Search Our Scientific Publications & Authors

Laryngoscope 2021 Apr 13. Epub 2021 Apr 13.

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.

Objective: The aim of this study was to determine the clinical outcomes and long-term stability of individualized titanium mesh combined with free flap for orbital floor reconstruction after maxillectomy and to identify the risk factors for titanium mesh exposure.

Material And Methods: The data of 66 patients who underwent maxillectomy and orbital floor defect reconstruction by individualized titanium mesh in Peking University School and Hospital of Stomatology between 2011 and 2019 were retrospectively reviewed. Postoperative ophthalmic function and success of aesthetic restoration were assessed. Read More

Mymensingh Med J 2021 Apr;30(2):555-558

Dr Aziza Jahan, Resident, MD Paediatrics, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

Treacher collins syndrome (TCS) or Franceschetti syndrome is an autosomal dominant inherited disorder with variable expressivity. It affects mainly craniofacial structure that derives from 1st and 2nd branchial arches approximately between the 20th day and 12th week of intrauterine life. This syndrome has different clinical types. Read More

Anat Sci Educ 2021 Apr 8. Epub 2021 Apr 8.

Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, People's Republic of China.

Dental anatomy is an integrated, core fundamental dental course, which prepares students for all future clinical dental courses. This study aimed to build up an online dental learning platform of micro-computed tomography-based three-dimensional (3D) tooth models with pulp cavity, and to further evaluate its effectiveness for dental anatomy education using a cohort study. First, ninety-six extracted permanent teeth were scanned by micro-computed tomography and the enamel, dentine, and pulp cavity of each was distinguished by different grey-scale intensities using Mimics software. Read More

BMC Vet Res 2021 Apr 6;17(1):144. Epub 2021 Apr 6.

Department and Clinic of Animal Surgery, Laboratory of Radiology and Ultrasonography, University of Life Sciences, Głęboka 30, 20-612, Lublin, Poland.

Background: The authors report a case of keratinized squamous cell carcinoma (SCC) in a 14-year-old dog with extensive cranial bone invasion. To our knowledge, this is the first description of such a case of cranial keratinized SCC with aggressive generalized osteolysis described in a dog.

Case Presentation: The 14-year-old dog was referred for radiological examination with suspicion of head trauma with clinical signs of head deformation, exophthalmos and nasal discharge. Read More

Int J Periodontics Restorative Dent 2021 Mar-Apr;41(2):253-259

The aim of the present case series was to evaluate the outcomes of the modified coronally advanced tunnel technique (MCAT) using the width of keratinized tissue (KTW) as an indicator to apply the connective tissue graft (CTG) specifically. Seven patients requiring treatment for the presence of multiple gingival RT1 recession defects in the maxilla were enrolled in the study. A total of 36 recessions were treated with MCAT, and the CTG was applied in 16 sites presenting < 2 mm of KTW at baseline. Read More

Rom J Morphol Embryol 2020 Jul-Sep;61(3):833-840

Discipline of Histology, Department of Morphological Sciences, Faculty of Medicine, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Discipline of Nephrology, Department of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, Romania;

In the jaws, the healing process of bone defects occurs differently compared with other anatomical sites where healing is done by the formation of scar tissue. This is due to physiological bone remodeling and continuous bone resorption and apposition. In the case of large cysts, there is an increased risk of postoperative infection due to the retraction of the blood clot on the bony walls. Read More

Wiad Lek 2021 ;74(2):291-294

I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE.

Objective: The aim: To determine the peculiarities of the morphometric parameters of suprahyoid region of the human prefetuses.

Patients And Methods: Materials and methods: Thirty specimens of human prefetuses of 14.0-80. Read More

Anticancer Res 2021 Apr;41(4):2083-2092

Private Practice in Orthodontics, Hamburg-Lokstedt, Germany.

Background/aim: Numerical aberrations of permanent dentition and dystopic tooth eruption are part of the phenotype of the tumor predisposition syndrome neurofibromatosis type 1 (NF1). In these cases, surplus tooth germs usually develop in the alveolar processes of the jaw. This report attests to the dystopic development of a dysplastic supernumerary tooth in NF1 arising outside the jaw. Read More

J Prosthet Dent 2021 Mar 29. Epub 2021 Mar 29.

Professor, Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China. Electronic address:

Statement Of Problem: Guided bone regeneration (GBR) is widely used to reconstruct peri-implant bone defects in the esthetic zone. However, the dimensional stability of this bone-biomaterial composite is not fully understood.

Purpose: The primary aim was to evaluate the hard tissue 3-dimensional (3D) stability around single implants placed with simultaneous GBR by using deproteinized bovine bone mineral (DBBM) in the anterior maxilla and explore possible influencing factors. Read More

Clin Oral Implants Res 2021 Mar 31. Epub 2021 Mar 31.

Department of Prosthetic Dentistry, University of Szeged, Szeged, Hungary.

Objective: To clinically evaluate the use of a titanium-reinforced PTFE mesh for vertical bone augmentation (VBA) of deficient alveolar ridges.

Materials And Methods: This case series documented consecutive patients treated for VBA with a newly developed PTFE mesh. VBA was performed in anterior and posterior, maxillary and mandibular arches using anorganic bovine bone combined with autogenous graft in a 1:1 ratio. Read More

Orthod Craniofac Res 2021 Mar 29. Epub 2021 Mar 29.

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

Objective: The aim of this study was to analyse the correlation between incisor alveolar bone thickness (IABT) and dentofacial characteristics or age in adult female patients with bimaxillary dentoalveolar protrusion (BDP). Evaluating the contribution of these characteristics may help to predict the IABT differences in this patient population.

Setting And Sample Population: A retrospective study whose sample comprised 80 pretreatment adult female patients with BDP (mean age 24. Read More

Int J Oral Maxillofac Surg 2021 Mar 24. Epub 2021 Mar 24.

Department of Oral and Maxillofacial Surgery, Southend University Hospital, Mid and South Essex NHS Trust, Westcliff-on-Sea, Southend-on-Sea, Essex, UK.

Oro-antral communications/fistulae (OAC/OAF) can cause significant patient morbidity, with treatment for defects greater than 5mm in size requiring surgical reconstruction. This technical note evaluates the effectiveness, and proposes the use of, the temporal extension of the buccal fat pad (TEBFP) for the closure of large OAC. The TEBFP can be an effective means of large OAC closure due to its ease of harvesting, with minimal damage to surrounding structures or aesthetic changes. Read More

Maxillofac Plast Reconstr Surg 2021 Mar 17;43(1):10. Epub 2021 Mar 17.

Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Jukheon gil 7, Gangneung, Gangwondo, 25457, Republic of Korea.

Background: Pedicled buccal fat pad (PBFP) has been used for the reconstruction of small-sized maxillary defects but cannot be used without hard tissue support on the defect larger than 4 cm × 4 cm × 3 cm.

Case Presentation: A 64-year-old man had a history of squamous cell carcinoma of the left maxilla. After removal of the posterior maxilla, a complex bone defect (size, 5 cm × 4 cm × 3 cm) was immediately reconstructed using PBFP combined with a titanium mesh. Read More

Congenit Anom (Kyoto) 2021 Mar 17. Epub 2021 Mar 17.

Department of Oral and Maxillofacial Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan.

Cleft lip and cleft alveolus are caused by incomplete fusion of the frontonasal and maxillary prominences. However, milder forms of cleft lip are rarely accompanied by cleft alveolus. Here, we report a rare case of mini-microform cleft lip with complete cleft alveolus and cleft palate. Read More

Orthod Craniofac Res 2021 Mar 12. Epub 2021 Mar 12.

Division of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.

Objective: This study aimed to quantify the 3D asymmetry of the maxilla in patients with unilateral cleft lip and palate (UCP) and investigate the defect factors responsible for the variability of the maxilla on the cleft side using a deep-learning-based CBCT image segmentation protocol.

Setting And Sample Population: Cone beam computed tomography (CBCT) images of 60 patients with UCP were acquired. The samples in this study consisted of 39 males and 21 females, with a mean age of 11. Read More

Ann Maxillofac Surg 2020 Jul-Dec;10(2):304-311. Epub 2020 Jul 2.

Department of Mechanical Engineering, University of Cape Town, Rondebosch, Cape Town, South Africa.

Introduction: The revascularized fibula free flap (RFFF) is the most popular method of postmaxillectomy reconstruction. This article proves that the use of curvilinear transport distraction osteogenesis (CTDO) is an efficacious way in closing large defects in the maxilla and a superior alternative to the RFFF.

Methods And Materials: In a prospective cohort study of six postmaxillectomy patients, CTDO was applied and the new bone (regenerate) was compared with the parent bone from which it had been regenerated. Read More

J Craniofac Surg 2021 Mar-Apr 01;32(2):e198-e202

Periodontics - European University Madrid, Spain.

Abstract: 3D printing is one of the most significant technological advancements of the modern era. Among the various surgical disciplines, this new technology has shown significant improvements in the diagnosis and treatment of many diseases. The application of 3D printing has many benefits in training, preoperative planning and education. Read More

J Int Soc Prev Community Dent 2021 Jan-Feb;11(1):98-103. Epub 2021 Jan 30.

Department of Endodontics, Faculty of Dentistry, King Abdul Aziz University, Jeddah, Saudi Arabia.

Objective: The aim of this investigation was to detect defects that may occur to Reciproc endodontic files after a single use.

Materials And Methods: A sample of convenience of Reciproc files (VDW GmbH, Munich, Germany) that were used to prepare root canals of anterior or posterior teeth were collected. The files were divided equally into two groups: Group 1 (R25) files were used to prepare mesial root canals of 50 human permanent mandibular molars, and Group 2 (R40) included 50 files that were used to prepare permanent maxillary incisor teeth. Read More

J Contemp Dent Pract 2020 Oct 1;21(10):1170-1175. Epub 2020 Oct 1.

Department of Conservative Dentistry and Endodontics, Sathyabama Dental College and Hospital, Chennai, Tamil Nadu, India.

Aim And Objective: The aim of this study was to evaluate the efficacy of novel antioxidant oregano against conventional antioxidants sodium ascorbate and green tea through comparison of the baseline weight percentage (wt%) of minerals prior to bleaching with values after bleaching protocols and antioxidant application by employing energy-dispersive X-ray spectroscopy analysis (EDAX).

Materials And Methods: Thirty noncarious, freshly extracted human permanent maxillary incisors without any visible defects were selected as samples. They were divided into three groups ( = 10) based on the antioxidant treatment received as follows: group I-10% sodium ascorbate solution, group II-10% green tea solution, and group III-5% oregano solution. Read More

BMC Surg 2021 Mar 8;21(1):120. Epub 2021 Mar 8.

Plastic Surgery Department, Shifa International Hospital, Pitras Bukhari Road H-8, Islamabad, Pakistan.

Background: Most of the head and neck cancers are time-critical and need urgent surgical treatment. Our unit is one of the departments in the region, at the forefront in treating head and neck cancers in Pakistan. We have continued treating these patients in the COVID-19 pandemic with certain modified protocols. Read More

J Oral Biol Craniofac Res 2021 Apr-Jun;11(2):277-283. Epub 2021 Feb 19.

Department of Orthodontics and Dentofacial Orthopedics, Maulana Azad Institute of Dental Sciences, New Delhi, 110002, India.

Objective: To assess the treatment outcome of custom made maxillary transport distractor appliance for closure of large alveolar clefts.

Method: A pilot study was conducted on 12 large alveolar cleft defects present in 11 non-syndromic cleft lip and palate patients (1 bilateral and 10 unilateral) in the age group of 16-25 years. All the subjects underwent pre-surgical orthodontics followed by alveolar distraction using custom-made distractor appliance. Read More

Gen Dent 2021 Mar-Apr;69(2):64-68

Taurodontism, usually associated with genetic disorders, is an anomaly in dental development in which the tooth presents with a vertically elongated pulp chamber due to an invagination failure of the Hertwig epithelial sheath. This article presents 2 case reports describing the endodontic treatment of permanent taurodontic molars in systemically healthy patients. In case 1, a maxillary left first molar presented with hypertaurodontism and 5 root canals. Read More

J Prosthodont 2021 Mar 3. Epub 2021 Mar 3.

Dean of the RCSEd Faculty of Dental Surgery, Faculty of Dental Surgery, The Royal College of Surgeons of Edinburgh, Edinburgh, UK.

The presence of a cleft lip and palate is associated with a number of complications and the oral rehabilitation for the improvement of speech, function and esthetics can involve conventional and surgical orthodontics, distraction osteogenesis, fixed and removable prosthodontics, providing obturation of open defects if required. This clinical report describes the prosthodontic management of a patient with a repaired cleft lip and palate with significant maxillary hypoplasia and primary concern of aesthetics with the use of a two-part hinged magnet retained removable prosthesis. Read More

Tissue Cell 2021 Feb 24;71:101515. Epub 2021 Feb 24.

Laboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences-I, Lebanese University, Hadath- Beirut, Lebanon. Electronic address:

Small bone defects can heal spontaneously through the bone modeling process due to their physiological environmental conditions. The bone modeling cycle preserves the reliability of the skeleton through the well-adjusted activities of its fundamental cell. Stem cells are a source of pluripotent cells with a capacity to differentiate into any tissue in the existence of a suitable medium. Read More

Dev Dyn 2021 Feb 26. Epub 2021 Feb 26.

Department of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne, Victoria, Australia.

Background: The highly conserved Grainyhead-like (Grhl) family of transcription factors play critical roles in the development of the neural tube and craniofacial skeleton. In particular, deletion of family member Grainyhead-like 2 (Grhl2) leads to mid-gestational embryonic lethality, maxillary clefting, abdominoschisis, and both cranial and caudal neural tube closure defects. These highly pleiotropic and systemic defects suggest that Grhl2 plays numerous critical developmental roles to ensure correct morphogenesis and patterning. Read More

AJNR Am J Neuroradiol 2021 Feb 25. Epub 2021 Feb 25.

From the Thyroid, Head & Neck Cancer (THANC) Foundation (M.L.S., M.G., M.H.X., M.L.U.), New York, New York.

The osteomyocutaneous iliac crest free flap is a reconstructive option for segmental mandibular or complex palatomaxillary defects. Familiarity with the radiographic appearance of free flaps such as the iliac crest is necessary for the postoperative evaluation of patients after mandibular, maxillary, or palatal reconstructions because it allows radiologists to properly monitor and interpret the appearance of the flap over time. This study presents a retrospective review of 5 patients who underwent palatomaxillary reconstruction with an iliac crest free flap at our institution. Read More

J Pain Res 2021 17;14:481-485. Epub 2021 Feb 17.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Maxillary nerve block is widely used for treating trigeminal neuralgia. Common complications of the procedure include bleeding and sensory abnormalities, but ophthalmic complications have been rarely reported. A 60-year-old woman underwent maxillary nerve block for refractory trigeminal neuralgia. Read More

Int J Prosthodont 2021 Feb 23. Epub 2021 Feb 23.

Purpose: To investigate the influence of occlusal interference in dental prosthetics using finite element analysis (FEA).

Materials And Methods: The FEA model designed for this study centered on an all-ceramic, bi-layered, fixed partial denture (FPD) retained on the maxillary first premolar and molar, with the second premolar replaced by a pontic. The surrounding structures, such as the neighboring teeth, antagonists, and periodontium, were modeled. Read More

BMJ Case Rep 2021 Feb 23;14(2). Epub 2021 Feb 23.

Pediatrics, KS Hegde Medical Academy, NITTE Deemed to be University, Mangalore, India

Single median maxillary central incisor (SMMCI) syndrome is rare. It is commonly associated with other midline defects. About 50% of children with SMMCI have short stature, associated with isolated growth hormone deficiency or panhypopituitarism. Read More

Int J Oral Maxillofac Surg 2021 Feb 16. Epub 2021 Feb 16.

University Department for Oral and Maxillofacial Surgery, Vienna General Hospital, Waehringer Guertel 18-20, 1090 Vienna, Austria.

In this study we compared the aesthetic outcome of (1) Le Fort I (LFI) osteotomy and (2) intraoral quadrangular Le Fort II (IQLFII) osteotomy for surgical correction of skeletal class III dysgnathia involving midfacial deficiency. The aim was to investigate whether laypersons see differences in facial changes that occur due to variations of the osteotomy cuts. The patient collectives consisted of 23 patients in each group. Read More