Langmuir 2021 04 14;37(16):4793-4801. Epub 2021 Apr 14.
Department of Information Science and Technology, George Mason University, Fairfax, Virginia 22030, United States.
Myelin basic protein (MBP), one of the major protein constituents of the myelin sheath, possesses unique ligand-binding features. We present a novel equilibrium headspace gas chromatographic technique to examine the thermodynamics of noncovalent interactions between common perfume components: Lilial, Hedione, Hexylcinnamic aldehyde, and Versalide with MBP monomers and its hexameric MBP-pseudophase. A general theoretical model is used to calculate the critical aggregation concentration (cac) of MBP, perfume component binding constants with monomeric MBP, , and MBP as pseudophase, , and free energies for perfume component binding with monomeric MBP, Δ, and MBP as pseudophase, Δ. Read More