Cancer Cell Int 2021 Sep 14;21(1):488. Epub 2021 Sep 14.
Department of General Surgery, Huangyan Hospital of Wenzhou Medical University, Taizhou First People's Hospital, No. 218, Hengjie Road, Huangyan District, Taizhou City, 318020, Zhejiang Province, China.
Background: We aim to identify the expression and analyze the molecular action of dysregulated lncRNA-miRNA mediated by XBP-1 in colorectal cancer (CRC).
Methods: Here, we identified XBP-1-mediated dysregulated lncRNAs and miRNAs in CRC by bioinformatics analysis. The expression level of lncRNAs and miRNA was measured using quantitative real time PCR, and the expression of XBP-1, as well as apoptosis-related proteins, were detected by western blot. Read More