1,506 results match your criteria maximal frontal

Spatiotemporal dynamics of maximal and minimal EEG spectral power.

PLoS One 2021 20;16(7):e0253813. Epub 2021 Jul 20.

Department of Psychology, Northwestern University, Evanston, IL, United States of America.

Oscillatory neural activities are prevalent in the brain with their phase realignment contributing to the coordination of neural communication. Phase realignments may have especially strong (or weak) impact when neural activities are strongly synchronized (or desynchronized) within the interacting populations. We report that the spatiotemporal dynamics of strong regional synchronization measured as maximal EEG spectral power-referred to as activation-and strong regional desynchronization measured as minimal EEG spectral power-referred to as suppression-are characterized by the spatial segregation of small-scale and large-scale networks. Read More

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Resting posterior alpha power and adolescent major depressive disorder.

J Psychiatr Res 2021 Jul 8;141:233-240. Epub 2021 Jul 8.

Department of Psychiatry, Columbia University, New York, NY, USA; New York State Psychiatric Institute, New York, NY, USA; Division of Clinical Developmental Neuroscience, Sackler Institute, USA. Electronic address:

For several decades, resting electroencephalogram (EEG) alpha oscillations have been used to characterize neurophysiological alterations related to major depressive disorder. Prior research has generally focused on frontal alpha power and asymmetry despite resting alpha being maximal over posterior electrode sites. Research in depressed adults has shown evidence of hemispheric asymmetry for posterior alpha power, however, the resting posterior alpha-depression link among adolescents remains unclear. Read More

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The Influence of Kinesio Tape and an Ankle Brace on the Lower Extremity Joint Motion in Fatigued, Unstable Ankles during a Lateral Drop Landing.

Int J Environ Res Public Health 2021 06 4;18(11). Epub 2021 Jun 4.

Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.

Background: An unstable ankle along with plantar flexor muscle fatigue may exacerbate landing performance. External support may be an option to control the ankle motion and protect joints from injuries. Research goal: To investigate the immediate changes in the joint motion of a lower extremity under ankle plantar flexors fatigue conditions in athletes with unstable ankles using different external supports. Read More

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Status Triphasicus Versus Status Epilepticus?

J Clin Neurophysiol 2021 Jun 18. Epub 2021 Jun 18.

Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, U.S.A.; and Neurology Services, University of Miami Hospital and Clinics and Jackson Memorial Hospital, Miami, Florida, U.S.A.

Summary: Generalized periodic patterns with triphasic wave morphology, long referred to as triphasic waves [TWs], had been associated with metabolic encephalopathies, although other neurologic and systemic causes have since been identified. In a recent classification of periodic patterns, TWs were formally grouped with the generalized periodic discharges, which are often associated with ictal activity. The interpretation of generalized periodic patterns with TWs as nonictal can have significant implications in the management of comatose patients in nonconvulsive status epilepticus. Read More

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Reliability of hip muscle strength measured in principal and intermediate planes of movement.

PeerJ 2021 2;9:e11521. Epub 2021 Jun 2.

School of Health Sciences and Social Work, Griffith University, Gold Coast, Queensland, Australia.

Background: Muscle strength testing is widely used in clinical and athletic populations. Commercially available dynamometers are designed to assess strength in three principal planes (sagittal, transverse, frontal). However, the anatomy of the hip suggests muscles may only be recruited submaximally during tasks performed in these principal planes. Read More

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A Unified Functional Network Target for Deep Brain Stimulation in Obsessive-Compulsive Disorder.

Biol Psychiatry 2021 Apr 20. Epub 2021 Apr 20.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Movement Disorders and Neuromodulation Unit, Department of Neurology, Berlin, Germany; Charité - Universitätsmedizin Berlin, Einstein Center for Neurosciences Berlin, Berlin, Germany.

Background: Multiple deep brain stimulation (DBS) targets have been proposed for treating intractable obsessive-compulsive disorder (OCD). Here, we investigated whether stimulation effects of different target sites would be mediated by one common or several segregated functional brain networks.

Methods: First, seeding from active electrodes of 4 OCD patient cohorts (N = 50) receiving DBS to anterior limb of the internal capsule or subthalamic nucleus zones, optimal functional connectivity profiles for maximal Yale-Brown Obsessive Compulsive Scale improvements were calculated and cross-validated in leave-one-cohort-out and leave-one-patient-out designs. Read More

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Working memory load modulates oscillatory activity and the distribution of fast frequencies across frontal theta phase during working memory maintenance.

Neurobiol Learn Mem 2021 Jun 2;183:107476. Epub 2021 Jun 2.

Cognitive Neuroscience Laboratory, Department of Clinical Psychology and Psychobiology, Universidade de Santiago de Compostela, Santiago de Compostela, Galiza, Spain.

Working memory (WM) is a keystone of our cognitive abilities. Increasing load has been shown to dampen its performance and affect oscillatory neural activity in different frequency bands. Nevertheless, mixed results regarding fast frequencies activity and a lack of research on WM load modulations of cross-frequency phase-amplitude coupling mechanisms preclude a better understanding of the impact of increased WM load levels on brain activity as well as inter-regional communication and coordination supporting WM processes. Read More

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analysis of endocanalicular light pipe transillumination in endoscopic dacryocystorhinostomy: Anatomic considerations and cautions for the transitioning.

Orbit 2021 Jun 3:1-5. Epub 2021 Jun 3.

Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

: Localization of the lacrimal sac is a critical step during endoscopic dacryocystorhinostomy (endo-DCR). A "light pipe" can be used to transilluminate the lacrimal sac endonasally. We hypothesized that this may misguide the surgeon learning endo-DCR to create an osteotomy mostly posterior to the maxillary line if only the bone overlying the transillumination was to be removed, as the thinner lacrimal bone will transmit light more readily than the thicker maxillary bone of the frontal process of the maxilla that forms the anterior lacrimal sac fossa. Read More

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Reliability of the Single-Leg, Medial Countermovement Jump in Youth Ice Hockey Players.

Sports (Basel) 2021 May 13;9(5). Epub 2021 May 13.

Department of Kinesiology, University of Western Ontario, London, ON N6A 357, Canada.

Appropriate performance tests are critical for documenting training, fatigue and injury-related changes. Functional performance testing can provide quantitative information on specialized sport movements. The single-leg, medial countermovement jump is an objective measure of frontal plane force, velocity and power, and is particularly applicable for ice hockey players given that ice skating involves applying lateral forces. Read More

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Source analyses of axial and vestibular evoked potentials associated with brainstem-spinal reflexes show cerebellar and cortical contributions.

Neurosci Lett 2021 07 26;757:135960. Epub 2021 May 26.

Prince of Wales Clinical School, UNSW, Sydney, NSW 2052, Australia; Neuroscience Research Australia, UNSW, Sydney, NSW 2052, Australia.

In this work we examine the possible neural basis for two brainstem-spinal reflexes using source analyses of brain activity recorded over the cortex and posterior fossa. In a sample of 5 healthy adult subjects, using axial and vestibular stimulation by means of applied impulsive forces, evoked potentials were recorded with 63 channels using a 10 % cerebellar extension montage. In parallel, EMG was recorded from soleus and tibialis anterior muscles and accelerometry from the lower leg. Read More

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Prelanding movement strategies among chronic ankle instability, coper, and control subjects.

Sports Biomech 2021 May 27:1-17. Epub 2021 May 27.

Department of Exercise Sciences, Brigham Young University, Provo, UT, USA.

We describe feedforward neuromuscular control during a maximal jump landing/cutting task among groups of chronic ankle instability (CAI), coper, and uninjured control subjects. Sixty-six volunteers participated (22 CAI, 22 copers, and 22 uninjured controls). The subjects completed five trials of a maximal jump landing/cutting manoeuvre. Read More

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Skin landmarks to main cerebral structures: how to identify the main cerebral sulci? An anatomical study.

Surg Radiol Anat 2021 May 1. Epub 2021 May 1.

Department of Neurosurgery, University Hospital of Bordeaux, Place Amélie Raba-Léon, 33076, Bordeaux, France.

Purpose: Neuronavigation is used in neurosurgical practice to locate the cortical structures. If this tool is unavailable, basic anatomical knowledge should be used. Craniometry has been rarely detailed in recent literature, systematically using bony landmarks. Read More

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Lower lung-volume level induces lower vertical center of mass position and alters swimming kinematics during front-crawl swimming.

J Biomech 2021 05 9;121:110428. Epub 2021 Apr 9.

Department of Sports and Life Sciences, National Institute of Fitness and Sports in Kanoya, Kanoya, Kagoshima, Japan; Graduate School of Science and Technology, Shinshu University, Ueda, Nagano, Japan; School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia.

We examined the impact of lung-volume levels on the vertical center of mass (CoM) position and kinematics during submaximal front-crawl swimming at constant velocity. Thirteen well-trained male swimmers (21.2 ± 2. Read More

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Concurrent Validation and Reference Values of Gluteus Medius Clinical Test.

Int J Sports Phys Ther 2021 Apr 1;16(2):335-341. Epub 2021 Apr 1.

Head of the Physical Therapy Department, Minas Tenis Clube.

Context: The hip abductor muscles, mainly the gluteus medius, are responsible for controlling hip adduction in a closed kinetic chain. Frontal plane knee alignment, assessed during functional activities such squatting, jumping and running, may overload joint structures, like the anterior cruciate ligament and patellofemoral joint. The hand-held dynamometer is reliable and effective for testing the muscular strength of the hip abductors. Read More

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The apex angle of the rocker sole affects the posture and gait stability of healthy individuals.

Gait Posture 2021 05 3;86:303-310. Epub 2021 Apr 3.

Department of Informatics, Graduate School of Informatics and Engineering, The University of Electro-communications, 1-5-1 Chofugaoka, Chofu, Tokyo, 182-8585, Japan. Electronic address:

Background: Rocker sole (RS) shoes have been linked to impaired postural control. However, which features of RS design affect balance is unclear.

Research Question: Which RS design features affect standing balance and gait stability?

Methods: This study utilized an intervention and cross-over design. Read More

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5-HT receptor- and M muscarinic acetylcholine receptor-mediated activation of Gα in postmortem dorsolateral prefrontal cortex of opiate addicts.

Pharmacol Rep 2021 Apr 9. Epub 2021 Apr 9.

Laboratory of Neuropharmacology, IUNICS/IdISPa, University of the Balearic Islands (UIB), Palma de Mallorca, Spain.

Background: Chronic exposure to opiates causes the development of tolerance and physical dependence as well as persistent brain neuroplasticity. Despite a wealth of postmortem human studies for opiate addicts, little direct information regarding the functional status of serotonergic and cholinergic receptor-mediated signaling pathways in the human brain of opiate addicts is yet available.

Methods: Functional activation of Gα proteins coupled to 5-HT and M type muscarinic acetylcholine receptor (mAChR) was assessed by using the method named [S]GTPγS binding/immunoprecipitation in frontal cortical membrane preparations from postmortem human brains obtained from opiate addicts and matched controls. Read More

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Brain Structure, Cardiorespiratory Fitness, and Executive Control Changes after a 9-Week Exercise Intervention in Young Adults: A Randomized Controlled Trial.

Life (Basel) 2021 Mar 30;11(4). Epub 2021 Mar 30.

Exercise & Mental Health Laboratory, Institute of Collaborative Innovation (Sport-Psychology-Education), School of Psychology, Shenzhen University, Shenzhen 518060, China.

Cardiorespiratory fitness (CRF) is assumed to exert beneficial effects on brain structure and executive control (EC) performance. However, empirical evidence of exercise-induced cognitive enhancement is not conclusive, and the role of CRF in younger adults is not fully understood. Here, we conducted a study in which healthy young adults took part in a moderate aerobic exercise intervention program for 9 weeks (exercise group; n = 48), or control condition of non-aerobic exercise intervention (waitlist control group; n = 72). Read More

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Calvarial diploic venous channels: delineation with maximal intensity projection technique.

Surg Radiol Anat 2021 Mar 7. Epub 2021 Mar 7.

Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.

Purpose: To date, very few studies have explored the three-dimensional architecture of calvarial diploic venous channels (CDVCs). This study aimed to characterize the three-dimensional architecture of CDVCs using maximum intensity projection (MIP) images based on contrast-enhanced magnetic resonance imaging (MRI).

Methods: A total of 77 patients with intact calvarial hemispheres and underlying dura mater and dural sinuses underwent contrast-enhanced MRI. Read More

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Review of oral minoxidil as treatment of hair disorders: in search of the perfect dose.

J Eur Acad Dermatol Venereol 2021 Jul 23;35(7):1485-1492. Epub 2021 Mar 23.

Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

Topical minoxidil has been used for many years as treatment for different hair disorders. Even though it is an effective therapy, many patients show poor compliance due to the cosmesis, cost and side-effects. During the last few years, low-dose oral minoxidil has proven to be an alternative for patients with alopecia. Read More

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Side-hops challenge knee control in the frontal and transversal plane more than hops for distance or height among ACL-reconstructed individuals.

Sports Biomech 2021 Feb 15:1-18. Epub 2021 Feb 15.

Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden.

We compared knee landing mechanics with presumed relation to risk of anterior cruciate ligament (ACL) injury among three single-leg hop tests and between legs in individuals with unilateral ACL reconstruction. Thirty-four participants (>10 months' post-surgery, 23 females) performed the standardised rebound side hop (SRSH), maximal hop for distance (OLHD) and maximal vertical hop (OLVH). We calculated the following knee outcomes from motion capture and force plate data: finite helical axis inclination angles (approximates knee robustness), frontal and transversal plane angles at initial contact, peak angles of abduction and internal rotation during landing, and peak external moments of flexion, abduction and internal rotation during landing. Read More

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February 2021

Are Bioceramics the Dernier Cri in the Management of Stage 4 Developed Root? A Finite Element Analysis.

J Contemp Dent Pract 2020 Sep 1;21(9):961-969. Epub 2020 Sep 1.

Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences, Delhi, India.

Aim: To compare the stress distribution of four modalities of reinforcing the radicular space of a pulpless central incisor exhibiting stage 4 root development.

Materials And Methods: The model of a pulpless immature central incisor with a stage 4 of root development supporting periodontium was generated based on the properties. The longitudinal growth of the root was completed. Read More

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September 2020

Magnitude of vertical ground reaction force during water-based exercises in women with obesity.

Sports Biomech 2021 Feb 11:1-14. Epub 2021 Feb 11.

Department of Sports, Federal University of Pelotas, Pelotas, Brazil.

Individuals with obesity are recommended to practice physical activity with reduced weight bearing, such as water-based exercises. However, the magnitude of the vertical ground reaction force (Fz) during these exercises is unknown in this population. This study aimed to verify the magnitude of peak Fz (Fz) in women with obesity during different exercises performed in water and on land and at different intensities. Read More

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February 2021

Postmortem Analyses in a Patient With Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD): II. Histological, Lipid, and Gene Expression Outcomes in Regional Brain Tissue.

J Child Neurol 2021 Feb 9:883073820987742. Epub 2021 Feb 9.

Department of Pharmacotherapy, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.

This study has extended previous metabolic measures in postmortem tissues (frontal and parietal lobes, pons, cerebellum, hippocampus, and cerebral cortex) obtained from a 37-year-old male patient with succinic semialdehyde dehydrogenase deficiency (SSADHD) who expired from SUDEP (sudden unexplained death in epilepsy). Histopathologic characterization of fixed cortex and hippocampus revealed mild to moderate astrogliosis, especially in white matter. Analysis of total phospholipid mass in all sections of the patient revealed a 61% increase in cortex and 51% decrease in hippocampus as compared to (n = 2-4) approximately age-matched controls. Read More

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February 2021

Time-Course Evaluation of Brain Regional Mitochondrial Bioenergetics in a Pre-Clinical Model of Severe Penetrating Traumatic Brain Injury.

J Neurotrauma 2021 Mar 10. Epub 2021 Mar 10.

Brain Trauma Neuroprotection (BTN) Branch, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research (WRAIR), Silver Spring, Maryland, USA.

Mitochondrial dysfunction is a pivotal target for neuroprotection strategies for traumatic brain injury (TBI). However, comprehensive time-course evaluations of mitochondrial dysfunction are lacking in the pre-clinical penetrating TBI (PTBI) model. The current study was designed to characterize temporal responses of mitochondrial dysfunction from 30 min to 2 weeks post-injury after PTBI. Read More

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Influence of surgically assisted rapid maxillary expansion on the interdental papilla height of maxillary central incisors.

J Orofac Orthop 2021 Jan 28. Epub 2021 Jan 28.

Department of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Philips van Leydenlaan 25, 6525 EX, Nijmegen, The Netherlands.

Purpose: To evaluate the influence of orthodontic treatment with surgically assisted rapid maxillary expansion (SARME) on the interdental papilla height of maxillary central incisors.

Methods: In this retrospective study, patients who completed orthodontic treatment including SARME at the Radboud University Medical Center Orthodontic Department before December 2019 were included. Frontal intraoral photographs taken before (T1) and after completion of treatment (T2) were examined to determine the papilla height between the maxillary central incisors using the Jemt classification. Read More

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January 2021

Continuous Intraoperative Neurophysiological Monitoring of the Motor Pathways Using Depth Electrodes During Surgical Resection of an Epileptogenic Lesion: A Novel Technique.

Oper Neurosurg (Hagerstown) 2021 Apr;20(5):E379-E385

Department of Neurology, Emory University, Atlanta, Georgia.

Background And Importance: Intraoperative neurophysiological monitoring of the motor pathways during epilepsy surgery is essential to safely achieve maximal resection of the epileptogenic zone. Motor evoked potential (MEP) recording is usually performed intermittently during resection using a handheld stimulator or continuously through an electrode array placed on the motor cortex. We present a novel variation of continuous MEP acquisition through previously implanted depth electrodes in the perirolandic cortex. Read More

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Executive functional deficits during electrical stimulation of the right frontal aslant tract.

Brain Imaging Behav 2021 Jan 19. Epub 2021 Jan 19.

Department of Neurosurgery, Elisabeth-Tweesteden Hospital Tilburg, Tilburg, The Netherlands.

Direct electrical stimulation mapping was used to map executive functions during awake surgery of a patient with a right frontal low-grade glioma. We specifically targeted the frontal aslant tract, as this pathway had been infiltrated by the tumor. The right frontal aslant tract has been implicated in executive functions in the neuroscientific literature, but is yet of unknown relevance for clinical practice. Read More

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January 2021

Effects of External Load on Sagittal and Frontal Plane Lower Extremity Biomechanics During Back Squats.

J Biomech Eng 2021 May;143(5)

Department of Human Movement Sciences, Old Dominion University, 2016 Student Recreation Center, Norfolk, VA 23529.

Previous literature suggests the sticking region, the transition period between an early peak concentric velocity to a local minimum, in barbell movements may be the reason for failing repeated submaximal and maximal squats. This study determined the effects of load on lower extremity biomechanics during back squats. Twenty participants performed the NSCA's one-repetition-maximum (1RM) testing protocol, testing to supramaximum loads (failure). Read More

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5-ALA Enhanced Fluorescence-Guided Microscopic to Endoscopic Resection of Deep Frontal Subcortical Glioblastoma Multiforme.

World Neurosurg 2021 04 13;148:65. Epub 2021 Jan 13.

Department of Neurosurgery, University of Southern California, Los Angeles, California, USA.

Glioblastoma multiforme remains the most common adult primary brain tumor with a life expectancy of 15-18 months following best treatment strategies. Current paradigms incorporate maximal safe resection, chemotherapy, and radiation. Multiple variables correlate with increased survival; perhaps most notably are stepwise survival advantages following 78% and 98% extent of resection thresholds. Read More

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A Systematic Review of the Associations Between Inverse Dynamics and Musculoskeletal Modeling to Investigate Joint Loading in a Clinical Environment.

Front Bioeng Biotechnol 2020 7;8:603907. Epub 2020 Dec 7.

Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.

The assessment of knee or hip joint loading by external joint moments is mainly used to draw conclusions on clinical decision making. However, the correlation between internal and external loads has not been systematically analyzed. This systematic review aims, therefore, to clarify the relationship between external and internal joint loading measures during gait. Read More

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December 2020