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Self-referencing biosensors using Fano resonance in periodic aluminium nanostructures.

Nanoscale 2021 Sep 15. Epub 2021 Sep 15.

Research Center for Applied Sciences, Academia Sinica, Taipei 11529, Taiwan.

Surface plasmon resonance (SPR) is an important technique for real-time and label-free detection of specific binding biomolecules. However, conventional SPR signals come from both the surface binding biomolecules and the variation in the bulk refractive index. This work demonstrates that Fano resonance in an aluminum capped nanoslit array has the ability to remove the signal of bulk refractive index changes from the SPR signal. Read More

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September 2021

Effects of consumers and health providers working in partnership on health services planning, delivery and evaluation.

Cochrane Database Syst Rev 2021 Sep 15;9:CD013373. Epub 2021 Sep 15.

Centre for Health Communication and Participation, School of Psychology and Public Health, La Trobe University, Bundoora, Australia.

Background: Health services have traditionally been developed to focus on specific diseases or medical specialties. Involving consumers as partners in planning, delivering and evaluating health services may lead to services that are person-centred and so better able to meet the needs of and provide care for individuals. Globally, governments recommend consumer involvement in healthcare decision-making at the systems level, as a strategy for promoting person-centred health services. Read More

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September 2021

Comparison of Vestibular Depth Relapse and Wound Healing After Reconstructive Preprosthetic Surgery Using Cryopreserved Amniotic Membrane and Acellular Dermal Matrix - A Comparative Study.

Ann Maxillofac Surg 2021 Jan-Jun;11(1):12-16. Epub 2021 Jul 24.

Department of Oral and Maxillofacial Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: The significance of membranes as wound dressing in oral surgeries has been reported by previous studies. The aim of the present split-mouth randomized clinical study was to assess and compare the wound dressing properties of acellular dermal matrix (ADM) and cryopreserved human amniotic membrane (AM) after reconstructive preprosthetic oral surgery.

Materials And Methods: Twenty-eight patients with complete mandibular edentulism and resorbed alveolar bone were included. Read More

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Restored and remnant Banksia woodlands elicit different foraging behavior in avian pollinators.

Ecol Evol 2021 Sep 27;11(17):11774-11785. Epub 2021 Jul 27.

School of Biological Science The University of Western Australia Crawley WA Australia.

Pollinators and the pollination services they provide are critical for seed set and self-sustainability of most flowering plants. Despite this, pollinators are rarely assessed in restored plant communities, where their services are largely assumed to re-establish. Bird-pollinator richness, foraging, and interaction behavior were compared between natural and restored Banksia woodland sites in Western Australia to assess their re-establishment in restored sites. Read More

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September 2021

Atrial Fibrillation, Stroke, and Silent Cerebrovascular Disease: A Population-Based MRI Study.

Neurology 2021 Sep 14. Epub 2021 Sep 14.

Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg, Sweden.

Background And Objectives: Atrial fibrillation (AF) has been associated with cognitive decline and dementia. However, the mechanisms behind these associations are not clear. Examination of cerebrovascular pathology on MRI may shed light on how AF affects the brain. Read More

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September 2021

Characterization of Cycling in a Hoolock Gibbon (Hoolock leuconedys).

Folia Primatol (Basel) 2021 Sep 14:1-6. Epub 2021 Sep 14.

Department of Animal Behavior, Ecology, and Conservation, Canisius College, Buffalo, New York, USA.

Here we examine the patterns of reproductive hormones (progesterone and estrone-3 glucuronide, or E1G) in one female hoolock gibbon (Hoolock leuconedys) housed at the Gibbon Conservation Center, throughout the maturation period. Three hundred forty-five fecal samples were collected from the individual over a 5-year period (2012-2017) beginning at the age of 6 years and ending at the age of 11. The average measured progesterone concentration increased from 19. Read More

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September 2021

Five-Year Outcomes of Medical Management Alone for Adult Patients with Ischemic Moyamoya Disease without Cerebral Misery Perfusion.

Cerebrovasc Dis 2021 Sep 9:1-7. Epub 2021 Sep 9.

Department of Neurosurgery, Iwate Medical University School of Medicine, Yahaba, Japan.

Introduction: No clear guidelines for treating adult patients with ischemic moyamoya disease (MMD) without cerebral hemodynamic compromise such as misery perfusion have been established. Our previous prospective cohort study of adult patients with MMD without misery perfusion who were treated with medical management alone, including an antiplatelet drug, showed a recurrent ischemic event rate of 3% per 2 years. The present prospective study aimed to elucidate the 5-year clinical, cerebral perfusion, and cognitive outcomes of medical management alone for Japanese adult patients with ischemic MMD without cerebral misery perfusion by following the same patients for another 3 years. Read More

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September 2021

Role of ammonia in secondary inorganic aerosols formation at an ammonia-rich city in winter in north China: A comparative study among industry, urban, and rural sites.

Environ Pollut 2021 Sep 9;291:118151. Epub 2021 Sep 9.

Key Laboratory of Resources and Environmental Systems Optimization, Ministry of Education, College of Environmental Science and Engineering, North China Electric Power University, Beijing, 102206, China.

Ammonia is essential for the generation of secondary inorganic aerosols (SIA) in particulate matter, which affects severely the air quality in north China. In this study, PM sampling was conducted as well as gaseous pollutant concentration and meteorological parameters were measured from November 2017 to January 2018. PM concentration was highest in the industrial site (94. Read More

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September 2021

Abiotic reduction of nitrite by Fe(II): a comparison of rates and NO production.

Environ Sci Process Impacts 2021 Sep 13. Epub 2021 Sep 13.

Department of Civil and Environmental Engineering, University of Iowa, Iowa City, Iowa 52242, USA.

Abiotic reduction of nitrite (NO) by Fe(II) species (, chemodenitrification) has been demonstrated in a variety of natural environments and laboratory studies, and is a potentially significant source of atmospheric nitrous oxide (NO) emissions. It is, however, unclear how chemodenitrification rates and NO yields vary among heterogeneous Fe(II) species under similar conditions and whether abiotic reduction competes with biological NO reduction. Here, we measured rates of NO reduction and extents of NO production by several Fe(II) species under consistent, environmentally relevant conditions (, pH 7. Read More

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September 2021

First report of causing brown spots on gallnuts of in China.

Tao Ma Zixiang Yang

Plant Dis 2021 Sep 13. Epub 2021 Sep 13.

Research Institute of Resource Insects, Chinese Academy of Forestry, Kunming, Yunnan, China;

Chinese gallnuts have been used as a source of tannic acids, which are widely used in medicinal and chemical products (Zhang et al. 1999). In summer 2020, a severe outbreak of brown spots was observed on Du-ensiform gall of , at the Dongyue village, Emei county, Sichuan province, China. Read More

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September 2021

The association between female reproductive performance and leukocyte telomere length in wild Soay sheep.

Mol Ecol 2021 Sep 12. Epub 2021 Sep 12.

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3FL, UK.

Telomere length (TL), typically measured across a sample of blood cells, has emerged as an exciting potential marker of physiological state and of the costs of investment in growth and reproduction within evolutionary ecology. While there is mounting evidence from studies of wild vertebrates that short TL predicts raised subsequent mortality risk, the relationship between reproductive investment and TL is less clear cut, and previous studies report both negative and positive associations. In this study, we examined the relationship between TL and different aspects of maternal reproductive performance in a free-living population of Soay sheep. Read More

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September 2021

Functional network topology in drug resistant and well-controlled idiopathic generalized epilepsy: a resting state functional MRI study.

Brain Commun 2021 26;3(3):fcab196. Epub 2021 Aug 26.

Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.

Despite an increasing number of drug treatment options for people with idiopathic generalized epilepsy (IGE), drug resistance remains a significant issue and the mechanisms underlying it remain poorly understood. Previous studies have largely focused on potential cellular or genetic explanations for drug resistance. However, epilepsy is understood to be a network disorder and there is a growing body of literature suggesting altered topology of large-scale resting networks in people with epilepsy compared with controls. Read More

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Navigating Performance Standards for Face Mask Materials: A Custom-Built Apparatus for Measuring Particle Filtration Efficiency.

Glob Chall 2021 Aug 5:2100052. Epub 2021 Aug 5.

Centre of Excellence in Protective Equipment and Materials (CEPEM) 1280 Main St. W. Hamilton ON Canada.

Public health agencies have recommended the community use of face masks to reduce the transmission of airborne diseases like COVID-19. Virus transmission is reduced when masks act as efficient filters, thus evaluating mask particle filtration efficiency (PFE) is essential. However, the high cost and long lead times associated with purchasing turn-key PFE systems or hiring certified laboratories hampers the testing of filter materials. Read More

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Case Report: A Case Study Significance of the Reflective Parenting for the Child Development.

Front Psychol 2021 17;12:724996. Epub 2021 Aug 17.

Department of Psychology, Plovdiv University "Paisii Hilendarski, " Plovdiv, Bulgaria.

There are studies that connect the "child" in the past with the "parent" in the present through the prism of high levels of stress, guilt, anxiety. This raises the question of the experiences and internal work patterns formed in childhood and developed through parenthood at a later stage. The article (case study) presents the quality of parental capacity of a family raising a child with an autism spectrum. Read More

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Toxic effects of subacute exposure to acrylamide on motor endplates of the gastrocnemius in rats.

Toxicology 2021 Sep 9:152934. Epub 2021 Sep 9.

Department of Basic Medicine, College of life sciences and biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. Electronic address:

Acrylamide (ACR) is a recognized toxin that is known to induce neurotoxicity in humans and experimental animals. This study aimed to investigate the toxic effects of subacute exposure of the motor endplate (MEP) of the gastrocnemius in rats to ACR. All rats were randomly divided into control, 9, 18, and 36 mg/kg ACR groups, and ACR was administered by gastric gavage for 21 days. Read More

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September 2021

Accurate Dosimetry for Radiobiology.

Int J Radiat Oncol Biol Phys 2021 Sep 9. Epub 2021 Sep 9.

Medical Radiation Research Center, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705. Electronic address:

Purpose: Accurate radiation dose is required to ensure reproducibility in establishing the radiobiological effect in biological systems among institutions. The dose should be the most precise and accurate parameter of the entire process. The goal is a system to provide uniform radiation dose verification among institutions that is traceable to NIST through an ADCL. Read More

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September 2021

Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS.

Chemosphere 2021 Aug 10;287(Pt 2):131775. Epub 2021 Aug 10.

National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece. Electronic address:

Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial apex predator (Common buzzard), freshwater and marine apex predators (Eurasian otter, harbour porpoise, grey seal, harbour seal) and their potential prey (bream, roach, herring, eelpout) from northern Europe (United Kingdom, Germany, the Netherlands and Sweden) were analyzed for the presence of legacy and emerging PFAS, employing a highly sensitive liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method. Read More

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Novel insight into the potential pathogenicity of mitochondrial dysfunction resulting from PLP1 duplication mutations in patients with Pelizaeus-Merzbacher disease.

Neuroscience 2021 Sep 7. Epub 2021 Sep 7.

Department of Pediatrics, Peking University First Hospital, Beijing 100034, China; Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Peking University, Beijing 100034, China; Beijing Key Laboratory of Molecular Diagnosis and Study on Pediatric Genetic Diseases, Peking University First Hospital, Beijing 100083, China. Electronic address:

Among the hypomyelinating leukodystrophies, Pelizaeus-Merzbacher disease (PMD) is a representative disorder. The disease is caused by different types of PLP1 mutations, among which PLP1 duplication accounts for ∼70% of the mutations. Previous studies have shown that PLP1 duplications lead to PLP1 retention in the endoplasmic reticulum (ER); in parallel , recent studies have demonstrated that PLP1 duplication can also lead to mitochondrial dysfunction. Read More

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September 2021

Parameter Identification from Normal and Pathological Middle Ears Using a Tailored Parameter Identification Algorithm.

J Biomech Eng 2021 Sep 10. Epub 2021 Sep 10.

Reutlingen University, 72762 Reutlingen, Germany.

Current clinical practice is often unable to identify the causes of conductive hearing loss in the middle ear with sufficient certainty without exploratory surgery. Besides the large uncertainties due to interindividual variances, only partially understood cause-effect principles are a major reason for the hesitant use of objective methods such as wideband tympanometry in diagnosis, despite their high sensitivity to pathological changes. For a better understanding of objective metrics of the middle ear, this study presents a model that can be used to reproduce characteristic changes in metrics of the middle ear by altering local physical model parameters linked to the anatomical causes of a pathology. Read More

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September 2021

MicroRNA-124-5p delays the progression of cerebral aneurysm by regulating FoxO1.

Exp Ther Med 2021 Oct 13;22(4):1172. Epub 2021 Aug 13.

Section 2, Department of Neurosurgery, Handan Central Hospital, Handan, Hebei 056001, P.R. China.

Cerebral aneurysm (CA) is a common brain disease, and the development of cerebral aneurysm is driven by inflammation and hemodynamic stress. MicroRNA (miR)-124-5p is reported to be associated with inflammatory response in brain disease such as cerebral ischemia-reperfusion injury. However, the function and molecular mechanism of miR-124-5p in CA are not clear, thus, the effects of miR-124-5p on inflammatory response in CA were explored. Read More

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October 2021

Estimating the impact of reopening schools on the reproduction number of SARS-CoV-2 in England, using weekly contact survey data.

BMC Med 2021 09 10;19(1):233. Epub 2021 Sep 10.

Centre for Mathematical Modelling of Infectious Disease, London School of Hygiene and Tropical Medicine, London, UK.

Background: Schools were closed in England on 4 January 2021 as part of increased national restrictions to curb transmission of SARS-CoV-2. The UK government reopened schools on 8 March. Although there was evidence of lower individual-level transmission risk amongst children compared to adults, the combined effects of this with increased contact rates in school settings and the resulting impact on the overall transmission rate in the population were not clear. Read More

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September 2021

A Clinical Update on the Prognostic Effect of microRNA Biomarkers for Survival Outcome in Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis.

Cancers (Basel) 2021 Aug 29;13(17). Epub 2021 Aug 29.

Northern Territory Institute of Research and Training, Darwin, NT 0909, Australia.

: Nasopharyngeal carcinoma (NPC), a relatively uncommon malignancy in the Western world, is highly prevalent in Southeast Asia where the treatment outcomes are poor. Despite recent improvements in diagnosis and treatment locoregional control, distant metastasis and chemoresistance continue to be a significant cause of mortality. Identification of a reliable and comprehensive prognostic biomarker is highly desirable. Read More

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Effect of Powder/Water Ratio Variation on Viscosity, Tear Strength and Detail Reproduction of Dental Alginate Impression Material ( and Clinical Study).

Polymers (Basel) 2021 Aug 30;13(17). Epub 2021 Aug 30.

Restorative and Dental Materials Department, National Research Centre (NRC), Giza 1226, Egypt.

Background: Alginate impression is a common dental polymeric material, presented as powder to be mixed with water.

Aim: 1. To analyze the effect of alginate powder/water ratio variation on viscosity, tear strength and detail reproduction by tests, and 2. Read More

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Delayed Colorectal Cancer Diagnosis during the COVID-19 Pandemic in Alberta: A Framework for Analyzing Barriers to Diagnosis and Generating Evidence to Support Health System Changes Aimed at Reducing Time to Diagnosis.

Int J Environ Res Public Health 2021 08 28;18(17). Epub 2021 Aug 28.

Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2X8, Canada.

The frequency of colorectal cancer (CRC) diagnosis has decreased due to the COVID-19 pandemic. Health system planning is needed to address the backlog of undiagnosed patients. We developed a framework for analyzing barriers to diagnosis and estimating patient volumes under different system relaunch scenarios. Read More

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Does Health Literacy Reinforce Disease Knowledge Gain? A Prospective Observational Study of Hungarian COPD Patients.

J Clin Med 2021 Sep 3;10(17). Epub 2021 Sep 3.

Department of Pulmonology, Semmelweis University, 1083 Budapest, Hungary.

We set out to measure the health literacy (HL) of COPD patients using the Short Test of Functional Health Literacy (S-TOFHLA), perception-based screening questions (BHLS), and a specific disease knowledge test (COPD-Q). Our main focus is the relationship between functional HL and patients' disease-knowledge, which contributes to the clarification of the relationship between the different kinds of HL. In two prospective observational studies, 151 COPD patients (80 males, mean age: 62 ± 9 years) completed a questionnaire containing HL measurements, psychological tests (e. Read More

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September 2021

Carotenoids Do Not Protect Bacteriochlorophylls in Isolated Light-Harvesting LH2 Complexes of Photosynthetic Bacteria from Destructive Interactions with Singlet Oxygen.

Molecules 2021 Aug 24;26(17). Epub 2021 Aug 24.

Institute of Basic Biological Problems RAS, 142290 Pushchino, Russia.

The effect of singlet oxygen on light-harvesting (LH) complexes has been studied for a number of sulfur (S) and nonsulfur (S) photosynthetic bacteria. The visible/near-IR absorption spectra of the standard LH2 complexes (B800-850) of (.) (S), (. Read More

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Sports Related Concussion Impacts Speech Rate and Muscle Physiology.

Brain Inj 2021 Sep 9:1-9. Epub 2021 Sep 9.

Michigan State University, Department of Communicative Sciences and Disorders, East Lansing, MI, USA.

Objective: Establish objective and subjective speech rate and muscle function differences between athletes with and without sports related concussion (SRC) histories and provide potential motor speech evaluation in SRC.

Methods: Over 1,110 speech samples were obtained from 30, 19-22 year-old athletes who had sustained an SRC within the past 2 years and 30 pair-wise matched control athletes with no history of SRC. Speech rate was measured via average time per syllable, average unvoiced time per syllable, and expert perceptual judgment. Read More

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September 2021

Probing Contact Electrification: A Cohesively Sticky Problem.

ACS Appl Mater Interfaces 2021 Sep 9. Epub 2021 Sep 9.

Department of Chemical Engineering, The University of Melbourne, 3010 Parkville, Victoria, Australia.

Contact electrification and the triboelectric effect are complex processes for mechanical-to-electrical energy conversion, particularly for highly deformable polymers. While generating relatively low power density, contact electrification can occur at the contact-separation interface between nearly any two polymer surfaces. This ubiquitousness of surfaces enables contact electrification to be an important phenomenon to understand energy conversion and harvesting applications. Read More

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September 2021

Efficacy and safety of dissimilar acupuncture intervention time-points in treating stroke: a systematic review and network meta-analysis.

Ann Palliat Med 2021 Sep 6. Epub 2021 Sep 6.

College of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, China.

Background: Impairment of motor function and activities of daily living is very common in post-stroke patients. Acupuncture has been used in stroke for a long time. Although growing evidence supports the beneficial effects of acupuncture, there is still no clear conclusion on the optimal intervention time-point for acupuncture in stroke. Read More

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September 2021

Temperature Dependence of Sorption.

Langmuir 2021 Sep 9. Epub 2021 Sep 9.

Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan.

Understanding how sorption depends on temperature on a molecular basis has been made difficult by the coexistence of isotherm models, each assuming a different sorption mechanism and the routine application of planar, multilayer sorption models (such as Brunauer-Emmett-Teller (BET) and Guggenheim-Anderson-de Boer (GAB)) beyond their premises. Furthermore, a common observation that adsorption isotherms measured at different temperatures fall onto a single "characteristic curve" when plotted against the adsorption potential has not been given a clear explanation, due to its ambiguous foundation. Extending our recent statistical thermodynamic fluctuation theory of sorption, we have generalized the classical isosteric theory of sorption into a statistical thermodynamic fluctuation theory and clarified how sorption depends on temperature. Read More

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September 2021