 participants with PD were allocated to either moxibustion robot (MR) group (35 cases) or manual moxibustion (MM) group (35 cases) using computer-generated randomization. One acupoint Guanyuan (CV 4) was selected to receive moxa heat stimulation. Read More

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Global diversity and biogeography of the mycobiome.

Appl Environ Microbiol 2021 Apr 9. Epub 2021 Apr 9.

Genome Center, University of California, Davis, CA, United States.

Seagrasses are marine flowering plants that provide critical ecosystem services in coastal environments worldwide. Marine fungi are often overlooked in microbiome and seagrass studies, despite terrestrial fungi having critical functional roles as decomposers, pathogens or endophytes in global ecosystems. Here we characterize the distribution of fungi associated with the seagrass, using leaves, roots, and rhizosphere sediment from 16 locations across its full biogeographic range. Read More

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Traumatic Spinal Injury: Preliminary Results of Respiratory Function, Voice and Quality of Life.

J Voice 2021 Apr 6. Epub 2021 Apr 6.

Adjunct Professor, Speech Therapy Course, Ceilândia Campus of the University of Brasilia; Department where the study was conducted: Ceilândia Campus of the University of Brasilia, Federal District, Brazil, Center for Voice Studies - CEV.

Objectives: Assess respiratory muscle strength, voice and the quality of life of patients with traumatic cervical and thoracic spinal cord injury.

Methods: Preliminary analytical case control study of 28 adult men, aged between 18 and 65 years, divided into two groups: a research group consisting of 14 patients with cervical and thoracic spinal cord injury, and control group (CG) with 14 noninjured individuals. The subjects had their maximum inspiratory and expiratory pressures measured, underwent voice handicap index-10 assessment, had their voices recorded for auditory perception analysis, using the voice deviation and GRBASI scales, and for acoustic analysis, based on extraction of the parameters selected and completed a quality-of-life questionnaire (WHOQOL-bref protocol). Read More

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Ethnic Specific body fat percent prediction equation as surrogate marker of obesity in Ethiopian adults.

J Health Popul Nutr 2021 Apr 9;40(1):17. Epub 2021 Apr 9.

Department of Nutrition and Dietetics, Faculty of Public Health, Institute of Health, Jimma University, Jimma, Ethiopia.

Background: Application of advanced body composition measurement methods is not practical in developing countries context due to cost and unavailability of facilities. This study generated ethnic specific body fat percent prediction equation for Ethiopian adults using appropriate data.

Methods: A cross-sectional study was carried ifrom February to April 2015 among 704 randomly selected adult employees of Jimma University. Read More

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