Ann Allergy Asthma Immunol 2021 May 14. Epub 2021 May 14.
Allergy Research Unit, Kingston Health Sciences Centre - KGH Site, Kingston, ON, Canada; Division of Allergy & Immunology, Department of Medicine, Queen's University, Kingston, ON, Canada; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON Canada. Electronic address:
Background: Although known that oral antihistamine/pseudoephedrine combination tablets have a faster onset than intranasal corticosteroid sprays in the treatment of allergic rhinitis after the first dose, the magnitude of change has not been measured in a comparative manner. Furthermore, the sensation of sprayed liquid in the nose may lead patients to mistakenly believe that intranasal steroid sprays work instantly.
Objective: This head-to-head study was conducted to assess, numerically, nasal airflow changes provided by a single dose of loratadine/pseudoephedrine tablet (LP) and fluticasone propionate nasal spray (FP) in participants experiencing allergic rhinitis symptoms including nasal congestion. Read More